Article - 16/05/2011 New analysis tools involving molecularly imprinted polymers The demand for made-to-measure analytical methods is increasing as interest in the biological production of materials and pharmaceuticals increases. It is extremely important economically for bioindustry to know the production time and quantity of products that result from specific fermentation conditions. Inspired by natural molecular processes, researchers from Tübingen and Stuttgart are working on new, label-free analytical methods that make…https://www.gesundheitsindustrie-bw.de/en/article/news/new-analysis-tools-involving-molecularly-imprinted-polymers
Press release - 13/11/2009 Second-generation biofuels The Distillery for Research and Training at the University of Hohenheim has been reopened after the completion of renovation work costing around 1.2 million euros. The distillery is now equipped with a computer-operated process-control system and modern sensors, all state-of-the-art technology for the fermentation processes at Hohenheim. The new distillery pilot plant has a fermentation room for work with genetically modified organisms.…https://www.gesundheitsindustrie-bw.de/en/article/press-release/second-generation-biofuels
Expert interview - 17/10/2018 Biologicals are becoming increasingly important to Boehringer Ingelheim Biopharmaceuticals are playing an increasingly important role in Boehringer Ingelheim’s development pipeline. Visible evidence of this is the company’s Biologicals Development Centre (BDC) that is currently being constructed in Boehringer Ingelheim’s Biberach plant and will bring the company’s process development under one roof by early 2020. Walter Pytlik from BIOPRO talked with Dr. Ing. Ralf Schumacher about the new centre.https://www.gesundheitsindustrie-bw.de/en/article/news/biologicals-are-becoming-increasingly-important-to-boehringer-ingelheim
Article - 19/03/2012 Goal: online glucose sensor for bioreactors Microorganisms and sensitive cells that are grown in bioreactors need a well-regulated environment and a food supply in order to do what they are supposed to do: grow and produce biomass and metabolites. Many fermenters are equipped with sensors that continuously measure critical bioprocess parameters, including temperature, pH value and oxygen. Online glucose and ethanol sensors are not yet used in regulated bioreactors, even though they would…https://www.gesundheitsindustrie-bw.de/en/article/news/goal-online-glucose-sensor-for-bioreactors
Article - 25/07/2011 Cell culturing as a taught subject: many more “Biberachs” are needed Cell culture technology is only taught at a handful of universities. However, this interdisciplinary subject is the core of the “Pharmaceutical Biotechnology” programme offered by the Biberach University of Applied Sciences. We talked about the subject with Professor Jürgen Hannemann, founding dean of the “Pharmaceutical Biotechnology” programme, and with Professor Friedemann Hesse, who runs the “cell culture technology” teaching programme.https://www.gesundheitsindustrie-bw.de/en/article/news/cell-culturing-as-a-taught-subject-many-more-biberachs-are-needed
Article - 30/07/2009 Dragnet investigation for substance killers The Ulm-based company Labor Dr. Merk Kollegen with over 40 employees is a specialist company identifying foreign bodies such as viruses bacteria and toxins in biopharmaceuticals and medical products. In addition the medium-sized company has been developing producing and marketing diagnostics for medical use for almost 40 years.https://www.gesundheitsindustrie-bw.de/en/article/news/dragnet-investigation-for-substance-killers
Press release - 09/09/2010 Jiangnan University, Wuxi Jiangnan University JU is one of Chinas key universities of the 211 Project and functions under the Ministry of Education. The university host the National Engineering Laboratory of Fermentation Technology the Key Laboratory of Industrial Biotechnology the Engineering Research Center of Bioactive Product Processing Jiangsu Province and the Collection of Industrial Microbes Resources. https://www.gesundheitsindustrie-bw.de/en/article/press-release/jiangnan-university-wuxi
Article - 02/06/2008 New production alliance in South West Germany Rentschler Biotechnologie and Boehringer Ingelheim have signed a preferred partnership agreement. Clients will benefit from the combined development and manufacturing know-how. Compatible bioprocessing methods guarantee a seamless project transfer between the companies.https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-production-alliance-in-south-west-germany
Press release - 21/08/2012 Freiburg research team sheds light on important metabolite in bacteria Scientists from the research groups of Prof. Dr. Susana Andrade and Prof. Dr. Oliver Einsle, members of the Institute of Organic Chemistry and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence of the University of Freiburg, have collected the first precise data ever on the function of a transport protein for formate – an important metabolite in bacteria. The findings could potentially lead to the development of new antibiotic…https://www.gesundheitsindustrie-bw.de/en/article/press-release/freiburg-research-team-sheds-light-on-important-metabolite-in-bacteria
Article - 24/09/2009 Bacteria to produce bioplastics Polyhydroxyalkanoates are storage substances produced and stored by many cells plants and bacteria only in times when they lack lack important nutrients. A particular property of these plastics-related biopolymers is that their composition and hence their material properties can be regulated by the fermentation process.https://www.gesundheitsindustrie-bw.de/en/article/news/bacteria-to-produce-bioplastics
Article - 16/06/2016 Microfluidic biofermenter mimics plant tissue It is estimated that as many as one million secondary plant metabolites can be used as medical agents. Plants produce these compounds to aid their growth and development as well as to discourage herbivores from eating them. However, it is still very difficult, or even impossible, to produce secondary plant metabolites industrially. Researchers from the Karlsruhe Institute of Technology (KIT) are now developing a microfluidic bioreactor to make…https://www.gesundheitsindustrie-bw.de/en/article/news/microfluidic-biofermenter-mimics-plant-tissue
Dossier - 30/07/2009 Downstream processing: bottleneck purification process The fermentation processes that are used by biopharmaceutical manufacturers have shown to lead to increasing quantities of therapeutic proteins. However this increase in turn leads to capacity bottlenecks in the subsequent purification process known as downstream processing and is associated with high costs. Downstream processing comprises up to 80 per cent of the entire production costs. Producers are increasingly recognising the present need…https://www.gesundheitsindustrie-bw.de/en/article/dossier/downstream-processing-bottleneck-purification-process
Article - 23/10/2009 Agrano – organic yeast for the industry Riegel-based Agrano GmbH & Co. has been producing Bioreal Organic Yeast since 1996. The company is a subsidiary of Hanover-based Martin Braun KG, which is a member of the Oetker Group. The company’s product is used by bakers in the production of organically flawless bread as well as makers of 100% organic soups and spreads.https://www.gesundheitsindustrie-bw.de/en/article/news/agrano-organic-yeast-for-the-industry
Article - 14/10/2010 Understanding what happens in dough In cooperation with the Nestl Research Centre Dr. Helmut Trautmann with his company abiotec AG has developed a gas volume monitor for the analysis of dough samples. The monitor makes an important contribution to the development as well as to the quality assurance of food. In addition to being used in the food technology sector the highly sensitive measurement device can also be used in the pharmaceutical and environmental sectors for example in…https://www.gesundheitsindustrie-bw.de/en/article/news/understanding-what-happens-in-dough
Press release - 15/11/2010 ASPEX- an advanced Schizosaccharomyces expression system The ASPEX system Asahi Glass Schizosaccharomyces Expression is a full-scale contract manufacturing service for recombinant proteins with up to the 3000 L scale. It is based on S. pombe an endotoxin-free fission yeast isolated from east African beer. Examples for gene expressions in the ASPEX system are manifold. The dedicated production facility located close to the Research Center is organized under cGMP rules and thus enables supply of…https://www.gesundheitsindustrie-bw.de/en/article/press-release/aspex-an-advanced-schizosaccharomyces-expression-system
Article - 01/03/2017 foxySpec – an analysis system with huge potential for bioproduction and diagnostics The mass spectrometry-based foxySpec system enables the monitoring of gases and liquids simultaneously in real time. These simultaneous measurements make the system interesting for medical diagnostics applications. However, bioproduction can also benefit from foxySpec, which can also be used to measure a large number of products during the production process in real time, thus supporting smooth processes in fermenters. https://www.gesundheitsindustrie-bw.de/en/article/news/foxyspec-an-analysis-system-with-huge-potential-for-bioproduction-and-diagnostics
Dossier - 16/06/2014 Biotechnology as a tool for the production of food Biotechnology opens up numerous opportunities for the food industry. The targeted use of biotechnological methods can, amongst other things, help reduce the quantity and number of unhealthy ingredients in foods as well as degrade allergenic substances. Genomic research and targeted breeding also greatly facilitate progress in agriculture. Food biotechnology therefore contributes significantly to saving resources, optimising harvest yields and…https://www.gesundheitsindustrie-bw.de/en/article/dossier/biotechnology-as-a-tool-for-the-production-of-food
Dossier - 23/07/2012 Extremophilic bacteria What causes stress for some, actually speeds others like extremophilic bacteria up. They love it hot, sour or salty, toxic substances like heavy metals also do them good and even give them energy. As molecular and systems biology techniques get better and better, industry is also becoming increasingly interested in these exotic organisms. What potential does knowing the biochemistry of extremophilic bacteria have for the pharmaceutical, cosmetics…https://www.gesundheitsindustrie-bw.de/en/article/dossier/extremophilic-bacteria
Press release - 01/06/2012 DFG Europa-Preis awarded to winners of national "Jugend forscht" competition Four young researchers had two reasons to celebrate at this year's awards ceremony for Germany’s "Jugend forscht" competition in Erfurt. Not only did the young researchers place first in their respective fields, they were also awarded the Europa-Preis of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation).https://www.gesundheitsindustrie-bw.de/en/article/press-release/dfg-europa-preis-awarded-to-winners-of-national-jugend-forscht-competition
Article - 20/12/2010 Gicon: Using controllable biogas production to create virtual power stations Conventional biogas plants have the disadvantage that the production of energy cannot be controlled in a flexible way. Therefore, Großmann Ingenieur Consult GmbH (GICON) has developed a fast, simple method for controlling biogas production from renewable resources. In addition, the two-stage dry-wet fermentation process with split hydrolysis makes it possible to control the two stages independently. Heribert Krämer, head of the GICON subsidiary…https://www.gesundheitsindustrie-bw.de/en/article/news/gicon-using-controllable-biogas-production-to-create-virtual-power-stations
Article - 18/11/2013 Insilico Biotechnology AG: strategic orientation secures corporate growth Insilico Biotechnology AG from Stuttgart designs and optimises biotechnological processes for the chemical pharmaceutical and food industries. The company makes predictions on the behaviour of cells and organisms. This knowledge can be used to reduce the time required for the development or optimisation of biotechnological processes involving the production of drugs. The company owns a worldwide unique systems biology platform that integrates…https://www.gesundheitsindustrie-bw.de/en/article/news/insilico-biotechnology-ag-strategic-orientation-secures-corporate-growth
Article - 12/01/2011 How milk, cheese, yoghurt and curd cheese can be kept free from “genetic engineering” Bacteriophages introduce their DNA into bacteria where they quickly reproduce and eventually destroy the host organism. Phages are omnipresent in nature and some can be dangerous for humans. They also represent a huge contamination risk in the production of fermented food. Canadian researchers Lvesque et al. 2005 estimate that phages cause around 10 per cent of all production losses in the diary industry where they infest bacteria such as…https://www.gesundheitsindustrie-bw.de/en/article/news/how-milk-cheese-yoghurt-and-curd-cheese-can-be-kept-free-from-genetic-engineering
Press release - 26/06/2014 A great success – the first German-Chinese “Biotechnology in a Bioeconomy” workshop At the end of May the first German-Chinese workshop on the role of biotechnology in a future bioeconomy was held at the Karlsruhe Institute of Technology KIT with generous support from the Baden-Württemberg government. Researchers from Chinese Academy of Sciences institutes Tianjin Dalian Tsingtau and from the Chinese Universities of Beijing Nanking and Shanghai met with Baden-Württemberg experts to discuss the current state of research in China…https://www.gesundheitsindustrie-bw.de/en/article/press-release/a-great-success-the-first-german-chinese-biotechnology-in-a-bioeconomy-workshop
Article - 16/07/2012 Laupheim to become an international forum for biomanufacturing The 2nd Laupheimer Zelltage conference organized by Rentschler Biotechnologie GmbH in Laupheim on 11th and 12th June 2012 focused on “Bioprocess light”. Twelve experts from applied research institutions and biotech companies from Germany and abroad provided the 200 or so guests with information on how modern bioproduction methods can be made simpler, more robust, cheaper, more reliable and hence more competitive.https://www.gesundheitsindustrie-bw.de/en/article/news/laupheim-to-become-an-international-forum-for-biomanufacturing
Guest article - 15/04/2013 Varied and multi-facetted – life and research in Nanjing Joachim Koepff spent six months in Nanjing from June to November 2012 doing practical training at the College for Biotechnology and Pharmaceutical Engineering. Here he recounts his experiences in China and his thoughts about the Baden-Württemberg Ministry of Science Research and the Arts scholarship that makes such short-term research stays at a Chinese research institution possible.https://www.gesundheitsindustrie-bw.de/en/article/news/varied-and-multi-facetted-life-and-research-in-nanjing