Article - 31/01/2010 A view into the genome provides information on the lipid metabolism Since its foundation around 10 years ago the VIVIT institute in Dornbirn and Feldkirch has been dealing with the impact of disorders of the sugar and lipid metabolisms on the pathogenesis of diseases such as atherosclerosis liver damage or coronary heart disease. https://www.gesundheitsindustrie-bw.de/en/article/news/a-view-into-the-genome-provides-information-on-the-lipid-metabolism
Press release - 21/01/2010 Open access drug discovery database launches with half a million compounds ChEMBLdb a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets was launched on January 18 2010 with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new drugs in the clinic.https://www.gesundheitsindustrie-bw.de/en/article/press-release/open-access-drug-discovery-database-launches-with-half-a-million-compounds
Press release - 21/01/2010 Resequencing: HybSelect from febit in use The Molecular Genetics Core Facility (MGCF) at Children’s Hospital Boston chose febit’s HybSelect technology which will enable genetics researchers to conduct the highly economic targeted enrichment of genes of interest for resequencing. In January the core facility will be receiving the Geniom RT Analyzer® from febit to perform HybSelect.https://www.gesundheitsindustrie-bw.de/en/article/press-release/resequencing-hybselect-from-febit-in-use
Press release - 14/01/2010 Evolution caught in the act Mutations are the raw material of evolution. Charles Darwin already recognized that evolution depends on heritable differences between individuals: those who are better adapted to the environment have better chances to pass on their genes to the next generation. A species can only evolve if the genome changes through new mutations, with the best new variants surviving the sieve of selection. Scientists at the Max Planck Institute for…https://www.gesundheitsindustrie-bw.de/en/article/press-release/evolution-caught-in-the-act
Dossier - 11/01/2010 Green genetic engineering – a controversial future technology Green genetic engineering comprises a plethora of methods that enable the production of genetically modified (i.e. transgenic) plants by introducing extra genes, which are often foreign to the species into which they are introduced, into a plant genome. The number to be introduced can vary from one single gene to several genes. For example, in order to establish a new and foreign metabolic pathway in a particular plant, several genes need to be…https://www.gesundheitsindustrie-bw.de/en/article/dossier/green-genetic-engineering-a-controversial-future-technology
Press release - 17/12/2009 Germany Starts Its Part in the International Cancer Genome Project German scientists will participate in the largest and most ambitious biomedical research project since the Human Genome Project. Coordinated by the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), the German participants of the International Cancer Genome Consortium (ICGC) will start their work in early January. Their aim is to analyze the molecular causes of childhood brain tumors. https://www.gesundheitsindustrie-bw.de/en/article/press-release/germany-starts-its-part-in-the-international-cancer-genome-project
Press release - 01/12/2009 Stefan Wiemann elected new spokesman of the German Genome Research Network Associate Professor (PD) Dr. Stefan Wiemann of the German Cancer Research Centre (Deutsches Krebsforschungszentrum, DKFZ) has been elected spokesman of the Project Committee of the National Genome Research Network. This funding programme supports projects in medical genome research aimed at fighting relevant widespread diseases. https://www.gesundheitsindustrie-bw.de/en/article/press-release/stefan-wiemann-elected-new-spokesman-of-the-german-genome-research-network
Press release - 27/11/2009 Gene Mutations Underlying Risk for Parkinson's Disease Two genes containing mutations known to cause rare familial forms of parkinsonism are also associated with the more common, sporadic form of the disease where there is no family history, researchers have found. The finding came in the largest genome-wide association study (GWAS) reported to date involving Parkinson's disease.https://www.gesundheitsindustrie-bw.de/en/article/press-release/gene-mutations-underlying-risk-for-parkinson-s-disease
Press release - 23/11/2009 GATC Biotech soon opens sequencing laboratory in London GATC Biotech Europes leading sequencing service provider for industrial and academic research announces that it will open a sequencing laboratory in London to provide scientists in UK and Ireland with single sample sequencing services. The GATC London Laboratory will be situated in the London BioScience Innovation Centre LBIC and will start operations on January 4 2010. https://www.gesundheitsindustrie-bw.de/en/article/press-release/gatc-biotech-soon-opens-sequencing-laboratory-in-london
Article - 19/11/2009 Cellzome - kinase inhibitors for therapy Cellzome is a privately-owned biotechnology company which develops new drugs for the treatment of rheumatoid arthritis, multiple sclerosis and chronic inflammatory intestinal diseases at its two company sites in Heidelberg (Germany) and Cambridge (UK).https://www.gesundheitsindustrie-bw.de/en/article/news/cellzome-kinase-inhibitors-for-therapy
Article - 19/11/2009 Iwona Adamska helps plants exposed to light stress Light is a vital element for plants. They require light to carry out photosynthesis and to produce their body substance from inorganic substances such as water and carbon dioxide. On the other hand plants can also suffer from too much light. Plants have developed a number of protective mechanisms to survive light stress situations. The biologist Prof. Iwona Adamska from the University of Constance is looking closely into these protective…https://www.gesundheitsindustrie-bw.de/en/article/news/iwona-adamska-helps-plants-exposed-to-light-stress
Press release - 17/11/2009 iGEM team Freiburg: a standing order for gold medals The Bioware team from Freiburg, an important part of the bioss cluster of excellence, has once again achieved resounding success: one gold medal and two special prizes at the iGEM competition (international Genetically Engineered Machine), the largest event for up-and-coming scientists focusing on synthetic biology. It was the turn of the research group heads, junior professor Dr. Kristian Müller and Dr. Katja Arndt, to participate in the…https://www.gesundheitsindustrie-bw.de/en/article/press-release/igem-team-freiburg-a-standing-order-for-gold-medals
Press release - 16/11/2009 No-Entry Zones for AIDS Virus The AIDS virus (HIV) inserts its genetic material into the genome of the infected cell. Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown for the first time that the virus almost entirely spares particular sites in the human genetic material in this process. This finding may be useful for developing new, specific AIDS drugs. https://www.gesundheitsindustrie-bw.de/en/article/press-release/no-entry-zones-for-aids-virus
Article - 16/11/2009 New network for systems biology seed research What happens to plant seeds during germination? Researchers led by Dr. Gerhard Leubner from the University of Freiburg in collaboration with six international groups of researchers will be jointly looking into these processes. The virtual Seed (vSEED) consortium took first place in a field of 54 contestants in the European Research Era-Net Plant Genomics competition. What makes the scientists’ project so special is that they are planning to…https://www.gesundheitsindustrie-bw.de/en/article/news/new-network-for-systems-biology-seed-research
Press release - 11/11/2009 Hematopoietic stem cell treatment with a new gene therapy vector: A first success treating a brain disease Two children with adrenoleukodystrophy (ALD), a fatal brain disease, have been successfully treated with a new gene therapy vector. Two years after treatment, the disease evolution has been stopped, and no adverse effect of the gene therapy has been observed so far. The results of this clinical trial conducted by Drs Nathalie Cartier and Patrick Aubourg (Inserm, France) in collaboration with European partners have just been published in Science…https://www.gesundheitsindustrie-bw.de/en/article/press-release/hematopoietic-stem-cell-treatment-with-a-new-gene-therapy-vector-a-first-success-treating-a-brain-di
Article - 28/10/2009 State Viticulture Institute to combat mildew Powdery and downy mildew can destroy entire wine harvests. More than 150 years ago, breeders attempted to increase the plants’ natural resistance to mildew by crossing them with more mildew-resistant grape varieties as an alternative to external abatements using fungicides. The majority of breeders soon abandoned the effort; only a handful of breeders, including biologists from the State Viticulture Institute in Freiburg, still believed that this…https://www.gesundheitsindustrie-bw.de/en/article/news/state-viticulture-institute-to-combat-mildew
Article - 22/10/2009 On the track of fascinating diatoms Diatoms make a considerable contribution to the production of oxygen and biomass in the worlds oceans and aquatic ecosystems. However up until now little is known about the molecular biology and chemistry of these eukaryotic algae. Prof. Peter Kroth and his team at the University of Constance are hoping to shed more light on these algae. The team has recently been involved in the deciphering of the Phaeodactylum tricornutum genome research that…https://www.gesundheitsindustrie-bw.de/en/article/news/on-the-track-of-fascinating-diatoms
Press release - 13/10/2009 Polyclone partners with Innovendia Consulting in Germany and Europe European biotech-platform and drug discovery companies will have easier access to Polyclone Bioservices assay design and validation services through its newly announced partnership with Innovendia Consulting from Owingen. EU and national government funded consortia will benefit from the more immediate availability of Polyclones unique combination of in vitro in silico assay design and validation capabilities. https://www.gesundheitsindustrie-bw.de/en/article/press-release/polyclone-partners-with-innovendia-consulting-in-germany-and-europe
Press release - 24/09/2009 CeGAT: Tracking genes using cutting-edge technologies To adequately meet the growing demand for genetic diagnostics doctor scientist and bioinformatician Dr. Saskia Biskup and her husband business graduate Dr. Dirk Biskup founded the Center for Genomics and Transcriptomics or CeGAT for short in July 2009. As a supplier of DNA and RNA sequencing in the STERN BioRegion CeGAT which is based in the Technology park Tübingen Reutlingen TTR uses state-of-the-art high-throughput technologies to examine…https://www.gesundheitsindustrie-bw.de/en/article/press-release/cegat-tracking-genes-using-cutting-edge-technologies
Article - 10/09/2009 Chaperone research using baker’s yeast and bacteria Protein misfolding and aggregation can lead to neurodegenerative diseases such as Alzheimers. Prof. Elke Deuerling at the University of Constance is investigating the molecular helpers the chaperones and the key role that they have in protein folding. Deuerling uses the bakers yeast Saccharomyces cerevisiae and the bacterium Eschericia coli for her studies. Her studies involving E. coli have now shown that ribosome-associated chaperones are…https://www.gesundheitsindustrie-bw.de/en/article/news/chaperone-research-using-baker-s-yeast-and-bacteria
Press release - 10/09/2009 Genome-wide study to identify risk factors of Alzheimer’s disease A study carried out by an international team of scientists, including scientists from the Freiburg University Medical Centre, pooled 16,000 probands and produced large datasets for the identification of genes with an elevated risk for Alzheimer’s disease.https://www.gesundheitsindustrie-bw.de/en/article/press-release/genome-wide-study-to-identify-risk-factors-of-alzheimer-s-disease
Article - 10/09/2009 Excessive numbers of ageing stem cells accumulate without a guardian Adult stem cells grow older too. A group of researchers focusing on the ageing of stem cells at the Max Planck Institute in Ulm under the leadership of Leibniz prizewinner Lenhard Rudolph, has now made a surprising discovery in their research into telomer-associated ageing, which further substantiates this hypothesis.https://www.gesundheitsindustrie-bw.de/en/article/news/excessive-numbers-of-ageing-stem-cells-accumulate-without-a-guardian
Article - 26/08/2009 Are fruit flies on the rise again? An inconspicuous buzzing insect – it is difficult to imagine that such a creature could be used as a model for humans. Nevertheless, since the beginning of the 20th century Drosophila melanogaster has provided us with decisive insights into human genetics, development and neurobiology. Prof. Dr. Karl-Friedrich Fischbach of the University of Freiburg has been focusing on the development and function of the fruit fly brain for several decades. What…https://www.gesundheitsindustrie-bw.de/en/article/news/are-fruit-flies-on-the-rise-again
Dossier - 26/08/2009 Model organisms Given that everything is very individual in nature, how can a biologist come up with general statements about how life functions? The answers can only be found using models that represent the entire whole. Modern research uses representative species from the kingdom of bacteria, fungi, plants and animals to glean information about fundamental biological principles. How can the knowledge gained be transferred to other organisms, including humans?…https://www.gesundheitsindustrie-bw.de/en/article/dossier/model-organisms
Press release - 10/08/2009 How do immune cells recognise infectious pathogens? Scientists of the University of Heidelberg and the German Cancer Research Centre have clarified the functional principles of an important receptor for bacterial infections: immune cells recognise bacterial and viral pathogens with a receptor known as toll-like receptor 9 (TLR9), which mediates biochemical reaction chains in order to fend off intruders. This discovery made by the Heidelberg researchers paves the way to develop new anti-infective…https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-do-immune-cells-recognise-infectious-pathogens