Article - 24/03/2014 Vaccine against papillomaviruses protects from skin cancer Papillomaviruses are thought to cause non-melanoma skin cancer in people exposed to UV radiation, especially those who have suppressed immune systems. Researchers from the German Cancer Research Center (DKFZ) and the Charité University Hospital in Berlin have developed a vaccine that protects mice against such skin tumours. The vaccine is even effective in mice that have previously been infected with papillomaviruses and that have suppressed…https://www.gesundheitsindustrie-bw.de/en/article/news/vaccine-against-papillomaviruses-protects-from-skin-cancer
Article - 10/06/2013 Stem-cell tests to provide protection to unborn babies The development of unborn babies may already be impaired in the womb by pollutants from the environment food and drugs to which their mothers are exposed. Reliable and informative toxicity tests are necessary in order to assess and prevent the effects toxic substances may have on unborn babies. Biologist Dr. Tanja Waldmann from Konstanz University is developing toxicity test systems based on human embryonic stem cells which contribute to improved…https://www.gesundheitsindustrie-bw.de/en/article/news/stem-cell-tests-to-provide-protection-to-unborn-babies
Press release - 10/02/2008 First Baden-Württemberg university approved for embryonic stem cell research The biochemist Prof. Marcel Leist from Constance is the first Baden-Württemberg scientist to be authorised to undertake research using embryonic stem cells. Leist is investigating the effect of drugs and chemicals on human nerve cells.https://www.gesundheitsindustrie-bw.de/en/article/press-release/first-baden-wuerttemberg-university-approved-for-embryonic-stem-cell-research
Article - 07/01/2013 HepaChip: a promising tool for assessing adverse drug effects Liver damage is one of the most common adverse drug effects. Since results obtained with animal experiments can only be transferred to the situation in humans to a limited extent, there is a need for cell-based systems that model human organ function as closely as possible. The new HepaChip, developed by researchers at the NMI in Reutlingen on the basis of human liver and endothelial cells is able to do just this.https://www.gesundheitsindustrie-bw.de/en/article/news/hepachip-a-promising-tool-for-assessing-adverse-drug-effects
Article - 02/04/2012 Looking for the molecular conductors of neuroembryogenesis Tissue development in areas such as the nervous system can be likened to the arrangement of various elements in a concert. Genetic control centres play a key role in coordinating which pieces of music are played in which order. These control centres regulate the expression of genes. A team of researchers led by Prof. Dr. Uwe Strähle from the Karlsruhe Institute of Technology KIT uses zebrafish to understand the gene networks that control…https://www.gesundheitsindustrie-bw.de/en/article/news/looking-for-the-molecular-conductors-of-neuroembryogenesis
Article - 07/06/2017 A gene that regulates body heat and fat storage Researchers from Heidelberg have shown that the organismal balance between heat production and energy storage is regulated by a gene called THADA. In animal experiments, knocking out the THADA gene leads to excessive food intake, obesity and sensitivity to cold. As humans spread throughout the world and settled in different climate zones, THADA was exposed to high selection pressure due to evolutionary adaptation. This explains why human…https://www.gesundheitsindustrie-bw.de/en/article/news/a-gene-that-regulates-body-heat-and-fat-storage
Article - 24/05/2010 Nose drops replace transplantation Dr. Lusine Danielyan a scientist from Tübingen has developed a method that enables her to administer therapeutic cells for the treatment of neurodegenerative diseases to animals without requiring syringes or surgery. The animals simply snort the cell suspension. In September 2009 Danielyan received the Baden-Württemberg Research Prize for Alternative and Complementary Methods to Animal Testing for her development.https://www.gesundheitsindustrie-bw.de/en/article/news/nose-drops-replace-transplantation
Article - 24/05/2010 A long path from development to worldwide acceptance In cooperation with the Johns Hopkins Bloomberg School of Public Health Baltimore the University of Constance has established the Centre for Alternatives to Animal Testing Europe CAAT-EU in Constance. The goal of the transatlantic cooperation is to establish new and innovative methods to replace the use of laboratory animals in studies to combine the skills of the partners to provide a better safer and more human future for humans and animals…https://www.gesundheitsindustrie-bw.de/en/article/news/a-long-path-from-development-to-worldwide-acceptance
Article - 25/01/2010 Intelligent use of suitable biomarkers How quickly does a pharmaceutical substance exert its effect? What mechanisms does it use to exert its effect on people and how long does it remain active? In a team headed by Prof. Dr. Martin Elmlinger Nycomed GmbH has developed an efficient biomarker discovery concept specially adapted to the companys requirements and designed to clarify such questions. The concept is specifically geared to the phases and requirements of the companys projects.…https://www.gesundheitsindustrie-bw.de/en/article/news/intelligent-use-of-suitable-biomarkers
Article - 22/10/2012 The crème de la crème of contact allergy tests goes in vitro As of 2013 all cosmetic products containing a chemical with inherent skin sensitisation potential must be tested without the traditional animal testing. Prof. Dr. Stefan Martin from the Department of Dermatology at the University of Freiburg Medical Centre and his partners have been looking for alternatives to animal testing and have come up with the most specific in vitro test there has ever been. The researchers involved in the project have…https://www.gesundheitsindustrie-bw.de/en/article/news/the-cr-me-de-la-cr-me-of-contact-allergy-tests-goes-in-vitro
Article - 22/06/2015 3D bioprinting: replicating the shape of bone parts Prof. Dr. Günter Finkenzeller, head of the Research and Tissue Engineering Laboratory in the Department of Plastic and Hand Surgery at the Freiburg University Medical Centre, and Dr. Peter Koltay from the Department of Microsystems Engineering (IMTEK) at the University of Freiburg, are being given German Research Foundation (DFG) funds for a period of three years to develop a 3D printing technique for functional bone tissue containing blood…https://www.gesundheitsindustrie-bw.de/en/article/news/3d-bioprinting-replicating-the-shape-of-bone-parts
Press release - 04/07/2008 Bracco Imaging: specialist in diagnostic imaging In future small bubbles will allow the identification of pathological alterations at a very early stage. Molecular imaging methods developed by Bracco Imaging S.p.A. use a new ultrasound contrast agent. The German subsidiary of the company Bracco Imaging Deutschland GmbH based in Constance develops and sells contrast agents.https://www.gesundheitsindustrie-bw.de/en/article/press-release/bracco-imaging-specialist-in-diagnostic-imaging
Article - 02/07/2012 amcure GmbH is working on a new compound against pancreatic cancer amcure GmbH has identified a new compound with a new efficacy profile against pancreatic cancer. Animal experiments have shown promising results: the drug candidate successfully prevents tumour growth and destroys existing metastases. The company, which was spun out from the Karlsruhe Institute of Technology (KIT) in 2011, is now working on its first financing round and is looking for new investors. At the same time it is carefully planning its…https://www.gesundheitsindustrie-bw.de/en/article/news/amcure-gmbh-is-working-on-a-new-compound-against-pancreatic-cancer
Article - 21/08/2009 Patenting and clinical trials go hand in hand Back when he was doing his degree thesis at the German Cancer Research Centre in Heidelberg the immunologist Prof. Peter Öhlschläger who now works at the University of Constance laid down the basic principles for developing an artificial gene for the treatment of cervical cancer. Prof. Öhlschläger is currently in the process of filing a patent for DNA vaccines for HPV. In the following interview the scientist says that the greatest challenges are…https://www.gesundheitsindustrie-bw.de/en/article/news/patenting-and-clinical-trials-go-hand-in-hand
Press release - 21/03/2011 Polymer brushes with mini proteins protect implants Patients who have had surgical implants are at risk of developing serious complications due to bacterial infections. This affects around two to six per cent of patients with implants. Scientists from the KIT Institute of Functional Interfaces (IFG) have now succeeded in developing a protective layer that prevents bacteria from adhering to implants and creating dangerous biofilms that can lead to serious infections. The protective layer has proven…https://www.gesundheitsindustrie-bw.de/en/article/press-release/polymer-brushes-with-mini-proteins-protect-implants
Article - 05/04/2009 JOTEC – artificial blood vessel specialist JOTEC GmbH a medical device company based in Hechingen has a broad range of solutions on offer for the therapy of vascular diseases including artificial blood vessels and stentgrafts and is an international leader in this field. The company not only produces traditional vascular grafts from high-quality plastics but also absorbable bioartificial vascular grafts and cell-coated grafts made from biomaterials. Such an approach is currently unique in…https://www.gesundheitsindustrie-bw.de/en/article/news/jotec-artificial-blood-vessel-specialist
Article - 22/08/2017 Transgenic mice in influenza research – risk assessment and vaccine development A research team from Freiburg is developing a method for identifying human influenza viruses of animal origin. This could potentially improve measures taken to prevent imminent pandemics. The researchers are working with genetically modified mice. Transgenic mice also play a role in the development of a ’universal’ influenza vaccine. https://www.gesundheitsindustrie-bw.de/en/article/news/transgenic-mice-in-influenza-research-risk-assessment-and-vaccine-development
Article - 04/04/2008 Cell models for human hearts wanted A consortium of two universities two applied research institutes and a research-based pharmaceutical company is looking for innovative cellular models of the human heart with the aim of developing better methods for drug testing. https://www.gesundheitsindustrie-bw.de/en/article/news/cell-models-for-human-hearts-wanted
Article - 15/04/2010 Bone-hard basic research for an ageing society Osteoporotic bones not only break very easily, they also heal badly when a fracture occurs. A fractured femur neck might mean that elderly patients have to remain bedridden for a long period and maybe even need nursing care. Fractures that heal badly, in combination with other diseases, frequently lead to a fatal outcome. A panregional team of researchers, including researchers from Ulm, has been working together since 2007 on basic research into…https://www.gesundheitsindustrie-bw.de/en/article/news/bone-hard-basic-research-for-an-ageing-society
Press release - 08/09/2009 Angiogenesis as a key for tissue engineering The German Research Foundation is to fund a research priority of the Department of Plastic Surgery at the Freiburg University Medical Centre. Researchers around the world working in the area of regenerative medicine are all equally hopeful of generating tissue replacements using modern tissue engineering. The development of tissue cells on carrier materials seems quite promising. However, tissue-engineered implants are often rejected by patients…https://www.gesundheitsindustrie-bw.de/en/article/press-release/angiogenesis-as-a-key-for-tissue-engineering
Dossier - 26/08/2009 Model organisms Given that everything is very individual in nature, how can a biologist come up with general statements about how life functions? The answers can only be found using models that represent the entire whole. Modern research uses representative species from the kingdom of bacteria, fungi, plants and animals to glean information about fundamental biological principles. How can the knowledge gained be transferred to other organisms, including humans?…https://www.gesundheitsindustrie-bw.de/en/article/dossier/model-organisms
Article - 28/03/2010 Acrovis biostructures: because the beginning of a process is crucial Targeted substance design using an advanced platform technology that takes into account the natural dynamics of pharmaceutical substances and targets early on during the discovery process – this is what the Ulm-based biopharmaceutical company Acrovis biostructures GmbH offers. Acrovis has all the instruments needed to be able to optimally determine the structure of pharmaceutical substances.https://www.gesundheitsindustrie-bw.de/en/article/news/acrovis-biostructures-because-the-beginning-of-a-process-is-crucial
Article - 18/02/2008 Baden-Württemberg to fund MediCyte research MediCyte GmbH based in the Heidelberg Technology Park is among the winners of the Baden-Württemberg Ministry of Science Research and the Arts biotechnology funding programme. The company will establish innovative cell culture systems.https://www.gesundheitsindustrie-bw.de/en/article/news/baden-wuerttemberg-to-fund-medicyte-research
Press release - 22/07/2013 BIOPRO Baden-Württemberg's international relations bring Heidelberg-based Medicyte GmbH in contact with new distribution partner BIOPRO Baden-Württembergs business development activities have led to the establishment of a new distribution partnership between Heidelberg-based Medicyte GmbH and Dutch Westburg BV. When BIOPRO searches for international partners for Baden-Württemberg companies the state agency often makes use of its international network partners and in this case BIOPROs contact with the Netherlands Business Support Office Stuttgart NBSO brought the desired…https://www.gesundheitsindustrie-bw.de/en/article/press-release/biopro-baden-wuerttemberg-s-international-relations-bring-heidelberg-based-medicyte-gmbh-in-contact
Article - 11/01/2016 Study shows correlation between intestinal gene activity and obesity People with obesity suffer from more than just health problems related to their weight. They often feel socially stigmatised because their disease is often seen as a self-inflicted condition. A new study by the University of Hohenheim in cooperation with the eSwiss Medical and Surgical Center in St. Gallen now shows that severe obesity is closely associated with gene activity in the intestinal tissue. This activity is responsible for producing…https://www.gesundheitsindustrie-bw.de/en/article/news/studie-zeigt-zusammenhang-zwischen-gen-aktivitaet-im-darm-und-uebergewicht