Healthcare industry

Certain wavelengths of light encode vital information about the plants environment. Dr. Andreas Hiltbrunner an his team from the University of Freiburg has recently shown how phytochrome A transmits this information into the cell.

Prof. Christoph Cremer Cremer hopes to use the Vertico-SMI nanoscope to decipher the molecular secrets of cells. After the 4Pi microscopy this system is the second development of his scientific career to break through the barrier of optical microscopy.

A large international group of researchers including researchers from the University of Constance has succeeded in sequencing the genome of a marine alga. Microalgae which belong to the phytoplankton are the basis of the marine food chain.

Prof. Dr. Michael Reth is active in the field of immunology and signalling. He is an experienced scientist who is well aware of the difficulty and the cumbersome nature of deciphering signals and signalling pathways. The Freiburg bioss excellence cluster - the Centre of Biological Signalling Studies - is Reths brainchild. Karin Bundschuh from BioRegio Freiburg spoke with the scientist who works at the Max Planck Institute of Immunobiology and the…

Microbial cells long gave researchers the impression that they were in a state of complete disorder. Prof. Dr. Peter Graumann from the University of Freiburg investigates cell division in bacteria and knows that even microbes are highly organised.

In order to be able to manage the growing amount of information in the life sciences the international research community has developed numerous electronic databases over the last few years. Supported by sophisticated software programmes the stored information can now be analysed effectively. In parallel with work-intensive screening methods which involve many laboratory experiments scientists are increasingly relying on computer-based methods.

Professor Dr. Christoph Borner from the University of Freiburg and his team are investigating the molecular mechanisms of apoptosis. Their research also provides insights into the medical treatment of cells that do not want to die - cancer cells.

Scientists at the Max Planck Institute for Developmental Biology together with American colleagues have decoded the genome of the Pristionchus pacificus nematode. It consists of a large number of genes. The scientists gain insight into the evolution of parasitism.

Proteins that are involved in the development of an organism must be activated at the right time and then inactivated if no longer required. Scientists in Tübingen investigate the specific degradation of these proteins through specialised and highly selective systems of the cell.

Despite having thousands of applicable ideas and having set up his own company, Prof. Alfred Nordheim sees himself as a true basic scientist. At this year’s International Genetics Congress in Berlin, the director of the Interfaculty Institute of Cell Biology at the University of Tübingen was elected president of the International Genetics Federation (IGF).

Tübingen-based Hölle & Hüttner AG is taking over the entire share capital of Cologne-based INTAVIS Bioanalytical Instruments AG retroactively as of 1 January 2008. Both companies specialise in the development and marketing of systems for the automation of biochemical and molecular biological processes.

Proposals have to be submitted by 1 December 2008.

About a year ago Prof. Dr. Martin Schwemmle and his team at the University Hospital of Freiburg discovered a new starting point in the fight against the H5N1-virus. In the meantime the scientists are working together with the company Pike Pharma to develop a compound.

The first Web log was initiated in 1991. Since then an ever increasing number of scientists have been using these Internet diaries to communicate knowledge report about science comment on it and classify it. Web logs are an enrichment for science communication.

Claus Schwechheimer at the Centre for Plant Molecular Biology at the University of Tübingen has succeeded in identifying a protein function in plants which if it is understood might lead to important progress in human cancer research.

Cancer cells are dangerous foodies. They metabolise far greater amounts of sugar than healthy cells. Nuclear medicine experts make use of cancer cells craving for sugar since the advent of modern positron emission tomography PET. This has led to an improvement in the quality of cancer treatment.

Researchers in Ulm are hoping to find new ways to destroy bone marrow cancer multiple myeloma cells through radiation. The German Jos Carreras Leukaemia Foundation is funding the research with a total of about 300000 euros over three years.

Mobile DNA elements are able to change their position in the genome and mobilise entire gene groups as well as switch genes on and off. Professor Bodo Rak and his team at the University of Freiburg are investigating the effect of mobile DNA fragments on the evolution of E. coli bacteria.

Karlsruhe based quantiom bioinformatics has developed a software tool that enables the comparative analysis of chromosomes and that enables statements to be made on the correlation of genomic alterations and disease development.

Histone acetyltransferases HATs and their antagonists the histone deacetylases are important enzymes in epigenetic gene regulation. Scientists discovered new HAT inhibitors that are now being investigated for their potential as anti-cancer drugs.

Press release - 19/05/2008

Viruses caught red-handed

Prof. Thilo Stehle biochemist at the University of Tübingen wants to capture and accurately study the moment at which a virus binds to a cell. He is hoping that further insights into this process might some time enable the development of drugs.

During the second Conference on Systems Biology of Mammalian Cells SBMC the MTZ-Award for medically-oriented Systems Biology will for the first time be presented. The prize sum of 5000 Euro can be divided and will be granted to the three best dissertations.

Organisers and more than 300 participants were very enthusiastic about the European BioFine life sciences congress recently held in Freiburg. Four different life sciences conferences were organised . Freiburg will also host BioFine 2009.

The GABI-PRECISE consortium which originates from the Genome Analysis of the Plant Biological System GABI initiative has announced a cooperative project on the introduction of gene targeting in barley.

GATC Biotech announced that it has added to its facilities with a wholly owned subsidiary in Stockholm Sweden building on the Companys existing presence in Europe with offices in Germany France and England.