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  • Press release - 07/10/2008

    GENEDATA SCREENER® – specialised data analysis for the identification of high-potential lead structures

    Genedata AG has developed a modular software system known as Genedata Screener that is tailored to screening and hit-to-lead applications. Dr. Timo Wittenberg who works at the companys site in Constance Germany told us about the advantages of the software for identifying high-potential leads.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/genedata-screener-specialised-data-analysis-for-the-identification-of-high-potential-lead-structures
  • Dossier - 29/09/2008 This computer-based picture shows a small blue and red coloured molecule that fits into a gap of a large grey molecule. Such molecular interactions are essential for pharmacological research.

    Drug screening - higher throughput, quicker and more effective thanks to automation

    Over the last few years automation has revolutionised the search for pharmaceutical compounds. Using methods such as high-throughput screening or high-content screening it is possible to analyse thousands of molecule activities very quickly.

    https:////www.gesundheitsindustrie-bw.de/en/article/dossier/drug-screening-higher-throughput-quicker-and-more-effective-thanks-to-automation
  • Article - 26/09/2008

    GENOVAC starts a project to develop blocking antibodies for the therapy of hepatitis C infections

    GENOVAC GmbH has started a research project funded by the German Ministry for Business and Technology BMWi as part of the program PRO INNO II for the Development and validation of antibodies as a novel therapeutic concept to block liver infection by hepatitis C Virus.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/genovac-starts-a-project-to-develop-blocking-antibodies-for-the-therapy-of-hepatitis-c-infections
  • Press release - 02/09/2008 Portrait of Professor Elke Guenther

    Elke Guenther: inspired by basic research and application-oriented

    The biologist Prof. Dr. Elke Guenther is head of the Department of Electrophysiology at the NMI where her work involves safety pharmacology the development of biosensors and the characterisation of ion channels in the cell membranes in a broad range of different organ systems.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/elke-guenther-inspired-by-basic-research-and-application-oriented
  • Press release - 28/08/2008

    Günther Schütz and the regulation of gene expression by nuclear receptors

    Professor Dr. Günther Schützs work on the cell- and development-specific gene regulation using nuclear receptors has led amongst other things to new insights into the steroid hormone-dependent early development and differentiation of the nervous system the molecular mechanisms of learning and the development and regulation of drug addiction. Schütz has now been appointed Helmholtz professor which will enable him to continue his work beyond…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/guenther-schuetz-and-the-regulation-of-gene-expression-by-nuclear-receptors
  • Article - 29/07/2008

    Frank Kirchhoff advances AIDS research by posing the right questions

    Frank Kirchhoff an AIDS researcher from Ulm has learnt to pose important questions and find the right answers during his post-graduate studies. This recipe has brought him and his research group international recognition and makes him one of the best AIDS researchers worldwide. Important publications within a very short time and numerous awards are clear evidence of his outstanding achievements. In addition he has just started a clinical trial…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/frank-kirchhoff-advances-aids-research-by-posing-the-right-questions
  • Press release - 28/07/2008 import_04027_de.jpg

    The processing of olfactory cues in animals

    Olfactory researchers have received the go-ahead for a DFG priority programme coordinated by the University of Constance. Funding will be provided for research projects dealing with animals sense of smell and what happens in the brain during this process.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/the-processing-of-olfactory-cues-in-animals
  • Article - 28/07/2008

    25 amino acids against avian influenza

    About a year ago Prof. Dr. Martin Schwemmle and his team at the University Hospital of Freiburg discovered a new starting point in the fight against the H5N1-virus. In the meantime the scientists are working together with the company Pike Pharma to develop a compound.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/25-amino-acids-against-avian-influenza
  • Press release - 27/07/2008 Picture showing leukocytes (dark spots) that have left a small vein.

    White blood cells with 'icing' work far better

    Scientists from Heidelberg Munich and Aachen have shown that the adhesion molecules required by leukocytes to adhere to vascular walls depend on sugar chains for effective immune defence reactions to occur. The results could open up new strategies for the treatment of inflammatory processes.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/white-blood-cells-with-icing-work-far-better
  • Article - 07/07/2008 Arabidopsis seedlings with different sizes

    Control centre for light and cold

    Plants grow well under optimal light conditions but only if they are not under stress. Cell biologists have long assumed that information is exchanged between the molecular signalling pathways that mediate light perception and stress tolerance.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/control-centre-for-light-and-cold
  • Press release - 04/07/2008

    Bracco Imaging: specialist in diagnostic imaging

    In future small bubbles will allow the identification of pathological alterations at a very early stage. Molecular imaging methods developed by Bracco Imaging S.p.A. use a new ultrasound contrast agent. The German subsidiary of the company Bracco Imaging Deutschland GmbH based in Constance develops and sells contrast agents.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/bracco-imaging-specialist-in-diagnostic-imaging
  • Article - 02/07/2008

    The cancer cells' sweet tooth might be their death sentence

    Cancer cells are dangerous foodies. They metabolise far greater amounts of sugar than healthy cells. Nuclear medicine experts make use of cancer cells craving for sugar since the advent of modern positron emission tomography PET. This has led to an improvement in the quality of cancer treatment.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/the-cancer-cells-sweet-tooth-might-be-their-death-sentence
  • Article - 30/06/2008

    Safety is paramount

    The new drug screening and safety pharmacology laboratory at NMI Technologie Transfer GmbH NMI TT GmbH in Reutlingen with its standardised and special test systems complies fully with the requirements of safety pharmacology tests.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/safety-is-paramount
  • Article - 14/06/2008

    Cancer researchers kind Key molecule for tumor cachexia

    Many cancer patients lose a lot of weight Free fatty acids accumulate in the liver and this eventually leads to fatty liver in affected patients. What is called tumor cachexia appears to be caused by signals emitted by the tumor itself.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/cancer-researchers-kind-key-molecule-for-tumor-cachexia
  • Article - 10/06/2008

    Heiko Möller - Uncovering molecular structures

    Professor Heiko Möller teaches chemistry at the University of Constance and is a specialist in nuclear magnetic resonance spectroscopy. He enjoys working with other people including colleagues from the field of chemistry and also biologists and tropical disease specialists. Möller returned from the USA to accept a junior professor position at Constance University.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/heiko-moeller-uncovering-molecular-structures
  • Press release - 19/05/2008 import_04227_de.jpg

    Viruses caught red-handed

    Prof. Thilo Stehle biochemist at the University of Tübingen wants to capture and accurately study the moment at which a virus binds to a cell. He is hoping that further insights into this process might some time enable the development of drugs.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/viruses-caught-red-handed
  • Article - 13/05/2008

    Just follow your nose

    Sharks can sense a few drops of blood in water. In fact they are able to smell blood in dilutions of as little as one to 10 billion. Is it just sharks or piranhas that have such an acute sense of smell? The answer is no - all fish have a highly developed sense of smell.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/just-follow-your-nose
  • Article - 28/04/2008

    Mast cells of the immune system

    Immune cells sometimes kick over the traces. This could lead to allergic reactions. At the Freiburg Max Planck Institute of Immunobiology a group of researchers led by Professor Michael Huber is investigating the mechanisms that can prevent this from happening.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/mast-cells-of-the-immune-system
  • Article - 13/04/2008

    Scientists discover a genetic dependence to nicotine

    Scientists have shown that a particular variant of a receptor gene impacts smoking behaviour and hence confers a 30 increase in risk of lung cancer and a 20 increase in risk of peripheral artery disease PAD.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/scientists-discover-a-genetic-dependence-to-nicotine
  • Article - 16/03/2008 Logo apogenix

    New indication for lead compound of Apogenix

    Isolated tumour cells use to invade healthy brain tissue during the development and growth of glioblastoma multiforme GBM. This mechanism involves the CD95CD95L death system. These results supports the therapeutic potential of Apogenix APG101 for the treatment of glioblastomas.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/new-indication-for-lead-compound-of-apogenix
  • Article - 01/03/2008

    Holger Barth is turning toxins into protein shuttles

    Holger Barth works with a special kind of Trojan horses. The toxicologist from Ulm is investigating bacterial toxins. These proteins manage in a similar way to the ancient Greeks before them to open the barricaded portal of the cells with a trick whereupon they start wreaking destruction.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/holger-barth-is-turning-toxins-into-protein-shuttles
  • Article - 21/02/2008 Dr. Gerrit Begemann is is standing in front of an aquarium.

    The females choose their mates

    The team of researchers led by evolutionary biologist Dr. Gerrit Begemann at Constance University is using swordtails to investigate the development of traits that evolved by sexual selection. Their major focus is the molecular mechanism of growth control in the caudal fin. Or put more simply why do these fish have swords?

    https:////www.gesundheitsindustrie-bw.de/en/article/news/the-females-choose-their-mates
  • Article - 25/01/2008

    Glycosylation pattern as potential target for intervention

    Tumours develop sophisticated strategies to escape the immune defence. One of these strategies is the modification of the cells sugar coat. Specific immune cell receptors bind to these sugars thereby preventing the tumour cell from being discovered by the immune system. Medics from the University of Tübingen are investigating the mechanisms involved and are looking for therapeutic targets.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/glycosylation-pattern-as-potential-target-for-intervention
  • Press release - 14/01/2008

    Prostate cancer: Improving the success of treatment

    Prostate cancer is the most frequent malignant tumour in men. Researchers from Freiburg and Bonn have succeeded in developing the basics for new therapies in particular for the treatment of advanced prostate cancer.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/prostate-cancer-improving-the-success-of-treatment

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