Article - 18/09/2012 Michael Kühl: in search of the gene architects of the heart Michael Kühl is investigating the development of the heart using a broad range of different model organisms. The developmental biologist, director of the Institute of Biochemistry and Molecular Biology at the University of Ulm, also uses evolutionary and systems biology approaches for his work. Kühl’s basic research does not follow an art for art’s sake principle, but also addresses the development of new therapies for the treatment of heart…https://www.gesundheitsindustrie-bw.de/en/article/news/michael-kuehl-in-search-of-the-gene-architects-of-the-heart
Article - 16/05/2011 Oliver Röhrle and the biomechanics of the musculo-skeletal system Dr. Oliver Röhrle contributes to the excellent standards in the field of biomechanics at the University of Stuttgart. He has held one of the popular junior professorships in the Simulation Technology (SimTech) cluster of excellence since 2008 and has recently received a research prize for his work on the biomechanics of the musculo-skeletal system.https://www.gesundheitsindustrie-bw.de/en/article/news/oliver-roehrle-and-the-biomechanics-of-the-musculo-skeletal-system
Article - 10/04/2011 Wilhelm Aicher is committed to regenerative medicine research Laboratory-based regeneration of human cartilage and muscle tissue is his strong suit: Prof. Dr. Wilhelm K. Aicher brings his expertise in cellular and molecular biology to research focusing on the development of innovative therapies for the treatment of tissue damage. Successes such as a knee cartilage made from autologous (patients’ own) cells show that Aicher is on the right track.https://www.gesundheitsindustrie-bw.de/en/article/news/wilhelm-aicher-is-committed-to-regenerative-medicine-research
Press release - 24/09/2009 Researchers successfully colonize a textile implant with human stem cells Researchers at the Hohenstein Institute in Stuttgart, Germany developed a method to embed multipotent mesenchymal stem cells onto the surface fibers of common surgical fabric implants. Using such a product it may be possible to directly motivate the regrowth of critical tissue, such as myocardium after a heart attack. https://www.gesundheitsindustrie-bw.de/en/article/press-release/researchers-successfully-colonize-a-textile-implant-with-human-stem-cells
Article - 03/12/2012 Differences between white, brown and “brite” fat tissue The latest results on the different metabolic pathways used by white and brown fat cells and potential transformations between the two cell types were discussed at the conference “Metabolism 2012: From Signalling to Disease” held on 15th and 16th November 2012 in Heidelberg. A special cell type, so-called “brite” adipocytes, may have the potential to be used in the treatment of obesity and related metabolic diseases such as diabetes.https://www.gesundheitsindustrie-bw.de/en/article/news/differences-between-white-brown-and-brite-fat-tissue
Article - 12/04/2010 The interplay of forces Biomechanics not only deals with forces and movements generated by an organism, but also with the effects of external forces acting on cells and organs: Mechanical forces can be specifically used to boost changes in the body. Scientists in the Continuum Mechanics Department at the University of Stuttgart are investigating the biomechanical basis of such forces and their effects.https://www.gesundheitsindustrie-bw.de/en/article/news/the-interplay-of-forces
Article - 19/03/2012 When the “second brain” fails – therapeutic options from the field of regenerative medicine Researchers from the Center for Regenerative Biology and Medicine ZRM in Tübingen are focused on the enteric nervous system of the gastrointestinal tract with the aim of developing cell-based therapies for the treatment of bowel diseases. The researchers are working with local partners in a BMBF-funded project that is seeking to develop therapies for Hirschsprung’s disease.https://www.gesundheitsindustrie-bw.de/en/article/news/when-the-second-brain-fails-therapeutic-options-from-the-field-of-regenerative-medicine
Article - 29/11/2010 Going through the eye of a needle: Translating research findings into individualised patient treatment Anyone attempting to assess the importance of pharmacogenetics for drug safety will inevitably end up considering the ambiguous responses of Radio Eriwan. It is true that genetic tests are theoretically able to predict whether an inactive enzyme affects the metabolism of a drug and whether it is necessary to apply a different drug dose. But how can this knowledge be applied in everyday clinical settings when patients with this inactive enzyme are…https://www.gesundheitsindustrie-bw.de/en/article/news/going-through-the-eye-of-a-needle-translating-research-findings-into-individualised-patient-treatmen
Article - 23/05/2011 KIT researchers attempt to grow cardiomyocytes in Petri dishes Regenerative medicine specialists are aiming to be able to grow complete organs from stem cells some time in the future. However although the microscopically small cells are able to do many things they are not able to grow organs on their own. Dr. Alexandra Rolletschek and her team at the Karlsruhe Institute of Technology KIT are investigating how stem cells can be grown into heart muscle cells cardiomyocytes in Petri dishes. https://www.gesundheitsindustrie-bw.de/en/article/news/kit-researchers-attempt-to-grow-cardiomyocytes-in-petri-dishes
Article - 07/04/2009 Sick hearts as instructors In a joint project with heart surgeons from Freiburg pharmacologist Professor Dr. Lutz Hein and his team at the University of Freiburg are working to uncover the mystery of spontaneous self-healing in the case of chronic cardiac insufficiency. Initial results suggest the involvement of genetic mechanisms amongst other things.https://www.gesundheitsindustrie-bw.de/en/article/news/sick-hearts-as-instructors
Press release - 21/08/2009 How to organise cooperations effectively In order for a company to make efficient use of its potential and its specific skills it must focus on its own core competences and on the cooperation with other companies that have supplementary skills. This is all the more important in economically difficult times when investors and banks tend to shy away from investments. The implementation of cooperations between companies raises a number of general issues as well as specific issues relating…https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-to-organise-cooperations-effectively
Article - 18/03/2010 Boehringer Ingelheim researchers to focus on inflammation Boehringer Ingelheim is hoping to find ways to use anti-inflammatory mechanisms of action to improve the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. Clinical studies will show what kind of improvements patients can expect from the substances, which are currently at different stages of development. Drugs to widen the bronchia, marketed by Boehringer Ingelheim, will in the medium term become…https://www.gesundheitsindustrie-bw.de/en/article/news/boehringer-ingelheim-researchers-to-focus-on-inflammation
Article - 19/03/2012 Calcium channels – about channel proteins and why we forget things The controlled transport of calcium across cell membranes is crucial for many biological processes including the transfer of information into the brain kidney function and the rhythmic activity of the heart muscle. A team led by Prof. Dr. Norbert Klugbauer at the University of Freiburg is focused on elucidating the function of calcium channels the proteins that regulate them and the effects on learning and memory. The researchers are…https://www.gesundheitsindustrie-bw.de/en/article/news/calcium-channels-about-channel-proteins-and-why-we-forget-things
Article - 25/03/2013 Ralf Baumeister – tinkering, constructing and switching off genes The focus of Ralf Baumeisters research a small nematode that is known as Caenorhabditis elegans is a rather simple organism. Nevertheless the worm can be used to study complicated behaviour including associated learning. This is how Prof. Dr. Ralf Baumeister from the Institute of Biology III at the University of Freiburg describes the animal that he works with on a daily basis. The worm has now got very little left to hide. And the genetic…https://www.gesundheitsindustrie-bw.de/en/article/news/ralf-baumeister-tinkering-constructing-and-switching-off-genes
Press release - 04/07/2018 Phase-I-trial approved for novel stem cell therapy for patients with ischemic cardiomyopathy Viscofan BioEngineering, the biomedical business unit of the world market leader for collagenous sausage casings Viscofan announced today that the Spanish Agency for Medicines (AEMPS) has given green light to carry out a clinical phase-I-trial with Viscofan BioEngineering’s first product for regenerative medicine. The novel therapy consisting of stem cells on a collagenous carrier membrane can now be tested on ten patients suffering from severe…https://www.gesundheitsindustrie-bw.de/en/article/press-release/phase-i-trial-approved-for-novel-stem-cell-therapy-for-patients-with-ischemic-cardiomyopathy
Press release - 08/05/2010 Natural movements with artificial legs Prosthesis users find it very difficult to cope with everyday situations: artificial legs do not always work as they should and movements often tend to be fairly awkward. Researchers from the Fraunhofer Institute for Manufacturing Engineering and Automation IPA in Stuttgart are to present a motion control system that enables prosthesis users to intuitively move the prosthesis in the same way as a natural leg. The new system will be presented at…https://www.gesundheitsindustrie-bw.de/en/article/press-release/natural-movements-with-artificial-legs
Press release - 15/10/2008 Hans-Jürgen Apell - insights into active ion transport Biophysicist Prof. Hans-Jürgen Apell carries out basic research at the University of Constance in order to elucidate the molecular mechanisms involved in the transport of ions through membranes and to come up with important findings for new therapeutic concepts. His major field of research focuses on structure-function relationships of P-type ATPases enzymes which cleave ATP adenosine triphosphate and transport ions thereby resulting in muscle…https://www.gesundheitsindustrie-bw.de/en/article/press-release/hans-juergen-apell-insights-into-active-ion-transport
Press release - 08/09/2010 Gene doping detectable with a simple blood test Scientists at the universities of Tübingen and Mainz have developed a blood test that is able to provide conclusive proof of gene doping. The test is still effective even if the actual doping took place some time before the test. The new test is based on a procedure developed in Tübingen in 2006 that enables transgenic DNA to be detected in the blood. The efficiency of this procedure has now been proven for the first time in laboratory mice. https://www.gesundheitsindustrie-bw.de/en/article/press-release/gene-doping-detectable-with-a-simple-blood-test
Article - 21/05/2012 Microchip facilitates bowel movements Faecal incontinence is a common problem, but is still a strong taboo. A small microchip, implanted above the sacral bone, promises to make sufferers’ lives a lot easier. Sacral nerve stimulation (SNS) not only restores patients’ ability to control defaecation, but also provides new insights into the innervation and physiology of the bowel and the pelvic floor.https://www.gesundheitsindustrie-bw.de/en/article/news/microchip-facilitates-bowel-movements
Article - 17/10/2011 Aristides Arrenberg uses light to investigate the working memory Dr. Aristides Arrenberg from the University of Freiburg did his doctorate in the USA where he further developed a method that can be used to silence or activate specific zebrafish nerve cells at will. The method is based on light stimuli that trigger cellular switches. In addition the researchers have recently published an article on research into how eye movements are stored in the hindbrain. Standard network models used for so-called integrator…https://www.gesundheitsindustrie-bw.de/en/article/news/aristides-arrenberg-uses-light-to-investigate-the-working-memory
Article - 20/05/2008 Hugo Hämmerle: At the crossroads between research and industry The NMI Natural and Medical Sciences Institute in Reutlingen is a role model for how research findings can be turned into financially sustainable products and services. Prof. Hugo Hämmerle has been a key figure in this success story for over 20 years. In February 2008 he took over as Managing Director of the institute. https://www.gesundheitsindustrie-bw.de/en/article/news/hugo-haemmerle-at-the-crossroads-between-research-and-industry
Article - 21/08/2018 Parkinson's disease: vitamin B3 has a positive effect on nerve cells Parkinson's disease is one of the most common neurodegenerative diseases in the world. There are around 4.1 million sufferers worldwide. It is characterised by motor impairments that result from the death of certain nerve cells in the brain. Researchers at the University of Tübingen have now discovered that vitamin B3 has a positive effect on damaged nerve cells and can boost their energy metabolism.https://www.gesundheitsindustrie-bw.de/en/article/news/parkinsons-disease-vitamin-b3-has-a-positive-effect-on-nerve-cells
Article - 12/05/2016 Novel method for predicting the spatial structure of biomolecules Biomolecules can only fulfil their functions in the cell when they fold into a characteristic native three-dimensional structure. Knowing this structure is not only of paramount importance for basic research, but also for medicine and pharmacology. Scientists from the Karlsruhe Institute of Technology (KIT) have therefore developed a simple method to predict the three-dimensional structure of biomolecules from the analysis of readily available…https://www.gesundheitsindustrie-bw.de/en/article/news/novel-method-for-predicting-the-spatial-structure-of-biomolecules
Dossier - 01/02/2010 Metabolic diseases Metabolic diseases are characterised by disorders of the intermediary metabolism which can either be inherited or acquired. The extent and incidence of metabolic diseases can differ considerably and can range from widespread diseases such as diabetes to rare congenital diseases that frequently have a fatal outcome. Through new approaches in genome research amongst other things science and industry are increasingly focusing on metabolic diseases.https://www.gesundheitsindustrie-bw.de/en/article/dossier/metabolic-diseases
Article - 27/08/2012 Cardiac or intestinal progenitor cells? What controls the fate of pluripotent stem cells? Cell fate decisions are made in the early mouse embryo when it is nothing more than a spherical mass of cells. A molecule known as eomesodermin determines whether pluripotent stem cells become cardiac or intestinal progenitor cells. Dr. Sebastian Arnold and his research group at the Freiburg University Medical Centre have recently discovered why one single molecule can have a twofold effect. These findings provide Arnold and his team with greater…https://www.gesundheitsindustrie-bw.de/en/article/news/cardiac-or-intestinal-progenitor-cells-what-controls-the-fate-of-pluripotent-stem-cells