Article - 28/02/2011 Contact dermatitis – removing a leg from a tripod Contact dermatitis is one of the most frequent occupational skin reactions resulting from exposure to allergens. Chronic allergic reactions to environmental allergens might sometimes become job- or life-threatening. Prof. Dr. Stefan Martin and his group of researchers in the Allergy Research Group of the Department of Dermatology at the Freiburg University Medical Centre are investigating the molecular mechanisms underlying the disease. One of…https://www.gesundheitsindustrie-bw.de/en/article/news/contact-dermatitis-removing-a-leg-from-a-tripod
Article - 19/11/2015 Immune cells are reprogrammed in Alzheimer’s brains Scientists from the Hertie Institute for Clinical Brain Research at the University of Tübingen are pursuing an innovative treatment approach for Alzheimer’s disease using immune cells to eliminate the protein deposits that are the hallmark of Alzheimer’s. Dr. Jonas Neher and his team tested whether exchanging brain-specific immune cells with fresh, more active cells has a positive effect on the disease. https://www.gesundheitsindustrie-bw.de/en/article/news/immune-cells-are-reprogrammed-in-alzheimers-brains
Press release - 05/11/2014 Orphan drug status for Synovo's immune modulator SYD003 The European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA) have granted orphan drug designation to Synovo's investigational compound SYD003, a first in class tumour-targeted immune modulator.https://www.gesundheitsindustrie-bw.de/en/article/press-release/orphan-drug-status-for-synovo-s-immune-modulator-syd003
Press release - 28/01/2010 Kenta and Rentschler to develop antibodies against hospital-acquired infections The young Swiss company Kenta Biotech will work with the Laupheim-based contract manufacturer Rentschler to develop a fully human monoclonal antibody against methicillin-resistant Staphylococcus aureus (MRSA).https://www.gesundheitsindustrie-bw.de/en/article/press-release/kenta-and-rentschler-to-develop-antibodies-against-hospital-acquired-infections
Press release - 21/07/2010 One Million for Cancer Research from Manfred Lautenschläger Foundation When Harald zur Hausen was awarded the Nobel Prize for Medicine in 2008, Manfred Lautenschläger spontaneously offered to support the Nobel laureate’s scientific work by funding a new research team. These funds will now go to Angelika Riemer, a young scientist who plans to advance the development of a vaccine which is able to cure existing infections with carcinogenic human papillomaviruses at the German Cancer Research Center (Deutsches…https://www.gesundheitsindustrie-bw.de/en/article/press-release/one-million-for-cancer-research-from-manfred-lautenschlaeger-foundation
Article - 01/08/2010 Manfred Kist – 25 years of fascination for a stomach bacterium Helicobacter pylori is a genus of bacteria that inhabits the human stomach. The bacteria can cause duodenal and gastric ulcers and are also linked to the development of gastric cancer. Prof. Dr. Manfred Kist from the Freiburg University Medical Centre has spent around 25 years of his scientific career on investigating H. pylori a bent rod-shaped bacterium.https://www.gesundheitsindustrie-bw.de/en/article/news/manfred-kist-25-years-of-fascination-for-a-stomach-bacterium
Article - 10/02/2014 HOT Screen GmbH - models for studying diseases HOT Screen GmbH from Reutlingen Germany develops human organotypical HOT cell culture models related to the human immune system for the assessment of drug activity profiles and the selection of suitable drug candidates. The sophisticated models are made with differentiated cells and can be adapted to a broad range of different diseases - including rheumatoid arthritis osteoarthritis Crohns disease neurodermatitis COPD asthma and many others. https://www.gesundheitsindustrie-bw.de/en/article/news/hot-screen-gmbh-models-for-studying-diseases
Press release - 12/07/2021 Hijacked immune activator promotes growth and spread of colorectal cancer Through a complex, self-reinforcing feedback mechanism, colorectal cancer cells make room for their own expansion by driving surrounding healthy intestinal cells to death - while simultaneously fueling their own growth. This feedback loop is driven by an activator of the innate immune system. Researchers from the German Cancer Research Center (DKFZ) and the University of Heidelberg discovered this mechanism in the intestinal tissue of fruit…https://www.gesundheitsindustrie-bw.de/en/article/press-release/hijacked-immune-activator-promotes-growth-and-spread-colorectal-cancer
Article - 03/07/2010 Erbasens: Using the power of nature Before setting up her own company biologist Dr. Elke Schulz amassed a wealth of knowledge in the pharmaceutical industry. Now she harnesses the power of plants to develop and sell dietary supplements and natural cosmetics. Her company Erbasens specialises in combining high-quality oils and plant essences to create products such as Paramirum that safeguards the effectiveness of the immune system and promotes the bodys defence systems.https://www.gesundheitsindustrie-bw.de/en/article/news/erbasens-using-the-power-of-nature
Article - 22/08/2016 Ad-O-Lytics – a new biotech start-up from Ulm A few years ago, Florian Kreppel developed a therapeutic approach that combined genetic vaccines with molecular address labels. It worked quite well, but the resulting product did not have the anticipated immunising properties and was put on the backburner. Now Kreppel's group of researchers is nearing completion of another project. The researchers plan to use a patented virotherapeutic platform technology for cancer treatment to establish a…https://www.gesundheitsindustrie-bw.de/en/article/news/ad-o-lytics-a-new-biotech-start-up-from-ulm
Press release - 18/01/2021 How a protein variant could explain resistance to sleeping sickness drug A specific variant of the surface protein VSG of African trypanosomes, the causative agents of sleeping sickness, is associated with resistance to the important drug Suramin. Scientists at the German Cancer Research Center have now been able to find a possible explanation for the formation of resistance based on the crystal structure of this protein variant.https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-protein-variant-could-explain-resistance-sleeping-sickness-drug
Infection control - 07/01/2021 Gene accordions as potential markers for pathogenic properties Bacteria must react to changes in the environment in order to survive. This is partly done by adapting genetic material, for example by multiplying and shortening individual genome segments. The research group led by Dr. Simon Heilbronner from the Interfaculty Institute of Microbiology and Infection Medicine at the University of Tübingen has shown that these so-called gene accordions are frequently found in the bacterium Staphylococcus aureus.https://www.gesundheitsindustrie-bw.de/en/article/news/gene-accordions-potential-markers-pathogenic-properties
New method for analysing blood samples - 26/11/2020 Personalised therapy monitoring for malignant melanomas Immunotherapy has greatly improved the survival chances of patients with malignant melanoma. A study has now begun at the Department of Dermatology at the University Hospital of Tübingen to develop a way to monitor the course of treatment as effectively as possible. It involves personalised monitoring using liquid biopsies in addition to conventional PET/CT examinations. This analysis procedure of blood samples could enable closer monitoring of…https://www.gesundheitsindustrie-bw.de/en/article/news/personalised-therapy-monitoring-malignant-melanomas
Dossier - 06/12/2019 Microbiome: human health is closely connected with our microbial communities People have 1.3 times more microorganisms than body cells. This microbial community influences how we digest our food, how active our immune system is, as well as whether we tend to be more anxious or curious. A number of diseases have also been shown to be associated with a disturbed microbiome. Researchers still have a long way to go before the knowledge acquired can be used for developing therapies.https://www.gesundheitsindustrie-bw.de/en/article/dossier/microbiome-human-health-closely-connected-with-microbial-communities
Press release - 15/07/2021 Mechanism for differentiation of specific immune cell types discovered Under certain conditions, our immune system can efficiently fight off infectious diseases and cancer. T cells, especially the gamma delta T cell type, play an important role in this. The issue is that this cell type is extremely infrequent in the human body. Researchers at the University Hospital Tübingen, the University of Heidelberg and the European Molecular Biology Laboratory (EMBL) have now succeeded in finding the cause for the formation of…https://www.gesundheitsindustrie-bw.de/en/article/press-release/mechanism-differentiation-specific-immune-cell-types-discovered
Press release - 16/03/2009 ZKRD: Germans are generous haematopoietic stem cell donors German citizens made as many as 4.166 haematopoietic stem cell donations in 2008. The cells were donated in order to help patients suffering from leukaemia as well as other malignant blood or immune system diseases. “Haematopoietic stem cell donations are often the only chance of a cure for many of these sufferers,” explained Dr. Dr. Carlheinz Müller, Managing Director of the Central German Bone Marrow Donor Registry (ZKRD). https://www.gesundheitsindustrie-bw.de/en/article/press-release/zkrd-germans-are-generous-haematopoietic-stem-cell-donors
KyooBe Tech GmbH - 08/10/2020 Next generation vaccine production For decades, conventional inactivated vaccines have been produced by killing pathogens with toxic chemicals. However, this process often changes the surface structure of the pathogens to such an extent that the immune system is only able to induce a weak response. KyooBe Tech GmbH is offering a method that uses low-energy electrons to inactivate pathogens. Vaccines produced this way are much higher quality, making them safer and more effective.https://www.gesundheitsindustrie-bw.de/en/article/news/next-generation-vaccine-production
Article - 30/10/2018 Eucor – bringing the European Campus to life Enrolling at one university and being able to use the services of a total of five universities is unique in the European Research Area. A model project called Eucor - The European Campus offers students and young scientists this opportunity at universities in the Germany-France-Switzerland border triangle, which simultaneously acts as a borderless academic area for the sciences. https://www.gesundheitsindustrie-bw.de/en/article/news/eucor-bringing-the-european-campus-to-life
Press release - 05/03/2011 Research prize for the gene therapy of rare diseases The Eva Luise and Horst Köhler Foundation for People with Rare Diseases has awarded the 2011 Eva Luise Köhler Research Prize, which includes prize money of 50,000 euros, to an interdisciplinary team of researchers: Professor Dr. Christoph Klein, Department of Paediatric Haematology and Oncology at the Hannover Medical School (MHH), Professor Dr. Christopher Baum, Department of Experimental Haematology (MHH), Professor Dr. Christoph von Kalle,…https://www.gesundheitsindustrie-bw.de/en/article/press-release/research-prize-for-the-gene-therapy-of-rare-diseases
Press release - 08/04/2020 “Access checker” remotely measures body temperature in addition to heart and breathing rate An innovative measurement method is helping to detect people infected with coronavirus from a safe distance. It detects fever, increased pulse rates and fast breathing without endangering the person conducting the testing. Fraunhofer IPA and Fraunhofer IAO are currently testing the procedure at the Robert Bosch Hospital in Stuttgart.https://www.gesundheitsindustrie-bw.de/en/article/press-release/access-checker-misst-koerpertemperatur-herz-und-atemfrequenz-aus-der-ferne
Article - 19/05/2008 "Fast-track" route to a PhD degree The Chemical Biology graduate school at Constance University was officially opened on 7th May 2008. It was created as part of Germanys excellence initiative and has been training doctoral students since the beginning of April 2008.https://www.gesundheitsindustrie-bw.de/en/article/press-release/fast-track-route-to-a-phd-degree
Article - 22/10/2012 The crème de la crème of contact allergy tests goes in vitro As of 2013 all cosmetic products containing a chemical with inherent skin sensitisation potential must be tested without the traditional animal testing. Prof. Dr. Stefan Martin from the Department of Dermatology at the University of Freiburg Medical Centre and his partners have been looking for alternatives to animal testing and have come up with the most specific in vitro test there has ever been. The researchers involved in the project have…https://www.gesundheitsindustrie-bw.de/en/article/news/the-cr-me-de-la-cr-me-of-contact-allergy-tests-goes-in-vitro
Press release - 30/03/2009 Stem Cells: Deathly Awakening by Interferon Interferon-alpha, a messenger substance of the immune system, awakens dormant hematopoietic stem cells in the bone marrow to become active, thus making them vulnerable for the effect of many drugs. This finding was published in Nature by researchers from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) jointly with colleagues from Lausanne. The researchers suppose that this might also be a way to stimulate tumor stem…https://www.gesundheitsindustrie-bw.de/en/article/press-release/stem-cells-deathly-awakening-by-interferon
Article - 06/07/2015 Using mosses to produce medicines Human disease can be treated with substances from traditional medicinal plants or with molecular pharming products. Molecular pharming uses genetic engineering techniques to insert genes into plants or animals that would otherwise not express these genes. These transgenics can then be used to produce therapeutic proteins such as antibodies. Dr. Eva Decker from the University of Freiburg and her team have now successfully produced a key protein of…https://www.gesundheitsindustrie-bw.de/en/article/news/using-mosses-to-produce-medicines
Press release - 12/10/2011 Autoimmune Diseases Affect Cancer Risk In a recently published study, scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have calculated the interrelations between autoimmune diseases and cancer of the digestive tract. They discovered that many autoimmune diseases increase the cancer risk, while others, such as rheumatism, are associated with a significantly lower bowel cancer risk. These differing impacts on cancer risk may be attributable to the…https://www.gesundheitsindustrie-bw.de/en/article/press-release/autoimmune-diseases-affect-cancer-risk