Value-based healthcare - 11/01/2023

High-quality healthcare pays off

High-quality medical treatment is not only worthwhile for ill persons. The Division of Health Economics at the German Cancer Research Center in Heidelberg, headed up by Prof. Dr. Michael Schlander, together with researchers from Dresden, has carried out a cost-effectiveness analysis that shows that certified colon cancer centres provide not only better but also more cost-effective care than other clinics.

CureVac N.V. (Nasdaq: CVAC), a global biopharmaceutical company developing a new class of transformative medicines based on messenger ribonucleic acid (“mRNA”), today announced positive preliminary data from ongoing Phase 1 clinical programs in COVID-19 and seasonal flu, assessing both modified and unmodified mRNA technology. The tested vaccine candidates are being developed in collaboration with GSK.

Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important role in medical research. A previously unexplained process in the complex mitochondria was the formation of their barrel pores.

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim* and the University Medical Center Hamburg Eppendorf has now identified an enzyme that controls the activity of osteoblasts.

Heidelberg scientists decode the genetic foundations of rapid testicle evolution in mammals and humans. Evolutionary pressure across male mammals to guarantee the procreation of their own offspring led to a rapid evolution of the testicle.

Inhibition of a protein complex in cells of the immune system prevents rejection of transplanted organs – this has been shown in a study by immunologists from the University of Konstanz, the Biotechnology Institute Thurgau (BITg) and Chongqing Cancer University Hospital.

A polyester plastic of great mechanical stability, which is also easily recyclable and even compostable: Stefan Mecking, chemist at the University of Konstanz, and his research group present a new material.

A polyester plastic of great mechanical stability, which is also easily recyclable and even compostable: Stefan Mecking, chemist at the University of Konstanz, and his research group present a new material.

Start-up 'Innovation Matters' - 19/12/2022

Saffron cultivation in Germany - sustainable with support from robots

Saffron is one of the most expensive spices in the world, because picking it involves a complex manual process. This treasure therefore comes to us mostly from countries such as Iran with poor working conditions and low wages. A start-up company called Innovation Matters from Baden-Württemberg is now developing a robot-assisted, automated process that will make saffron cultivation attractive in Germany as well as ecological and fair.

The launch of the global Nature Positive Universities initiative was announced at the UN Biodiversity Conference (COP 15), held in Montreal, Canada, in December 2022. The University of Konstanz is one of more than one hundred universities from all five continents joining the initiative. The common goal is to address the university's own impact on nature and to identify and implement effective measures to halt and reverse the loss of…

On December 13, 2022, the European Commission granted approval to a drug against metastatic prostate cancer whose active ingredient was developed under the leadership of the German Cancer Research Center (DKFZ) in collaboration with Heidelberg University Hospital and Heidelberg University. The drug can significantly improve the survival chances of patients.

Neurodegenerative diseases - 12/12/2022

Blood-based biomarkers allow the early prediction of Alzheimer's risks

Most dementia diseases develop insidiously and are only detected at an advanced stage. Researchers at the University of Heidelberg and the German Cancer Research Center (DKFZ) have now identified the glial fibre acidic protein (GFAP) in the blood as a promising biomarker that can be used to determine an increased risk of developing Alzheimer's disease up to 17 years before diagnosis.

Project FuTuReS - 12/12/2022

Microalgae - high-quality products for domestic agriculture?

Algae are aquatic organisms that flourish in a huge variety of species. But that's not all: they are also small green mini-factories that can produce all kinds of valuable materials. All they need is water, light, CO2 and a few nutrients that can be recycled from biogas or sewage treatment plants. Researchers have now determined the optimal framework conditions and practicability of process methods for agricultural algae cultivation.

AI & robotics from the University of Hohenheim advance environmental protection & sustainability in agriculture / German Chancellor Scholz impressed by potential of Swabian multi-talent robot

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found an epigenetic switch in blood stem cells and progenitor cells of mice that can trigger the switch from one mode to the other.

Tübingen biotechnologist Lars Angenent is being awarded the Leibniz Prize by the German Research Foundation (DFG) in appreciation of his outstanding work in the field of environmental biotechnology, it was announced in Bonn on Thursday. The DFG said: “In view of climate change and the resulting need to develop a sustainable food, chemistry and energy economy, his work is highly relevant.”

Tübingen biotechnologist Lars Angenent is being awarded the Leibniz Prize by the German Research Foundation (DFG) in appreciation of his outstanding work in the field of environmental biotechnology, it was announced in Bonn on Thursday. The DFG said: “In view of climate change and the resulting need to develop a sustainable food, chemistry and energy economy, his work is highly relevant.”

The German Research Foundation (DFG) has awarded the 2023 Gottfried Wilhelm Leibniz Prize to Prof. Achim Menges, head of the Institute for Computational Design and Construction at the University of Stuttgart. The award, which is endowed with EUR 2.5 million, is considered by many the most important research prize in Germany.

The German Research Foundation (DFG) has awarded the 2023 Gottfried Wilhelm Leibniz Prize to Prof. Achim Menges, head of the Institute for Computational Design and Construction at the University of Stuttgart. The award, which is endowed with EUR 2.5 million, is considered by many the most important research prize in Germany.

An interdisciplinary research team at the University of Freiburg has found important clues about the functioning of the sensorimotor cortex. The new findings on neuronal activities in this brain area could be helpful for the further development and use of so-called neuroprostheses. These have an interface with the nervous system and are intended to help compensate for neuronal dysfunctions.

The newborn's immune system is suddenly confronted with microorganisms, food and numerous environmental influences at birth. How do the baby's immune cells prepare for this moment during pregnancy and birth? How do external influences shape the immune system immediately after birth? And what influence does an event like a premature birth have?

European Bioplastics (EUBP) begrüßt die von der Europäischen Kommission verabschiedeten Entwürfe für neue Verpackungs- und Biokunststoffvorschriften. „Wir begrüßen das erste umfassende politische Rahmenwerk der Kommission für innovative Biokunststoffe, das deren Potenzial für einen positiven Beitrag zur Umwelt anerkennt.

Find companies that already offer fossil carbon free products, made from biomass, CO2 and recycling

With insects to the circular economy - 30/11/2022

InBiRa: Insect biorefinery turns food leftovers into new products

Insect larvae can convert food leftovers and waste into secondary raw materials for technical products and cosmetics. Researchers are looking to establish an insect biorefinery for this purpose at the Fraunhofer IGB in Stuttgart. The InBiRa project is financed with a total of 3.8 million euros in EU and Baden-Württemberg state funding.

BioMonitor addresses the information gap in bioeconomy research by re-structuring existing data and modelling framework. After more than four years of great scientific collaboration, the 17 partners share their results.

A tasty dish for chickens: Researchers from the University of Hohenheim in Stuttgart were able to feed the animals the first 50 kilos of protein extract that were obtained from pasture. Yet the plants found in fields and meadows offer much more than a new source of protein for pigs and poultry: They could also constitute an alternative to soy for human nutrition. They also form a basis for organic-based plastics and paper, energy, and…

Chemical building blocks from plastic waste; Reducing the risk of falls using virtual orientation aids: Konstanz chemists Manuel Häußler and Lukas Odenwald as well as sport scientist Lorenz Assländer receive Baden-Württemberg prototype funding for their transfer projects "Waste2DCA" and "Augmented Balance".

Chemical building blocks from plastic waste; Reducing the risk of falls using virtual orientation aids: Konstanz chemists Manuel Häußler and Lukas Odenwald as well as sport scientist Lorenz Assländer receive Baden-Württemberg prototype funding for their transfer projects "Waste2DCA" and "Augmented Balance".

Press release - 29/11/2022

Five European pilot regions are joining forces for the bioeconomy

BIOPRO Baden-Württemberg participates in the Horizon Europe ROBIN project to improve the participation of regional bioeconomy strategies and related policies across Europe.

Press release - 29/11/2022

Five European pilot regions are joining forces for the bioeconomy

BIOPRO Baden-Württemberg participates in the Horizon Europe ROBIN project to improve the participation of regional bioeconomy strategies and related policies across Europe.

What a success for Ulm University and its medical centre! The German Research Foundation (Deutsche Forschungsgemeinschaft; DFG) extends the Collaborative Research Centre (CRC) on Trauma Medicine for the second time. The third funding phase infuses the CRC 1149 'Danger Response, Disturbance Factors and Regenerative Potential after Acute Trauma' with 11.1 million euros.

The Bundesanstalt für Materialforschung und -prüfung (BAM) is developing a more sustainable process to produce active pharmaceutical ingredients in a major EU project: The pilot project is intended to demonstrate the advantages of mechanochemistry for more environmentally friendly and CO2-neutral pharmaceutical production.

Researchers of the University of Freiburg introduce biosensor for the nucleic acid amplification-free detection of SARS-CoV-2 RNA.

Start-up Actimi GmbH - 23/11/2022

Real-time telemonitoring of heart failure

Improved quality of life for patients and lower costs for health insurers: these are the advantages of telemonitoring patients with advanced heart failure. The Stuttgart-based start-up Actimi offers an all-in-one platform for those who treat and those who suffer from the disease.

BioFluidix GmbH, a spin-off resulting from the cooperation between Hahn-Schickard and the Department of Microsystems Engineering at the University of Freiburg, is now part of the Swiss Hamilton Bonaduz AG.

DZNE researchers discover link between the protein medin and Alzheimer's disease. The protein medin is deposited in the blood vessels of the brains of Alzheimer's patients along with the protein amyloid-β. DZNE Researchers have discovered this so-called co-aggregation. They have now published their observation in the renowned journal Nature.

MEDICA and COMPAMED continue to develop in an extremely vital manner. The world's leading medical trade fair and the international No. 1 for the medical technology supply sector once again impressively underscored their positive results from the previous year with strong numbers – despite continuing adverse conditions. A significant increase in bookings on the part of the exhibiting companies was followed after four days by a marked increase…

Optical technologies & artificial intelligence: University of Hohenheim, Bosch, Amazonen-Werke, and BASF Digital Farming conducts research into high-performance sensors for smart herbicide treatment

Optical technologies & artificial intelligence: University of Hohenheim, Bosch, Amazonen-Werke, and BASF Digital Farming conducts research into high-performance sensors for smart herbicide treatment

From human intestines to the bottom of the sea: Microorganisms populate nearly any habitat, no matter how hostile it is. Their great variety of survival strategies is of huge potential in biotechnology. Most of these organisms, however, are unknown, because they cannot be cultivated.

Using animal-free methods to assess the hazard potential of chemicals to the nervous system of unborn children? An international research team including toxicologists from Konstanz and Düsseldorf has developed a testing battery based on human cells that has the potential to replace traditional methods for assessing developmental neurotoxicity.

Festo’s high-tech bioreactor - 10/11/2022

Valuable materials of all kinds - produced automatically in living cells

In future, algae could be used to produce practically everything that still requires petroleum, including plastics, fuels, medicines and food. Algae are also climate savers par excellence, because they bind ten times more CO2 than terrestrial plants. Festo, a company based in Esslingen, Germany, has developed a high-tech bioreactor that can be used to automatically cultivate the small green biofactories - and that do so a hundred times more…

Climate protection and sustainability in hospitals - 09/11/2022

Sustainable activities in the healthcare sector

The healthcare sector is not only facing major challenges in dealing with the consequences of climate change on human health, but it also needs to make a concrete contribution to reducing its own greenhouse gas emissions. Analyses show there are many opportunities to make medical care more sustainable, especially in hospitals’ daily routines. This is where the Heidelberg University Hospital and the viamedica foundation from Freiburg come in.

Climate protection and sustainability in hospitals - 09/11/2022

Sustainable activities in the healthcare sector

The healthcare sector is not only facing major challenges in dealing with the consequences of climate change on human health, but it also needs to make a concrete contribution to reducing its own greenhouse gas emissions. Analyses show there are many opportunities to make medical care more sustainable, especially in hospitals’ daily routines. This is where the Heidelberg University Hospital and the viamedica foundation from Freiburg come in.

Climate protection and sustainability in hospitals - 09/11/2022

Sustainable activities in the healthcare sector

The healthcare sector is not only facing major challenges in dealing with the consequences of climate change on human health, but it also needs to make a concrete contribution to reducing its own greenhouse gas emissions. Analyses show there are many opportunities to make medical care more sustainable, especially in hospitals’ daily routines. This is where the Heidelberg University Hospital and the viamedica foundation from Freiburg come in.

Climate protection and sustainability in hospitals - 09/11/2022

Sustainable activities in the healthcare sector

The healthcare sector is not only facing major challenges in dealing with the consequences of climate change on human health, but it also needs to make a concrete contribution to reducing its own greenhouse gas emissions. Analyses show there are many opportunities to make medical care more sustainable, especially in hospitals’ daily routines. This is where the Heidelberg University Hospital and the viamedica foundation from Freiburg come in.

Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease. The new technology can trace which populations of breast cancer cells are responsible for the spread of the disease, and for the first time highlights how the location of cancer cells could be as important as mutations in tumor growth The new study is…

The health of nerve cells is closely linked to the auxiliary cells that surround them, the so-called glial cells. It still remains largely unknown what role glial cells play in age-related diseases.

During the growth and development of living organisms, different types of cells must come into contact with each other in order to form tissues and organs together. A small team working with Prof. Dr. Anne Classen of the Excellence Cluster CIBSS of the University of Freiburg has discovered that complex changes in form, or morphogenesis, during development are driven exclusively via the affinity of cells to each other.

Toxicologists from the University of Konstanz have found that the protein p53 continuously protects our cells from tumorigenesis by coordinating important metabolic processes that stabilize their genomes.

Whether in drinking water, food or even in the air: plastic is a global problem - and the full extent of this pollution may go beyond of what we know yet. Researchers at the Karlsruhe Institute of Technology (KIT), together with partners from the Netherlands and Australia, have reviewed conventional assumptions for the transport of plastic in rivers.

The University of Stuttgart's MobiLab Real-World Laboratory aims to make Campus Vaihingen car- and emission-free. Research areas include autonomous vehicles and inductive charging while driving. In addition, MobiLab is helping to ensure that the University of Stuttgart will also be climate-neutral in the area of mobility and transport by 2030.

What will the energy systems of the future look like? What technical foundations do we need, and how can the upcoming transformation be shaped in such a way that we involve all actors in society? Answers to such questions are to be provided by four research projects funded by the Carl Zeiss Foundation (CZS) as part of the “CZS Breakthroughs – Energy Systems of the Future” program. One of these is based at the University of Stuttgart.

Viral cancer therapy - 26/10/2022

Therapeutic viruses against tumours and metastases

Viruses can overcome cell barriers and transfer information to their host cells. They know how to make their host cell’s infrastructure work for them. This makes them excellent biotechnological tools, which a research group from the Fraunhofer IGB in Stuttgart is using to its advantage. The team is developing a therapeutic virus that not only recognises and fights tumours, but also has the potential to reach metastases.

Heidelberg University scientists are to receive three ERC Synergy Grants – three highly endowed grants of the European Research Council – for pioneering research projects by several teams working in collaboration.

Why do metastases often only appear after the original tumor has been surgically removed? Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Mannheim Medical Faculty of Heidelberg University have now published an explanation for this phenomenon. They were able to identify a messenger substance of the cancer cells that locally promotes the growth of the primary tumor.

Remaining mobile and producing without overtaxing the earth’s natural regenerative capacity: That’s the aim of the Innovation Campus “Mobility of the Future” (ICM) at the Karlsruhe Institute of Technology (KIT) and the University of Stuttgart. Here, in about 60 research projects and 40 research institutes, almost 300 scientists are working on electric motors without rare earths, novel manufacturing technologies, and self-learning software systems…

Mobil bleiben und produzieren, ohne die natürliche Regenerationsfähigkeit der Erde zu überfordern, das ist der Anspruch des InnovationsCampus Mobilität der Zukunft (ICM) am Karlsruher Institut für Technologie und der Universität Stuttgart. Fast 300 Forschende in gut 60 Forschungsprojekten und 40 -instituten arbeiten hier an Elektromotoren ohne Seltene Erden, neuartigen Fertigungstechnologien und selbstlernenden Software-Systemen für Fahrzeuge.

The Carl Zeiss Foundation is funding the "DELIVER - Data-driven Engineering of Sustainable Living Materials" project at the University of Freiburg in its "CZS Wildcard" program. In the project, scientists from the Freiburg Clusters of Excellence CIBSS and livMatS will develop sustainable wood-based materials whose properties can be precisely controlled.

The Carl Zeiss Foundation is funding the "DELIVER - Data-driven Engineering of Sustainable Living Materials" project at the University of Freiburg in its "CZS Wildcard" program. In the project, scientists from the Freiburg Clusters of Excellence CIBSS and livMatS will develop sustainable wood-based materials whose properties can be precisely controlled.

Researchers of the University of Freiburg have discovered a previously unknown function of septins in defending cells against dangerous hospital pathogens.

University of Tübingen, a leading member of Cyber Valley, Europe’s largest Artificial Intelligence (AI) research consortium and Boehringer Ingelheim launch an AI and data science fellowship program for top talents from around the world. Three to five fellowships will be awarded per year for up to three years with a target of nine to fifteen fellows in the program after five years.

Apogenix, a biopharmaceutical company developing next generation immunotherapeutics, announced today that asunercept showed statistically significant benefits for hospitalized COVID-19 patients in the ASUNCTIS trial. The open-label multi-center phase II trial investigated efficacy and safety of asunercept in 435 patients with moderate to severe COVID-19 disease.

Researchers from Freiburg and Harvard publish the three-dimensional structure of the B cell antigen receptor, shedding new light on its composition.

Dossier - 19/10/2022

More food sustainability: crucial for people and for the environment

Strawberries in winter and imported apples? You can find them in most supermarkets. This is not sustainable. Looking to the future, the way we eat needs to change in many mundane ways – and this needs to happen quickly so that future generations will also be able to enjoy a planet that is worth living on. In Baden-Württemberg, alternative nutrition concepts are being worked at pace. Many creative ideas and innovative products already exist.

Dossier - 12/10/2022

The health sector must become greener

Worldwide, the health sector is struggling with the consequences of global warming, but fatally is itself responsible for a significant proportion of greenhouse gas emissions. Studies show that hospitals and rehabilitation clinics in particular have great potential for reducing these emissions and, like the manufacturing industry, need to fundamentally revise established processes.

Across the EU, more than 300 billion items of packaging are not recycled every year because they consist of a mixture of different materials. Monomaterial packaging on the other hand is easy to recycle. However, it needs to be coated with ultra-thin barrier layers to protect delicate products just as well as compound materials do.

Across the EU, more than 300 billion items of packaging are not recycled every year because they consist of a mixture of different materials. Monomaterial packaging on the other hand is easy to recycle. However, it needs to be coated with ultra-thin barrier layers to protect delicate products just as well as compound materials do.

More animal welfare and better animal health, more climate protection and less environmental impact: Researchers at the University of Hohenheim in Stuttgart are pursuing these goals with a new approach: They are exploring the interplay between farm animals and the millions of microorganisms in the animals’ digestive tracts. The federal and state governments are supporting the university with the construction of a unique research center for around…