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They have the super cell

In the “Year of Science”, which is being celebrated in the city of Constance in 2009, the company Trenzyme, located in the Constance industrial park, is a prime example of science and industry working successfully hand in hand on the Nycomed campus.

It all started at the University of Constance. In 2000, a group of students established the company Trenzyme as a spin-off from the university’s microbiology department. The company’s mission was to be a service provider for big pharmaceutical companies. “And this is still the case today,” said Reinhold Horlacher, one of the two Trenzyme directors.

Dr. Reinhold Horlacher, Trenzyme's CEO © Hanser

One of the company’s activities is the production of proteins from genes and the testing of drugs with cell cultures, for example in the search for a new pain reliever. In the laboratories of the Constance-based company, proteins that are known to trigger pain are isolated from DNA and the researchers then attempt to discover the chemical interactions that prevent the transmission of pain from one body cell to another.

At Trenzyme, science and business have always worked hand in hand. The career path of the second company boss, Konstantin Matentzoglu, is further evidence of this connection. During his doctorate at the University of Constance, Matentzoglu developed a method that enables the uninterrupted production of greater numbers of proteins – whatever the external influences on the cell are. It took two to three years of research before the new method worked efficiently. “This new method clearly places us in the forefront of progress. We have been able to reduce production time by fifty percent, which is what makes the method so attractive to our clients,” said Reinhold Horlacher. Around half of the company’s clients are based in Switzerland.

”Since the publication of the new method in a scientific journal early in 2009, a large number of people have contacted us,” said Horlacher pointing out Trenzyme’s upward trend, which is also reflected by the company’s growing demand for workspace. At the end of 2007, the University of Constance was no longer big enough to accommodate the company and so it moved to the Nycomed campus on Byk-Gulden-Straße where it now has 440 square metres at its disposal. The number of staff has grown from five to eight and Trenzyme is hoping to create four more jobs, despite the ongoing economic downturn. “This is our goal for 2009,” said Horlacher, who envisages a promising future for the Nycomed campus.

Website address: https://www.gesundheitsindustrie-bw.de/en/article/press-release/they-have-the-super-cell