Healthcare industry

The first European Conference for Clinical Nanomedicine is to be held soon in Basel. BIOPRO has therefore discussed this promising area of application with Beat Löffler and Dr. Patrick Hunziker the founders of the European Foundation for Clinical Nanomedicine.

Dossier - 07/02/2011

The era of personalised medicine is dawning

A promising future does not easily disappear into thin air. This is certainly the case with the vision of personalised medicine. For many years, biomedical researchers have vaunted the potential benefits of their findings despite the fact that neutral observers do not think that personalised medicine will really take off within the next 15 or 20 years. Moreover personalised medicine is a controversial term. So what is the state of play right now?

Article - 05/06/2012

Max Planck Director Izaurralde honored for groundbreaking research

Professor Dr. Elisa Izaurralde has made important contributions to the field of RNA biology in recent years. The managing director of the Max Planck Institute for Developmental Biology in Tübingen explores the complex mechanisms of cellular gene regulation. For her work on mRNA regulation she has now been honored with the prestigious Ernst Jung Prize for Medicine.

Article - 14/08/2018

Simple and fast: new optical method for analysing living cells

The junior researchers Dr. Daniel Geiger, Tobias Neckernuß and Jonas Pfeil from Ulm have developed an innovative method for non-contact real-time analysis of cells and other particles. The analysis involves low data rates and correspondingly little effort. This is what makes the method so attractive for medical applications.

Press release - 15/11/2010

ASPEX- an advanced Schizosaccharomyces expression system

The ASPEX system Asahi Glass Schizosaccharomyces Expression is a full-scale contract manufacturing service for recombinant proteins with up to the 3000 L scale. It is based on S. pombe an endotoxin-free fission yeast isolated from east African beer. Examples for gene expressions in the ASPEX system are manifold. The dedicated production facility located close to the Research Center is organized under cGMP rules and thus enables supply of…

Five new companies from the Stuttgart/Tübingen region in southwestern Germany have joined the Cyber Valley Start-Up Network. The innovative technologies and products of AmbiGate, Cytolytics, Mojin Robotics, plus10 and Tactai aim to achieve ground-breaking improvements in the fields of public health, manufacturing, and customer service. These start-ups join ten other companies that are already part of the Cyber Valley Start-Up Network.

Biametrics Marken and Rechte GmbH has developed new analytical devices based on reflectometric interference spectroscopy thus adopting the trend of label-free detection methods. This is because labelling tends to interfere with the natural activity of the biomolecules under investigation.

Article - 19/01/2015

Kay Gottschalk and the physics of cells

You learn a great deal about the physical aspects of cells when you talk to Prof. Dr. Kay-E. Gottschalk. For example, their ability to react as solid and liquid, to adapt their environment to suit themselves and to exert and respond to forces. The 42-year-old has great respect for the smallest of living units, i.e. cells, which he calls smart composite materials. Working on the boundaries of medicine, biology, chemistry and physics, Gottschalk…

Article - 14/12/2016

Transcranial brain stimulation to counteract chronic tiredness

You may well be familiar with the ”leaden” feeling associated with lack of sleep. However, chronic tiredness lasting many months might be a sign of a serious disease. Dr. Lukas Frase, together with Prof. Dr. Christoph Nissen’s team at the Freiburg University Medical Center’s Department of Psychiatry and Psychotherapy, has come up with a method to help patients with abnormally high sleep needs. The method uses weak electrostimulation and has the…

So-called silent mutations have no effect on the composition of a protein. They are therefore not considered to promote cancer. However, scientists from the German Consortium for Translational Cancer Research (DKTK), partner site Essen, now describe in a case of kidney cancer an overlooked silent mutation with a major impact on prognosis.

Scientists of the German Cancer Research Center DKFZ in Heidelberg have now shown that inspection of both sides of the colon also reduces cancer risk in the right part of the colon by more than 50 percent. The overall risk was found to be 77 percent lower. This means that colonoscopy provides very good protection from colon cancer - even though it is not a 100 percent guarantee.

The University of Tübingen opened its new laboratory for Preclinical Imaging and Imaging Technology of the Werner Siemens Foundation. The professorship is the only one in Europe combining preclinical imaging and the development of new imaging technologies.

Press release - 20/01/2008

LifeCodexx AG - Clarity within the genetic data jungle

Constance based GATC Biotech founds the subsidiary company LifeCodexx AG. LifeCodexx is the first web-based information service for the storage and utilisation of biological and medical data from the analysis of genetic codes and protein codes in the EU.

Article - 21/07/2014

Predicting the efficiency of cancer drugs using mathematical models

A research consortium was established at the Stuttgart Research Center Systems Biology SRCSB at the University of Stuttgart in January 2013 with the goal of establishing models that help predict the action of targeted therapeutics. The scientists combine molecular biology experiments with complex mathematical models in order to achieve a holistic understanding of disease and therapy.

The X-ray-based determination of bone density is currently the only method that enables the early diagnosis of osteoporosis. However this examination method has rather limited informative value. That is why the University Hospital in Tübingen is now establishing high-resolution magnetic resonance imaging MRI that provides the physicians with completely new insights into the microarchitecture of the bones.

Article - 06/03/2011

Heidelberg Translational Lung Research Centre

University and non-university research institutions in Heidelberg that carry out research into lung diseases have established an expert network – the Heidelberg Translational Lung Research Centre – which is part of the new BMBF-funded German Centre for Lung Research. In Heidelberg, research focuses on the development and treatment of cystic fibrosis, chronic obstructive pulmonary diseases and lung cancer.

Article - 03/03/2016

Liquid biopsies – beacons of hope for cancer diagnosis?

Researchers around the world, including researchers from the Freiburg University Medical Center, are working on developing simple blood tests, so-called liquid biopsies, that can be used to obtain accurate information about tumour staging and the progress of therapy. An international liquid biopsy symposium was held in Freiburg in October 2015 and has produced valuable insights.

Press release - 01/06/2011

Heidelberg expert to coordinate European network on inherited metabolic disorders

A European network for research into rare inherited metabolic disorders will be coordinated by PD Dr. Stefan Kölker, head of the Division of Inherited Metabolic Diseases at the Centre for Paediatric and Adolescent Medicine, University of Heidelberg. The project, which will initially run for three years, has a financial volume of 1.3 million euros. More than 40 partners from 17 European countries are part of the “European registry and network for…

Article - 14/12/2009

Clever surveillance system keeps yeast in check

The spectrum of human diseases (mycoses) caused by fungi ranges from trivial nail infections to life-threatening systemic infections. The latter are mainly caused by Candida albicans. The dermatologist Prof. Dr. med. Martin Schaller from Tübingen is investigating how this fungus, which is actually part of the normal microbial flora of humans, becomes a pathogen. At the same time, he is looking into the role the patient’s immune system plays in…

The NMI Natural and Medical Sciences Institute in Reutlingen organised its biannual MEA conference from 8 to 11 July 2008. More than 200 developers and microelectrode array users from 18 countries came together in Reutlingen to present their latest developments and results.

Article - 22/12/2014

The immune system – both weak and overreactive in the absence of CTLA4

The ability to recognise a pathogen and combat it effectively is certainly one of the most complex and sophisticated processes the human body has evolved. People with an immunodeficiency or autoimmune disease may have a genetic defect in one of the genes involved in the immune response. Working with immunologists from London scientists Desire Schubert and Prof. Dr. Bodo Grimbacher from the Centre for Chronic Immunodeficiency CCI at the Freiburg…

Expert interview - 08/08/2018

Ludolph: diagnosing and treating neurodegenerative disorders

Ulm has long been a world leader in diagnosing and treating rare neurological disorders, notably amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Huntington's disease (HD). We spoke with Professor Albert C. Ludolph, spokesperson for the Ulm DZNE site, medical director of the Clinic for Neurology at the RKU (University and Rehabilitation Clinics of Ulm) and world-renowned ALS researcher.

The great potential of artificial intelligence (AI) and machine learning for the life sciences – from basic research in biology to medical applications – has largely been neglected to date. A new research unit aims to support AI research in the life sciences and to forge international links with the activities in Heidelberg.

Article - 16/01/2009

Study: nutritional and dietary treatments for ADHD

Doctors and researchers have been at odds for many years as to whether long-chain polyunsaturated fatty acids have an effect on the behaviour and cognition of ADHD children. It is hoped that a study at Ulm University will bring more clarity to the debate and potentially come up with an alternative to the controversial psychostimulant therapy.

Press release - 05/09/2017

Cell marking opens up a window into the body

A new and particularly reliable method for marking cells can simplify research into diseases such as myocardial infarction, diabetes or Alzheimer's and reduce the use of test animals: Scientists from the University of Tübingen have developed a method by which they can target specific cell types in mice and monitor their behavior using positron emission tomography (PET). PET-based cell tracking allows scientists to observe complex life…