Dossier - 16/06/2014 Biotechnology as a tool for the production of food Biotechnology opens up numerous opportunities for the food industry. The targeted use of biotechnological methods can, amongst other things, help reduce the quantity and number of unhealthy ingredients in foods as well as degrade allergenic substances. Genomic research and targeted breeding also greatly facilitate progress in agriculture. Food biotechnology therefore contributes significantly to saving resources, optimising harvest yields and…https:////www.gesundheitsindustrie-bw.de/en/article/dossier/biotechnology-as-a-tool-for-the-production-of-food
Article - 18/08/2016 Moonlighting proteins can make bacteria pathogenic The mechanism underlying the export of biomolecules from cells remains unknown. Prof. Dr. Friedrich Götz and his team at the Institute of Microbial Genetics at the University of Tübingen have found out that staphylococci can turn into dangerous pathogens by excreting normally harmless enzymes. The researchers believe that the enigmatic excretion of such enzymes is due to a completely new mechanism and are thus planning to carry out further…https:////www.gesundheitsindustrie-bw.de/en/article/news/moonlighting-proteins-can-make-bacteria-pathogenic
Dossier - 02/06/2014 Bioanalysis – techniques for the characterization of biological material Science constantly provides researchers with new challenges biologists and bioanalysts have to deal with and which come from sources as varied as the ever increasing number of resistant pathogenic bacterial strains or the famine conditions in Third-World countries. In the search for scientific truths bioanalysis is the development optimization and application of the entire range of analytical methods available. However we need to keep in mind…https:////www.gesundheitsindustrie-bw.de/en/article/dossier/bioanalysis-techniques-for-the-characterization-of-biological-material
Press release - 21/05/2010 The molecular network of “death receptors” on trial The international ApoNET research project, which is part of a European-wide systems biology initiative, is coordinated by the Mannheim Medical Faculty at the University of Heidelberg. ApoNET researchers use modern genome sequencing methods and computer models to gain a better understanding of apoptosis networks in liver cells. The project is funded by the German Federal Ministry of Education and Research and the European Union with 1.7 million…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/the-molecular-network-of-death-receptors-on-trial
Press release - 04/11/2010 Death Signal for Brain Tumor Cells A protein which acts as a danger signal in the body causes an unknown form of cell death in malignant brain tumors. This process is characterized by the formation of giant mitochondria in the dying cells. This has been discovered by scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Institute of Pathology of Heidelberg University. Healthy brain cells, by contrast, are resistant to this form of cell…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/death-signal-for-brain-tumor-cells
Dossier - 30/04/2012 Human infectious diseases: new threats The serious EHEC outbreak in Germany in 2011, the 2009 swine flu pandemic, the bird flu pandemic in 2005 and 2006 and the SARS outbreak in China in 2003, all of which have fuelled the fear of devastating epidemics for many people in Germany, have fortunately all been contained – at least up until now. However, experts warn of new dangerous pathogens that are spreading as a result of globalization and global climate warming. This is leading to new…https:////www.gesundheitsindustrie-bw.de/en/article/dossier/human-infectious-diseases-new-threats
Article - 30/06/2016 Why fasting is good for health A protein in the nucleus of liver cells is produced in greater quantities when we go hungry; it limits fatty acid uptake and adjusts the metabolism in the liver. However in people with metabolic disorders, the abnormal expression of this protein (GADD45β), which was previously only known to be involved in the regulation of cell division and DNA repair, leads to a dysregulated fat and sugar metabolism. Scientists from the DKFZ and Helmholtz…https:////www.gesundheitsindustrie-bw.de/en/article/news/why-fasting-is-good-for-health
Press release - 20/09/2012 Discus throw with cancer signals The Wnt signaling protein plays an important part in embryonic development and also in the development of diseases such as cancer. It has been unknown until now just how Wnt is carried from cell to cell. Scientists of the German Cancer Research Center and Medical Faculty Mannheim of Heidelberg University have now discovered that the protein is shipped on small discus-shaped vesicles called exosomes. The researchers are now investigating whether…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/discus-throw-with-cancer-signals
Press release - 08/01/2009 ILM – Laser-assisted preventive and curative dental treatment In cooperation with numerous industrial partners and with the support of public funds, researchers at the ILM are focusing on the optimisation of sealer materials and remineralisation substances as well as on effective and permanent preventive caries treatment. https:////www.gesundheitsindustrie-bw.de/en/article/press-release/ilm-laser-assisted-preventive-and-curative-dental-treatment
Article - 15/12/2014 From HIV structure to new AIDS therapies The building blocks of the viral protein capsid are rearranged as HI viruses mature into infectious AIDS-causing agents. Researchers from Heidelberg have made these structural changes visible on the molecular level. The findings could potentially be used for developing much-needed new AIDS therapeutics.https:////www.gesundheitsindustrie-bw.de/en/article/news/from-hiv-structure-to-new-aids-therapies
Article - 25/02/2013 Computomics: unlocking the secrets of plant genome sequences Thanks to the latest generation of sequencing technology, the deciphering of the complete genome of organisms is becoming faster and cheaper. The challenge is to compile the book of life from millions of DNA fragments and unlock the secrets of the human and other organisms. The young bioinformatics company Computomics in Tübingen is doing just this for crops. In contrast to the human genome, the genome of the majority of plants is still a book…https:////www.gesundheitsindustrie-bw.de/en/article/news/computomics-unlocking-the-secrets-of-plant-genome-sequences
Press release - 01/09/2020 Strengthening the immune system with small molecules Infections pose an increasing risk to hospitalized patients. In collaboration with a number of partners, the Fraunhofer IGB has developed a new therapeutic approach as part of the InnateFun project. Their strategy is to improve cells’ ability to defend themselves against harmful microorganisms by acting on their immune receptors. The researchers’ work on this therapeutic approach has reached the animal model stage. https:////www.gesundheitsindustrie-bw.de/en/article/press-release/strengthening-immune-system-small-molecules
Article - 18/05/2013 Biofilm research aims at fighting hospital germs Pseudomonas aeruginosa is a common bacterium that can be found in many different places – soil, water, washing basins, toilets and washing machines, to name but a few examples. Due to its resistance to antibiotic treatment, P. aeruginosa is mainly known as the cause of hospital-acquired infections. David Schleheck, a biologist from Konstanz University, deals specifically with the bacterium’s presence in biofilms. His research could open up new…https:////www.gesundheitsindustrie-bw.de/en/article/news/biofilm-research-aims-at-fighting-hospital-germs
Article - 19/03/2012 Soil bacteria to produce new antibiotics An ever-growing number of genomes of soil bacteria of the genus Streptomyces are being sequenced. Using a method known as “genome mining”, researchers at the University of Tübingen are working on the identification of gene clusters that have the potential to be used in industrial biotechnology for the production of new antibiotics and other pharmaceutically active substances. To achieve this, the biosynthesis gene clusters are integrated into…https:////www.gesundheitsindustrie-bw.de/en/article/news/soil-bacteria-to-produce-new-antibiotics
Press release - 22/06/2009 Many animal experiments are superfluous Researchers at the Esslingen University of Applied Sciences are working on an alternative to the large number of animal experiments that are still being carried out. Researchers under the leadership of Prof. Dr. Bettina Weiß have received a grant from the Landesstiftung Baden-Württemberg foundation for work on this particular research area.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/many-animal-experiments-are-superfluous
Article - 26/04/2016 Methadone for cancer treatment? Clinical trials are needed to prove the effectiveness of this opioid Claudia Friesen, an oncologist at Ulm University Hospital, has achieved what many scientists dream of: she has made a discovery that has increased existing knowledge, and can be used to help people. People with cancers that are resistant to all conventional therapies who have been given methadone for pain relief in combination with conventional chemo- or radiation therapy, have reported that tumours have shrunk or disappeared completely. Clinical…https:////www.gesundheitsindustrie-bw.de/en/article/news/methadone-for-cancer-treatment-clinical-trials-are-needed-to-prove-the-effectiveness-of-this-opioid
Article - 02/07/2009 A virus that hides while it waits for an opportunity to replicate Thomas Mertens, Medical Director of the Institute of Virology in Ulm, has a strong scientific and clinical interest in the human cytomegalovirus (HCMV), a big virus with a big impact which, despite its size, is overshadowed by known viruses such as the HI virus that is the object of research for Mertens’ colleagues. HCMV research is a challenging area where quick successes are rare.https:////www.gesundheitsindustrie-bw.de/en/article/news/a-virus-that-hides-while-it-waits-for-an-opportunity-to-replicate
Press release - 06/02/2008 CSS-Systemhaus Schlegel: Plant cultures with an electronic identity card A software developed by the Stuttgart-based Systemhaus Schegel covers all activities related to administering cultures it guarantees the foolproof production and propagation of plants and when printed out on a thermal printer incorporates all the necessary information on a barcode label.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/css-systemhaus-schlegel-plant-cultures-with-an-electronic-identity-card
Article - 23/07/2009 Making cancer cells commit suicide They divide and divide, and no natural border can stop them. Tumours such as the Ewing sarcoma, a bone cancer that occurs predominantly in teenagers, grow incessantly, making treatment difficult. A few years ago, Prof. Dr. Udo Kontny and his team from the University Hospital in Freiburg discovered a way to stop the growth of this particular tumour by activating a switch on the surface of cells which induces cellular death. Can physicians learn to…https:////www.gesundheitsindustrie-bw.de/en/article/news/making-cancer-cells-commit-suicide
Press release - 24/09/2009 Evidence for the expression of both DNA strands A group of researchers led by Prof. Hess at the University of Freiburg reports on the use of both strands of the DNA double helix during the copying of the genetic information encoded by the genes. As reported in the renowned scientific magazine Molecular Systems Biology, the antisense RNA created during this process can contribute to the development of new therapeutic concepts.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/evidence-for-the-expression-of-both-dna-strands
Article - 10/06/2014 Ribosome assembly as target for innovative antibiotics Although bacterial ribosomes are a popular target of common antibiotics, there are no drugs that specifically target ribosome assembly. To date, there is simply no screening method that would be suitable for assaying inhibitors of ribosomal subunit assembly. Prof. Dr. Elke Deuerling and Dr. Rainer Nikolay from the University of Konstanz have now achieved a breakthrough. They have developed a method that enables the high-throughput identification…https:////www.gesundheitsindustrie-bw.de/en/article/news/ribosome-assembly-as-target-for-innovative-antibiotics
Article - 07/01/2008 Fighting an unknown killer with knowledge In Germany every year 800000 people contract community acquired pneumonia and 50000 die of it. A new foundation based in Ulm is hoping to contribute to a better understanding of this unpleasant disease and to improve the therapy to combat it.https:////www.gesundheitsindustrie-bw.de/en/article/news/fighting-an-unknown-killer-with-knowledge
Press release - 13/05/2020 Drug counterfeiters use fear of corona epidemic Falsified chloroquine tablets identified in Africa - University of Tübingen supports local pharmacists in the analysis.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/arzneimittelfaelscher-nutzen-angst-vor-corona-epidemie
Press release - 31/01/2012 HITS Scientist Rebecca Wade receives professorship at the University of Heidelberg Today, Dr. Rebecca Wade, head of the “Molecular and Cellular Modelling” research group at the Heidelberg Institute for Theoretical Studies (HITS), has been appointed to the W3 professorship “Computational Structural Biology” (Faculty of Biosciences/HITS) at the University of Heidelberg.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/hits-scientist-rebecca-wade-receives-professorship-at-the-university-of-heidelberg
Article - 14/11/2011 Marina Freudenberg and Chris Galanos – more than 40 years of bacterial defence research This years Nobel Prize in Medicine or Physiology was awarded to three renowned scientists one of whom is the American Bruce Beutler who was instrumental in clarifying the structure of the mammalian Toll-like 4 TLR4 receptor. Prof. Dr. med. Marina Freudenberg and Dr. Dr. h.c. Chris Galanos from the Freiburg-based Max Planck Institute MPI of Immunobiology and Epigenetics have co-authored the key publication that led to the award of the Nobel Prize…https:////www.gesundheitsindustrie-bw.de/en/article/news/marina-freudenberg-and-chris-galanos-more-than-40-years-of-bacterial-defence-research