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  • Press release - 01/02/2012 Logo DKFZ, blue letters "DKFZ"

    Defects in the packaging of genetic material in malignant brain tumors

    Glioblastomas are regarded as particularly aggressive brain tumors. In children with glioblastoma, Heidelberg scientists have now discovered genetic alterations that affect the function of DNA packaging proteins known as histones. In a cell, histones serve as coils around which the DNA wraps. At the same time, histones regulate gene activity. Mutations in histone genes have never before been tied to a disease. The group comprising scientists of…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/defects-in-the-packaging-of-genetic-material-in-malignant-brain-tumors
  • Press release - 31/01/2012 10938_de.jpg

    HITS Scientist Rebecca Wade receives professorship at the University of Heidelberg

    Today, Dr. Rebecca Wade, head of the “Molecular and Cellular Modelling” research group at the Heidelberg Institute for Theoretical Studies (HITS), has been appointed to the W3 professorship “Computational Structural Biology” (Faculty of Biosciences/HITS) at the University of Heidelberg.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/hits-scientist-rebecca-wade-receives-professorship-at-the-university-of-heidelberg
  • Article - 30/01/2012 16256_de.jpg

    Silicone application in medical technology

    Silicone is flexible, biocompatible and heat-resistant, characteristics that make organosilicone compounds ideal for a wide range of applications in medical technology. Up until now, the broad application of such compounds has been hampered chiefly by the high surface friction of silicone. The Reutlingen-based company Silcos GmbH has developed special methods for the treatment of surfaces that considerably improve the compound's range of…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/silicone-application-in-medical-technology
  • Article - 23/01/2012 16240_de.jpg

    Peter Rodemann – a career in radiobiology

    Prof. Dr. H. Peter Rodemann has been head of the Division of Radiobiology and Molecular Environmental Research at Tübingen University Hospital for around 20 years. He has been awarded numerous prizes for his outstanding achievements, particularly during the second half of 2011 when he was awarded the Ulrich Hagen Prize by the German Society for Biological Radiation Research as well as being elected member of the German Academy of Sciences…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/peter-rodemann-a-career-in-radiobiology
  • Article - 23/01/2012 16231_de.jpg

    Karen Lienkamp: intelligent surface materials fight off microbes

    Resistant germs are tough and will settle anywhere. They grow on all types of surface which is a major cause for concern for medical doctors and industrial researchers alike. The chemist Dr. Karen Lienkamp Junior Fellow at the Freiburg Institute for Advanced Studies FRIAS and head of a group of junior researchers at the University of Freiburg develops surface materials for biomedical applications and industrial production facilities.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/karen-lienkamp-intelligent-surface-materials-fight-off-microbes
  • Article - 16/01/2012 Dr. Alexander Titz, chemist at the University of Konstanz

    Alexander Titz: molecular design to combat antibiotic-resistant bacteria

    Pseudomonas aeruginosa has become an important cause of infection, and is often picked up in hospitals, especially by patients with weakened immune systems. It can cause respiratory and urinary tract infections, as well as lead to infections on implants and wounds. P. aeruginosa lives in a gel-like matrix, a so-called biofilm that is highly resistant to antibiotics, making it very difficult to eradicate. Dr. Alexander Titz and his team at the…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/alexander-titz-molecular-design-to-combat-antibiotic-resistant-bacteria
  • Article - 19/12/2011 16036_de.jpg

    New research training group to investigate bacterial survival strategies

    The University of Tübingen is to establish a new DFG-funded research training group in which doctoral students from twelve research groups will investigate bacterial survival strategies. The results will contribute to the development of new antimicrobial drugs and also be put to good use in the fields of epidemiology and ecology.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/new-research-training-group-to-investigate-bacterial-survival-strategies
  • Press release - 28/11/2011

    CeCo Labs develops new method for isolating bacterial cell walls

    CeCo Labs UG, founded as a spin-off from the University of Tübingen, has developed an internationally unique method for isolating bacterial cell walls. These are used in research to investigate antibiotic resistance, for example. Unlike conventional techniques, the method developed by CeCo Labs is able to supply a very high number of ultra-pure cell walls extremely quickly. Orders have already been placed by customers across the globe.

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/ceco-labs-develops-new-method-for-isolating-bacterial-cell-walls
  • Article - 21/11/2011 Schematic of a bacterial cell wall to which a layer of tale-shaped molecules is attached.

    Johannes Huebner's interest in intestinal bacteria and their sweet-sour capsule

    Some Enterococcus species are common commensal organisms in human intestines and other species are used in raw-milk cheese where they enhance flavour development. On the negative side enterococci are also a common cause of hospital-acquired infections. Prof. Dr. Johannes Huebner from the Freiburg University Medical Centre is hoping that the bacterias capsular polysaccharides might at some point in the future be used as a vaccine opening the door…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/johannes-huebner-s-interest-in-intestinal-bacteria-and-their-sweet-sour-capsule
  • Article - 14/11/2011 15790_de.jpg

    Marina Freudenberg and Chris Galanos – more than 40 years of bacterial defence research

    This years Nobel Prize in Medicine or Physiology was awarded to three renowned scientists one of whom is the American Bruce Beutler who was instrumental in clarifying the structure of the mammalian Toll-like 4 TLR4 receptor. Prof. Dr. med. Marina Freudenberg and Dr. Dr. h.c. Chris Galanos from the Freiburg-based Max Planck Institute MPI of Immunobiology and Epigenetics have co-authored the key publication that led to the award of the Nobel Prize…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/marina-freudenberg-and-chris-galanos-more-than-40-years-of-bacterial-defence-research
  • Press release - 24/10/2011 15650_de.jpg

    Curetis AG Opens Unyvero™ Cartridge Production Facility

    Curetis AG, an innovative molecular diagnostics company focusing on the development and commercialization of in-vitro diagnostic products for infectious diseases, announced the opening of its state-of-the-art production facility for disposable Unyvero™ cartridges in Bodelshausen (near Tuebingen, Germany).

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/curetis-ag-opens-unyvero-cartridge-production-facility
  • Article - 19/09/2011 15348_de.jpg

    k-labor GmbH – a specialist in material analysis and characterisation

    k-labor GmbH focuses on the initial inspection of samples for the automotive industry and the testing of a broad range of different materials. k-labor also specialises in environmental simulations and durability testing and offers consulting and the transfer of technologies in the plastics sector.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/k-labor-gmbh-a-specialist-in-material-analysis-and-characterisation
  • Article - 29/08/2011 Research group led by Dr. Ute Schepers (left) at KIT.

    Ute Schepers – the therapeutic potential of small RNAs and molecular transporters

    Small RNAs can specifically interfere with cellular mechanisms; or more precisely, with the cells’ protein biosynthesis machinery. Scientists have therefore decided to exploit this potential by using small RNAs against cancer cells or cells damaged in other ways. But the question arises as to how the small RNAs can reach the site where their role is to prevent the generation of dangerous proteins. Dr. Ute Schepers and her team from the Karlsruhe…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/ute-schepers-the-therapeutic-potential-of-small-rnas-and-molecular-transporters
  • Article - 22/08/2011 Lateral view of a four-day-old Pseudomonas aeruginosa biofilm analysed with a confocal laser scanning microscope. The biofilm was stained using fluorescent (live/dead) stains.

    Jörg Overhage investigates how bacteria react to stress

    Bacteria have been around for a very long time and they will probably still be around in the future. They are able to adapt to any factor that is potentially fatal to cells heat hunger radiation toxic chemicals or immune attacks. However tolerance to stress is not only characteristic of individual bacteria bacteria join forces whenever inhospitable conditions arise. A team of researchers led by Dr. Jörg Overhage at the Karlsruhe Institute of…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/joerg-overhage-investigates-how-bacteria-react-to-stress
  • Dossier - 22/08/2011 Volcanic crater in the Yellowstone National Park: The lake is surrounded by an orange ring consisting of algae and bacteria which have become adapted to the extremely high temperatures.<br />

    Stress and molecular defence mechanisms

    Organisms can experience stress from exposure to bacteria and pathogenic fungi; in fact, stress can arise from exposure to any type of environmental influence. As they have evolved, biological cells have developed numerous molecular mechanisms that enable them to survive even in inhospitable conditions. What kind of effects do abiotic stress factors have on plants and human beings? How do cells protect themselves? Are researchers able to increase…

    https:////www.gesundheitsindustrie-bw.de/en/article/dossier/stress-and-molecular-defence-mechanisms
  • Press release - 02/08/2011 The structure of human thymidylate synthase with an inhibitory peptide bound at its dimer interface determined by x-ray crystallography can be seen in a schematic representation.

    New peptides to fight ovarian cancer drug resistance

    Italian and German scientists have designed peptides to target the protein-protein interface of a key enzyme in DNA synthesis crucial for cancer growth. The peptides act by a novel inhibitory mechanism and curb cancer cell growth in drug resistant ovarian cancer cells. The multidisciplinary research project was led by the University of Modena and Reggio Emilia (UNIMORE) and the Heidelberg Institute for Theoretical Studies (HITS).

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/new-peptides-to-fight-ovarian-cancer-drug-resistance
  • Dossier - 04/07/2011 The cement-free Metha® Short Hip Stem prosthesis with Plasmapore® µ-CaP coating of the entire proximal surface supports rapid secondary fixation. µ-CaP is applied on the microporous titanium Plasmapore® surface. It has an osteoconductive effect and accelerates contact between the bone and the prosthesis stem.

    Implants of the future: bioactive, corrosion-resistant and antibacterial

    People’s life expectancy is increasing due to constantly improving medical treatment. One result of this is the greater wear of joints, which then need to be replaced with implants. Increased life expectancy means that the implants remain in the body for much longer and therefore need to be longer lasting. The revision rate of implant materials used in clinical practice is still as much as 10 per cent, particularly in the case of hip and knee…

    https:////www.gesundheitsindustrie-bw.de/en/article/dossier/implants-of-the-future-bioactive-corrosion-resistant-and-antibacterial
  • Article - 04/07/2011 14700_de.jpg

    Stefan Rensing investigates the evolutionary transition from algae to land plants

    The biologist Prof. Dr. Stefan Rensing from the University of Freiburg has been involved in introducing the use of computers to the life sciences from the very beginning. His analyses of the moss genomes now help to close an important gap in evolutionary research how did algae become land plants?

    https:////www.gesundheitsindustrie-bw.de/en/article/news/stefan-rensing-investigates-the-evolutionary-transition-from-algae-to-land-plants
  • Article - 04/07/2011 14640_de.jpg

    The adhesion of cells to the endothelium and to artificial surfaces

    Professor Stefan W. Schneider from the Mannheim Medical Faculty is investigating the function of the vascular endothelium and its interaction with blood and tumour cells using microfluidics methods that enable him to measure the adhesion of cells to the walls of blood vessels under physiological flow conditions. As part of an interdisciplinary project, he is investigating the characteristics of wafer-thin surfaces covered with living cells, which…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/the-adhesion-of-cells-to-the-endothelium-and-to-artificial-surfaces
  • Press release - 20/06/2011 07777_de.jpg

    CureVac presents new data for prostate and lung cancer vaccines

    CureVac GmbH presented promising new data for prostate cancer vaccine CV9103 and lung cancer vaccine CV9201 at the ASCO Conference in Chicago. Final trial results confirm safety and excellent antigen-specific immunogenicity of prostate cancer vaccine CV9103. And initial promising data from phase I/IIa trial of lung cancer vaccine CV9201 further supports the potential of CureVac’s RNActive® vaccination technology in cancer immunotherapy and…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/curevac-presents-new-data-for-prostate-and-lung-cancer-vaccines
  • Article - 20/06/2011 14563_de.jpg

    How plants change their shape – researchers at KIT investigate cytoskeletal processes

    Organisms have two possibilities when they encounter inhospitable environmental conditions: to run away or to adapt. As plants have no legs, they therefore need to adapt rapidly to unstable environmental conditions. A plant is hugely flexible in terms of its shape and one of the things that makes this possible is its cytoskeleton, a scaffold consisting of specialized filaments. A group of researchers at the Karlsruhe Institute of Technology (KIT)…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/how-plants-change-their-shape-researchers-at-kit-investigate-cytoskeletal-processes
  • Press release - 19/05/2011

    Curetis AG successfully increases Series A financing round to EUR 24.5 million

    Curetis AG, an innovative molecular diagnostics company focusing on the development and commercialization of in-vitro diagnostic products for infectious diseases, today announced an extension of its Series A financing, bringing the total size of the round to € 24.5 million. CD-Venture joined the funding as a new investor, while all of Curetis' existing VC investors participated in the round. Several private investors also continued to…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/curetis-ag-successfully-increases-series-a-financing-round-to-eur-24-5-million
  • Article - 04/04/2011 14053_de.jpg

    FreiBiotics GmbH – new drugs against resistant bacteria

    Bacteria adapt quickly to their environment and also to antibiotics. Many of the antibiotics used to treat bacterial infections have become ineffective as a great many bacteria have become resistant to them. Freiburg-based FreiBiotics GmbH is looking for completely new classes of antimicrobial substances. A screening method that has been developed over the last few years based on biosensors makes the identification of new substance classes more…

    https:////www.gesundheitsindustrie-bw.de/en/article/news/freibiotics-gmbh-new-drugs-against-resistant-bacteria
  • Press release - 30/03/2011 14044_de.jpg

    Bacteria poison themselves from within

    The research group led by Anton Meinhart at the Max Planck Institute for Medical Research in Heidelberg has shown that proteins from the zeta toxin group trigger a self-destructive mechanism in bacteria. The triggers for this bacterial suicide are toxin/antitoxin systems that play an important role in the hereditary transmission of resistance and virulence genes. The scientists have thus found a valuable new tool for the development of new…

    https:////www.gesundheitsindustrie-bw.de/en/article/press-release/bacteria-poison-themselves-from-within
  • Article - 21/02/2011 13724_de.jpg

    Hope for more effective brain tumour therapy

    Glioblastoma is the most common and most aggressive type of brain tumour in humans. It has a tendency to recur and it carries a bad prognosis. Intensive research into the molecular reaction chains involved in its pathogenesis has led to promising and effective treatment strategies.

    https:////www.gesundheitsindustrie-bw.de/en/article/news/hope-for-more-effective-brain-tumour-therapy

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