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Viscofan BioEngineering: Cell culture inserts with a collagen membrane

Viscofan BioEngineering is the first company to market cell culture inserts for the cultivation of cells and tissues that are entirely made from collagen. In contrast to traditional PTFE membranes, Viscofan´s cell culture inserts do not need to be coated with collagen prior to use. The new collagen inserts are extremely suitable for the cultivation of adherent primary cells such as cardiomyocytes, neurons, fibroblasts, cell lines, stem cells as well as facilitating the formation of tissue structures.

Cell culture inserts with collagen membrane. © Viscofan BioEngineering

Just like the company's Collagen Cell Carriers (CCC), the new membranes are made of largely intact, non-crosslinked native collagen fibres that are processed on the industrial scale into thin sheets of highly stable and elastic film. The new, self-supporting collagen inserts consist of a collagen membrane that is fixed into a spherical carrier and can be easily removed after cell cultivation for subsequent research applications, for example in the field of regenerative medicine. Implantation studies involving different animal species and tissues have already shown the excellent biocompatibility of the collagen matrices in vivo.

The cell-covered membranes can be directly embedded in histological slices and dyed. Investigations have shown that the collagen membrane is permeable to nutrients, which enables it to be used for specific applications, including the cultivation of cells for use in skin models or in studies assessing transmembrane transport. This opens up completely new possibilities for barrier experiments and co-cultivation. The new insert is of particular interest for cryoconservation and implantation studies.

Viscofan BioEngineering 

Viscofan BioEngineering is a business unit of Viscofan S.A., a worldwide leader in the manufacture of collagen, cellulose, fibres and plastic products for the food industry. The company has facilities in Europe, America and Asia, and sells its products in more than 120 countries all over the world. It is listed on the Spanish Stock Market.

Viscofan BioEngineering focuses its activities on the development of innovative biomaterials on the basis of collagen for application in cell culture, tissue engineering and regenerative medicine. Besides the further development of its innovative collagen scaffolds, Viscofan BioEngineering has entered into collaborations with several academic groups in Germany and Spain to research and develop the use of these biomaterials in selected medical indications, such as myocardial infarction and age-related macular degeneration (AMD).

The company has offices and laboratories in Weinheim (Germany) as part of Naturin Viscofan GmbH, the German subsidiary of Viscofan S.A. and collagen centre of excellence for the whole group.

Contact:

Viscofan BioEngineering
Dr. Dieter Falkenburg
Badeniastraße 13
69469 Weinheim

Tel.: + 49-6201-860
Fax: + 49-6201-86485
E-mail: contact(at)bio.viscofan.com

Website address: https://www.gesundheitsindustrie-bw.de/en/article/press-release/viscofan-bioengineering-cell-culture-inserts-with-a-collagen-membrane