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  • Press release - 12/11/2012 16634_de.jpg

    Searching for new strategies against prostate cancer

    The European Research Council (ERC) has announced that Roland Schüle, Scientific Director at the Department of Urology, University of Freiburg Medical Centre has been awarded an ERC Advanced Grant. Professor Schüle will receive €2.5 million for a period of 5 years for his research proposal to identify and characterize the molecular and physiological functions of the epigenetic enzyme LSD1 and to explore its role in prostate cancer.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/searching-for-new-strategies-against-prostate-cancer
  • Dossier - 05/11/2012 18550_de.jpg

    Cancer – basic research, successes and trends

    Science is approaching cancer treatment by using new systems biology approaches and setting up large-scale multidisciplinary projects such as the International Cancer Genome Consortium. Progress in genome, epigenome and gene expression analyses of cancer cells, new insights into the regulation and interaction of cells gained in cooperation with stem cell research and virus research contributes to gaining a causal understanding of cancer. This…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/cancer-basic-research-successes-and-trends
  • Article - 15/10/2012 18357_de.jpg

    ERC Starting Grants 2012: Baden-Württemberg achieves above-average success

    On September 10th 2012, the European Research Council (ERC) announced the results of the fifth funding round of its Starting Grants. Baden-Württemberg was awarded 13 grants, and is the state with the largest number of a total of 34 grants awarded to German life sciences researchers. Baden-Württemberg life sciences researchers will be receiving Starting Grants worth around 20 million euros.

    https://www.gesundheitsindustrie-bw.de/en/article/news/erc-starting-grants-2012-baden-wuerttemberg-achieves-above-average-success
  • Article - 17/09/2012 The photo shows a rosette-like structure consisting of differently coloured subunits.

    Biochemisty and the assembly of ammonium machines

    Researchers who intend to build enzymes in the laboratory need detailed knowledge about the function of the respective enzymes. Using modern biochemistry methods researchers led by Prof. Dr. Oliver Einsle from the University of Freiburg have in the last few years clarified the atomic structure of a complex bacterial protein that converts atmospheric nitrogen into a form that can be readily used by other organisms. The researchers have recently…

    https://www.gesundheitsindustrie-bw.de/en/article/news/biochemisty-and-the-assembly-of-ammonium-machines
  • Article - 06/08/2012 17713_de.jpg

    varionostic: specialist in epigenetic analyses

    Ulm-based varionostic helps epigenetics researchers to obtain information on gene activity. The company is specifically focused on the analysis of methyl groups (-CH3) that are attached to DNA and turn genes on and off. Just as the field of epigenetics, previously only known to insiders, has emerged as a biomedical area of research, the University of Ulm spin-off has matured and grown over the past six years since it was set up.

    https://www.gesundheitsindustrie-bw.de/en/article/news/varionostic-specialist-in-epigenetic-analyses
  • Press release - 03/08/2012 17813_de.jpg

    Dosage compensation in male flies: Balance between sexes

    The sex of many organisms is determined by the number of X chromosomes. In humans women have two X chromosomes whereas men have only one but also have an additional Y chromosome. Why this does not result in an imbalance in the expression of important genes on the X chromosome is what researchers at the Max Planck Institute in Freiburg have examined in collaboration with researcher in Cambridge UK. They have been able to show that the initiation…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/dosage-compensation-in-male-flies-balance-between-sexes
  • Press release - 04/06/2012 12300_de.jpg

    DFG establishes 20 new Collaborative Research Centres

    The support ranges from new therapies for multiple sclerosis via the heroic tradition in ancient time to functional microgels. Attached is a selection of research approaches in science in Baden-Württemberg.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/dfg-establishes-20-new-collaborative-research-centres
  • Article - 21/05/2012 17201_de.jpg

    Interactions between the genome and the environment

    Parental neglect appears to lead to epigenetic changes in children, which result in behavioural problems in later years. This is one issue amongst the many that were addressed at the colloquium “Gene und Umwelt – Wie wir werden, was wir sind” (Genes and the environment – how we become what we are) recently organized by the Daimler and Benz Foundation in Berlin.

    https://www.gesundheitsindustrie-bw.de/en/article/news/interactions-between-the-genome-and-the-environment
  • Article - 23/04/2012 16983_de.jpg

    Iris-Tatjana Kolassa – extreme stress takes a toll on cells

    Molecular psychology has huge potential for the future. The discipline has used imaging methods for diagnostic purposes for a long time, but Iris-Tatjana Kolassa, a 33-year-old psychologist from Ulm, is convinced that in future it will increasingly use molecular biology and medicine methods. The idea of remaining blinkered in her own discipline is a notion that is utterly foreign to Kolassa; whenever she senses synergies, whether it be with…

    https://www.gesundheitsindustrie-bw.de/en/article/news/iris-tatjana-kolassa-extreme-stress-takes-a-toll-on-cells
  • Article - 05/03/2012 The photo shows nine people standing on a staircase.

    Ubiquitin and related molecules do more than just degrade and recycle cellular waste

    The proteins of the ubiquitin family have long been regarded as cellular Post-its with to be discarded written on them. However over the last ten years it has become increasingly clear that the proteins of the ubiquitin family that cells use to label defective or unneeded proteins also regulate a broad range of important cellular processes. It has also been found that they are involved in the pathogenesis of cancer and neurodegenerative diseases…

    https://www.gesundheitsindustrie-bw.de/en/article/news/ubiquitin-and-related-molecules-do-more-than-just-degrade-and-recycle-cellular-waste
  • Press release - 01/02/2012 Logo DKFZ, blue letters "DKFZ"

    Defects in the packaging of genetic material in malignant brain tumors

    Glioblastomas are regarded as particularly aggressive brain tumors. In children with glioblastoma, Heidelberg scientists have now discovered genetic alterations that affect the function of DNA packaging proteins known as histones. In a cell, histones serve as coils around which the DNA wraps. At the same time, histones regulate gene activity. Mutations in histone genes have never before been tied to a disease. The group comprising scientists of…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/defects-in-the-packaging-of-genetic-material-in-malignant-brain-tumors
  • Article - 16/01/2012 The photo shows fifteen people standing in front of a building.

    Manfred Jung: drug discovery and the epigenetic code

    Prof. Dr. Manfred Jungs team at the University of Freiburg are chemical epigeneticists whose research involves the development of methods that enable them to identify and optimise new therapeutic drugs which are able to alter the epigenetic code of cancer and other cell types. The team use a perfidious worm for their research.

    https://www.gesundheitsindustrie-bw.de/en/article/news/manfred-jung-drug-discovery-and-the-epigenetic-code
  • Article - 19/12/2011 16054_de.jpg

    Patrick Heun: The DNA tangle and how it is organised

    Dr. Patrick Heun and his group of researchers at the Max Planck Institute MPI of Immunobiology and Epigenetics in Freiburg are working on elucidating the spatial organisation of cell nuclei and how the structure of chromosomes is passed on to daughter cells during the division of cells. The researchers have come up with clear proof that the formation of centromeres depends on a single molecule.

    https://www.gesundheitsindustrie-bw.de/en/article/news/patrick-heun-the-dna-tangle-and-how-it-is-organised
  • Article - 12/12/2011 16001_de.jpg

    Comprehensive Biomarker Center GmbH – next-generation biomarkers

    Biomarker research has moved on from proteins to nucleic acids where one of the main priorities is the use of microRNA expression profiles. The Heidelberg-based biotech company Comprehensive Biomarker Center GmbH (CBC, formerly febit) has state-of-the-art technologies and the skills and knowledge to advance the development of new nucleic acid biomarkers for complex diseases in cooperation with partners from research and industry.

    https://www.gesundheitsindustrie-bw.de/en/article/news/comprehensive-biomarker-center-gmbh-next-generation-biomarkers
  • Press release - 05/12/2011 10163_de.JPG

    Cellzome founder wins EU women innovators award

    Cellzome announces 5 December 2011 that Dr. Gitte Neubauer has received the highly esteemed EU Women Innovators Award. The award recognizes her outstanding contribution in translating academic research into a commercial venture through the foundation of Cellzome. The prize value of 100.000 euros awarded by the European Commission Innovation Union was presented by Jos Manuel Barroso in a ceremony as part of the Innovation Convention 2011 in…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/cellzome-founder-wins-eu-women-innovators-award
  • Article - 14/11/2011 15790_de.jpg

    Marina Freudenberg and Chris Galanos – more than 40 years of bacterial defence research

    This years Nobel Prize in Medicine or Physiology was awarded to three renowned scientists one of whom is the American Bruce Beutler who was instrumental in clarifying the structure of the mammalian Toll-like 4 TLR4 receptor. Prof. Dr. med. Marina Freudenberg and Dr. Dr. h.c. Chris Galanos from the Freiburg-based Max Planck Institute MPI of Immunobiology and Epigenetics have co-authored the key publication that led to the award of the Nobel Prize…

    https://www.gesundheitsindustrie-bw.de/en/article/news/marina-freudenberg-and-chris-galanos-more-than-40-years-of-bacterial-defence-research
  • Press release - 21/09/2011 15391_de.jpg

    Epigenetic changes don’t last

    First comprehensive inventory of epigenetic changes over several generations shows that these often do not last and therefore probably have limited effects on long-term evolution. The team around Detlef Weigel, director of the Department for Molecular Biology, focused on one of the most important epigenetic marks, methylation of DNA.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/epigenetic-changes-don-t-last
  • Article - 25/07/2011 14841_de.jpg

    Silke Brüderlein has “green fingers” for cell cultures

    Many researchers in the biosciences work with cell cultures, but not all of them seem to understand them at a deeper level. The biologist Silke Brüderlein from the Institute of Pathology in Ulm is a specialist in cell culture and is well aware of the problems that might arise when working with cell cultures.

    https://www.gesundheitsindustrie-bw.de/en/article/news/silke-bruederlein-has-green-fingers-for-cell-cultures
  • Press release - 13/07/2011 14775_de.jpg

    Kinetochores prefer the “silent” DNA sections of the chromosome

    The centromere is a specialized region of the chromosome, on which a protein complex known as the kinetochore is assembled. During cell division, the kinetochore provides a point of attachment for molecules of the cytoskeleton, thereby mediating the segregation of chromosomes to the two opposing cell poles. Scientists from the Max Planck Institute of Immunobiology and Epigenetics and BIOSS in Freiburg have investigated the factors that play an…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/kinetochores-prefer-the-silent-dna-sections-of-the-chromosome
  • Article - 27/06/2011 14598_de.jpg

    The EURAT project at the Marsilius Kolleg in Heidelberg

    Bioinformaticians, human geneticists, molecular biologists, oncologists, pathologists, lawyers and theologians are all participating in the project “Ethical and legal aspects of the total sequencing of the human genome” (EURAT) being carried out at Heidelberg University’s Marsilius Kolleg. The project partners are developing a common viewpoint and working out solutions for problems arising from the possibilities of total genome sequencing.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-eurat-project-at-the-marsilius-kolleg-in-heidelberg
  • Article - 20/06/2011 14555_de.jpg

    Molecular biologists to celebrate 50th anniversary of Jacob and Monod’s operon model

    Leading molecular biologists from around the world came together at a conference jointly organized by the European Molecular Biology Organisation (EMBO) and the Institut Pasteur in Paris between 17th and 20th May to celebrate the 50th anniversary of the operon concept published by François Jacob and Jacques Monod in 1961. The scientists discussed concepts and research results influenced by the operon model, which have led to our present…

    https://www.gesundheitsindustrie-bw.de/en/article/news/molecular-biologists-to-celebrate-50th-anniversary-of-jacob-and-monod-s-operon-model
  • Article - 14/06/2011 14497_de.jpg

    Retinitis pigmentosa: a new form of cell death

    What form of cell death do the photoreceptors of people suffering from retinitis pigmentosa undergo and how can their degeneration be prevented or delayed with pharmaceutical substances? Dr. Paquet-Durand from the Institute for Ophthalmic Research in Tübingen is working to resolve these questions.

    https://www.gesundheitsindustrie-bw.de/en/article/news/retinitis-pigmentosa-a-new-form-of-cell-death
  • Article - 30/04/2011 The photo shows many gray thread-like structures<br />

    More efficient ways to erase cell memory

    Around five years ago for the first time ever regeneration biologists successfully turned back fully differentiated body tissue into pluripotent stem cells using a specific mixture of transcription factors. However the idea that it may one day become possible to create organ tissue is still a distant dream. The quantity of stem cells that can be obtained with current methods is still far too low. Dr. Maria Manukyan from the Centre for Biological…

    https://www.gesundheitsindustrie-bw.de/en/article/news/more-efficient-ways-to-erase-cell-memory
  • Article - 30/04/2011 14239_de.jpg

    The DKFZ-ZMBH Alliance

    The strategic alliance between the cell and tumour biology research priority at the German Cancer Research Center and the Center for Molecular Biology at Universität Heidelberg has led to the development of one of the largest centres of basic biomedical research in Germany. The top international profile of this interdisciplinary institution located at the interface between molecular and cellular biology tumour biology and biomedicine is reflected…

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-dkfz-zmbh-alliance
  • Press release - 15/02/2011

    Cellzome Announces Achievement of Second Milestone in Epigenetics Collaboration with GSK

    Cellzome announced today that it has achieved the second milestone in its epigenetics alliance with GlaxoSmithKline. The milestone triggers a payment of an undisclosed amount from GSK and follows only two months after the first milestone was achieved.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/cellzome-announces-achievement-of-second-milestone-in-epigenetics-collaboration-with-gsk

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