Article - 15/07/2008 Simple explanations are not enough - assessment and criticism are a must What is the difference between knowledge and science? Why did the biotech bubble develop in the first place? Find out more as we talk to the freelance science journalist Sascha Karberg.https://www.gesundheitsindustrie-bw.de/en/article/news/simple-explanations-are-not-enough-assessment-and-criticism-are-a-must
Press release - 04/01/2018 CureVac and Arcturus Therapeutics Announce Broad Strategic Collaboration to Advance Next Generation of Lipid-Mediated mRNA Therapeutics CureVac AG, a leading clinical-stage biopharmaceutical company focused on the development of pioneering mRNA therapeutics, and Arcturus Therapeutics Ltd. (NASDAQ:ARCT), an RNA medicines company, today announced they have entered into a broad strategic collaboration to jointly discover, develop and commercialize novel messenger RNA (mRNA) therapeutics.https://www.gesundheitsindustrie-bw.de/en/article/press-release/curevac-and-arcturus-therapeutics-announce-broad-strategic-collaboration-to-advance-next-generation-of-lipid-mediated-mrna-thera
Article - 09/02/2008 A better alternative from the perspective of embryo protection Karin Bundschuh of BIOPRO Baden-Württemberg asked Dr. Jens Clausen how these developments should be viewed from an ethical perspective. The bioethicist spent many years studying the status of embryos the ethics of cloning and stem cell research.https://www.gesundheitsindustrie-bw.de/en/article/news/a-better-alternative-from-the-perspective-of-embryo-protection
Article - 27/08/2012 Cardiac or intestinal progenitor cells? What controls the fate of pluripotent stem cells? Cell fate decisions are made in the early mouse embryo when it is nothing more than a spherical mass of cells. A molecule known as eomesodermin determines whether pluripotent stem cells become cardiac or intestinal progenitor cells. Dr. Sebastian Arnold and his research group at the Freiburg University Medical Centre have recently discovered why one single molecule can have a twofold effect. These findings provide Arnold and his team with greater…https://www.gesundheitsindustrie-bw.de/en/article/news/cardiac-or-intestinal-progenitor-cells-what-controls-the-fate-of-pluripotent-stem-cells
Article - 31/03/2008 "Nanomedicine will be able to combat incurable diseases" The first European Conference for Clinical Nanomedicine is to be held soon in Basel. BIOPRO has therefore discussed this promising area of application with Beat Löffler and Dr. Patrick Hunziker the founders of the European Foundation for Clinical Nanomedicine.https://www.gesundheitsindustrie-bw.de/en/article/news/nanomedicine-will-be-able-to-combat-incurable-diseases
Article - 29/11/2008 The worm in humans Caenorhabditis elegans has a lifespan of 20 days. The worm is as small as a comma and consists of only 959 cells. Caenorhabditis elegans is very different from Homo sapiens who might at least in Germany live for as long as 79 years or more. Nevertheless the tiny worm is the most important model organism for researchers into ageing who use it to study the development of age-related diseases and the ageing process itself.https://www.gesundheitsindustrie-bw.de/en/article/news/the-worm-in-humans
Development of the genomDE genome database - 04/12/2020 Whole genome sequencing for diagnosing rare diseases Grouped together, rare diseases are by no means a rare phenomenon; however, they are rarely correctly diagnosed and rarely properly treated. In most cases, there is no effective medication available. Rare disease centres staffed by experts have been set up in many German cities to speed up the often long and painful search for the right diagnosis and treatment. Whole genome sequencing is a component of general healthcare, used to identify…https://www.gesundheitsindustrie-bw.de/en/article/news/whole-genome-sequencing-diagnosing-rare-diseases
Article - 28/02/2011 The regulation of the intestinal immune system If the interplay of factors that regulate the intestinal immune system tips out of balance, this could result in allergic reactions or serious inflammatory intestinal diseases. Professor Dr. med. Stefan Meuer, Managing Director of the Institute for Immunology at the University Hospital in Heidelberg, is focusing on the molecular mechanisms of mucosal immune regulation. https://www.gesundheitsindustrie-bw.de/en/article/news/the-regulation-of-the-intestinal-immune-system
Article - 29/05/2012 Isabelle Seemann: DNA as building block for nanostructures Since the emergence of nanotechnology in the 1980s DNA has been used as a construction material in many areas. Wires grids and nanorobots can all be produced from this versatile material. Isabelle Seemann scientist at the University of Konstanz works with a particular DNA constellation known as three-way DNA junction. Seemanns findings are of great importance for different areas of knowledge including the material sciences analytics and…https://www.gesundheitsindustrie-bw.de/en/article/news/isabelle-seemann-dna-as-building-block-for-nanostructures
Article - 23/05/2011 Alzheimer’s disease puzzle remains unsolved despite new findings and theories 105 years after the first description of the Alzheimers disease by the German neuropsychiatrist Alois Alzheimer the disease still remains a mystery. Around 25000 researchers worldwide are focusing on Alzheimers and are coming up with a broad range of theories and hypotheses on its pathogenesis and potential therapies.https://www.gesundheitsindustrie-bw.de/en/article/news/alzheimer-s-disease-puzzle-remains-unsolved-despite-new-findings-and-theories
Article - 10/09/2009 Cadherins – keeping cells together is not their only purpose If they are absent everything goes wrong. Right from the development of the embryo the cell adhesion molecules of the cadherin superfamily ensure that cells are bound together while they are developing and when they become adult organisms. Cadherins fix tissue in place and give it shape and identity. But this is far from being all that they do. Dr. Dirk Junghans and his team at the Freiburg University Medical Centre have carried out experiments…https://www.gesundheitsindustrie-bw.de/en/article/news/cadherins-keeping-cells-together-is-not-their-only-purpose
Article - 06/07/2015 Blood stem cells deliver drugs to brain tumours The brain is the central switchboard in our body. Professor Ghazaleh Tabatabai’s work focuses specifically on the brain and the fight against uncontrolled proliferation of brain tumours. In May 2014, she was appointed professor in the newly established Interdisciplinary Division of Neuro-Oncology at the University of Tübingen and head of the Clinical and Experimental Neuro-Oncology research group at the Hertie Institute for Clinical Brain…https://www.gesundheitsindustrie-bw.de/en/article/news/blood-stem-cells-deliver-drugs-to-brain-tumours
Article - 13/02/2012 A strange combination: green tea extract and light for treating Alzheimer’s Andrei Sommer from the University of Ulm and colleagues from Ulm, Heidelberg and Berlin have succeeded in reducing amyloid beta deposits in human neuroblastoma cells by up to 60 per cent in vitro. The researchers found that the apparently strange combination of green tea and red light has the potential to lead to the development of new therapies for Alzheimer’s. There are currently no treatments available that stop or reverse the progression of…https://www.gesundheitsindustrie-bw.de/en/article/news/a-strange-combination-green-tea-extract-and-light-for-treating-alzheimer-s
Article - 08/09/2008 Research increases hope Duchenne muscular dystrophy DMD is a severe disease affecting boys characterised by rapid progression of muscle degeneration so that boys as young as 10 to 12 years of age have to use a wheelchair and leading to death in young men. In Germany about 2500 children and young adults suffer from DMD.https://www.gesundheitsindustrie-bw.de/en/article/news/research-increases-hope
Article - 30/11/2009 The problem children of protein biochemistry A large number of cellular proteins are located in or on a membrane. Dr. Dirk Schneider from the University of Freiburg believes that biochemists who investigate such proteins must be a little crazy, as the methods required to isolate the molecules from their exotic environment, i.e. from the lipid bilayer, are extremely difficult and complicated. Research has long focused on water-soluble proteins. Schneider and his team have now taken on the…https://www.gesundheitsindustrie-bw.de/en/article/news/the-problem-children-of-protein-biochemistry
Dossier - 01/10/2012 Systems biology: understanding complex biological systems Systems biology studies complex interactions within biological systems on the genome proteome and organelle level. Many techniques from the fields of systems theory and associated fields can be used to gain an understanding of the behaviour and biological mechanisms of cellular systems.https://www.gesundheitsindustrie-bw.de/en/article/dossier/systems-biology-understanding-complex-biological-systems
Press release - 27/09/2018 One hundred percent success Two Clusters of Excellence for the University of Freiburg: Biological Signalling Studies and Bioinspired Materials Research. It is a major boost to cutting-edge research in Freiburg: in the current Excellence Strategy competition, scientists at the University of Freiburg have been granted two Clusters of Excellence, CIBSS – Centre for Integrative Biological Signalling Studies, and livMatS – Living, Adaptive and Energy-autonomous Materials…https://www.gesundheitsindustrie-bw.de/en/article/press-release/one-hundred-percent-success
Article - 02/05/2016 Hepatitis C: a new starting point for vaccine development With approximately 150,000 infected people in Germany, hepatitis C is a common disease for which therapies, but no vaccine, are available. Dr. Tobias Böttler from the Freiburg University Medical Center and his team are exploring the body’s immune response to the hepatitis C virus (HCV) and have found valuable information that could be used for vaccine development.https://www.gesundheitsindustrie-bw.de/en/article/news/hepatitis-c-a-new-starting-point-for-vaccine-development
Article - 27/08/2012 How the distance from the source affects tissue patterning and growth in embryos During the embryonic development of fruit flies, zebra fish and humans, just a handful of molecules control cell migration, induce cell division and determine which cells form which type of tissue. A group of researchers led by Dr. Giorgos Pyrowolakis at the University of Freiburg is specifically focused on one of these so-called master regulators. How do the differently patterned BMP gradients develop in Drosophila melanogaster eggs, embryos and…https://www.gesundheitsindustrie-bw.de/en/article/news/how-the-distance-from-the-source-affects-tissue-patterning-and-growth-in-embryos
Article - 09/10/2019 Epigenomics from the Cyber Valley Cyber Valley Stuttgart-Tübingen is a European hotspot for artificial intelligence and home to many renowned experts and scientists. They are now joined by Gabriele Schweikert, who heads up the Computational Epigenomics research group in the Cyber Valley’s Division of Computational Biology. Schweikert is interested in exploring epigenetic mechanisms using machine learning methods.https://www.gesundheitsindustrie-bw.de/en/article/news/epigenomik-aus-dem-cyber-valley
Article - 02/07/2009 A virus that hides while it waits for an opportunity to replicate Thomas Mertens, Medical Director of the Institute of Virology in Ulm, has a strong scientific and clinical interest in the human cytomegalovirus (HCMV), a big virus with a big impact which, despite its size, is overshadowed by known viruses such as the HI virus that is the object of research for Mertens’ colleagues. HCMV research is a challenging area where quick successes are rare.https://www.gesundheitsindustrie-bw.de/en/article/news/a-virus-that-hides-while-it-waits-for-an-opportunity-to-replicate
Dossier - 07/02/2011 The era of personalised medicine is dawning A promising future does not easily disappear into thin air. This is certainly the case with the vision of personalised medicine. For many years, biomedical researchers have vaunted the potential benefits of their findings despite the fact that neutral observers do not think that personalised medicine will really take off within the next 15 or 20 years. Moreover personalised medicine is a controversial term. So what is the state of play right now?https://www.gesundheitsindustrie-bw.de/en/article/dossier/the-era-of-personalised-medicine-is-dawning
Article - 24/10/2008 The game needs to be discovered Prof. Dr. Michael Reth is active in the field of immunology and signalling. He is an experienced scientist who is well aware of the difficulty and the cumbersome nature of deciphering signals and signalling pathways. The Freiburg bioss excellence cluster - the Centre of Biological Signalling Studies - is Reths brainchild. Karin Bundschuh from BioRegio Freiburg spoke with the scientist who works at the Max Planck Institute of Immunobiology and the…https://www.gesundheitsindustrie-bw.de/en/article/news/the-game-needs-to-be-discovered
Article - 12/06/2017 IHO: global consulting for the molecular diagnosis of leukaemia IHO GmbH from Mannheim offers a professional solution for the international exchange of information and services concerning the molecular diagnosis of leukaemia. This drives forward the harmonisation of these methods and brings therapy monitoring to a new global level.https://www.gesundheitsindustrie-bw.de/en/article/news/iho-global-consulting-for-the-molecular-diagnosis-of-leukaemia
Article - 18/08/2008 Vitamin D reduces mortality risk The medical importance of vitamin D calciferol is most likely even higher than suggested by recently published studies. A study which also involves the endocrinologist Bernhard Böhm from Ulm has attracted enormous attention as it suggests that vitamin D deficiency increases mortality.https://www.gesundheitsindustrie-bw.de/en/article/news/vitamin-d-reduces-mortality-risk