Healthcare industry

Press release - 04/07/2018

Phase-I-trial approved for novel stem cell therapy for patients with ischemic cardiomyopathy

Viscofan BioEngineering, the biomedical business unit of the world market leader for collagenous sausage casings Viscofan announced today that the Spanish Agency for Medicines (AEMPS) has given green light to carry out a clinical phase-I-trial with Viscofan BioEngineering’s first product for regenerative medicine. The novel therapy consisting of stem cells on a collagenous carrier membrane can now be tested on ten patients suffering from severe…

Article - 19/03/2018

Regenerative medicine: curing rather than simply treating diseases

Some scientists refer to the latest developments in the field of regenerative medicine as the "next revolution in medicine". With the help of gene therapies or stem cells, regenerative medicine aims not only to treat disease symptoms, but to cure them at source. Some approaches are already being used to treat patients and several others are close to application.

Article - 21/02/2018

HepaRegeniX – a start-up is taking it up a step!

HepaRegeniX, a biotech company founded in 2016, specialises in developing drugs that restore the regenerative capacity of diseased livers. The three founders of the biotech start-up, Prof. Dr. Lars Zender, Prof. Dr. Stefan Laufer and Dr. Wolfgang Albrecht, anticipate starting clinical testing of the first drug candidate in 2019.

Press release - 12/12/2017

BRAIN AG and Mannheim University develop 3D skin models for health care and cosmetics

Research collaboration in project M2Aind for new real-time and high-resolution screening technologies of 3D skin spheroids. Mannheim University of Applied Sciences builds on expertise in 3D cell culture and advanced live cell imaging. BRAIN contributes unique skin reporter cells, screening compound libraries and market knowledge. Review article in Journal of Cellular Biotechnology.

Press release - 05/09/2017

Cell marking opens up a window into the body

A new and particularly reliable method for marking cells can simplify research into diseases such as myocardial infarction, diabetes or Alzheimer's and reduce the use of test animals: Scientists from the University of Tübingen have developed a method by which they can target specific cell types in mice and monitor their behavior using positron emission tomography (PET). PET-based cell tracking allows scientists to observe complex life…

Article - 26/01/2017

Freiburg researchers transform skin cells into renal cells

A team of researchers from Freiburg has used direct programming to successfully produce kidney-like cells very similar to natural renal tubular cells in terms of appearance and function. These cells are thus a promising alternative to kidney cells isolated from animals and cells differentiated from embryonic stem cells. The reprogrammed kidney cells can be used, for example, for pharmacological and toxicological tests and investigating the…

Article - 27/06/2016

A nasal spray for treating neurodegenerative diseases

Neuroscientists from Heidelberg have created the scientific foundations for a nasal spray that can stabilise the dendrites of nerve cells, thus reducing nerve damage and brain function losses following a stroke. Prof. Dr. Hilmar Bading and his team received the 2016 German BioRegions Innovation Prize for their invention and have set up a company called FundaMental Pharma to further accelerate the development of a marketable medicinal product.

Article - 21/03/2016

Shock wave therapy gives hope to many men

Although the approval of vasodilatory drugs made available an effective medicine for treating erectile dysfunction, not all men respond to this type of treatment. MTS Medical UG from Konstanz has developed a therapeutic device that means that these men can now get help too. What's more, the device has no adverse health effects.

Article - 17/12/2015

Inhibition of bromodomain affects stem cell differentiation

DNA methylation and histone modification are epigenetic mechanisms that affect gene transcription. Moreover, protein complexes can regulate gene expression by modifying chromatin structure and function. Dr. Thomas Günther and his team from the Center for Clinical Research at the Freiburg University Medical Center are studying the effect of the inhibitor PFI-3 on the BAF complex. This protein complex modifies chromatin structure and controls the…

Press release - 16/11/2015

The Baden-Württemberg healthcare industry – a strong economic power

(Stuttgart – 16th November 2015) BIOPRO Baden-Württemberg has just published its latest analysis of the Baden-Württemberg healthcare industry including comprehensive facts and figures. Baden-Württemberg continues to be one of the top locations for medical technology, pharma and biotechnology in Germany.

Article - 03/09/2015

Pattern formation: How undifferentiated cell clusters develop orderly structures

Dr. Patrick Müller explores cellular signalling pathways that turn undifferentiated cell clusters into orderly structures as embryos develop. Supported by an ERC grant, the Max Planck researcher from Tübingen uses a broad range of methods from the fields of genetics, biophysics, mathematics and the computer sciences for his investigations. Regenerative medicine is one field that particularly stands to benefit from Müller’s findings.

Article - 01/06/2015

High-tech fibres for organ and tissue regeneration

Biologically degradable polymers can be electrically spun into a type of fleece that can be used as a scaffold and growth matrix for living cells. This fleece can be used to replace diseased or damaged tissue. In the field of cardiovascular medicine, the fleece can be used to produce new heart valves and tissue.

Dossier - 09/03/2015

Advances in the study and treatment of liver diseases

Liver diseases are often underestimated despite being quite common and potentially having serious and even life-threatening consequences, especially in chronic cases. The most common causes of liver diseases are hepatitis viruses, excessive alcohol consumption, and obesity; congenital or autoimmune liver diseases are quite rare. Thanks to advances in medical research, diseases such as hepatitis B and C can be treated effectively. Fewer advances…

Article - 22/12/2014

Large-scale urology project: cell therapy for the treatment of stress incontinence

The first and so far only clinical DFG research group on urology is being coordinated by a team from Tübingen. The team is developing a cell-based therapy for the regeneration of the urethral sphincter. Clinicians, life scientists and engineers are working together to try and find a causal therapy of stress incontinence.

Dossier - 10/11/2014

Cell and gene therapies: from bench to bedside

While cell therapy has become standard treatment for a number of blood cancers, most cell and gene therapy approaches for the treatment of hereditary and metabolic diseases, neurodegenerative disorders and cancer are still in the experimental phases or early clinical trials. However, recent successes give rise to the hope that cell and gene therapies will in future make important contributions to previously incurable diseases.

Article - 19/05/2014

Amedrix establishes new collagen and implant production technology

Amedrix GmbH, which is based in the Life Science Center in Esslingen and currently has a staff of eight people, develops innovative acellular medical products on the basis of animal collagen. The company's ChondroFiller products have the advantage over existing cartilage treatment options such as microfracture surgery, OCT (osteochondral transplant) surgery or ACT (autologous chondrocyte transplantation) in that they can be produced without…

Article - 05/05/2014

Michael Doser brings together biomedicine and textile research

Textile products used for the treatment of wounds are increasingly being coupled with bioactive functions. A growing number of biocompatible and absorbable high-tech materials are used on and in the human body for therapy, diagnosis and measurements. Michael Doser, Director of Medical Engineering/Biomedical Process Engineering at the ITV Denkendorf, is working on innovative wound management products and processes.

Article - 31/03/2014

Lsd1 – a gatekeeper for differentiation onset of embryonic mouse stem cells

Epigenetics is an emerging field of research that studies heritable changes in gene expression that are not caused by changes in the underlying DNA sequence. Prof. Dr. Roland Schüle, Director of Central Clinical Research at the Freiburg University Medical Centre, and his team are specifically focused on epigenetic modifiers that regulate the timely development of placental mouse tissue. Schüle and his team have discovered in mouse embryos that a…

Article - 03/03/2014

TETEC – the cartilage makers

What you need is patient cells. The certified laboratories of TETEC AG use autologous cells to produce biological cartilage replacement for degenerated joints and intervertebral discs. The company considers itself the global market leader in the knee cartilage market. This means that the rapidly growing company is excellently placed for introducing new products to the regenerative medicine market.

Article - 24/02/2014

Enhanced feeling of well-being triggers regeneration

New biomaterials are all the rage – especially in the Department of Oral Biotechnology, which was established at the Dental School and Hospital at the Freiburg University Medical Centre in 2008. The department’s laboratory manager, Prof. Dr. Thorsten Steinberg, takes an approach that is inspired by clinical application and aimed at developing biomaterials that support the wound healing process. This approach must, of necessity, include basic…

Article - 28/06/2013

A world champion of regeneration

Planarians can be cut into pieces, and each piece can regenerate into a complete organism. The flatworms are able to do this as they have a huge pool of adult totipotent stem cells that can differentiate into any body cell whatsoever, including germ cells. Scientists from the Heidelberg Institute for Theoretical Studies are using new algorithms to analyse the complex planarian genome structures with the aim of obtaining insights into the genetic…

Article - 11/02/2013

REGiNA – the health region for regenerative medicine

REGiNA is a users’ centre for regenerative medicine in the area bordered by the cities of Stuttgart and Tübingen and the Neckar-Alb region. It was established with the aim of translating a variety of advanced regenerative methods into broad clinical application. Providing a diverse and broad range of information, REGiNA is focused on making new treatment possibilities and the opportunities created by regenerative medicine known to doctors,…

Article - 31/12/2012

siRNA for the regeneration of tissue and nerves

Regenerative medicine is increasingly making use of siRNA to turn off proteins that prevent the application of regenerative therapies. Researchers at the NMI in Reutlingen develop siRNA technologies that have the potential to prevent the development of fibroses, the encapsulation of implants and improve the regeneration of nerves.

Article - 19/11/2012

Biopharm GmbH: growth factors for use in regenerative medicine

With more than 26 years’ experience in the field of orthopaedics, dermatology and personalised medicine, the Heidelberg-based biotechnology company Biopharm GmbH is firmly established in the regenerative medicine market. Based on its proprietary growth factor technology platform, Biopharm develops innovative methods for the treatment of bone and cartilage damage and improvement of the wound healing process.

Article - 19/11/2012

SYMBIOSIS - The Analytical Company

SYMBIOSIS, the new business unit of Heidelberg-based Biopharm GmbH, offers a wide range of analytical services, including tests, detection methods and methodological innovations related to the development of classical pharmaceuticals and biopharmaceuticals. SYMBIOSIS is a GMP- and GLP-certified provider of analytical services with long-standing experience and know-how that combines high-quality, state-of-the-art methods and solutions for its life…