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  • Article - 12/07/2010

    Twelve in one fell swoop – New type 2 diabetes genes

    An international team of scientists working on the largest diabetes study to date have found 12 new diabetes genes in around 140000 Europeans. One of the authors the endocrinologist Bernhard Böhm from Ulm considers the findings to be a breakthrough in the research and treatment of type 2 diabetes.

    https://www.gesundheitsindustrie-bw.de/en/article/news/twelve-in-one-fell-swoop-new-type-2-diabetes-genes
  • Press release - 16/06/2010 11590_de.jpg

    Autism: Variations in Number of Genes Characterize Genome

    The genetic material of autism patients often shows a number of rare genetic alterations. Many genes have variations in the number of copies – they are multiplied or deleted. Several of the affected genes also play a role in other psychiatric developmental disorders. These results have been published by an international research consortium in the latest issue of the science journal Nature. In Germany, scientists of the German Cancer Research…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/autism-variations-in-number-of-genes-characterize-genome
  • Article - 14/06/2010 11507_de.jpg

    Promoters for the construction of genetic circuits

    Gene switches or promoters are crucially important for the regulation of all cellular activities and thus play a pivotal role for researchers constructing externally controllable genetic circuits using synthetic biology methods. The most common artificial regulatory system uses the Tet technology and tetracycline-sensitive promoters invented by Bujard and his team.

    https://www.gesundheitsindustrie-bw.de/en/article/news/promoters-for-the-construction-of-genetic-circuits
  • Article - 14/06/2010 11487_de.jpg

    Mycoplasma bacteria as models for minimal cells

    Bacteria of the genus Mycoplasma are one of the smallest self-replicating cells and serve as model organisms in synthetic biology research for investigating essential life functions as well as being used as chassis for novel, tailor-made biosyntheses. Researchers from Heidelberg are among the groups who focus predominantly on investigating mycoplasma bacteria as minimal organisms.

    https://www.gesundheitsindustrie-bw.de/en/article/news/mycoplasma-bacteria-as-models-for-minimal-cells
  • Dossier - 14/06/2010 11484_de.jpg

    Engineers of life

    Synthetic biology focuses on the development of biological systems with new defined characteristics assembled according to the principles of engineering. Synthetic biology has the potential to be used for a broad range of applications and has solutions in store for major problems of the future. It also fuels fears that human beings are playing the role of creators and going beyond natural boundaries.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/engineers-of-life
  • Press release - 21/05/2010 11414_de.jpg

    The molecular network of “death receptors” on trial

    The international ApoNET research project, which is part of a European-wide systems biology initiative, is coordinated by the Mannheim Medical Faculty at the University of Heidelberg. ApoNET researchers use modern genome sequencing methods and computer models to gain a better understanding of apoptosis networks in liver cells. The project is funded by the German Federal Ministry of Education and Research and the European Union with 1.7 million…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-molecular-network-of-death-receptors-on-trial
  • Article - 10/05/2010 11348_de.jpg

    CeGaT: DNA and RNA sequencing specialist

    Sequencing service providers are facing new challenges due to the enormous technological progress made in this field. The market requires technically feasible solutions reliable and rapid sequence analyses in which entire genomes can be analysed within a couple of days or weeks. This can only be achieved with state-of-the-art high-throughput technologies. Tübingen-based CeGaT GmbH has been offering DNA and RNA sequencing using state-of-the-art…

    https://www.gesundheitsindustrie-bw.de/en/article/news/cegat-dna-and-rna-sequencing-specialist
  • Article - 05/05/2010 11243_de.jpg

    The Hydra genome

    The genome of the freshwater cnidarian Hydra, a model organism used in evo-devo research, was recently deciphered by an international group of researchers including Prof. Thomas Holstein’s group from the University of Heidelberg. The sequencing of the Hydra genome sheds light on the early evolutionary lines and the development of the complexity of multicellular animals.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-hydra-genome
  • Article - 26/04/2010 11204_de.JPG

    PACT Pharmaceuticals – signalling pathways and RNA interference

    In March 2010 PACT Pharmaceuticals the founding concept of Professor Dr. Michael Boutros team at the German Cancer Research Centre was selected as one of ten outstanding business concepts in the Science4Life business plan competition intermediary award. Around 200 business plans were originally submitted. PACT develops innovative cancer therapeutics that target the signalling pathways involved in tumour pathogenesis. PACT develops innovative…

    https://www.gesundheitsindustrie-bw.de/en/article/news/pact-pharmaceuticals-signalling-pathways-and-rna-interference
  • Press release - 23/04/2010 08495_de.jpg

    febit Receives European Union (EU) Patent for Synthesis of Minimal Genomes

    febit announced the receipt of an EU patent EP 1 728 860B1 for its technology to synthesize minimal genomes. The new patent protects febits technology for combining genes to construct a minimal functional genome or parts of it. The EU patent complements earlier patents on the synthesis of oligonucleotides for gene-assembling.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/febit-receives-european-union-eu-patent-for-synthesis-of-minimal-genomes
  • Press release - 23/04/2010 Logo DKFZ, blue letters "DKFZ"

    International Cancer Genome Project Publishes Article in Nature

    Information obtained in the various projects of the International Cancer Genome Consortium may soon be used to the benefit of cancer patients worldwide because the data will be freely accessible and not patentable. The project thus aims to make sure that the molecular data of the various tumor types can be used as swiftly as possible for new diagnostic methods or therapies.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/international-cancer-genome-project-publishes-article-in-nature
  • Press release - 20/04/2010 Portrait of professor doctor Heinz Schaller

    The ZMBH mourns the death of Heinz Schaller

    The Centre for Molecular Biology at the University of Heidelberg ZMBH is in mourning following the death of Prof. Dr. Heinz Schaller at the age of 78 on April 10 2010 after a short illness. Heinz Schaller was not only the driving force behind the foundation and development of the ZMBH at the University of Heidelberg he was also one of the founding fathers of molecular biological research and molecular virology in Germany. His scientific…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-zmbh-mourns-the-death-of-heinz-schaller
  • Article - 19/04/2010 The microscope image shows six spherical structures closely attached to each other.<br />

    Trying to get a virus to reveal its tricks

    The Thogoto virus is an exotic virus that presents virtually no danger to humans. A group of virologists led by Prof. Dr. Georg Kochs at the Freiburg University Medical Centre are using the virus as model system for its particular suitability in certain experiments. The group is investigating how the virus evades the antiviral defence of the infected host.

    https://www.gesundheitsindustrie-bw.de/en/article/news/trying-to-get-a-virus-to-reveal-its-tricks
  • Press release - 09/04/2010

    Next-generation sequencing to advance research at the Mannheim Medical Faculty

    Scientists of the Department of Cell and Molecular Biology at the Mannheim Medical Faculty of the University of Heidelberg are to benefit from access to cutting-edge sequencing technology. The next-generation sequencer is the first of its kind at the University of Heidelberg.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/next-generation-sequencing-to-advance-research-at-the-mannheim-medical-faculty
  • Press release - 17/03/2010 European Molecular Biology Laboratory

    Bacterial balance that keeps us healthy

    Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, working within the European project MetaHIT and in collaboration with colleagues at the Beijing Genomics Institute at Shenzhen, China, established a reference gene set for the human gut microbiome – a catalogue of the microbe genes present in the human gut. Their work proves that high-throughput techniques can be used to sequence environmental samples, and…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/bacterial-balance-that-keeps-us-healthy
  • Article - 15/03/2010 10212_de.jpg

    Cornelia Ulrich: Cancer prevention through food and sports

    The appointment of Cornelia Ulrich as professor and head of the Departments of Preventive Oncology at the National Centre for Tumour Diseases and the German Cancer Research Centre shows that Heidelberg is expanding its research priorities in the prevention and early diagnosis of cancer. Ulrichs main focus has been on the folic acid metablism C1 compounds and inflammation.

    https://www.gesundheitsindustrie-bw.de/en/article/news/cornelia-ulrich-cancer-prevention-through-food-and-sports
  • Article - 13/03/2010 10874_de.jpg

    Assembling life from building blocks?

    As part of its “Bioethics Forum”, the German Ethics Council recently held a meeting in Berlin to inform the public about the fundamentals of synthetic biology and potential ethical problems and consequences in terms of our ideas about life and mankind in general arising from the progress made in this new field of research.

    https://www.gesundheitsindustrie-bw.de/en/article/news/assembling-life-from-building-blocks
  • Press release - 09/03/2010 Insilico Logo Neu

    Insilico: co-designer of innovative cell factory for fine chemicals

    A new BMBF joint project to transfer systems biology research directly into practical applications is profiting from Insilico Biotechnology’s expertise. The goal is to make Pseudomonas bacterial strains fit for commercial use in the field of industrial biocatalysis. The project will run for three years, coordinated by BASF and financed with approx. EUR 5.5 million. Insilico Biotechnology is the second partner from industry, while all others are…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/insilico-co-designer-of-innovative-cell-factory-for-fine-chemicals
  • Press release - 04/03/2010 10810_de.jpg

    New German-Austrian project for breast cancer therapy

    Hope for breast cancer patients under the leadership of the Vorarlberg Institute for Vascular Investigation and Treatment VIVIT a cross border cooperation is to start between hospitals and bioanalytical laboratories of the Rhine Valley and Lake Constance region. It is aimed at exploring the influence genetic material DNA has on the progression of breast cancer and the response to breast cancer treatment. A collaboration which became possible…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-german-austrian-project-for-breast-cancer-therapy
  • Press release - 16/02/2010 Logo DKFZ, blue letters "DKFZ"

    He Who Dares Wins – Million Euro Funding for DKFZ Researcher

    The European Research Council will provide funding of 2.4 million euro over the next four years to support a research project of Christof Niehrs at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ). Niehrs investigates the processes of reactivation of silenced genes in cells. Disruption of this mechanism can cause cancer and other diseases.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/he-who-dares-wins-million-euro-funding-for-dkfz-researcher
  • Article - 11/02/2010 The photo shows a pink bubble with lilac spots against a black background. Green spots are scattered around the pink bubble.

    The complexities of signal transduction

    Ten years ago, cellular signalling was a simple and straightforward process. Nowadays, what once seemed so simple is riddled with complexities. Dr. Tilman Brummer and his team at the Centre for Biosystems Analysis (ZBSA) in Freiburg are investigating the complex molecular interactions sparked off by signals inside cells. They are especially interested in the signalling network involving the protein Raf. Faults in the dynamic processes involving…

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-complexities-of-signal-transduction
  • Press release - 04/02/2010 10452_de.jpg

    MicroRNA: a glimpse into the past

    Scientists at the European Molecular Biology Laboratory EMBL in Heidelberg Germany have discovered that microRNAs are found in the exact same tissues in animals as diverse as sea anemones worms and humans hinting at an early origin of these tissues in animal evolution.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/microrna-a-glimpse-into-the-past
  • Press release - 04/02/2010 German Cancer Research Centre

    Signalling pathway in cancer cells needs acid: new targets for tailor-made therapies?

    The Wnt signalling pathway plays an important role in embryonic development, in stem cells and also in diseases such as cancer. Some of the individual steps of this signalling pathway are not yet known in detail including in particular the mechanism by which the Wnt protein activates the Wnt receptor during binding. Scientists from the German Cancer Research Centre (Deutsches Krebsforschungszentrum, DKFZ) have now made a substantial contribution…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/signalling-pathway-in-cancer-cells-needs-acid-new-targets-for-tailor-made-therapies
  • Press release - 02/02/2010 GATC Biotech AG Logo

    GATC Biotech orders Europe’s first HiSeq 2000 for commercial use

    GATC Biotech today announced the purchase of Illumina’s new HiSeq 2000 sequencing platform, which has officially been launched last week. This latest acquisition will further strengthen GATC Biotech’s current fleet of three GA IIx.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/gatc-biotech-orders-europe-s-first-hiseq-2000-for-commercial-use
  • Dossier - 01/02/2010 The photos shows a young boy with enlarged abdomen, which is a major symptome of congenital Gaucher's disease.

    Metabolic diseases

    Metabolic diseases are characterised by disorders of the intermediary metabolism which can either be inherited or acquired. The extent and incidence of metabolic diseases can differ considerably and can range from widespread diseases such as diabetes to rare congenital diseases that frequently have a fatal outcome. Through new approaches in genome research amongst other things science and industry are increasingly focusing on metabolic diseases.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/metabolic-diseases

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