Press release - 04/11/2011 Alternate ending – living on without telomerase Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes. https://www.gesundheitsindustrie-bw.de/en/article/press-release/alternate-ending-living-on-without-telomerase
Article - 17/10/2011 Papillomaviruses as cancer-causing agents and how they can be fought off Studies presented at the recent International Papillomavirus Conference in Berlin demonstrate that vaccination can prevent infection with the types of HPV that cause the majority of cervical cancers. New improved vaccines to prevent HPV infections as well as therapeutic vaccines that are effective in people that are already infected are currently being developed. In addition, research has shown that other cancers can also be caused by infective…https://www.gesundheitsindustrie-bw.de/en/article/news/papillomaviruses-as-cancer-causing-agents-and-how-they-can-be-fought-off
Article - 18/09/2011 BMBF project AllerGen: DNA test to protect consumers against food allergens People who are hypersensitive to a particular food protein can develop an adverse reaction to the smallest amount of the allergenic protein that can range from mild to severe. Although many allergic people are aware of their hypersensitivity to certain food proteins they can have allergic reactions because they are not always aware of the presence of allergenic proteins in certain food products. This is why the reliable sensitive and quantitative…https://www.gesundheitsindustrie-bw.de/en/article/news/bmbf-project-allergen-dna-test-to-protect-consumers-against-food-allergens
Article - 12/09/2011 How snails can survive heat Professor Dr. Heinz-R. Köhler and Professor Dr. Rita Triebskorn two zoologists from the University of Tübingen are working with research teams from Avignon Esslingen Gießen and Le Havre to investigate how snails are able to adapt to extreme climatic conditions on the molecular cellular and physiological level. Their Hot Snail project is funded by the German Research Foundation DFG and its particular objective is to find out whether reactions to…https://www.gesundheitsindustrie-bw.de/en/article/news/how-snails-can-survive-heat
Article - 12/09/2011 Claudia Stürmer: the growth and regeneration of nerve fibres Axons are the long, slender projections of nerve cells whose growth is governed by the intrinsic properties of neurons as well as by growth-promoting and growth-inhibiting molecules present in the neurons’ environment. In fish, the injured axons of the central nervous systems are able to regenerate. This is not the case in mammals, and therefore humans. A group of researchers led by Prof. Dr. Claudia Stürmer at the University of Konstanz is…https://www.gesundheitsindustrie-bw.de/en/article/news/claudia-stuermer-the-growth-and-regeneration-of-nerve-fibres
Article - 22/08/2011 Jörg Overhage investigates how bacteria react to stress Bacteria have been around for a very long time and they will probably still be around in the future. They are able to adapt to any factor that is potentially fatal to cells heat hunger radiation toxic chemicals or immune attacks. However tolerance to stress is not only characteristic of individual bacteria bacteria join forces whenever inhospitable conditions arise. A team of researchers led by Dr. Jörg Overhage at the Karlsruhe Institute of…https://www.gesundheitsindustrie-bw.de/en/article/news/joerg-overhage-investigates-how-bacteria-react-to-stress
Dossier - 22/08/2011 Stress and molecular defence mechanisms Organisms can experience stress from exposure to bacteria and pathogenic fungi; in fact, stress can arise from exposure to any type of environmental influence. As they have evolved, biological cells have developed numerous molecular mechanisms that enable them to survive even in inhospitable conditions. What kind of effects do abiotic stress factors have on plants and human beings? How do cells protect themselves? Are researchers able to increase…https://www.gesundheitsindustrie-bw.de/en/article/dossier/stress-and-molecular-defence-mechanisms
Press release - 29/07/2011 The brain’s connectome – from branch to branch The human brain is the most complex of all organs, containing billions of neurons with their corresponding projections, all woven together in a highly complex, three-dimensional web. To date, mapping this vast network posed a practically insurmountable challenge to scientists. Now, however, a research team from the Heidelberg-based Max Planck Institute for Medical Research has developed a method for tackling the mammoth task. Using two new…https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-brain-s-connectome-from-branch-to-branch
Article - 25/07/2011 Christian Thoma – the control of translation enables the rapid regulation of cellular processes Heisenberg fellow PD Dr. Christian Thoma from the Freiburg University Medical Centre has been focusing on the regulation of translation for a number of years and has established a method that enables him to investigate translation on the molecular level. Thoma and his team have come a step closer to their goal of finding targets for the therapy of cancer and hepatitis C.https://www.gesundheitsindustrie-bw.de/en/article/news/christian-thoma-the-control-of-translation-enables-the-rapid-regulation-of-cellular-processes
Article - 04/07/2011 Stefan Rensing investigates the evolutionary transition from algae to land plants The biologist Prof. Dr. Stefan Rensing from the University of Freiburg has been involved in introducing the use of computers to the life sciences from the very beginning. His analyses of the moss genomes now help to close an important gap in evolutionary research how did algae become land plants?https://www.gesundheitsindustrie-bw.de/en/article/news/stefan-rensing-investigates-the-evolutionary-transition-from-algae-to-land-plants
Press release - 30/06/2011 Cancer treatments: New information from fission yeast When a cell divides the genetic information in the chromosomes must be passed on error-free to the daughter cells. Researchers at the Friedrich Miescher Laboratory in Tübingen are studying this process using fission yeast as a model organism. In cooperation with researchers at the University of Tübingen they succeeded in attributing additional tasks to the Aurora enzymes which were already recognized as important cellular tools for the reliable…https://www.gesundheitsindustrie-bw.de/en/article/press-release/cancer-treatments-new-information-from-fission-yeast
Article - 27/06/2011 The EURAT project at the Marsilius Kolleg in Heidelberg Bioinformaticians, human geneticists, molecular biologists, oncologists, pathologists, lawyers and theologians are all participating in the project “Ethical and legal aspects of the total sequencing of the human genome” (EURAT) being carried out at Heidelberg University’s Marsilius Kolleg. The project partners are developing a common viewpoint and working out solutions for problems arising from the possibilities of total genome sequencing. https://www.gesundheitsindustrie-bw.de/en/article/news/the-eurat-project-at-the-marsilius-kolleg-in-heidelberg
Article - 20/06/2011 Molecular biologists to celebrate 50th anniversary of Jacob and Monod’s operon model Leading molecular biologists from around the world came together at a conference jointly organized by the European Molecular Biology Organisation (EMBO) and the Institut Pasteur in Paris between 17th and 20th May to celebrate the 50th anniversary of the operon concept published by François Jacob and Jacques Monod in 1961. The scientists discussed concepts and research results influenced by the operon model, which have led to our present…https://www.gesundheitsindustrie-bw.de/en/article/news/molecular-biologists-to-celebrate-50th-anniversary-of-jacob-and-monod-s-operon-model
Article - 06/06/2011 Review: “DKFZ-ZMBH Alliance Forum on Aging & Cancer” in Heidelberg At the DKFZ-ZMBH Alliance Forum 2011 recently held in Heidelberg internationally leading molecular and cell biologists cancer researchers and epidemiologists presented their latest results on the ageing of cells and organisms and the development of cancer.https://www.gesundheitsindustrie-bw.de/en/article/news/review-dkfz-zmbh-alliance-forum-on-aging-cancer-in-heidelberg
Press release - 23/05/2011 Systems biology in Baden-Württemberg The emerging interdisciplinary field of systems biology is pursuing a completely new approach namely the description of the dynamic interplay of all the components of a biological system using mathematical models with the aim of obtaining a holistic view of the system under consideration. This new approach is expected to lead to new approaches for the treatment of diseases and for the industrial production of enzymes. With its three systems…https://www.gesundheitsindustrie-bw.de/en/article/press-release/systems-biology-in-baden-wuerttemberg
Article - 02/05/2011 Production of high-density peptide arrays Frank Breitling and Alexander Nesterov-Müller from the Karlsruhe Institute of Technology KIT are working on the development of a second-generation peptide laser printer and a peptide chip printer based on computer chips. This development will enable the low-cost production of high-density peptide arrays consisting of up to one million peptides as well as opening up completely new areas of application.https://www.gesundheitsindustrie-bw.de/en/article/news/production-of-high-density-peptide-arrays
Article - 30/04/2011 The DKFZ-ZMBH Alliance The strategic alliance between the cell and tumour biology research priority at the German Cancer Research Center and the Center for Molecular Biology at Universität Heidelberg has led to the development of one of the largest centres of basic biomedical research in Germany. The top international profile of this interdisciplinary institution located at the interface between molecular and cellular biology tumour biology and biomedicine is reflected…https://www.gesundheitsindustrie-bw.de/en/article/news/the-dkfz-zmbh-alliance
Press release - 20/04/2011 Successful pilot study for non-invasive prenatal diagnostic test to determine trisomy 21 Scientists from the Center for Prenatal Diagnosis and Human Genetics, Kudamm-199, in Berlin have been working with scientists from GATC Biotech AG and LifeCodexx AG to develop a non-invasive diagnostic test based on Next Generation Sequencing which reliably detects a fetal trisomy 21 (Down syndrome).https://www.gesundheitsindustrie-bw.de/en/article/press-release/successful-pilot-study-for-non-invasive-prenatal-diagnostic-test-to-determine-trisomy-21
Article - 04/04/2011 FreiBiotics GmbH – new drugs against resistant bacteria Bacteria adapt quickly to their environment and also to antibiotics. Many of the antibiotics used to treat bacterial infections have become ineffective as a great many bacteria have become resistant to them. Freiburg-based FreiBiotics GmbH is looking for completely new classes of antimicrobial substances. A screening method that has been developed over the last few years based on biosensors makes the identification of new substance classes more…https://www.gesundheitsindustrie-bw.de/en/article/news/freibiotics-gmbh-new-drugs-against-resistant-bacteria
Article - 21/03/2011 Andrea Hartwig – trace elements, toxic metals and the thin line in between For more than 25 years Prof. Dr. Andrea Hartwig has been investigating the quantities of metal compounds that have a beneficial or toxic effect on human health. As a basic researcher the new chair of the Department of Food Chemistry and Toxicology at the Karlsruhe Institute of Technology KIT has managed to clarify many mechanisms of action of toxic metals including on the molecular level.https://www.gesundheitsindustrie-bw.de/en/article/news/andrea-hartwig-trace-elements-toxic-metals-and-the-thin-line-in-between
Press release - 09/03/2011 DKFZ and IBM have signed a collaboration agreement on cancer genome analysis The International Cancer Genome Project analyzes the complete genomes of thousands of cancer patients. This generates enormous amounts of data. To find those gene segments which are pivotal for cancer development and treatment, intelligent IT systems are needed. The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg and IBM have signed a strategic partnering agreement at CeBIT 2011. The aim of the agreement is to…https://www.gesundheitsindustrie-bw.de/en/article/press-release/dkfz-and-ibm-have-signed-a-collaboration-agreement-on-cancer-genome-analysis
Press release - 28/02/2011 Heidelberg "start-up" wins the German Industry’s Innovation Award 2010 PEPperPRINT GmbH has won the 2010 German Industry’s Innovation Award in the category “Start-Up Companies”. The Heidelberg-based biotechnology company was awarded the prize by the German Minister of Education and Research, Dr. Annette Schavan, at a German industry festive event recently held in the Frankfurt Congress Centre. https://www.gesundheitsindustrie-bw.de/en/article/press-release/heidelberg-start-up-wins-the-german-industry-s-innovation-award-2010
Article - 14/02/2011 Comprehensive data analysis as the basis for individualised drugs Individual patients metabolise certain drugs in very different ways some patients metabolise drugs well and others do not respond at all. The difference in individual patients ability to metabolise drugs depends not only on environmental influences but also on genetic factors which means that the sequencing of the human genome has become a major prerequisite for the application of personalised medicine. In the following interview Dr. Jens…https://www.gesundheitsindustrie-bw.de/en/article/news/comprehensive-data-analysis-as-the-basis-for-individualised-drugs
Press release - 09/02/2011 The human genome’s breaking points A detailed analysis of data from 185 human genomes sequenced in the course of the 1000 Genomes Project, by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with researchers at the Wellcome Trust Sanger Institute in Cambridge, UK, as well as the University of Washington and Harvard Medical School, both in the USA, has identified the genetic sequence of an unprecedented 28.000 structural…https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-human-genome-s-breaking-points
Article - 07/02/2011 The discovery of the individual as business model The move towards personalised medicine has made considerable progress, in particular in the field of oncology, where it is leading to the close integration of diagnostics and therapy as well as to the development of profitable new business models, some of which have controversial exclusive legal claims.https://www.gesundheitsindustrie-bw.de/en/article/news/the-discovery-of-the-individual-as-business-model