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  • Article - 16/07/2012 17526_de.jpg

    Laupheim to become an international forum for biomanufacturing

    The 2nd Laupheimer Zelltage conference organized by Rentschler Biotechnologie GmbH in Laupheim on 11th and 12th June 2012 focused on “Bioprocess light”. Twelve experts from applied research institutions and biotech companies from Germany and abroad provided the 200 or so guests with information on how modern bioproduction methods can be made simpler, more robust, cheaper, more reliable and hence more competitive.

    https://www.gesundheitsindustrie-bw.de/en/article/news/laupheim-to-become-an-international-forum-for-biomanufacturing
  • Dossier - 18/06/2012 17404_de.jpg

    Biobanks – treasure chests for biomedical research

    Biobanking is still a very specialist subject. The Research Committee at the German Bundestag, the Office of Technology Assessment at the German Bundestag and the German Ethics Council are all interested in this biomedical research tool, which is both necessary and meaningful. However, opinions with regard to the ethical, legal and technical approach to biobanks differ. Since March 2012 it has become absolutely clear that Germany will not pass a…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/biobanks-treasure-chests-for-biomedical-research
  • Article - 29/05/2012 17307_de.jpg

    Intestinal bacteria and human gut types

    The type of bacteria that colonize the human gut does not just influence our digestion and well-being. Metagenome sequencing has provided an international consortium involving scientists from the European Molecular Biology Laboratory at the University Hospital of Heidelberg with evidence that certain individuals have different gut types with different types of bacteria. Such individuals not only differ in their predisposition to disease, but also…

    https://www.gesundheitsindustrie-bw.de/en/article/news/intestinal-bacteria-and-human-gut-types
  • Article - 21/05/2012 17201_de.jpg

    Interactions between the genome and the environment

    Parental neglect appears to lead to epigenetic changes in children, which result in behavioural problems in later years. This is one issue amongst the many that were addressed at the colloquium “Gene und Umwelt – Wie wir werden, was wir sind” (Genes and the environment – how we become what we are) recently organized by the Daimler and Benz Foundation in Berlin.

    https://www.gesundheitsindustrie-bw.de/en/article/news/interactions-between-the-genome-and-the-environment
  • Press release - 10/05/2012 Blue strings on black background

    FANCM gene plays key role in inheritance

    Scientists of KIT and the University of Birmingham have identified relevant new functions of a gene that plays a crucial role in Fanconi anemia, a life-threatening disease. The FANCM gene is known to be important for the stability of the genome. Now, the researchers found that FANCM also plays a key role in the recombination of genetic information during inheritance. For their studies, the scientists used thale cress as a model plant. Their…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/fancm-gene-plays-key-role-in-inheritance
  • Article - 16/04/2012 16882_de.jpg

    Endosymbiosis and horizontal gene transfer

    Mitochondria and plastids, which evolved by way of symbiogenesis, have over time come under the control of nuclear genes. It is still not known how the expression of genes encoded in the nucleus and mitochondrion is coordinated to make them functional. Model systems such as highly specialized plastid-incorporating marine slugs can be used to help clarify such issues.

    https://www.gesundheitsindustrie-bw.de/en/article/news/endosymbiosis-and-horizontal-gene-transfer
  • Article - 16/04/2012 The photo shows a blossom with white petals and yellow stamina.

    DNA recombination for targeted plant breeding

    Did evolution invent games of chance? During the development of sperm and egg cells, maternal and paternal genes are mixed at random, thus giving rise to new combinations of traits. What are the molecular mechanisms of this process known as DNA recombination? How can it be used to breed plants with higher yields? Prof. Dr. Holger Puchta and his team at the Karlsruhe Institute of Technology (KIT) are investigating the processes associated with the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/dna-recombination-for-targeted-plant-breeding
  • Press release - 04/04/2012 Insilico Logo Neu

    Insilico on the fast track: Supercomputer breaks into new high performance dimensions

    Starting today, Insilico Biotechnology will use Europe’s very fastest civil computer – going by the name of “Hermit“ – for its modeling and simulating processes. Hermit will cut computing time radically allowing metabolic predictions over several orders of magnitude. In the near future, predictions on the toxic effects of drugs across scales from cellular to organ level will be feasible.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/insilico-on-the-fast-track-supercomputer-breaks-into-new-high-performance-dimensions
  • Press release - 29/03/2012 12629_de.jpg

    GATC Biotech’s NightXpress sequencing service goes Europe-wide

    GATC Biotech, Europe’s leading sequencing provider, now offers its overnight sequencing service NightXpress Europe wide. This unique overnight service has been made possible by the recently opened European Custom Sequencing Centre in Cologne. In Constance, the company’s headquarters, GATC Biotech is building up the European Genome and Diagnostics Centre.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/gatc-biotech-s-nightxpress-sequencing-service-goes-europe-wide
  • Article - 26/03/2012 16790_de.jpg

    More public attention for exotic diseases - Part 1

    An international conference on rare diseases was held in Freiburg Germany in February 2012 where BIOPRO talked with Prof. Dr. Bodo Grimbacher director of the Centre of Chronic Immunodeficiency CCI in Freiburg and Prof. Dr. Maximilian Muenke paediatrician and human geneticist from the National Human Genome Research Institute NHGRI in the USA. Between them the two experts have a great deal of experience in rare diseases amongst other areas. Read in…

    https://www.gesundheitsindustrie-bw.de/en/article/news/more-public-attention-for-exotic-diseases-part-1
  • Article - 26/03/2012 16790_de.jpg

    More public attention for exotic diseases - Part 2

    An international conference on rare diseases was held in Freiburg Germany in February 2012 where BIOPRO talked with Prof. Dr. Bodo Grimbacher director of the Centre of Chronic Immunodeficiency CCI in Freiburg and Prof. Dr. Maximilian Muenke paediatrician and human geneticist from the National Human Genome Research Institute NHGRI in the USA. Between them the two experts have a great deal of experience in rare diseases amongst other areas. Read in…

    https://www.gesundheitsindustrie-bw.de/en/article/news/more-public-attention-for-exotic-diseases-part-2
  • Article - 19/03/2012 16694_de.jpg

    Quantification of the morphology of human blood vessels from 3D tomographic image data

    “QuantVessel”, an innovative approach designed to accurately determine the size and shape of blood vessels from 3D tomographic images, enables vascular diseases to be diagnosed more reliably and makes surgery more effective. The project is being carried out by researchers from the BioQuant centre at Universität Heidelberg and Deutsches Krebsforschungszentrum (German Cancer Research Center) and funded by the German Research Foundation (DFG). It…

    https://www.gesundheitsindustrie-bw.de/en/article/news/quantification-of-the-morphology-of-human-blood-vessels-from-3d-tomographic-image-data
  • Article - 19/03/2012 16705_de.jpg

    Soil bacteria to produce new antibiotics

    An ever-growing number of genomes of soil bacteria of the genus Streptomyces are being sequenced. Using a method known as “genome mining”, researchers at the University of Tübingen are working on the identification of gene clusters that have the potential to be used in industrial biotechnology for the production of new antibiotics and other pharmaceutically active substances. To achieve this, the biosynthesis gene clusters are integrated into…

    https://www.gesundheitsindustrie-bw.de/en/article/news/soil-bacteria-to-produce-new-antibiotics
  • Article - 12/03/2012 16587_de.jpg

    Q-bios provides client-specific biotechnology services

    Q-bios GmbH, a spin-off from the Mannheim University of Applied Sciences, is a biotechnology company that provides services related to the production and purification of diagnostic and therapeutic proteins as well as the development and amplification of suitable cell lines. The company offers its services, which are based on state-of-the-art technologies, to clients from the biotechnology, diagnostic and pharmaceutical industries.

    https://www.gesundheitsindustrie-bw.de/en/article/news/q-bios-provides-client-specific-biotechnology-services
  • Article - 05/03/2012 16575_de.jpg

    Processing of olfactory cues in the brain

    The question as to how the brain produces useful information from the electrical stimuli coming from the sensory organs is a key issue in the neurosciences. Researchers from Heidelberg are investigating how mice discriminate odours and have shown that complex behaviour emerges from the properties of cells and molecules. Using highly specific genetic manipulations for their experiments, the researchers have been able to show that inhibitory…

    https://www.gesundheitsindustrie-bw.de/en/article/news/processing-of-olfactory-cues-in-the-brain
  • Article - 21/02/2012 16512_de.jpg

    How do toxins, viruses and bacteria invade cells?

    For a long time researchers believed that cells more or less invite Trojan Horses to invade them and this is what standard textbooks say. This all changed when Dr. Winfried Römer showed during his postdoctoral period what really happened when toxins invade cells. This has led to new ways of looking at the processes associated with intoxication and the infection of human cells with viruses and bacteria. Today junior professor Dr. Winfried Römer…

    https://www.gesundheitsindustrie-bw.de/en/article/news/how-do-toxins-viruses-and-bacteria-invade-cells
  • Article - 20/02/2012 16326_de.jpg

    "1KITE" project to unravel the evolution of insects

    The large international “1K Insect Transcriptome Evolution” research project aims to construct a robust phylogenetic tree of insects, which is the most species-rich group of organisms. The project aims to study the transcriptomes of 1000 (1K) insect species. The Heidelberg-based Institute for Theoretical Studies provides the software for producing the phylogenetic trees.

    https://www.gesundheitsindustrie-bw.de/en/article/news/1kite-project-to-unravel-the-evolution-of-insects
  • Press release - 01/02/2012 Logo DKFZ, blue letters "DKFZ"

    Defects in the packaging of genetic material in malignant brain tumors

    Glioblastomas are regarded as particularly aggressive brain tumors. In children with glioblastoma, Heidelberg scientists have now discovered genetic alterations that affect the function of DNA packaging proteins known as histones. In a cell, histones serve as coils around which the DNA wraps. At the same time, histones regulate gene activity. Mutations in histone genes have never before been tied to a disease. The group comprising scientists of…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/defects-in-the-packaging-of-genetic-material-in-malignant-brain-tumors
  • Press release - 23/01/2012 16253_de.jpg

    Rigged to explode?

    An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University Hospital, all in Heidelberg, Germany, have discovered. Their study, published online in Cell, also presents the first whole genome sequence of a paediatric…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/rigged-to-explode
  • Article - 16/01/2012 The photo shows fifteen people standing in front of a building.

    Manfred Jung: drug discovery and the epigenetic code

    Prof. Dr. Manfred Jungs team at the University of Freiburg are chemical epigeneticists whose research involves the development of methods that enable them to identify and optimise new therapeutic drugs which are able to alter the epigenetic code of cancer and other cell types. The team use a perfidious worm for their research.

    https://www.gesundheitsindustrie-bw.de/en/article/news/manfred-jung-drug-discovery-and-the-epigenetic-code
  • Article - 19/12/2011 16095_de.jpg

    Daniel Summerer: new ways of biosynthesising proteins with novel functions

    Dr. Daniel Summerer from the University of Konstanz deals with the design of proteins and peptides with novel functions. His approach involves the ribosomal incorporation of unnatural amino acids into proteins with the objective of producing proteins with novel functions in living cells.

    https://www.gesundheitsindustrie-bw.de/en/article/news/daniel-summerer-new-ways-of-biosynthesising-proteins-with-novel-functions
  • Article - 12/12/2011 16001_de.jpg

    Comprehensive Biomarker Center GmbH – next-generation biomarkers

    Biomarker research has moved on from proteins to nucleic acids where one of the main priorities is the use of microRNA expression profiles. The Heidelberg-based biotech company Comprehensive Biomarker Center GmbH (CBC, formerly febit) has state-of-the-art technologies and the skills and knowledge to advance the development of new nucleic acid biomarkers for complex diseases in cooperation with partners from research and industry.

    https://www.gesundheitsindustrie-bw.de/en/article/news/comprehensive-biomarker-center-gmbh-next-generation-biomarkers
  • Dossier - 12/12/2011 16006_de.jpg

    Development of new molecular biomarkers

    Biomarkers are playing an increasing role in drug discovery and development. They can be used as molecular indicators for diseases and disease risks as well as for monitoring the effectiveness of therapy. Highly specific molecular biomarkers are being identified using state-of-the-art technologies from the fields of genomics, proteomics and metabolomics.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/development-of-new-molecular-biomarkers
  • Article - 07/11/2011 15817_de.jpg

    Martin van der Laan and the labyrinth inside mitochondria

    Mitochondria contain an intertwined membrane system that is necessary for the production of energy. Errors in the inner mitochondrial membrane architecture prevent energy from being produced. A group of researchers led by Dr. Martin van der Laan at the University of Freiburg in cooperation with partners has identified a protein complex that plays a key role in the architecture and functioning of the mitochondria.

    https://www.gesundheitsindustrie-bw.de/en/article/news/martin-van-der-laan-and-the-labyrinth-inside-mitochondria
  • Press release - 04/11/2011 15747_de.jpg

    “Junk DNA“ May Give Rise to Evolutionary Innovation

    The vast majority of the human genome consists of DNA without any apparent function so-called junk DNA. A study conducted by the scientists Dr. Laurence Ettwiller and Michael Eichenlaub at Heidelberg Universitys Centre for Organismal Studies COS now highlights this dark matter of the genome as a resource for evolutionary novelty.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/junk-dna-may-give-rise-to-evolutionary-innovation

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