Press release - 17/05/2021 New findings in genome research The working group around Dr. Philipp Rathert at the Institute for Biochemistry and Technical Biochemistry investigates the regulation of epigenetic networks of certain cancers and ways of treating them. The working group published its new findings in April. https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-findings-genome-research
Article - 14/01/2021 Newly discovered RNA as growth driver in liver cancer Non-coding RNA (ncRNAs) molecules that do not encode proteins have many different functions, and some are associated with certain diseases. Prof. Dr. Sven Diederichs from the German Consortium for Translational Cancer Research and the German Cancer Research Center in Heidelberg has been conducting research into these molecules at the Freiburg University Medical Centre and discovered a ncRNA that regulates cell proliferation in cancer cells.https://www.gesundheitsindustrie-bw.de/en/article/news/newly-discovered-rna-growth-driver-liver-cancer
Researcher profile - 09/11/2015 Michael Boutros – from the study of social gene networks to the management of the DKFZ Deregulation of cell signalling pathways is a major driver of cancer. Prof. Dr. Michael Boutros has pioneered the development of new methods for the analysis of genetic interactions in such complex networks. He has been acting Chairman and Scientific Member of the Management Board of the German Cancer Research Center (DKFZ) since September 1st 2015. https://www.gesundheitsindustrie-bw.de/en/article/news/michael-boutros-from-the-study-of-social-gene-networks-to-the-management-of-the-dkfz
Dossier - 09/02/2015 Chemical tools for biological applications The boundaries between traditional scientific disciplines are becoming less and less distinct. Interdisciplinary cooperation is often required to study complex processes and biomolecular issues. Interdisciplinary cooperation is central to chemical biology, a scientific discipline that applies chemical substances, methods and tools to the study of biological systems ranging from the chemical synthesis of biologically active substances to the…https://www.gesundheitsindustrie-bw.de/en/article/dossier/chemical-tools-for-biological-applications
Dossier - 02/12/2013 RNA interference: confidence is returning The 15-year history of RNA interference is not short on dramatic effects. It begins with the unexpected discovery and publication of the process of post-transcriptional gene silencing in 1998 for which the two Americans Andrew Fire and Craig Mello were awarded the Nobel Prize in Physiology or Medicine just eight years after their discovery. In 2001 Thomas Tuschl succeeded in switching off genes in human cells with small synthetic pieces of RNA…https://www.gesundheitsindustrie-bw.de/en/article/dossier/rna-interference-confidence-is-returning
Article - 18/03/2013 Identification of genes that play a crucial role in regulating cholesterol levels Genome-wide association studies (GWAS), which were combined with RNA interference studies and microscope-based functional analyses, enabled researchers from the European Molecular Biology Laboratory and Heidelberg University Hospital to identify genes that play key roles in the regulation of the blood cholesterol level. The new method leads to a better understanding of the relationships between the lipid metabolism and the development of…https://www.gesundheitsindustrie-bw.de/en/article/news/identification-of-genes-that-play-a-crucial-role-in-regulating-cholesterol-levels
Article - 05/06/2012 Max Planck Director Izaurralde honored for groundbreaking research Professor Dr. Elisa Izaurralde has made important contributions to the field of RNA biology in recent years. The managing director of the Max Planck Institute for Developmental Biology in Tübingen explores the complex mechanisms of cellular gene regulation. For her work on mRNA regulation she has now been honored with the prestigious Ernst Jung Prize for Medicine.https://www.gesundheitsindustrie-bw.de/en/article/news/max-planck-director-izaurralde-honored-for-groundbreaking-research
Article - 23/04/2012 Vascular grafts: biomolecules to prevent blood vessels from reclosing Obstructed blood vessels can be operated on and adequate blood flow restored. However, stents and bypasses are often subject to high reclosure rates. Excessive immune reactions close to where the intervention took place might prevent the regeneration of adjacent vessel walls and even lead to reclosure. New interventions involving RNA interference seem to be a way out of this dilemma.https://www.gesundheitsindustrie-bw.de/en/article/news/vascular-grafts-biomolecules-to-prevent-blood-vessels-from-reclosing
Article - 29/08/2011 Ute Schepers – the therapeutic potential of small RNAs and molecular transporters Small RNAs can specifically interfere with cellular mechanisms; or more precisely, with the cells’ protein biosynthesis machinery. Scientists have therefore decided to exploit this potential by using small RNAs against cancer cells or cells damaged in other ways. But the question arises as to how the small RNAs can reach the site where their role is to prevent the generation of dangerous proteins. Dr. Ute Schepers and her team from the Karlsruhe…https://www.gesundheitsindustrie-bw.de/en/article/news/ute-schepers-the-therapeutic-potential-of-small-rnas-and-molecular-transporters
Article - 25/07/2011 Christian Thoma – the control of translation enables the rapid regulation of cellular processes Heisenberg fellow PD Dr. Christian Thoma from the Freiburg University Medical Centre has been focusing on the regulation of translation for a number of years and has established a method that enables him to investigate translation on the molecular level. Thoma and his team have come a step closer to their goal of finding targets for the therapy of cancer and hepatitis C.https://www.gesundheitsindustrie-bw.de/en/article/news/christian-thoma-the-control-of-translation-enables-the-rapid-regulation-of-cellular-processes
Press release - 08/06/2011 TagCyx Biotechnologies TagCyx is a research based company located in Yokohama Kanagawa Prefecture. The core technologies of TagCyx are unnatural base pair technologies and nucleic acids stabilization technology.https://www.gesundheitsindustrie-bw.de/en/article/press-release/tagcyx-biotechnologies
Article - 30/04/2011 The DKFZ-ZMBH Alliance The strategic alliance between the cell and tumour biology research priority at the German Cancer Research Center and the Center for Molecular Biology at Universität Heidelberg has led to the development of one of the largest centres of basic biomedical research in Germany. The top international profile of this interdisciplinary institution located at the interface between molecular and cellular biology tumour biology and biomedicine is reflected…https://www.gesundheitsindustrie-bw.de/en/article/news/the-dkfz-zmbh-alliance
Press release - 23/06/2010 Technology park „bioBAY“ - life science infrastructure the Chinese way Being one of Baden-Württemberg’s global partner regions, the Chinese province of Jiangsu deserves special attention in the field of life sciences. The highly dynamic bioBAY park located in the city of Suzhou puts a strong emphasis on bio- and nanotechnologies. With its numerous science and business opportunities bioBAY has a lot to offer also to potential partners from Baden-Württemberg. https://www.gesundheitsindustrie-bw.de/en/article/press-release/technology-park-biobay-life-science-infrastructure-the-chinese-way
Press release - 05/06/2010 No rest for cancer cells A research team led by scientists from the German Cancer Research Centre worked out that cancer cells rely on the tension of specific protein fibres to be able to multiply. Proteins that maintain this tension have now become promising targets for new target-specific anticancer drugs If these proteins are switched off cancer cells die.https://www.gesundheitsindustrie-bw.de/en/article/press-release/no-rest-for-cancer-cells
Article - 26/04/2010 PACT Pharmaceuticals – signalling pathways and RNA interference In March 2010 PACT Pharmaceuticals the founding concept of Professor Dr. Michael Boutros team at the German Cancer Research Centre was selected as one of ten outstanding business concepts in the Science4Life business plan competition intermediary award. Around 200 business plans were originally submitted. PACT develops innovative cancer therapeutics that target the signalling pathways involved in tumour pathogenesis. PACT develops innovative…https://www.gesundheitsindustrie-bw.de/en/article/news/pact-pharmaceuticals-signalling-pathways-and-rna-interference
Article - 14/11/2009 "A little naivety always helps" The biotech company CureVac based in Tuebingen is working on the development of a new tumour therapy based on RNA molecules. Dr. Ingmar Hoerr one of the scientists who founded CureVac tells Christoph Bächtle about the obstacles the young company had to overcome and the tough decisions that led to success. At the very start he tells us the company owes its origins to a huge dollop of luck.https://www.gesundheitsindustrie-bw.de/en/article/news/a-little-naivety-always-helps
Article - 12/08/2009 More effective extraction of small RNAs Small RNAs are gaining in importance in research as well as in the biotechnology and pharmaceutical industries. However the potential of these molecules can only be exploited fully if very pure RNAs can be extracted from the cells in sufficiently high quantities. Currently used methods are expensive and only designed for large cell quantities. In addition the operation of the extraction systems is very complicated. A new biochip developed by Dr.…https://www.gesundheitsindustrie-bw.de/en/article/news/more-effective-extraction-of-small-rnas
Press release - 05/09/2008 Thomas U. Mayer - research for aesthetes Mayers major interest is cell division which he sees as an interesting and also a beautiful aesthetic process. Prof. Dr. Thomas U. Mayer occupies the chair of molecular genetics at the University of Constance where he enjoys working in close contact with colleagues from the field of chemistry.https://www.gesundheitsindustrie-bw.de/en/article/press-release/thomas-u-mayer-research-for-aesthetes
Article - 17/07/2008 Communication platform for researchers SciLife is a new virtual presentation and communication platform for the scientific community. The platform is now also available free of charge to researchers who want to increase networking activities and who are looking for equipment and researchers.https://www.gesundheitsindustrie-bw.de/en/article/news/communication-platform-for-researchers
Article - 15/07/2008 Simple explanations are not enough - assessment and criticism are a must What is the difference between knowledge and science? Why did the biotech bubble develop in the first place? Find out more as we talk to the freelance science journalist Sascha Karberg.https://www.gesundheitsindustrie-bw.de/en/article/news/simple-explanations-are-not-enough-assessment-and-criticism-are-a-must