Hartmut Geiger, a biochemist and stem cell researcher at Ulm University Hospital is using genetic methods to investigate the molecular basis of the physiological ageing of haematopoietic stem cells. After having spent a period in Cincinnati, Geiger is currently head of the clinical research group "Molecular and cellular ageing – from the mechanisms of action to clinical perspectives".
At Ulm University, which is home to one of the few adult stem cell priorities in Germany, Geiger will be able to find many cooperation partners in his search to clarify the correlation between ageing and cancer. He will focus on the haematopoietic system, first in physiological systems and then in genetically modified models. If he is able to come up with physiological explanations as to why older people generally suffer more from leukaemia or cancer, then this would help the researchers to find ways of delaying the ageing process or of adapting cancer therapies to a patient’s age.Literature: Geiger, H. et al.: Stem Cells, Aging, Niche, Adhesion and Cdc42, in: Cell Cycle 6:8, s. 884-887, 15 April 2007.