Article - 27/08/2012 Cardiac or intestinal progenitor cells? What controls the fate of pluripotent stem cells? Cell fate decisions are made in the early mouse embryo when it is nothing more than a spherical mass of cells. A molecule known as eomesodermin determines whether pluripotent stem cells become cardiac or intestinal progenitor cells. Dr. Sebastian Arnold and his research group at the Freiburg University Medical Centre have recently discovered why one single molecule can have a twofold effect. These findings provide Arnold and his team with greater…https://www.gesundheitsindustrie-bw.de/en/article/news/cardiac-or-intestinal-progenitor-cells-what-controls-the-fate-of-pluripotent-stem-cells
Article - 13/12/2008 Insights into the perception of light Rhodopsin mediates between the visual world and our brain. Biophysicists at Freiburg have used infrared spectroscopy to gain detailed insights into the rhodopsin centre to find out how the molecular side chains of the proteins have to interact in order for the brain to understand the visual environment. https://www.gesundheitsindustrie-bw.de/en/article/news/insights-into-the-perception-of-light
Article - 20/06/2011 How plants change their shape – researchers at KIT investigate cytoskeletal processes Organisms have two possibilities when they encounter inhospitable environmental conditions: to run away or to adapt. As plants have no legs, they therefore need to adapt rapidly to unstable environmental conditions. A plant is hugely flexible in terms of its shape and one of the things that makes this possible is its cytoskeleton, a scaffold consisting of specialized filaments. A group of researchers at the Karlsruhe Institute of Technology (KIT)…https://www.gesundheitsindustrie-bw.de/en/article/news/how-plants-change-their-shape-researchers-at-kit-investigate-cytoskeletal-processes
Article - 25/06/2012 The physiological importance of the Alzheimer protein While the role of the amyloid precursor protein (APP) in the development of amyloid plaques that are characteristic of Alzheimer’s disease is well known, the physiological role of this protein in the brain has remained elusive. However, the molecular biologist Professor Dr. Ulrike Müller from Heidelberg has now shown in mouse models that components of the APP gene family play a major role in synaptic plasticity, learning and memory. https://www.gesundheitsindustrie-bw.de/en/article/news/the-physiological-importance-of-the-alzheimer-protein
Article - 18/11/2013 The HAE Accelerator – "compete to speed up your start-up" The HAE Accelerator is an international programme involving biomedical clusters in Cambridge (UK), Leuven (Belgium) and Heidelberg (Germany) that seeks to identify, train and put innovative start-up teams in the three countries in contact with international VC investors. Of the three business ideas that were awarded a HAE Investors’ Choice Award in September 2013, InoCard from Heidelberg came first with a new gene therapy for myocardial…https://www.gesundheitsindustrie-bw.de/en/article/news/the-hae-accelerator-compete-to-speed-up-your-start-up
Article - 17/10/2011 Aristides Arrenberg uses light to investigate the working memory Dr. Aristides Arrenberg from the University of Freiburg did his doctorate in the USA where he further developed a method that can be used to silence or activate specific zebrafish nerve cells at will. The method is based on light stimuli that trigger cellular switches. In addition the researchers have recently published an article on research into how eye movements are stored in the hindbrain. Standard network models used for so-called integrator…https://www.gesundheitsindustrie-bw.de/en/article/news/aristides-arrenberg-uses-light-to-investigate-the-working-memory
Article - 12/05/2016 Novel method for predicting the spatial structure of biomolecules Biomolecules can only fulfil their functions in the cell when they fold into a characteristic native three-dimensional structure. Knowing this structure is not only of paramount importance for basic research, but also for medicine and pharmacology. Scientists from the Karlsruhe Institute of Technology (KIT) have therefore developed a simple method to predict the three-dimensional structure of biomolecules from the analysis of readily available…https://www.gesundheitsindustrie-bw.de/en/article/news/novel-method-for-predicting-the-spatial-structure-of-biomolecules
Article - 22/07/2013 Marcus Fändrich strengthens protein biochemistry at Ulm University After quite a long vacancy the directors post of the Institute for Pharmaceutical Biotechnology at the University of Ulm has finally been filled. Marcus Fändrich and his team moved into the laboratories and offices of the new life sciences building on the Oberer Eselsberg Ulm University campus in November 2012. Fändrich fills a gap in the Ulm Bioregions biopharmaceutical education activities as he will not only be teaching biochemistry…https://www.gesundheitsindustrie-bw.de/en/article/news/marcus-faendrich-strengthens-protein-biochemistry-at-ulm-university
Dossier - 03/07/2008 Molecular imaging - a close look inside the human body Molecular imaging recognises the functional state of cells and molecules. It visualises biological processes on the cellular and molecular level and is thus able to detect pathological alterations a long time before disease symptoms become apparent. Molecular imaging offers new possibilities for improving diagnosis and enabling more targeted therapies than has previously been possible. Many experts regard molecular imaging as a paradigm shift in…https://www.gesundheitsindustrie-bw.de/en/article/dossier/molecular-imaging-a-close-look-inside-the-human-body
Press release - 20/05/2008 Bookmarks in the human book of life Histone acetyltransferases HATs and their antagonists the histone deacetylases are important enzymes in epigenetic gene regulation. Scientists discovered new HAT inhibitors that are now being investigated for their potential as anti-cancer drugs.https://www.gesundheitsindustrie-bw.de/en/article/press-release/bookmarks-in-the-human-book-of-life
Article - 19/12/2011 Wolfgang Rottbauer discovers zebrafish for use in cardiology Zebrafish is a popular model organism for many researchers around the world. Life scientists such as evolutionary biologists, neurobiologists and toxicologists frequently use the small vertebrate for their investigations. Wolfgang Rottbauer has discovered and established the zebrafish as a model organism for cardiovascular disease research. He has also made a name for himself in this field. However, Rottbauer recalls that his efforts were…https://www.gesundheitsindustrie-bw.de/en/article/news/wolfgang-rottbauer-discovers-zebrafish-for-use-in-cardiology
Article - 02/05/2016 Biopolymers – raw materials for innovative medical products Polyhydroxyalkanoates (PHA) are biodegradable biopolymers that are becoming increasingly important. Bioplastics are now used not only in everyday objects such as plastic bags and yogurt pots but also increasingly in the field of medicine, which is why intensive research into medical devices made from biodegradable polymers such as PHA has been going on for quite some time. https://www.gesundheitsindustrie-bw.de/en/article/news/biopolymers-raw-materials-for-innovative-medical-products
Article - 21/02/2019 Using neuromedical artificial intelligence responsibly Brain-computer interfaces are the latest developments in the neurotechnology field. They are used to record brain activity, which is then decoded with artificial intelligence techniques and converted into control signals for robots or computers. While this brings hope to severely paralysed people, it also implies risks due to the interest of companies like Google and Facebook in this type of data.https://www.gesundheitsindustrie-bw.de/en/article/news/using-neuromedical-artificial-intelligence-responsibly
Article - 24/10/2009 Molecular switches for gene expression in the embryo Prof. Dr. Andreas Hecht and his team at the University of Freiburg are investigating one of seven known fundamental signalling systems that are involved in almost all embryonic development processes and that determine the fate of cells. The scientists are mainly interested in gaining insights into why the same molecules initiate different genetic programmes and hence development pathways depending on the cell type where they have their effect.https://www.gesundheitsindustrie-bw.de/en/article/news/molecular-switches-for-gene-expression-in-the-embryo
Article - 03/09/2009 The lipid metabolism and the immune system What has the lipid metabolism of the human body got to do with inflammation? Scientists in Dr. Petra May’s group at the Centre for Neuroscience at the University of Freiburg recently found that molecules which normally regulate the availability of cholesterol and other water-insoluble substances, also interact with the signalling networks of the immune system. According to their findings, a receptor which mediates the uptake of certain…https://www.gesundheitsindustrie-bw.de/en/article/news/the-lipid-metabolism-and-the-immune-system
Article - 21/04/2008 Human blood system in mice Scientists from Mannheim Heidelberg an Freiburg working together in the cooperative research area Vascular Biology have developed a method that can be used to create a human vascular system in mice which stays functional even after several months.https://www.gesundheitsindustrie-bw.de/en/article/news/human-blood-system-in-mice
Article - 03/04/2019 HKK Bionics empowers hand gripping functions A spin-off from the Ulm University of Applied Sciences is aiming to provide people whose hands have been paralysed due to accident or illness with a new kind of orthopaedic aid. Dominik Hepp and Tobias Knobloch are currently starting serial production of a hand orthosis prototype. The two medical engineers from Ulm, who founded HKK Bionics GmbH in 2017, plan to commence final tests in 2019.https://www.gesundheitsindustrie-bw.de/en/article/news/hkk-bionics-empowers-hand-gripping-functions
Article - 03/12/2012 DFG strengthens Ulm research into ageing with new research training group The German Research Foundation (DFG) has recently granted Ulm University funding for a research training group (RTG) into ”Cellular and Molecular Mechanisms of Ageing”. This again confirms the strength of ageing research at Ulm University. The granting of funds totalling three million euros over a period of four and a half years is an important indication of the continued strength of the small university, particularly as many were worried that…https://www.gesundheitsindustrie-bw.de/en/article/news/dfg-strengthens-ulm-research-into-ageing-with-new-research-training-group
Article - 04/03/2013 TellTargeting Medical GmbH – targeted chemotherapy using CARL® The needs of cancer patients are clear chemotherapies that are as gentle as possible associated with minimal adverse effects and have a rapid effect. This is often difficult to achieve because the drug that stops tumour growth needs to remain in the body for a certain amount of time during which time it damages cancerous as well as healthy structures. Dr. Gerhard Pütz and Dr. Jürgen Eckes founded the company TellTargeting Medical GmbH Co. KG…https://www.gesundheitsindustrie-bw.de/en/article/news/telltargeting-medical-gmbh-targeted-chemotherapy-using-carl
Article - 03/06/2013 Laser light for the diagnosis of stroke Stroke is one of the most common causes of death in the Western world and in Germany the most common cause of moderate to severe disabilities. Besides effective prevention, the rapid and specific diagnosis of impaired blood circulation in the brain is key in the effective treatment of stroke patients. PD Dr. Thomas Gisler from the University of Konstanz has developed CereFLux, a method that allows the flow of blood in the human brain to be…https://www.gesundheitsindustrie-bw.de/en/article/news/laser-light-for-the-diagnosis-of-stroke
Article - 07/07/2010 Excellent vascular research in Baden-Württemberg The fact that the DFG are continuing to fund the only collaborative research centre (SFB, Sonderforschungsbereich) in Germany that is exclusively focused on vascular research underlines the concentrated expertise found in Mannheim and Heidelberg in the field of vascular biology.https://www.gesundheitsindustrie-bw.de/en/article/news/excellent-vascular-research-in-baden-wuerttemberg
Article - 05/02/2008 Protecting the liver from oxygen stress The Emmy Noether junior research group in the Department of Surgery at the University Hospital of Heidelberg is to be funded with 1.2 million over the next five years. The group will focus on how tissue damage in donor livers can be prevented. The group headed by Dr. Martin Schneider.https://www.gesundheitsindustrie-bw.de/en/article/news/protecting-the-liver-from-oxygen-stress
Article - 19/03/2009 BioTeSys: isolate, characterise, analyse Bioactive substances are the speciality of BioTeSys GmbH an Esslingen-based biotech company. The company works with a range of products including cosmetics plant and berry extracts and low-dosage non-prescription food supplements. BioTeSys investigates the efficacy of the active ingredients of such products as well as the raw materials used to manufacture them. https://www.gesundheitsindustrie-bw.de/en/article/news/biotesys-isolate-characterise-analyse
Press release - 17/10/2008 "Stem cell crazy" For three days from 9 to 11 October more than 300 scientists from over 20 countries met at the Haus der Wirtschaft in Stuttgart to discuss the current state of research the latest product developments and therapies in regenerative medicine and stem cell research.https://www.gesundheitsindustrie-bw.de/en/article/press-release/stem-cell-crazy
Article - 13/11/2017 An artificial heart valve with the potential to grow About 30,000 artificial heart valves are implanted in Germany every year. The durability of these heart valves presents a major challenge, requiring them to be exchanged time and again, especially in young patients. Researchers from the Stuttgart Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have developed a new artificial heart valve material on which cells that are naturally present in a patient’s blood can form new…https://www.gesundheitsindustrie-bw.de/en/article/news/an-artificial-heart-valve-with-the-potential-to-grow