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  • Article - 03/03/2016 Schematic showing how liquid biopsies can be used to analyse freely circulating (fc) DNA in the blood. The schematic shows the technique as applied to GIST (gastrointestinal stroma tumours).

    Liquid biopsies – beacons of hope for cancer diagnosis?

    Researchers around the world, including researchers from the Freiburg University Medical Center, are working on developing simple blood tests, so-called liquid biopsies, that can be used to obtain accurate information about tumour staging and the progress of therapy. An international liquid biopsy symposium was held in Freiburg in October 2015 and has produced valuable insights.

    https://www.gesundheitsindustrie-bw.de/en/article/news/liquid-biopsies-beacons-of-hope-for-cancer-diagnosis
  • Article - 07/03/2016 Schematic representation of the methods: i) Structural data are generated by multiple methods, predominantly mass spectrometry, and are used alongside available data from databases. ii) The system is represented as a collection of rigid bodies and beads on a flexible string. iii) An ensemble of structures that are consistent with the experimental data is obtained by conformational sampling. iv) The ensemble is analysed and validated.

    Looking at the control of cellular homeostasis

    Many biological processes that occur in our body are driven and controlled by protein complexes. In order to better understand these processes, biochemist Prof. Dr. Florian Stengel from the University of Konstanz is developing methods that will eventually make it possible to study the architecture, interactions and general dynamics of intact protein complexes quantitatively and in detail. Stengel combines structural mass spectrometry methods with…

    https://www.gesundheitsindustrie-bw.de/en/article/news/looking-at-the-control-of-cellular-homeostasis
  • Article - 11/04/2016 Schematic representation of a big, blue, spherical virus.

    Glycovirology: carbohydrate molecules against infections

    Many viruses enter cells by way of carbohydrate molecules known as glycans to which they bind during the initial steps of infection. However, it is still largely unknown how glycan-mediated infection proceeds. This is about to change with a working group that has been set up by the DFG at the University of Tübingen and five other universities. The group will focus on glycovirology, a new scientific area that aims to understand the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/glycovirology-carbohydrate-molecules-against-infections
  • Article - 30/05/2016 The photo shows a next-generation sequencer consisting of a sequencing unit and a desktop computer.

    The unknown dark spot of the microcosm

    The world of microorganisms is still largely unknown. Researchers such as Kai Sohn from the Fraunhofer IGB in Stuttgart are working on decoding, analysing and gradually gaining a better understanding of the microbial genome. In their search for new enzymes and other biomolecules, both biotechnologists and pharmacologists are interested in micoorganisms, and physicians are hoping that detailed insights into the microbial genome will lead to the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-unknown-dark-spot-of-the-microcosm
  • Article - 17/05/2016 A tiny stent held between thumb and forefinger. The scaffold is many times smaller than a fingernail, is rectangular and consists of several interconnected shafts.

    Medical devices legislation: laborious compromises in Brussels

    The revision of the European legislation on medical devices is aimed at making medical devices safer and rebuilding the trust of patients. Rather than implementing the system change that was being planned after the silicone breast implant scandal in 2010, the EU called for open public consultation to prevent such incidents from occurring. As a result, revision of the legislation has been ongoing since autumn 2012.

    https://www.gesundheitsindustrie-bw.de/en/article/news/medical-devices-legislation-laborious-compromises-in-brussels
  • Article - 16/06/2016 The photo shows Prof. Dr. Peter Nick standing in front of a variety of plants.

    Microfluidic biofermenter mimics plant tissue

    It is estimated that as many as one million secondary plant metabolites can be used as medical agents. Plants produce these compounds to aid their growth and development as well as to discourage herbivores from eating them. However, it is still very difficult, or even impossible, to produce secondary plant metabolites industrially. Researchers from the Karlsruhe Institute of Technology (KIT) are now developing a microfluidic bioreactor to make…

    https://www.gesundheitsindustrie-bw.de/en/article/news/microfluidic-biofermenter-mimics-plant-tissue
  • Article - 20/06/2016 Photo showing a disk-shaped cartridge for use in a point-of-care system.

    New diagnostic tool for greater health safety when dealing with multidrug-resistant pathogens

    Infections with antibiotic-resistant bacteria and diseases such as breast or colon cancer are among the major causes of death worldwide. Early diagnosis is therefore key for the identification of people affected and for providing immediate therapy. The R&D service provider Hahn-Schickard and its partners are currently working on the development of a rapid and simple diagnostic system that can detect life-threatening infections and cancer at…

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-diagnostic-tool-for-greater-health-safety-when-dealing-with-multidrug-resistant-pathogens
  • Article - 30/06/2016 Fettfaerbung_in_der_Leber_HZ_Mchn.jpg

    Why fasting is good for health

    A protein in the nucleus of liver cells is produced in greater quantities when we go hungry; it limits fatty acid uptake and adjusts the metabolism in the liver. However in people with metabolic disorders, the abnormal expression of this protein (GADD45β), which was previously only known to be involved in the regulation of cell division and DNA repair, leads to a dysregulated fat and sugar metabolism. Scientists from the DKFZ and Helmholtz…

    https://www.gesundheitsindustrie-bw.de/en/article/news/why-fasting-is-good-for-health
  • Company profile - 18/07/2016 A tablet computer and a smartphone with a medical image.

    mbits imaging GmbH – mobile app in the field of radiology

    Trying to get a second opinion from a medical colleague who is at home preparing dinner may be quite a challenge, especially when the colleague does not have access to the necessary image data. This has now become easier in the field of radiology thanks to a mobile app called mRay, which provides a reliable way for radiologists to share medical images on mobile devices.

    https://www.gesundheitsindustrie-bw.de/en/article/news/mbits-imaging-gmbh-mobile-app-in-the-field-of-radiology
  • Company profile - 14/07/2016 Schematic showing how the neurostimulator leads to the stimulation of the vagus nerve lowers the blood pressure.

    neuroloop GmbH: how the manipulation of neuronal information can lower blood pressure

    Millions of people worldwide suffer from high blood pressure. However, taking medicines to control high blood pressure does not work for everyone. Dr. Dennis Plachta and Prof. Dr. Thomas Stieglitz from IMTEK have now developed a neurostimulator to control blood pressure. Together with Dr. Michael Lauk, an experienced company founder, the two researchers set up a company called neuroloop, which is funded by Aesculap AG and aims to turn the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/neuroloop-gmbh-how-the-manipulation-of-neuronal-information-can-lower-blood-pressure
  • Article - 19/07/2016 Symbolic 3D model with a T cell equipped with CAR and the relevant DNA.

    Licence to kill – the enormous potential of CAR T cells

    With 6 million euros of EU funding, the CARAT project aims to optimise a technology called CAR T that is used to equip T cells with antibody fragments and specifically direct them to destroy cancer cells. The CARAT consortium comprises a multinational team of experts from the Institute for Cell- and Gene Therapy at the Freiburg University Medical Center led by Prof. Dr. Toni Cathomen and seven partner institutions. Cathomen’s team is developing…

    https://www.gesundheitsindustrie-bw.de/en/article/news/licence-to-kill-the-enormous-potential-of-car-t-cells
  • Article - 21/07/2016 Photo of three hop cones.

    New anticancer drugs – hop compounds have the potential to treat cancer

    Secondary hop compounds appear to have a positive effect on the immune system and therefore have the potential to be used for the treatment and prevention of cancer. However, the bioavailability of hop compounds in the human body is relatively poor. Researchers from Hohenheim and Tübingen are therefore looking for a way to increase their absorption rate.

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-drugs-for-the-treatment-of-cancer-hop-compounds-have-the-potential-to-treat-cancer
  • Article - 27/07/2016 The left part of the schematic shows the phylogenetic tree of Ebola viruses. The different regions where the Ebola viruses were found are represented in different colours. The right side shows a map of West Africa; the regions where the viruses used for the analysis were found have the same colour as the respective lines in the tree.

    “Open science“ – a successful recipe for combating viruses

    Danger identified, danger averted – the better the dynamic changes of the viral genome are understood, the better the spread of the pathogens can be predicted, thus enabling more efficient countermeasures to be taken. A team of researchers from Tübingen and Seattle is developing an open source online platform that maps the evolution of viruses and identifies dangerous developments.

    https://www.gesundheitsindustrie-bw.de/en/article/news/open-science-a-successful-recipe-for-combating-viruses
  • Article - 08/09/2016 Computer image of gold molecules to which a diamondoid and a DNA molecule are bound.

    A diamond might make sequencing more accurate

    DNA sequencing techniques have been developed along the lines of faster, further, cheaper. State-of-the-art methods make it possible to handle large projects in a relatively short period of time. However, the error rate is still very high. Dr. Maria Fyta and her team at the Institute for Computational Physics at the University of Stuttgart have carried out quantum-transport calculations which suggested that specific chemical modifications in the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/a-diamond-might-make-sequencing-more-accurate
  • Article - 26/09/2016 Proteinkinasen.jpg

    TuCADD: Coaching for early drug candidates

    The University of Tübingen is optimising its drug development pipeline. The TuCADD consortium provides professional help to people who want to take potential drug candidates to clinical application. The coaching involves assistance with the entire phase I drug development phase from industry experts.

    https://www.gesundheitsindustrie-bw.de/en/article/news/tucadd-coaching-for-early-drug-candidates
  • Diagnosis - 13/02/2017 Tomes GmbH team at the Elevator Pitch BW in Freiburg.

    Idana: an anamnesis software that asks the right questions

    Studies have shown that communication between doctors and patients is very important for doctors to be able to give a precise diagnosis and to increase patient acceptance of therapy. Unfortunately, doctors often do not have the time for in-depth conversations with their patients. A new anamnesis software called Idana looks set to change this situation. The software tailors questions specifically to individual patients and helps treating doctors…

    https://www.gesundheitsindustrie-bw.de/en/article/news/idana-an-anamnesis-software-that-asks-the-right-questions
  • Article - 22/02/2017 Woman wearing a lab coat in front of a laboratory device. The photo shows the back of the woman.

    MammaScreen – blood test for early detection of breast cancer

    The MammaScreen team from the University of Heidelberg Women’s Hospital has developed a blood test for diagnosing breast cancer. This new test can detect breast cancer at a very early stage. It works on women of all ages with tumours of any type and size.

    https://www.gesundheitsindustrie-bw.de/en/article/news/mammascreen-blood-test-for-early-detection-of-breast-cancer
  • 24.04.2017

    World Day for Laboratory Animals

    On 24 April 2017 is "World Day for Laboratory Animals" – the BIOPRO provides information about this topic. In Baden-Württemberg alone, up to 600,000 animals are used for scientific purposes every year. In order to reduce their pain and suffering as much as possible, researchers all over the world are working on the development of innovative methods to replace animal experiments, including cell culture methods for drug analysis,…

    https://www.gesundheitsindustrie-bw.de/en/article/news/world-day-for-laboratory-animals
  • 24 - 30 April 2017

    European Immunization Week

    From 24 till 30 April 2017 is "European Immunization Week" – the BIOPRO provides information about this topic. Influenza pandemics are dangerous and can claim many lives. Children and the elderly in particular run a high risk of developing influenza-related complications, because their immune system is often weakened by the virus. In Germany, annual vaccination against seasonal influenza has therefore been recommended for these target…

    https://www.gesundheitsindustrie-bw.de/en/article/news/european-immunization-week
  • Overview

    World Days

    The "World Days" serve to recall international issues and current world problems. BIOPRO takes the "World Days" in the field of healthcare industry as an occasion to inform about this topic.

    https://www.gesundheitsindustrie-bw.de/en/article/news/world-days
  • Article - 18/05/2017 The photo shows a pipette with which drinking water is applied to the ImmuStick.

    ImmuStick – novel rapid test for identifying disease pathogens

    In some situations such as in the food and pharmaceutical industries or hospitals, a test to identify disease pathogens can be vital. At present, such tests are relatively time-consuming and can take hours or even days to produce results, depending on the pathogen. Scientists from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart are currently developing a rapid test called ImmuStick which is as easy to use…

    https://www.gesundheitsindustrie-bw.de/en/article/news/immustick-novel-rapid-test-for-identifying-disease-pathogens
  • Article - 07/06/2017 The fruit fly Drosophila is used as obesity model. The fat tissue has been visualised by way of GFP (green fluorescent protein) expression.

    A gene that regulates body heat and fat storage

    Researchers from Heidelberg have shown that the organismal balance between heat production and energy storage is regulated by a gene called THADA. In animal experiments, knocking out the THADA gene leads to excessive food intake, obesity and sensitivity to cold. As humans spread throughout the world and settled in different climate zones, THADA was exposed to high selection pressure due to evolutionary adaptation. This explains why human…

    https://www.gesundheitsindustrie-bw.de/en/article/news/a-gene-that-regulates-body-heat-and-fat-storage
  • Article - 12/06/2017 Photo shows of man (left) being withdrawn blood. The blood flows through a tube from the cannula to the blood collection tube.

    IHO: global consulting for the molecular diagnosis of leukaemia

    IHO GmbH from Mannheim offers a professional solution for the international exchange of information and services concerning the molecular diagnosis of leukaemia. This drives forward the harmonisation of these methods and brings therapy monitoring to a new global level.

    https://www.gesundheitsindustrie-bw.de/en/article/news/iho-global-consulting-for-the-molecular-diagnosis-of-leukaemia
  • Article - 14/08/2017 The two company founders in the laboratory holding reaction vessels.

    Saskia Biskup – towards precision medicine

    Therapeutic success can only be achieved when diagnoses are as precise as possible. Nowadays, genetic analyses can make precise diagnoses for many diseases. And thanks to high-throughput technology, results are available to patients very quickly. Dr. Dr. Saskia Biskup recognised the importance of precision medicine many years ago and went on to found CeGaT GmbH, a company that combines human genetics with high-throughput sequencing. Three…

    https://www.gesundheitsindustrie-bw.de/en/article/news/saskia-biskup-towards-precision-medicine
  • Article - 15/01/2018 Schematic showing how a blockchain works.

    Blockchain technology as an opportunity for more transparency and self-determination

    In the healthcare sector, blockchain technology is still in the early stages of development, although it has huge potential in this field. It is expected that patients will particularly benefit from the introduction of a decentralised database for managing and sharing health-related information with treating physicians. Statutory health insurance companies become less important as intermediaries. But how exactly does this technology work?

    https://www.gesundheitsindustrie-bw.de/en/article/news/blockchain-technology-as-an-opportunity-for-more-transparency-and-self-determination

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