Experts in Heidelberg have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more than 100 molecular subtypes of central nervous system tumors, delivers results within minutes, and could accelerate the diagnosis of brain tumors worldwide.

In rare cases, cancer treatments can cause serious long-term effects. These include so-called secondary leukemias. This form of blood cancer can develop when chemotherapy or radiotherapy damages the genetic material of healthy cells. A research team led by a scientist from Ulm has now discovered a molecular protective mechanism against such genomic damage: a peptide.

The German Chemical Industry Fund (FCI) is supporting the course offering ‘DigiChemJN’ at the Faculty of Chemistry and Pharmacy. DigiChemJN strengthens students’ data literacy by providing them qualifications in data-based research methods, experimental datasets, and artificial intelligence (AI).

How do antimetabolite cancer drugs damage the genetic material of malignantly transformed cells and thereby destroy them? How might these drugs be used more precisely, particularly in the treatment of pediatric tumors? A new research group led by Dr. Christopher Carnie, a scientist at the Heidelberg Faculty of Medicine at Heidelberg University, will address these questions.

Living systems such as cells rely on membrane pores and channels to transport molecules, exchange signals, and organize biochemical reactions. These functions emerge from dynamic interactions between molecular components. Researchers at the University of Stuttgart have used DNA nanotechnology to develop a synthetic membrane architecture that mimics such interactions.

The life science group Sartorius has opened a new center in Freiburg, Germany, dedicated to the development and production of quality-critical materials for the cell and gene therapy market. In Freiburg, the company manufactures essential components such as cytokines and growth factors used in these novel therapies. With an investment of more than 140 million euros, Sartorius is reaffirming its strategic focus on this emerging business area.

Medical Center – University of Freiburg demonstrates a fundamental therapeutic approach for hereditary immune system defects in a mouse model. The safety profile of genome editing varies significantly depending on the method and cell type.

AI is transforming science and does not stop at neuroscience. In this interview, we speak to Gabriele Lohmann about her research at the intersection of the brain and algorithms. She talks about the use of artificial intelligence as a research tool, the decoding of brain activity, and why large language models do not understand what they are doing.

Led by researchers from Heidelberg Faculty of Medicine at Heidelberg University and the University of California, San Francisco (USA), an international research team has evaluated a novel approach for the diagnosis of pulmonary tuberculosis. The method enables detection of Mycobacterium tuberculosis without laboratory infrastructure, within a markedly shorter time frame than conventional diagnostics, and using a simple swab.

Ulm University held an awards ceremony to recognise the outstanding achievements in research and teaching of its early-career researchers. The event, held at the end of April at Villa Eberhardt, focused on researchers who had received seed funding for their own research projects.

Genome duplication probably gave biodiversity a decisive evolutionary boost. A Chinese-German research team led by Axel Meyer from the University of Konstanz has now investigated the early phases of the process known as re-diploidization. The results show that the fusion of chromosome sets is asynchronous.

A novel biomimetic tissue substitute combines precisely tunable mechanical properties with biological functionality and is now ready for applications in medical technology. The material was developed in the »PolyKARD« project by Fraunhofer IAP and the NMI Natural and Medical Sciences Institute. From 20.-24.04, 2026, the material will be presented together with further developments at the Hannover Messe, Fraunhofer joint booth.

How can you charge electric cars without plugging them into the power grid for hours on end? How can industrial robots be “refueled” during operation? And how does wireless energy transfer improve medical technology? These questions have occupied Prof. Nejila Parspour, Director of the Institute of Electrical Energy Conversion (IEW) at the University of Stuttgart, for more than twenty years.

Computer simulations and Artificial Intelligence are the main pillars of the “SIMPLAIX” collaboration, initiated by the Heidelberg Institute for Theoretical Studies (HITS). Together with colleagues from Heidelberg University and Karlsruhe Institute of Technology, HITS researchers are addressing challenges in the simulation of biomolecules and molecular materials by pooling their expertise in multiscale computer simulation and machine learning.

Computer simulations and Artificial Intelligence are the main pillars of the “SIMPLAIX” collaboration, initiated by the Heidelberg Institute for Theoretical Studies (HITS). Together with colleagues from Heidelberg University and Karlsruhe Institute of Technology, HITS researchers are addressing challenges in the simulation of biomolecules and molecular materials by pooling their expertise in multiscale computer simulation and machine learning.

The Volkswagen Foundation is supporting the Ulm scientist Professor Walter Karlen with more than 940,000 euros from the funding initiative "Momentum - funding for first-time researchers". The engineer has headed the Institute of Biomedical Engineering at Ulm University since 2021. Karlen conducts research in the field of mobile health on so-called Medicine Wearables, i.e. portable technology for recording health data.

Proof-of-concept study of organoid technology - 26/03/2026

Can organoids improve the treatment of pancreatic cancer?

A clinical trial called UNITEPANC is exploring whether organoid-based approaches can improve the treatment of pancreatic cancer. BIOPRO Baden-Württemberg spoke with the study’s principal investigator and pancreatic cancer specialist, Prof. Dr. Thomas Seufferlein of University Hospital Ulm, to discuss the disease more broadly along with the specific aims of the trial. The interview was conducted by Walter Pytlik on behalf of BIOPRO.

The powerhouse of the cells, known as mitochondria, appear to be able to influence the number of lipid droplets in the cell. Research into this previously unknown mechanism was conducted using baker’s yeast. This is shown by a recent study by the University of Freiburg, the University of Bonn and the University Hospital Bonn and the University of Freiburg. The results have now been published in the journal Nature Cell Biology.

In a published scientific study, researchers have succeeded in accurately diagnosing common types of brain tumors in children and adolescents based on tumor-derived genetic material in cerebrospinal fluid. Until now, these so-called liquid biopsies were not capable enough for such reliable diagnostics. The international research team has therefore optimized a sequencing technique and developed an AI-based computational method. In a later step,…

In a joint study conducted by the DZHK sites in Heidelberg, Munich and Göttingen, researchers are deciphering how the spatial organisation of the genome in the heart determines genetic disease risks.

How modern medical technology can prevent serious consequences of surgical procedures is demonstrated by a recent internationally recognized scientific publication. The study “Validation of conductive resin as electrode material in neuromonitoring with 3D-printed probes” under the leadership of Drs. Kiese and Bucher was awarded at the ICST Conference in Japan and highlights a medical topic that is crucial for the quality of life of many people.

Researchers at the Hopp Children's Cancer Center Heidelberg, the German Cancer Research Center, the Heidelberg Medical Faculty of Heidelberg University, and Heidelberg University Hospital have taken a decisive step toward more precise diagnosis of brain tumors. The latest version of the AI-based Heidelberg CNS Tumor Methylation Classifier can identify more than 180 tumor types —twice as many as the previous version.

The technology company KyooBe Tech GmbH and the German Center for Infection Research (DZIF) have signed a memorandum of understanding to collaborate on future research and development projects. The aim of the collaboration is to evaluate an innovative technology for inactivating pathogens using the specific effect of low-energy accelerated electrons (Low Energy Electron Irradiation—LEEI) and to make it available to DZIF scientists.

At the new Institute for Adaptive Mechanical Systems (IAMS) at the University of Stuttgart, the focus is on a new generation of walking robots and “soft robotics”. The researchers are developing adaptable robots inspired by natural movement patterns and made from innovative soft materials. The applications range from healthcare and industrial production to energy supply.

LICIT Solutions completes Series A financing to accelerate the development and commercialization of next-generation sustainable active ingredients for hygiene, preservation, and protective applications LICIT Solutions GmbH, a spin-out from the Institute for Clinical Anatomy and Cell Analysis at the University of Tübingen, has successfully completed its Series A financing round.