By blocking the cells’ own ‘recycling system’, cancer cells that are particularly resistant to radiation therapy can be made to become susceptible to this kind of treatment again, said Dr. Anja Apel of the Department of Surgery at the University Hospital in Heidelberg who has been able to prove this in laboratory experiments. The research results hint at a new strategy that might be able to kill particularly malignant tumours.
Literature: Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy. Anja Apel, Ingrid Herr, Heinz Schwarz, H. Peter Rodemann, and Andreas Mayer. Cancer Res 2008 68: 1485-1494