Press release - 20/05/2021 Immune cells promote proinflammatory fatty liver disease A particular type of dendritic cell is responsible for the tissue damage that occurs in non-alcoholic steatohepatits (NASH) in mice and humans. The dendritic cells cause aggressive, proinflammatory behavior in T cells, as now discovered by researchers from the German Cancer Research Center (DKFZ) in collaboration with colleagues from Israeli research institutes. Blocking these dendritic cells alleviates symptoms in mice.https://www.gesundheitsindustrie-bw.de/en/article/press-release/immune-cells-promote-proinflammatory-fatty-liver-disease
Press release - 15/03/2021 How novel pathogens may cause the development of colorectal cancer Do BMMFs, the novel infectious agents found in dairy products and bovine sera, play a role in the development of colorectal cancer? Scientists led by Harald zur Hausen detected the pathogens in colorectal cancer patients in close proximity to tumors. The researchers show that the BMMFs trigger local chronic inflammation, which can cause mutations via activated oxygen molecules and thus promote cancer development in the long term.https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-novel-pathogens-may-cause-development-colorectal-cancer
Dossier - 06/12/2019 Microbiome: human health is closely connected with our microbial communities People have 1.3 times more microorganisms than body cells. This microbial community influences how we digest our food, how active our immune system is, as well as whether we tend to be more anxious or curious. A number of diseases have also been shown to be associated with a disturbed microbiome. Researchers still have a long way to go before the knowledge acquired can be used for developing therapies.https://www.gesundheitsindustrie-bw.de/en/article/dossier/microbiome-human-health-closely-connected-with-microbial-communities
Article - 11/06/2019 New pathogens in beef and cow's milk contributing to the risk of cancer A team of researchers led by Nobel laureate Prof. Dr. med. Dr. h.c. mult. Harald zur Hausen has discovered a new type of infectious agent in dairy and meat products produced from European cattle that increases the risk for colon and breast cancer. These so-called Bovine Meat and Milk Factors (BMMFs) are small DNA molecules that are similar in sequence to both bacterial plasmids and certain viruses.https://www.gesundheitsindustrie-bw.de/en/article/news/new-pathogens-in-beef-and-cows-milk-contributing-to-the-risk-of-cancer
Expert interview on NTDs – part 2 - 29/05/2019 Neglected tropical diseases - Gisela Schneider: the burden of disease "Leaving no one behind". The motto of the 2030 Agenda with its 17 Sustainable Development Goals (SDGs) which was signed by the United Nations (UN) in 2015 makes clear that combatting poverty and its consequences is an essential part of sustainable development. The fight against neglected tropical diseases (NTDs) is defined as a major aim of the Agenda’s sustainable development goals. The World Health Organisation (WHO) regards twenty…https://www.gesundheitsindustrie-bw.de/en/article/news/neglected-tropical-diseases-gisela-schneider-the-burden-of-disease
Article - 24/01/2019 Scientists to combat antibiotic-resistant bacteria in wastewater In Germany, around 1,500 tonnes of antibiotics per year are administered to humans and animals. As a result, more and more bacteria are developing resistance to common antibiotics. As part of HyReKA, a cooperative project funded by the BMBF, scientists led by Professor Thomas Schwartz from the KIT are investigating how antibiotic-resistant pathogens spread and how they can be prevented from doing so.https://www.gesundheitsindustrie-bw.de/en/article/news/scientists-to-combat-antibiotic-resistant-bacteria-in-wastewater
Funding Future Insight Prize Funding programme, Funded by: Merck KGaA, Submission deadline: 31/12/2021 https://www.gesundheitsindustrie-bw.de/en/database/funding/future-insight-prize
Article - 07/06/2017 A gene that regulates body heat and fat storage Researchers from Heidelberg have shown that the organismal balance between heat production and energy storage is regulated by a gene called THADA. In animal experiments, knocking out the THADA gene leads to excessive food intake, obesity and sensitivity to cold. As humans spread throughout the world and settled in different climate zones, THADA was exposed to high selection pressure due to evolutionary adaptation. This explains why human…https://www.gesundheitsindustrie-bw.de/en/article/news/a-gene-that-regulates-body-heat-and-fat-storage
Article - 21/07/2016 New anticancer drugs – hop compounds have the potential to treat cancer Secondary hop compounds appear to have a positive effect on the immune system and therefore have the potential to be used for the treatment and prevention of cancer. However, the bioavailability of hop compounds in the human body is relatively poor. Researchers from Hohenheim and Tübingen are therefore looking for a way to increase their absorption rate.https://www.gesundheitsindustrie-bw.de/en/article/news/new-drugs-for-the-treatment-of-cancer-hop-compounds-have-the-potential-to-treat-cancer
Article - 30/06/2016 Why fasting is good for health A protein in the nucleus of liver cells is produced in greater quantities when we go hungry; it limits fatty acid uptake and adjusts the metabolism in the liver. However in people with metabolic disorders, the abnormal expression of this protein (GADD45β), which was previously only known to be involved in the regulation of cell division and DNA repair, leads to a dysregulated fat and sugar metabolism. Scientists from the DKFZ and Helmholtz…https://www.gesundheitsindustrie-bw.de/en/article/news/why-fasting-is-good-for-health
Article - 01/03/2016 Tübiom – the gut flora’s role in human health and disease It’s the mix that makes it work: a large number of different bacteria live in our intestine and ensure proper digestive functioning. CeMeT GmbH has launched the Tübiom project to explore bacterial gut flora and how it alters with lifestyle, diet and disease. The long-term objective is to derive recommendations for intestinal health. https://www.gesundheitsindustrie-bw.de/en/article/news/tuebiom-the-gut-floras-role-in-human-health-and-disease
Article - 11/01/2016 Study shows correlation between intestinal gene activity and obesity People with obesity suffer from more than just health problems related to their weight. They often feel socially stigmatised because their disease is often seen as a self-inflicted condition. A new study by the University of Hohenheim in cooperation with the eSwiss Medical and Surgical Center in St. Gallen now shows that severe obesity is closely associated with gene activity in the intestinal tissue. This activity is responsible for producing…https://www.gesundheitsindustrie-bw.de/en/article/news/studie-zeigt-zusammenhang-zwischen-gen-aktivitaet-im-darm-und-uebergewicht
Telemedicine - 19/10/2015 Medical apps – potential helpers for physicians and patients Can smartphones become health counsellors for patients or diagnostic tools for doctors? The answer is yes, at least technically. However, health apps that comply with valid medical device regulations are still rather rare in Germany. Many health insurance companies are reluctant to pay for the use of these modern tools because the legal framework is inadequate and doctors are not yet fully capable of using them. Nevertheless, the use of such…https://www.gesundheitsindustrie-bw.de/en/article/news/medical-apps-potential-helpers-for-physicians-and-patients
Overview Basic research The latest articles, press releases and dossiers on basic research in Baden-Württemberghttps://www.gesundheitsindustrie-bw.de/en/article/research
Article - 05/01/2015 Protein foils for sausages and seeds Sausage casings made of collagen can be used as an alternative to natural intestine casings as they give a similar sensation when biting into knockwursts or boiled sausages. Scientists involved in the German Federal Ministry of Education and Research funded project "Biotechnological process development for novel membranes based on collagen", are seeking to optimise the process of collagen processing using environmentally friendly…https://www.gesundheitsindustrie-bw.de/en/article/news/protein-foils-for-sausages-and-seeds
Article - 15/12/2014 Heart muscle cell 1.0 and 2.0 – two epigenetic programmes in one cell All the cells in an organism have to adapt to changing requirements as they develop and grow - including muscle cells in the heart. Crucial to this process are the cells’ growth in size and epigenetic factors that play a role in modulating the expression of various genes. The role of epigenetics in cancer development has been the focus of research for quite some time. The question is, what role do epigenetic factors play in the development of the…https://www.gesundheitsindustrie-bw.de/en/article/news/heart-muscle-cell-1-0-and-2-0-two-epigenetic-programmes-in-one-cell
Article - 30/06/2014 The German National Cohort: collecting data for a healthier future A large-scale long-term cohort study will be carried out to explain the causes of widespread diseases, in particular cancer, coronary heart disease, stroke and diabetes, and to identify the risk factors that lead to or favour the development of a certain disease. The principal objective of the German National Cohort (GNC) is to create the conditions that enable the development of new strategies for the prevention, risk assessment and early…https://www.gesundheitsindustrie-bw.de/en/article/news/the-german-national-cohort-collecting-data-for-a-healthier-future
Article - 02/06/2014 Researchers shed light on important metabolic pathway A research team led by microbiologist Dr. David Schleheck, in cooperation with chemists from the University of Konstanz, has discovered how sulpho-glucose is degraded in Escherichia coli bacteria. As this sulphurous glucose analogue is produced by all photosynthetically active organisms, the researchers’ discovery is of great importance for our understanding of the global sulphur cycle. https://www.gesundheitsindustrie-bw.de/en/article/news/researchers-shed-light-on-important-metabolic-pathway
Article - 25/11/2013 GlucoChat: a communication platform for the treatment of young patients with type I diabetes The idea of being able to access a secure and relatively straightforward way of communicating with others as part of a social network definitely appeals to those who live several hundred kilometres away from a specialist doctor. However, data protection issues present a number of difficulties. careon, an e-health company from Tübingen, has found a solution by developing a platform for social network applications in which data remains…https://www.gesundheitsindustrie-bw.de/en/article/news/glucochat-a-communication-platform-for-the-treatment-of-young-patients-with-type-i-diabetes
Dossier - 18/11/2013 Innovative textiles made possible by biotechnology Biotechnology plays a part in many high-tech fabrics that have become an integral part of our everyday life. Whether it is products for the treatment of wounds, fabrics for marquees or for clothing, many materials have been developed or are produced using biotechnological techniques and processes. Many products marketed as “micro” or “nano” are inspired by nature. The current topic of the month addresses different aspects of innovative textiles…https://www.gesundheitsindustrie-bw.de/en/article/dossier/innovative-textiles-made-possible-by-biotechnology
Article - 16/09/2013 Jörg Hinrichs and the world of dairy products What is the best way to bring together biology, chemistry, physics and the engineering sciences? Prof. Dr.-Ing. Jörg Hinrichs, director of the Department of Animal Foodstuff Technology and head of the Dairy for Research and Training at the Institute for Food Technology at the University of Hohenheim knows how: become a food technologist!https://www.gesundheitsindustrie-bw.de/en/article/news/joerg-hinrichs-and-the-world-of-dairy-products
Article - 16/09/2013 Infrared light as an indicator of wine quality Guaranteeing the quality of wines is becoming increasingly important so that they are able to compete in the international market. However, the quality control methods currently used are often rather time-consuming and costly. In addition, it is difficult to detect microbial grape contaminations that might jeopardise the quality of the wines. Researchers at the National Training and Research Institute for Viticulture and Horticulture in…https://www.gesundheitsindustrie-bw.de/en/article/news/infrared-light-as-an-indicator-of-wine-quality
Article - 07/08/2013 New regulations covering the use of laboratory animals The new directive of the European Parliament and of the Council on the protection of animals used for scientific purposes was adopted on 22nd September 2010 and was implemented into the German Animal Welfare Act which came into force in February 2013. These regulations have implications for companies and researchers alike. In recent years a growing number of alternative methods to animal testing have been developed. Dr. Nina Hasiwa CEO of…https://www.gesundheitsindustrie-bw.de/en/article/news/new-regulations-covering-the-use-of-laboratory-animals
Article - 29/07/2013 Food supplements from blue-green algae do more harm than good Dietary supplements containing different types of algae claim to be rich in minerals that help improve mental acuity and concentration. While many of these products are neither useful nor harmful, products containing blue-green algae have raised serious concerns. Consumers have repeatedly complained about pain and discomfort after consumption. A study carried out by toxicologist Prof. Dr. Daniel Dietrich from the University of Konstanz has now…https://www.gesundheitsindustrie-bw.de/en/article/news/food-supplements-from-blue-green-algae-do-more-harm-than-good
Article - 15/07/2013 A horse in cow’s clothing Control is good dual control even better. Blind trust in the food industry is not always the best idea. Dioxin EHEC and the horsemeat scandal show how vulnerable safety of the food chain is in a globalised world and also highlights the continuously changing challenges facing food inspectors. Food inspection aims to protect consumers from potential harm caused by food and against fraud committed by the industry.https://www.gesundheitsindustrie-bw.de/en/article/news/a-horse-in-cow-s-clothing