The peptides, which consist of between 12 and 50 amino acids, are very interesting tools for the treatment of infections because they can destroy both gram negative and gram positive bacteria, as well as fungi, viruses and parasites. In addition, they also have important immunological functions. Although they have been known since the 1960s, exactly how they operate is still unknown. This is also true for the short peptide chains being studied by Kai Hilpert's research group.

Bacteria are surrounded by a protective layer above the actual cell membrane. It is about 10 times thicker than the miniature proteins. "We are able to show that the peptides have an effect on the bacterial membrane, though it is perhaps surprising that they cannot enter the membrane," said Kai Hilpert. The IBG scientist and his team are currently working on optimising and automating the screening method which will later be used to screen 8,000 to 10,000 substances per week. The IBG researchers hope that this screening will then provide them with highly effective substances capable of fighting off infections while attached  to the surface of implants.