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candidum GmbH

Who we are
candidum is a biotechnology spin-off associated with the University Stuttgart, Germany. We apply a proprietary bioinformatics toolset in combination with laboratory screening to design focused combinatorial enzyme libraries or to condense inhibitor panels. We deliver combinatorial libraries tailored to available screening capacities that cover comprehensive regions of sequence space and diverse evolutionary pathways. We are looking for partners to expand our tech- nology to inhibitor panel prescreening and the design of interfacial disruptors.

Our Exclusive Technology
We apply proprietary computational methods that combine accelerated molecular dynamics with unique methods of hotspot evaluation. With massive parallel computing, we achieve the precision of traditional molecular dynamics simulations, while maintaining statistical significance comparable to high-throughput methods such as molecular docking.

Benefits at a Glance
• Greatly reduced R&D costs
• Exceptional library quality
• Short development time
• Increase success rate
• Enable complex projects

candidum Enzyme Design
• Holistic analysis of enzyme-substrate interactions
• Full dynamics characterization by 1000+ simulations
• Mapping of biochemical function to hotspot areas
• Specific hotspot position profiles and ranking
• Comprehensive mutability and evolvability studies
• Full combinatorial diversity with highly focused library sizes

Biotech CompaniesBioinformatics, Proteins/Peptides, Biotech Services, Contract Research & Development, Industrial Biotech

Further information on the websites of BIOPRO Baden-Württemberg:

Website address: https://www.gesundheitsindustrie-bw.de/en/database/details