A research consortium was established at the Stuttgart Research Center Systems Biology SRCSB at the University of Stuttgart in January 2013 with the goal of establishing models that help predict the action of targeted therapeutics. The scientists combine molecular biology experiments with complex mathematical models in order to achieve a holistic understanding of disease and therapy.
The NMI Natural and Medical Sciences Institute in Reutlingen organised its biannual MEA conference from 8 to 11 July 2008. More than 200 developers and microelectrode array users from 18 countries came together in Reutlingen to present their latest developments and results.
Boehringer Ingelheim is hoping to find ways to use anti-inflammatory mechanisms of action to improve the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. Clinical studies will show what kind of improvements patients can expect from the substances, which are currently at different stages of development. Drugs to widen the bronchia, marketed by Boehringer Ingelheim, will in the medium term become indispensable in the treatment of chronic obstructive pulmonary diseases and asthma.
amcure GmbH has identified a new compound with a new efficacy profile against pancreatic cancer. Animal experiments have shown promising results: the drug candidate successfully prevents tumour growth and destroys existing metastases. The company, which was spun out from the Karlsruhe Institute of Technology (KIT) in 2011, is now working on its first financing round and is looking for new investors. At the same time it is carefully planning its future with the aim of developing the new angiogenesis inhibitor in a structured and precise way.
Trying to get a second opinion from a medical colleague who is at home preparing dinner may be quite a challenge, especially when the colleague does not have access to the necessary image data. This has now become easier in the field of radiology thanks to a mobile app called mRay, which provides a reliable way for radiologists to share medical images on mobile devices.
The NMI in Reutlingen is one of the most prestigious research institutes in Germany, “a beacon of applied research” as the Minister of Economic Affairs recently called the institute. This success is no accident: for 25 years now, the institute with its interdisciplinary team has been working efficiently and actively towards this achievement. Moreover, it greatly succeeded in bridging science and industry.
Spectroscopic methods have been used for many decades in scientific research to obtain a wealth of information about chemical substances, substance mixtures and their reaction processes. Micro-biolytics GmbH from Esslingen have successfully developed a spectroscopic method that combines innovative technologies. The method enables the highly accurate and sensitive measurement of aqueous samples.
Scientists at the University Hospital in Heidelberg have discovered a hepatitis B virus peptide that can prevent viral infections in a mouse model. A team led by Professor Stephan Urban is developing a virus blocker against hepatitis B infections. Despite vaccinations every year about 750000 people die from the consequences of hepatitis B infections.
The impact of digital health applications on public health is not yet well documented despite the growing number of health apps on the market. In a report called “Digital-Health-Anwendungen für Bürger: Kontext, Typologie und Relevanz aus Public-Health-Perspektive”, the Bertelsmann Foundation has developed a classification system to facilitate further research and evaluation of digital health applications.
Lena Maier-Hein from the German Cancer Research Center (DKFZ) helps physicians get better vision during minimally-invasive surgery. Using novel methods of image analysis, she wants to provide additional image information for surgeons. Thus, they can better differentiate tumors from healthy tissue and execute safer surgical tumor therapies. Maier-Hein now receives the Prize of the Berlin-Brandenburg Academy of Sciences and Humanities, which is donated by the Monika Kutzner Foundation.
What causes stress for some, actually speeds others like extremophilic bacteria up. They love it hot, sour or salty, toxic substances like heavy metals also do them good and even give them energy. As molecular and systems biology techniques get better and better, industry is also becoming increasingly interested in these exotic organisms. What potential does knowing the biochemistry of extremophilic bacteria have for the pharmaceutical, cosmetics and sanitary articles industries? Whatever the answer might turn out to be, there is certainly a growing trend towards using extremophilic microbes in academic and industrial research.
The field of medicine often requires materials that need to be sterile at the same time as having low thermal stability. The Institute of Plasma Research at the University of Stuttgart has developed a dry-heat plasma sterilisation method that is a faster, more effective and less dangerous alternative to previously used methods.
First aid at the site of an accident can save many lives. Initial assistance is very often given by non-experts. In order to help these first-aiders in what are difficult circumstances, Karl Küfner GmbH & Co. KG from Albstadt and the HSG-IMIT (Institut für Mikro- und Informationstechnik) from Villingen-Schwenningen have developed a respiratory flow sensor for first-aiders which gives visual and acoustic information during resuscitation.
The speed dating format is no longer just a popular and simple dating method for lonely hearts, but has also become a rewarding way for establishing new business contacts and connections quickly and efficiently. BIOPRO Baden-Württemberg chose speed networking, as speed dating is called in the corporate world, for its recent Meet & Match event on pharmaceutical process technology, which took place on 15th March 2016 with the support of Bosch Packaging Technology in Crailsheim.
Researchers have discovered two new TBE transmission pathways: the first related to the consumption of raw milk and raw milk cheese that can cause encephalitis, and the second is another tick species that can pass on the TBE virus, thus increasing the risk of contracting the disease even in winter.
It is difficult to imagine how Ochsenhausen-based Labor Dr. Merk und Kollegen (LMK) would be able to develop, produce and test medical products for bacterial and viral contaminations without using cell cultures. The medium-sized company also produces viruses for testing and has stored more than 80 different viruses – enveloped and non-enveloped ones, animal and human pathogens – at -80˚C.
Sleep-related breathing problems can in the long term even lead to cardiac infarction or stroke. A new technology from TNI medical AG puts a stop to the discomforts of a mask by giving people a seminal solution.
Almost 15 percent of an estimated seven million diabetes mellitus patients in Germany suffer from diabetic foot syndrome DFS. It is associated with damage to the foot nerves and blood vessels as well as the presence of chronic wounds which in thousands of cases every year precede lower leg amputations. The Konstanz-based company MTS Medical has developed a shock wave therapy system that has the potential to considerably reduce the number of amputations in the foreseeable future.
Healthcare in Germany is quite good. Pharmaceutical and biotechnology companies carry out research in order to improve it further. The question is, how can a fair price for innovative drugs be determined? BIOPRO Baden-Württemberg GmbH has talked to Dr. Manfred Caeser, a specialist in pricing and reimbursement at LSCN Ltd.
A trade fair turns 20 and an industrial sector is coming of age. Where does BIO stand today? The number of exhibitors has slightly decreased the conference is characterised by general themes and trends and partnering has become the most important and indispensable part of the global event for biotechnology. What was once a gold rush atmosphere has given way to an experienced self-confidence about the economic importance of biotechnology.
Quantum biology has the potential to become the next big research coup. Professor Martin Plenio, 46, director of the Institute of Theoretical Physics at Ulm University and one of the world’s leading quantum technologists, is right at the forefront. He has been Alexander von Humboldt Professor since 2009, and holds a part-time professorship at Imperial College London, where he was formerly chair of quantum physics.
The five university hospitals in Baden-Württemberg are aiming to pool their expertise on rare diseases in order to be able to improve and speed up patient treatment. The first Treatment and Research Centre for Rare Diseases (ZSE) was established in Germany in January 2010, and the first coordination workshop was held in July 2010. At the July meeting in Tübingen and a subsequent meeting held at the University of Freiburg, the partners discussed their common goals.
Although standing upright and moving forward may appear to be simple, they are in fact complex activities that are not yet understood in detail. Even less is known about how we hop, run and jump. Researchers at the Stuttgart-based Institute of Sport and Movement Science are looking into the ways the musculoskeletal system interacts to create movements as well as studying the effect of disorders. Computer simulation is one of the principal tools being used by the researchers to investigate human motion.
Scientists at the BioQuant centre in Heidelberg have developed an automatic particle tracking method that can be used for time-resolved two- and three-dimensional microscope image data. This powerful computational method achieved the best overall result in an international competition that compared different methods for the quantitative tracking of the position of moving biological particles.