Epifadin from the nasal microbiome - 28/03/2024 From the nose: novel antibiotic substance discovered Antibiotics are becoming an increasingly blunt weapon against infectious diseases. The number of (multi-)resistant germs has been rising rapidly for years and even reserve antibiotics no longer work. Researchers at the University of Tübingen have now isolated a completely new antibiotic substance called epifadin from the microbiome of the human nose. It is effective against many different bacteria - including the dangerous hospital MRSA.https://www.gesundheitsindustrie-bw.de/en/article/news/nose-novel-antibiotic-substance-discovered
Event - 18/04/2024 4C Close up – Selective contracts as a business model, underestimated or overrated? Online, Webinar https://www.gesundheitsindustrie-bw.de/en/event/4c-close-selective-contracts-business-model-underestimated-or-overrated
Press release - 14/03/2024 Next milestone in the treatment of liver tumors and acute and chronic liver diseases The results of a Tuebingen-led study raise hope that a newly developed drug could herald a new era in oncological liver surgery and transplantation. The drug could even have the potential to significantly improve the treatment of acute and chronic liver diseases. The drug candidate "HRX-215" is a so-called MKK4 inhibitor, i.e. the drug inhibits the MKK4 protein found in liver cells and thus leads to an increase in the regeneration of…https://www.gesundheitsindustrie-bw.de/en/article/press-release/next-milestone-treatment-liver-tumors-and-acute-and-chronic-liver-diseases
Stem cell research - 14/03/2024 Using organoids to gain a better clinical understanding of pancreatic cancer Prof. Dr. Alexander Kleger carries out translational research at Ulm University Hospital to gain a better understanding of pancreatic ductal adenocarcinoma (PDAC) and develop individualised treatments. He and his team are using organoid models and stem cell-based systems and have succeeded in simultaneously cultivating all three main cell types of the pancreas from pluripotent stem cells.https://www.gesundheitsindustrie-bw.de/en/article/news/using-organoids-gain-better-clinical-understanding-pancreatic-cancer
Press release - 05/03/2024 New Center for Synthetic Genomics Applying and developing new technologies for DNA synthesis to pave the way for producing entire artificial genomes – that is the goal of a new interdisciplinary center, 'Center for Synthetic Genomics', that is being established at Heidelberg University, Karlsruhe Institute of Technology (KIT), and Johannes Gutenberg University Mainz (JGU). https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-center-synthetic-genomics
Press release - 04/03/2024 First Step Toward Early Diagnosis of Metastasis Team involving the University of Freiburg has developed a new analytical method for the basement membrane in human lungs.https://www.gesundheitsindustrie-bw.de/en/article/press-release/first-step-toward-early-diagnosis-metastasis
Press release - 04/03/2024 Heidelberg Pharma Announces Royalty Financing Agreement with HealthCare Royalty for up to USD 115 million HealthCare Royalty to purchase royalties from worldwide sales of Telix Pharmaceuticals’ imaging diagnostic agent ZircaixTM (TLX250-CDx) Heidelberg Pharma is eligible to receive up to USD 115 million in three near-term tranches Cumulative royalties sold are capped at a maximum valuehttps://www.gesundheitsindustrie-bw.de/en/article/press-release/heidelberg-pharma-announces-royalty-financing-agreement-healthcare-royalty-usd-115-million
Press release - 01/03/2024 Using Data to Improve Understanding of Relationships between Proteins and Diseases Working with a new Emmy Noether Group, Dr. Pascal Schlosser is investigating how machine learning can aid in understanding the complex relationships between genes, proteins, and diseases.https://www.gesundheitsindustrie-bw.de/en/article/press-release/using-data-improve-understanding-relationships-between-proteins-and-diseases
Neurosciences - 28/02/2024 Mesh microelectrode arrays: research with brain organoids on a new level How does the brain work? Brain organoids are derived from pluripotent stem cells and regarded as valuable model systems that can depict some aspects of neurological functioning. Dr. Peter Jones from NMI together with Dr. Thomas Rauen from the MPI for Molecular Biomedicine in Münster, has taken organoid research to a new level. His novel mesh microelectrode array (Mesh-MEA) greatly improves the growth and electrophysiological analysis of tissue.https://www.gesundheitsindustrie-bw.de/en/article/news/mesh-microelectrode-arrays-research-brain-organoids-new-level
Press release - 22/02/2024 A new approach to recording cellular activities In living cells, a vast number of transient events occur simultaneously. The recording of these activities is a prerequisite for a molecular understanding of life. Scientists at the MPI for Medical Research in Heidelberg and their collaboration partners have created a novel technology that allows cellular events to be recorded through chemical labeling with fluorescent dyes for later analysis, opening up new ways to study cellular physiology.https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-approach-recording-cellular-activities
Event - 08/04/2024 - 12/04/2024 DMEA Business Meetings 2024 Online and at DMEA in Berlin (10.04.24), Matchmaking https://www.gesundheitsindustrie-bw.de/en/event/dmea-business-meetings-2024
Event - 01/03/2024 SHIFT-HUB Internationals Bokerage Event Online, Information and Matchmaking https://www.gesundheitsindustrie-bw.de/en/event/shift-hub-internationals-bokerage-event
Press release - 15/02/2024 Modelling the spread of diseases Computer scientists from the Cluster of Excellence Collective Behaviour developed a model, that explains how collective scenarios such as diseases may proceed.https://www.gesundheitsindustrie-bw.de/en/article/press-release/modelling-spread-diseases
Robotics in medicine - 15/02/2024 Copied from the pangolin: innovative flexible miniature robot for minimally invasive applications Wireless miniature robots that can penetrate hard-to-reach areas of the body for the purpose of medical treatment are currently still a vision of the future. Researchers at the Max Planck Institute for Intelligent Systems in Stuttgart have now constructed the first flexible prototype modelled on the pangolin, which can generate heat and stop bleeding, kill tumour cells or release "cargo" in the model system.https://www.gesundheitsindustrie-bw.de/en/article/news/copied-pangolin-innovative-flexible-miniature-robot-minimally-invasive-applications
Event - 18/09/2024 - 20/09/2024 GCSB 2024 German Conference on Synthetic Biology 2024 Regensburg, Kongress/Symposium https://www.gesundheitsindustrie-bw.de/en/event/gcsb-2024-german-conference-synthetic-biology-2024
Event - 10/07/2024 - 11/07/2024 Curious2024 – Future Insight™ Conference Mainz, Kongress/Symposium https://www.gesundheitsindustrie-bw.de/en/event/curious-2024-future-insight-conference
Press release - 12/02/2024 AI-supported image analysis: metrics determine quality How well do the algorithms used in the AI-supported analysis of medical images perform their tasks? This depends to a large extent on the metrics used to evaluate their performance. An international consortium led by scientists from the German Cancer Research Center and the National Center for Tumor Diseases has compiled the knowledge available worldwide on the specific strengths, weaknesses and limitations of the various validation metrics.https://www.gesundheitsindustrie-bw.de/en/article/news/ai-supported-image-analysis-metrics-determine-quality
Press release - 07/02/2024 The unexpected long-term consequences of female fertility The constant remodeling of the organs of the female reproductive tract during the reproductive cycle leads to fibrosis and chronic inflammation over the years. Scientists from the German Cancer Research Center (DKFZ) have now uncovered these unexpected long-term consequences of female reproductive function in mice. The results have been published in the scientific journal CELL.https://www.gesundheitsindustrie-bw.de/en/article/press-release/die-unerwartete-auswirkung-der-weiblichen-fortpflanzungsfaehigkeit
Press release - 06/02/2024 New T-FINDER Platform Provides Deep Insights Into T Cell Responses Against Novel Cancer Vaccine BioMed X and the Universitätsmedizin Mannheim announced today the publication of two manuscripts in the field of cancer immunology in the journal Science Advances. The work is based on a collaboration bet- ween both institutions and researchers at the German Cancer Research Center (DKFZ), the Heidelberg Uni- versity, and the Helmholtz Institute for Translational Oncology (HI-TRON).https://www.gesundheitsindustrie-bw.de/en/article/press-release/neue-t-finder-plattform-liefert-tiefe-einblicke-t-zell-antwort-auf-neuartigen-krebsimpfstoff
Press release - 02/02/2024 Epigenetic status determines metastasis Scientists from the German Cancer Research Center (DKFZ) and Medical Faculty Mannheim of the Heidelberg University investigated in mice how spreading tumor cells behave at the site of metastasis: Some tumor cells immediately start to form metastases. Others leave the blood vessel and may then enter a long period of dormancy. What determines which path the cancer cells take is their epigenetic status. https://www.gesundheitsindustrie-bw.de/en/article/press-release/epigenetischer-status-entscheidet-ueber-metastasierung
Press release - 02/02/2024 University of Stuttgart successful with cluster draft proposals The German Research Foundation (DFG) has announced the first pivotal decisions for the "Clusters of Excellence" funding line as part of the Excellence Strategy of the German federal and state governments. The University of Stuttgart has been given the green light for two new cluster initiatives. https://www.gesundheitsindustrie-bw.de/en/article/press-release/universitaet-stuttgart-mit-clusterskizzen-erfolgreich
Funding EU Joint Programme - Neurodegenerative Disease Research (JPND): Mechanisms and measurement of disease progression in the early phase of neurodegenerative diseases Funding programme, Funded by: EU JPND I BMBF, sb_search.searchresult.label.programSubmissionDate: 05/03/2024 https://www.gesundheitsindustrie-bw.de/en/database/funding/eu-joint-programme-neurodegenerative-disease-research-jpnd-mechanisms-and-measurement-disease-progression-early-phase-neurodegen
Press release - 31/01/2024 Precursor of Cholesterol Protects Cancer Cells From Cell Death and Makes them Aggressive A precursor of cholesterol can protect cancer cells from a form of cell death known as ferroptosis. Scientists of the University of Würzburg, the German Cancer Research Center (DKFZ), and the Stem Cell Institute HI-STEM* published this finding in the journal Nature. The results opens up exciting prospects for further improving the treatment of cancer and other diseases associated with oxidative stress and ferroptosis.https://www.gesundheitsindustrie-bw.de/en/article/press-release/cholesterin-vorstufe-schuetzt-krebszellen-vor-zelltod-und-macht-sie-aggressiver
Waste recycling in the healthcare sector - 30/01/2024 Sustainability in medical technology: a particular challenge Quality and safety of medical care are top priorities in the healthcare sector. However, this is often at the expense of climate protection, as not only are energy and raw material consumption very high, but so is the amount of waste generated due to the large number of disposable products. Sustainable product design and improved recycling strategies are therefore required to reduce waste and the CO2 footprint.https://www.gesundheitsindustrie-bw.de/en/article/news/sustainability-medical-technology-particular-challenge
Event - 22/10/2024 2nd Biointelligence Congress in Stuttgart Stuttgart (Germany), Kongress/Symposium https://www.gesundheitsindustrie-bw.de/en/event/2nd-biointelligence-congress-stuttgart
Press release - 18/01/2024 Indicator for liver health status identified A high-fat, high-sugar diet damages the liver in the long term. Scientists at the German Cancer Research Center (DKFZ) have now identified a characteristic change in the molecular signaling pathways of liver cells in mice that were exposed to such a diet for weeks. It fuels the division activity of hepatocytes and correlates with the risk of patients suffering liver failure after liver surgery.https://www.gesundheitsindustrie-bw.de/en/article/press-release/indicator-liver-health-status-identified
Press release - 17/01/2024 Immatics Announces Pricing of $175 Million Public Offering Immatics N.V. (NASDAQ: IMTX, “Immatics”), a clinical-stage biopharmaceutical company active in the discovery and development of T cell-redirecting cancer immunotherapies, announced today the pricing of an underwritten public offering of 15,925,000 ordinary shares at a public offering price of $11.00 per share. https://www.gesundheitsindustrie-bw.de/en/article/press-release/immatics-announces-pricing-175-dollar-million-public-offering
Press release - 17/01/2024 AI-based support system for skin cancer diagnostics explains its decisions Artificial intelligence (AI) can help dermatologists to detect skin cancer. However, many dermatologists distrust the algorithms' decisions, which they cannot comprehend. Scientists at the German Cancer Research Center have now developed an AI-based support system for skin cancer diagnostics that explains its decisions.https://www.gesundheitsindustrie-bw.de/en/article/press-release/ai-based-support-system-skin-cancer-diagnostics-explains-its-decisions
Press release - 15/01/2024 Maturation instead of cell death: Defective signalling pathways disrupt immune cell development Researchers at the Faculty of Medicine of the University of Freiburg discover key factor in the development of immune cells. New approaches for the treatment of ALPS.https://www.gesundheitsindustrie-bw.de/en/article/maturation-instead-cell-death-defective-signalling-pathways-disrupt-immune-cell-development
Event - 18/09/2024 - 20/09/2024 58th Annual Conference of the German Society for Biomedical Engineering (BMT 2024) Stuttgart, Kongress/Symposium https://www.gesundheitsindustrie-bw.de/en/event/58th-annual-conference-german-society-biomedical-engineering-bmt-2024
Health Data Futures project - 11/01/2024 Creating a network of trust In the three-nation project "Health Data Futures", stakeholders and experts from Germany, France and Switzerland have launched a series of patient-centred innovations. Using various future scenarios, the project partners may be able to come up with even more scenarios.https://www.gesundheitsindustrie-bw.de/en/article/news/creating-network-trust
Press release - 10/01/2024 MedTech Company KARL STORZ Acquires British AI Specialist Innersight Labs The family-owned MedTech company KARL STORZ announces the acquisition of the innovative software manufacturer Innersight Labs Ltd. (ISL) headquartered in London. In addition to state-of-the-art endoscopes, high-end medical devices, and integrated solutions for the operating room, KARL STORZ is also continuing to expand in innovative software solutions. https://www.gesundheitsindustrie-bw.de/en/article/press-release/medtech-company-karl-storz-acquires-british-ai-specialist-innersight-labs
Press release - 08/01/2024 Brain tumors in children: Cancer cells become less aggressive as they migrate within the tumor Certain brain tumors in small children contain cells that develop very similarly to normal brain cells and others that have already developed malignantly, depending on where they are located within the tumor. https://www.gesundheitsindustrie-bw.de/en/article/press-release/hirntumoren-bei-kindern-krebszellen-werden-auf-ihrer-wanderung-im-tumor-weniger-aggressiv
Press release - 05/01/2024 Prostate cancer: Newly-developed inhibitor shows massive potential More than 65,000 men fall ill with prostate cancer each year in Germany. Twelve thousand of them develop a treatment-resistant form which eventually ends in death. Now, a team of researchers from the Medical Faculty at the University of Freiburg has developed an active substance that might in future represent a new treatment option. https://www.gesundheitsindustrie-bw.de/en/article/press-release/prostate-cancer-newly-developed-inhibitor-shows-massive-potential
Press release - 05/01/2024 How memories are formed in the brain – a new role for the internal compass University of Tübingen neuroscientists discover new functions of head-direction cells suggesting they may contribute to episodic memory formation.https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-memories-are-formed-brain-new-role-internal-compass
Press release - 04/01/2024 Key player in viral heart inflammation discovered Inflammation of the heart muscle, also known as myocarditis, is a serious consequence of a viral infection. This can impede the heart’s ability to pump blood in the long term. In a current study, researchers of the Faculty of Medicine of the University of Freiburg have discovered a new approach for treating myocarditis. https://www.gesundheitsindustrie-bw.de/en/article/press-release/key-player-viral-heart-inflammation-discovered
Press release - 03/01/2024 Reprogrammed fat cells support tumor growth Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the Weizmann Institute in Israel and at the German Cancer Research Center (DKFZ) have now shown that p53-mutated mouse breast cancer cells reprogram fat cells.https://www.gesundheitsindustrie-bw.de/en/article/press-release/reprogrammed-fat-cells-support-tumor-growth
Event - 03/06/2024 - 06/06/2024 BIO International Convention 2024 San Diego, United States, Kongress/Symposium https://www.gesundheitsindustrie-bw.de/en/event/bio-international-convention-2024
Event - 27/05/2024 - 28/05/2024 Neuro4D Mainz, Conference https://www.gesundheitsindustrie-bw.de/en/event/neuro4d
Event - 16/04/2024 - 17/04/2024 German Biotechnology Days 2024 Berlin, Kongress/Symposium https://www.gesundheitsindustrie-bw.de/en/event/german-biotechnology-days-2024
Event - 18/03/2024 - 20/03/2024 BioInspired Materials BioINSP 2024 Löwenstein und Online, Kongress/Symposium https://www.gesundheitsindustrie-bw.de/en/event/bioinspired-materials-bioinsp-2024
Event - 18/03/2024 - 20/03/2024 BIO-EUROPE SPRING® Barcelona, Registration deadline: 15/03/2024, Messe https://www.gesundheitsindustrie-bw.de/en/event/bio-europe-spring-r
Event - 18/06/2024 - 20/06/2024 MedtecLIVE with T4M 2024 Stuttgart, Messe https://www.gesundheitsindustrie-bw.de/en/event/medteclive-t4m-2024
Press release - 18/12/2023 Researchers discover novel antibiotic substance from the human nose For the first time, the active substance epifadin has been isolated at the University of Tübingen – Epifadin is produced by specific bacteria in the nose and on the skin of humans, has an antibiotic effect, and is the first example of a previously unknown antimicrobial compound class.https://www.gesundheitsindustrie-bw.de/en/article/press-release/researchers-discover-novel-antibiotic-substance-human-nose
Event - 09/04/2024 - 11/04/2024 DMEA - Connecting Digital Health 2024 Berlin, Messe https://www.gesundheitsindustrie-bw.de/en/event/dmea-connectiong-digital-health-2024
All-enzyme hydrogels in action - 13/12/2023 Biocatalytic foams enable the sustainable synthesis of complex molecules Conventional chemical synthesis processes consume large amounts of energy and environmentally harmful solvents. Prof. Dr. Christof Niemeyer’s team at the Karlsruhe Institute of Technology has generated porous, solid foams from crosslinked enzymes that allow the production of high-quality compounds under significantly more environmentally friendly conditions. The novel biocatalysts are also extremely resistant and have a long shelf life.https://www.gesundheitsindustrie-bw.de/en/article/news/biocatalytic-foams-enable-sustainable-synthesis-complex-molecules
Press release - 11/12/2023 Heidelberg center for personalized medicine achieves the highest quality standards The German Cancer Society has certified the Center for Personalized Medicine (ZPM) at Heidelberg University Hospital. At the ZPM Heidelberg, patients with advanced and rare cancers and, in future, people with severe chronic inflammatory diseases will receive a molecular genetic analysis. The detailed information can open up new treatment options for those affected.https://www.gesundheitsindustrie-bw.de/en/article/press-release/zentrum-fuer-personalisierte-medizin-heidelberg-erfuellt-hoechste-qualitaetsstandards
Press release - 08/12/2023 Where does chronic pain come from? Professor Dr. Rohini Kuner from the Medical Faculty of Heidelberg University receives the Leibniz Prize of the German Research Foundation (DFG).https://www.gesundheitsindustrie-bw.de/en/article/press-release/woher-kommen-chronische-schmerzen
Funding NutriBrain: Modulation of brain ageing through nutrition and healthy lifestyle Funding programme, Funded by: ISCIII & BMBF, sb_search.searchresult.label.programSubmissionDate: 15/01/2024 https://www.gesundheitsindustrie-bw.de/en/database/funding/richtlinie-zur-foerderung-von-transnationalen-forschungsprojekten-zur-modulation-der-alterung-des-gehirns-durch-ernaehrung-und-e
Computer-assisted genome mining - 04/12/2023 Natural product genomics opens up new avenues in the search for antibiotics Antibiotic-resistant pathogens are increasingly endangering our health. Since most of the drugs currently in use are based on secondary metabolites produced by bacteria or fungi, the research group of Prof. Dr. Nadine Ziemert in Tübingen is developing bioinformatic tools to specifically search the genome of these organisms for previously unknown antimicrobial agents.https://www.gesundheitsindustrie-bw.de/en/article/news/natural-product-genomics-opens-new-avenues-search-antibiotics