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  • Article - 25/01/2014 20891_de.jpg

    Call for responsible antibiotics prescription

    Heidelberg University Hospital and the University Medical Centre in Mannheim are working hard to counteract the increase of antibiotic resistance. Strategies include a European-wide system for infection surveillance, the training of health professionals in the responsible use of antibiotics and the search for novel antibiotic substances in unconventional organisms.

    https://www.gesundheitsindustrie-bw.de/en/article/news/call-for-responsible-antibiotics-prescription
  • Article - 20/01/2014 The photo shows a small metal device with wires and standing in a mount.

    Microarray copier – for copying DNA, RNA and protein arrays

    Dr. Günter Roth from the Centre for Biological Systems Analysis at the University of Freiburg is working on the development of a microarray copier that can almost at the push of a button copy arrays of any type of molecule DNA RNA and proteins from next-generation sequencing chips onto standard slides thereby combining the world of microarrays with the sequencing world. The approach has a huge application potential for the production of…

    https://www.gesundheitsindustrie-bw.de/en/article/news/microarray-copier-for-copying-dna-rna-and-protein-arrays
  • Article - 20/01/2014 20602_de.jpg

    Curetis AG: Miniaturised laboratory for the simple, rapid and reliable diagnosis of serious infections

    Acute pneumonia usually leaves doctors with no choice the situation can quickly become life threatening requiring doctors to act quickly. Instead of waiting for laboratory results they often prescribe an antibiotic that is effective against numerous bacterial species in the hope that it will also work against the bacterium that has caused the inflammation in the lung tissue. Curetis AG from Holzgerlingen close to Stuttgart has developed a…

    https://www.gesundheitsindustrie-bw.de/en/article/news/curetis-ag-miniaturised-laboratory-for-the-simple-rapid-and-reliable-diagnosis-of-serious-infections
  • Article - 29/11/2013 20630_de.jpg

    QIAGEN Lake Constance: a “disk player” for rapid diagnoses

    The diagnosis of infectious diseases frequently not only depends on the reliable identification of the pathogenic species that has caused them, but also on obtaining rapid results in order to immediately initiate appropriate therapy or further diagnostic measures. Tests are normally carried out in central laboratories, samples need to be sent to the laboratories and the results are rarely immediate. As part of the BMBF-funded project “ResCheck”,…

    https://www.gesundheitsindustrie-bw.de/en/article/news/qiagen-lake-constance-a-disk-player-for-rapid-diagnoses
  • Article - 31/10/2013 Fruit mummy, a small, unripe, dried-up fruit of the previous year, on an apple tree.

    Fire blight monitoring generates new knowledge

    Plant diseases such as fire blight, a common infectious disease that predominantly affects pomaceous fruit trees, can reach epidemic proportions. Weather-based prediction models, which are routinely used to calculate fire blight infection risk, can now be replaced by a molecular test that is far more accurate. This new test is used by Bio-Protect GmbH and Büro für Biologische-Ökologische Beratung, both located in Konstanz and members of BioLAGO,…

    https://www.gesundheitsindustrie-bw.de/en/article/news/fire-blight-monitoring-generates-new-knowledge
  • Article - 14/10/2013 This curve shows the comparison of CopraRNA with other methods

    Online-tool predicts functions of regulatory RNAs

    Metabolism stress response and gene expression are all controlled by regulatory networks in living systems. Well-known regulators are proteins which function as enzymes chaperones or transcription factors to regulate numerous processes. Less well-known are RNA-molecules which also regulate a multitude of processes small RNAs or sRNAs. Dr. Jens Georg from the Department of Genetics and Experimental Bioinformatics at the University of Freiburg has…

    https://www.gesundheitsindustrie-bw.de/en/article/news/online-tool-predicts-functions-of-regulatory-rnas
  • Dossier - 09/09/2013 Immunofluorescence image of two dendritic mouse cells with MHC complexes (labelled with red-fluorescent antibodies) on their surface.

    New trends in the field of immunology

    B- and T- lymphocytes along with macrophages have long been regarded as the most important cells of the human immune system and have thus been a major focus of research. This has now changed and it is now the dendritic cells that are regarded as the major components of the adaptive immune system and have become a major focus of scientific interest. Research into innate immune defence mechanisms has also become more important due to the discovery…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/new-trends-in-the-field-of-immunology
  • Press release - 05/08/2013 Logo greenovation

    greenovation Biotech GmbH – production of therapeutic proteins in moss

    Plants can be genetically modified in a way that enables them to produce pharmaceutically active proteins for various indications. The small moss Physcomitrella patens is able to produce more complex molecules than bacteria. Moreover, moss is less expensive to grow and less susceptible to pathogenic contaminants than Chinese hamster ovary (CHO) cells. greenovation Biotech GmbH, which has its headquarters in Heilbronn and a branch in Freiburg,…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/greenovation-biotech-gmbh-production-of-therapeutic-proteins-in-moss
  • Article - 17/06/2013 19848_de.jpg

    EHEC prevention: mission ‘safe salad’

    Raw fruit and vegetables are popular and healthy, at least as long as they are not contaminated with pathogens such as those that caused the EHEC outbreak in 2011 where sprouted foods were identified as the source of the E. coli outbreak. Researchers from the University of Hohenheim are looking into how the risk of consumers being infected by ready-to-eat vegetables and salads can be minimised.

    https://www.gesundheitsindustrie-bw.de/en/article/news/ehec-prevention-mission-safe-salad
  • Article - 03/06/2013

    With metabolomics food analytics goes all the way

    In the not-too-distant future, food analysts hope they will be able do more than just detect mycotoxin traces and determine the concentration of individual nutrients such as vitamin C. Their ambition is in fact much broader: “We would like to understand the nutritional and physiological effect of food,” said Prof. Sabine Kulling from the Max Rubner Institute in Karlsruhe. As with other life sciences areas, metabolomics is seen as a key technology…

    https://www.gesundheitsindustrie-bw.de/en/article/news/with-metabolomics-food-analytics-goes-all-the-way
  • Press release - 02/05/2013 15740_de.jpg

    Curetis raises EUR 12.5 million in Series B round led by new investor HBM Partners

    On the 22nd April 2013 the Curetis AG in Holzgerlingen announced the closing of a Series B financing round totaling EUR 12.5 million. The financing was led by HBM Partners. Dr. Alexander Asam of HBM will join Curetis’ supervisory board. Curetis will use the proceeds for the next phase of commercial and operational growth.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/curetis-raises-eur-12-5-million-in-series-b-round-led-by-new-investor-hbm-partners
  • Dossier - 01/04/2013 19423_de.jpg

    Retroviruses: from infectious agent to therapeutic assistant

    Viruses are infectious particles that use the machinery and metabolism of a host cell to replicate. Despite some similarities with accepted forms of life viruses are not considered as such. The family of retroviruses is particularly known for its most notorious representative i. e. the human immunodeficiency virus HIV which leads to AIDS and for which no cure or effective vaccine is currently available. However retroviruses are not only of…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/retroviruses-from-infectious-agent-to-therapeutic-assistant
  • Article - 18/02/2013 18791_de.jpg

    AIDS researchers from Ulm to shed light on the success of the HIV-1 M group

    Frank Kirchhoff AIDS researcher at the University of Ulm has come up with a plausible explanation for the pandemic spread of the human immunodeficiency virus 1 HIV-1 M group and its ability to adapt to the human immune system. In a recent study with colleagues from Germany and abroad Kirchhoff used molecular biology methods to investigate the group and compare it with the relatively rare HIV-1 N group. Kirchhoff hopes that the molecular…

    https://www.gesundheitsindustrie-bw.de/en/article/news/aids-researchers-from-ulm-to-shed-light-on-the-success-of-the-hiv-1-m-group
  • Article - 11/02/2013 Schematic with two artificial liposomes. The membrane on the left contains phospholipids and the receptors are positioned far away from each other. The membrane of the liposome on the right also contains cholesterol and sphingomyelin, which makes the receptors aggregate into clusters.<br />

    Cholesterol boosts the memory of the immune system

    Cholesterol has been demonised for a long time as high cholesterol levels are seen as major risk factors for atherosclerosis myocardial infarction and gallstones. However cholesterol is an essential component of mammalian cell membranes and is required for proper membrane function. It exists in huge quantities in the human body. In addition to being essential for cell survival and hence all animal life in general cholesterol also plays a crucial…

    https://www.gesundheitsindustrie-bw.de/en/article/news/cholesterol-boosts-the-memory-of-the-immune-system
  • Article - 11/02/2013 19149_de.jpg

    Johannes Krause examines historical pathogens: old pathogens in a new light

    Palaeogeneticist Johannes Krause is drawn to ancient DNA. His work on the evolution of human pathogens shows that his findings are not purely of historical interest, but also enable conclusions to be made on future disease outbreaks and epidemics. In autumn 2012, Krause was awarded an ERC Starting Grant. Krause uses the grant to expand his research into plague and other historical pathogens that continue to be a threat to human health.

    https://www.gesundheitsindustrie-bw.de/en/article/news/johannes-krause-examines-historical-pathogens-old-pathogens-in-a-new-light
  • Article - 31/12/2012 18916_de.jpg

    Diagnosis of myocardial infarction: a drop of blood is all that is required

    Can myocardial infarction be diagnosed with a single drop of blood? The answer is yes: a new application of the ESEQuant Lateral Flow System developed by QIAGEN now makes this possible. The system, which is able to identify a broad range of bacterial and viral pathogens, including HIV, influenza virus and Chlamydia, was originally developed at the company’s site in Stockach. It has recently been adapted for use in the diagnosis of myocardial…

    https://www.gesundheitsindustrie-bw.de/en/article/news/diagnosis-of-myocardial-infarction-a-drop-of-blood-is-all-that-is-required
  • Press release - 17/12/2012 15740_de.jpg

    Curetis AG initiates clinical trial in the U.S. towards FDA clearance

    Curetis AG announced the start of a clinical trial of its Unyvero™ System and the corresponding LRT (lower respiratory tract) application in the U.S. The company expects enrollment completion within the next 12-15 months, followed by a 510(k) submission to the FDA in 2014. The prospective, multicenter trial will include samples collected from more than 2,000 hospitalized patients suspected to have a lower respiratory tract infection and several…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/curetis-ag-initiates-clinical-trial-in-the-u-s-towards-fda-clearance
  • Press release - 22/11/2012 18767_de.jpg

    CeGaT and Genomatix are finalists of Boston Children’s Hospital’s CLARITY challenge

    CeGaT (Center for Genomics and Transcriptomics) GmbH, the Department of Prostate Cancer Research, Institute of Pathology, University Hospital Bonn and Genomatix Software GmbH were announced as finalist (Top 3) of the CLARITY challenge, organized by Boston Children’s Hospital.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/cegat-and-genomatix-are-finalists-of-boston-children-s-hospital-s-clarity-challenge
  • Press release - 15/11/2012 18690_de.jpg

    How bacteria attack their host cells with sticky lollipops

    Yersinia enterocolitica, a pathogenic bacterium, causes fever and diarrhea. By help of a protein anchored in its membrane, Yersinia attaches to its host cells and infects them. Scientists of the Max Planck Institute for Developmental Biology in Tübingen and the Leibniz-Institut fuer Molekulare Pharmakologie in Berlin have determined the structure of an important component of the membrane protein and have gained insight into its biogenesis. The…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-bacteria-attack-their-host-cells-with-sticky-lollipops
  • Article - 12/11/2012 18619_de.jpg

    Autoimmune diseases – when the body sheds its skin

    Most people believe that snakes and insects are the only animals able to shed their skin. However autoimmune diseases of the largest human organ i.e. the skin can have a similar effect by creating blisters scars peeling and wet wounds. Dr. Cassian Sitaru from the University of Freiburg Medical Centre specifically focuses on blistering autoimmune dermatoses. Using disease models in Petri dishes and laboratory mice Sitaru and his team hope to find…

    https://www.gesundheitsindustrie-bw.de/en/article/news/autoimmune-diseases-when-the-body-sheds-its-skin
  • Article - 15/10/2012 18369_de.jpg

    gerbion®: hunting down pathogens

    Detecting viruses, bacteria or parasites in human, animal, food and environmental samples is routine for the staff of gerbion GmbH & Co. KG. The company has been using virological, microbiological and serological methods for many years, but is now also using cutting-edge molecular biology methods for detecting pathogens. The founders of the Kornwestheim-based diagnostics company have concentrated on own research work and the development of…

    https://www.gesundheitsindustrie-bw.de/en/article/news/gerbion-hunting-down-pathogens
  • Press release - 16/08/2012 17909_de.jpg

    Blood cancer cells initiate signalling cascade

    Researchers of the University of Freiburg have identified a new mechanism that causes immune cells to convert into malignant cancer cells. In Chronic Lymphocytic Leukaemia CLL one of the most common types of blood cancer in the Western world cells themselves carry the key for the pathogenic transformation the scientists report in the journal Nature. Understanding these underlying mechanisms could facilitate new therapies with reduced side…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/blood-cancer-cells-initiate-signalling-cascade
  • Article - 30/07/2012 Enterococcus faecalis, a bacterium that frequently occurs in hospitals, seen under the electron microscope.

    How to prevent pathogens from developing antibiotic resistances

    For bacteria, the environment is rather like a big market where they can give and receive new survival strategies if need be. A group of researchers led by Prof. Dr. Elisabeth Grohmann at the Freiburg University Medical Centre is investigating how microorganisms exchange antibiotic resistance genes. In a project involving two hospitals in Mexico City, the molecular biologists are also investigating whether pathogens, resistance genes and…

    https://www.gesundheitsindustrie-bw.de/en/article/news/how-to-prevent-pathogens-from-developing-antibiotic-resistances
  • Article - 30/07/2012 Botrytis cinerea infections proceed in several steps: shortly after infection, the fruit turn a light brownish colour (left); fruit in the final stage of infection are covered completely with conidia (centre). The photo on the right shows healthy, uninfected fruit.

    Fungus protects strawberries against grey rot and does away with the need for chemicals

    Summer time is strawberry time: strawberries are grown worldwide on an area of 300,000 hectares and are harvested in early summer. Fungicides that are used to treat grey rot might actually be the only thing that diminishes the pure pleasure of eating juicy, tasty strawberries. The Konstanz-based company bio-ferm Research GmbH has developed a fungicide that protects strawberries against Botrytis cinerea infections, one of the most common fruit…

    https://www.gesundheitsindustrie-bw.de/en/article/news/fungus-protects-strawberries-against-grey-rot-and-does-away-with-the-need-for-chemicals
  • Press release - 17/07/2012 AnDiaTec Logo

    Schmallenberg virus: Identifying infected cows and sheep faster

    The world's first commercial detection method for the Schmallenberg virus is now available for all laboratories. Kornwestheim-based AnDiaTec GmbH & Co. KG, specialists in detection methods for pathogens in the veterinary field, has just received approval for its product from the Friedrich-Löffler-Institut under the German Ordinance on Working with Animal Pathogens (Tierseuchengesetz). The virus, which has led, among other things, to…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/schmallenberg-virus-identifying-infected-cows-and-sheep-faster

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