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  • Cluster of the future - 25/11/2021 NanodiagBW_Teaser.png

    nanodiagBW: using nanopores to create completely new diagnostic possibilities

    Modern medicine has a wide range of molecular diagnostics at hand. In the next decade, this will increasingly be supplemented by prognostic methods. The BMBF Cluster of the Future finalist, nanodiag BW, is developing prognostic methods to identify epigenetic factors for diseases through a new type of bioanalytics – single molecule analysis in nanopores – which would make it possible to take personalised prevention approaches.

    https://www.gesundheitsindustrie-bw.de/en/article/news/nanodiagbw-using-nanopores-create-completely-new-diagnostic-possibilities
  • Press release - 18/11/2021

    Overcoming resistance to treatment for breast, bowel, and pancreatic cancer

    As cancer progresses, the tumor cells continually change, ultimately resulting in a tumor consisting of a large number of different cell clones with different characteristics. This is referred to as "tumor heterogeneity". In many cases, the cancer cells become resistant to the treatments available.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/overcoming-resistance-treatment-breast-bowel-and-pancreatic-cancer
  • Press release - 18/11/2021

    Overcoming resistance to cancer treatment: bone and soft tissue tumors in adolescents as a model system

    Treatment resistance is a central problem in the treatment of cancer. Bone and soft tissue tumors – known as sarcomas – in adolescents and young adults often stop responding to treatment too. This is because cancer cells develop a large number of new characteristics as the disease progresses and often become resistant to drugs that were originally effective.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/overcoming-resistance-cancer-treatment-bone-and-soft-tissue-tumors-adolescents-model-system
  • Microfluidic systems - 18/11/2021 Hand holding a round plastic disk with numerous channels and chambers.

    Dermagnostix develops molecular diagnostic tests for skin diseases

    Dermagnostix GmbH has developed a rapid test to differentiate between psoriasis and eczema. This test is currently undergoing preclinical testing, with market launch planned for 2023. The start-up is already working on two other dermatological tests. Centrifugal microfluidics is the name of the technology on which the tests are based.

    https://www.gesundheitsindustrie-bw.de/en/article/news/dermagnostix-develops-molecular-diagnostic-tests-skin-diseases
  • Press release - 18/10/2021

    More precise characterization of brain tumors improves diagnosis and therapy

    An international study with about 3000 patients confirms the validity of a new classification system for meningiomas. It combines tissue characteristics (histology) with molecular analyses and thus improves therapy planning.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/more-precise-characterization-brain-tumors-improves-diagnosis-and-therapy
  • Optimised peptides against infections and cancer - 07/10/2021 Zu sehen ist in einem Schema, wie bioaktive Peptide aus dem Körper entnommen, verbessert und wieder in den Körper gelangen.

    New bioactive ingredients from the peptidome treasure chest

    Peptides are increasingly coming into scientific focus for application in diagnostics and therapy. The human body is full of these protein fragments, but only a fraction have been characterised. So there is enormous potential for discovering new biologically active substances that can help in the fight against bacteria, viruses and cancer. A collaborative research centre at Ulm University Hospital is on the trail of these promising fragments.

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-bioactive-ingredients-peptidome-treasure-chest
  • Neurodegenerative diseases - 30/09/2021 A computer screen with MRI images of the head, in front of which is a doctor's hand showing her patient the values on a tablet.

    Artificial intelligence enables early diagnosis of dementia

    We are all afraid of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Yet, therapies are increasingly becoming available. Although they do not cure what causes a disease, they can at least slow down its progression, provided it is diagnosed as early as possible. The Tübingen-based start-up AIRAmed has developed software that uses artificial intelligence to measure and detect changes in the brain long before they…

    https://www.gesundheitsindustrie-bw.de/en/article/news/artificial-intelligence-enables-early-diagnosis-dementia
  • Personalised medicine - 16/09/2021 Diagram illustrating pharmacogenomics. Individuals with different genetic makeups are shown as different coloured pictograms and have different combinations of efficacy and toxicity. A drawing of an hourglass is used to illustrate the influence of non-genetic factors.

    Pharmacogenomics enables individualised drug prescription

    Every person is unique, and their reaction to medications can be just as individual. For this reason, unexpected side effects occur time and again with common drugs, sometimes with life-threatening consequences. At the Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology (IKP) in Stuttgart, the influence of hereditary factors on these harmful reactions is being investigated in order to enable individualised therapies.

    https://www.gesundheitsindustrie-bw.de/en/article/news/pharmacogenomics-enables-individualised-drug-prescription
  • Press release - 16/07/2021

    Corona test with cotton swab

    To diagnose an infection with the coronavirus, usually a throat swab is taken and genetic viral material detected by using a highly sensitive PCR. To date, more than 65 million of these tests have been performed in Germany alone. Due to the massive increase in testing worldwide and simultaneous loss of production, there was a significant shortage of test materials in the early stage of the pandemic.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/corona-test-cotton-swab
  • Press release - 26/05/2021

    Memetis continues its path to become a technology leader in Shape Memory driven miniature valving – Fluid-o-Tech S.r.l. invests an undisclosed amount to support memetis’ growth and development

    The Deep-Tech Start-Up memetis GmbH from Germany, which produces the world’s most compact and lightest commercially available valves driven by shape memory alloys, announces a new partnership with Fluid-o-Tech S.r.l., an Italian innovation and market leader in the field of fluid-pumps.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/memetis-continues-its-path-become-technology-leader-shape-memory-driven-miniature-valving-fluid-o-tech-srl-invests-undisclosed-a
  • Press release - 17/05/2021

    New findings in genome research

    The working group around Dr. Philipp Rathert at the Institute for Biochemistry and Technical Biochemistry investigates the regulation of epigenetic networks of certain cancers and ways of treating them. The working group published its new findings in April.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-findings-genome-research
  • Microfluidics in medical technology - 24/03/2021 Ein Ventil-Modell, das auf einem Block mit elektrischem Anschluss verschweißt ist

    Ultra-compact: valves with shape memory actuators

    Karlsruhe-based company memetis shows that this is possible. Intelligent components for controlling fluids open up huge potential in the medical technology and biotechnology sectors - from vaccine development and cell line analysis to drug research and point-of-care solutions.

    https://www.gesundheitsindustrie-bw.de/en/article/news/ultra-compact-valves-shape-memory-actuators
  • Press release - 19/03/2021

    New single-cell analysis of leucemic stem cells

    A new method allows stem cells and cancer stem cells to be studied at the single cell level and the resulting cell clones to be traced directly. Studying thousands of individual cells in parallel, the researchers combined the analysis of the genomic cancer mutations with the associated expression profiles.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-single-cell-analysis-leucemic-stem-cells
  • Article - 17/03/2021 Schematische Abbildung des Tetracyclin-induzierbaren epigenetischen Gedächtnissystems in einem Escherichia coli Bakterium.

    Epigenetic switches in bacteria as biosensors

    The analysis of pathogen biomarkers and biomarkers for the diagnosis of diseases can be crucial for health. However, the detection of pathogens and diseases depends on a sensitive and reliable method that delivers rapid results. Biosensors have such properties. Researchers at the Institute of Biochemistry and Technical Biochemistry (IBTB) at Stuttgart University have constructed an epigenetic circuit composed of plasmids that might make it…

    https://www.gesundheitsindustrie-bw.de/en/article/news/epigenetic-switches-bacteria-biosensors
  • Press release - 11/03/2021

    Researchers recommend earlier start of breast cancer screening with family history of ovarian cancer

    Women have an increased risk of breast cancer if they have a family history of this disease. However, the risk may also be higher if first-degree family members have another type of cancer, according to a study by a team of scientists and physicians from the National Center for Tumor Diseases (NCT) Heidelberg, the German Cancer Research Center (DKFZ) and Heidelberg University Hospital (UKHD), as well as international colleagues.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/researchers-recommend-earlier-start-breast-cancer-screening-family-history-ovarian-cancer
  • Article - 10/03/2021 Bild2-Mahlwerk.jpg

    Faster to single cells using miniature grinder

    Tissue cells are needed for medical diagnostics, cell therapies and tissue engineering, among other things. A novel tissue grinder gently and automatically dissociates cells from tissue. In November 2020, the newly founded biotech company Fast Forward Discoveries GmbH (FFX) delivered its first tissue grinders to customers.

    https://www.gesundheitsindustrie-bw.de/en/article/news/faster-single-cells-using-miniature-grinder
  • Press release - 24/02/2021

    Supposedly "silent" mutation with serious consequences

    So-called silent mutations have no effect on the composition of a protein. They are therefore not considered to promote cancer. However, scientists from the German Consortium for Translational Cancer Research (DKTK), partner site Essen, now describe in a case of kidney cancer an overlooked silent mutation with a major impact on prognosis.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/supposedly-silent-mutation-serious-consequences
  • Article - 17/02/2021 Messerer_Bild_2.jpg

    Whole blood model enables development of early warning system for sepsis

    Sepsis is a life-threatening disease that can be treated all the more successfully the faster therapy is initiated. It is not just the infection itself that is so dangerous, but a dysregulated response of the immune system. Physicians at Ulm University Hospital have now developed an animal-free test system that can be used to research the disease and develop innovative diagnostic tools to quickly assess a patient's sepsis risk and optimise…

    https://www.gesundheitsindustrie-bw.de/en/article/news/whole-blood-model-enables-development-early-warning-system-sepsis
  • Press release - 09/02/2021

    New rapid test to detect coronavirus antibodies developed

    An international research team involving the universities of Paraná and Tübingen has developed a rapid test that can reliably identify Covid-19 antibodies in the blood within minutes. As the researchers report in the journal ACS Sensors, the new process is based on a simple measuring principle making it easy to carry out without expensive instruments, and is therefore suitable for use at mobile testing centers or by laboratories.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-rapid-test-detect-coronavirus-antibodies-developed
  • Press release - 07/12/2020

    One for all

    AI-based evaluation of medical imaging data usually requires a specially developed algorithm for each task. Scientists from the German Cancer Research Center (DKFZ) have now presented a new method for configuring self-learning algorithms for a large number of different imaging datasets – without the need for specialist knowledge or very significant computing power.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/one-all
  • Development of the genomDE genome database - 04/12/2020 national-cancer-institute-to8o0bqOA6Q-unsplash.jpg

    Whole genome sequencing for diagnosing rare diseases

    Grouped together, rare diseases are by no means a rare phenomenon; however, they are rarely correctly diagnosed and rarely properly treated. In most cases, there is no effective medication available. Rare disease centres staffed by experts have been set up in many German cities to speed up the often long and painful search for the right diagnosis and treatment. Whole genome sequencing is a component of general healthcare, used to identify…

    https://www.gesundheitsindustrie-bw.de/en/article/news/whole-genome-sequencing-diagnosing-rare-diseases
  • New method for analysing blood samples - 26/11/2020 Bildschirmfoto_2020-10-30_um_11.46.25.png

    Personalised therapy monitoring for malignant melanomas

    Immunotherapy has greatly improved the survival chances of patients with malignant melanoma. A study has now begun at the Department of Dermatology at the University Hospital of Tübingen to develop a way to monitor the course of treatment as effectively as possible. It involves personalised monitoring using liquid biopsies in addition to conventional PET/CT examinations. This analysis procedure of blood samples could enable closer monitoring of…

    https://www.gesundheitsindustrie-bw.de/en/article/news/personalised-therapy-monitoring-malignant-melanomas
  • Lab-on-a-chip - 11/11/2020 Bild_3.jpg

    Microfluidic platform for the best possible cancer therapy

    Every tumour and every patient is different, and there are individual reactions to drugs as well as the problem of resistance. Patient-specific cancer treatments require innovative and cost-effective approaches. The TheraMe! consortium has developed a novel instrument: a combination of microfluidic experiments and mathematical modelling for use in cancer precision medicine to prevent incorrect therapy options.

    https://www.gesundheitsindustrie-bw.de/en/article/news/microfluidic-platform-best-possible-cancer-therapy
  • Press release - 09/11/2020

    Making sense of what you see in biomedical images

    Sometimes an image is just an image. Sometimes it gives those who can read it correctly a deeper insight into what they can see. In many scientific disciplines, the key to extracting meaningful information from large three-dimensional images, obtained from X-ray tomography or optical microscopy, is segmentation, a tedious and time-consuming – and therefore error-prone – task if done manually.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/making-sense-what-you-see-biomedical-images
  • Press release - 09/11/2020

    Infection diagnostics 3.0: Faster thanks to nanopore sequencing

    To ensure that sepsis patients receive appropriate antibiotics as quickly as possible, Fraunhofer IGB researchers have developed a diagnostic procedure that uses high-throughput sequencing of blood samples and delivers results much faster than conventional culture-based techniques. Thanks to the latest single-molecule sequencing techniques, this process has now been further improved so that pathogens can be identified after just a few hours.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/infection-diagnostics-30-faster-thanks-nanopore-sequencing

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