With the "Česká Hlava" awards, the Czech government has been honoring the country's most brilliant minds every year since 2002 and recognizing exceptional achievements in research, development and innovation. Martina Benešová-Schäfer of the German Cancer Research Center was among the six laureates honored in 2022 at Charles University in Prague.

After infections or blood loss, the body must compensate for the loss of blood cells as quickly as possible. This has long been considered the task of the hematopoietic stem cells in the bone marrow. But scientists at the German Cancer Research Center (DKFZ) have now discovered in mice that a certain population of progenitor cells takes over this task: This accelerates the regeneration of the blood cells.

Acute Graft-versus-host disease (GvHD) is a life-threatening complication after leukemia treatment with allogeneic stem cell transplantation i.e. the transplantation of cells from another person. GvHD occurs when the transplanted immune cells are overly active and damage the receiving patient's healthy tissue. Researchers found that an endogenous molecule can mitigate this misdirected immune response.

The hospital pathogen Pseudomonas aeruginosa requires the sugar-binding proteins LecA and LecB to form biofilms as well as to attach to and penetrate host cells. These so-called lectins are therefore suitable targets for active substances to combat Pseudomonas infections. Researchers from Saarbrücken and Freiburg have now produced potent inhibitors for LecA and LecB that are more stable and soluble than previous drug candidates.

Press release - 16/01/2023

GoDanuBio’s contribution to the bioeconomisation of the Danube Region

GoDanuBio supported the set-up of policy frameworks and participative governance schemes in the participating regions. The main topics were circular bioeconomy, sustainable rural development and rural-urban interactions.

Researchers at the University of Freiburg Medical School led by Prof. Dr. Johannes Letzkus and the Max Planck Institute for Brain Research have discovered that a little-studied area of the brain, the "zone of uncertainty" or "zona incerta," communicates with the neocortex in unconventional ways to rapidly control memory formation.

Valorization of biological materials - 12/01/2023

ValBio-Urban brings bioeconomy research to users

Reducing carbon dioxide emissions and the capture and utilization of CO2 are important steps towards achieving a climate-neutral and sustainable economy. Accordingly, as part of the ValBio-Urban research project, an interdisciplinary team from the University of Stuttgart is developing bioeconomic approaches to solutions that will be implemented with companies from Baden-Württemberg.

Using new microscopic methods in combination with machine learning-based image analysis, researchers from Freiburg have discovered new structures on the surface of living B cells that affect the distribution and possibly the function of their antigen receptors. The researchers' study has been published in The EMBO Journal.

Value-based healthcare - 11/01/2023

High-quality healthcare pays off

High-quality medical treatment is not only worthwhile for ill persons. The Division of Health Economics at the German Cancer Research Center in Heidelberg, headed up by Prof. Dr. Michael Schlander, together with researchers from Dresden, has carried out a cost-effectiveness analysis that shows that certified colon cancer centres provide not only better but also more cost-effective care than other clinics.

CureVac N.V. (Nasdaq: CVAC), a global biopharmaceutical company developing a new class of transformative medicines based on messenger ribonucleic acid (“mRNA”), today announced positive preliminary data from ongoing Phase 1 clinical programs in COVID-19 and seasonal flu, assessing both modified and unmodified mRNA technology. The tested vaccine candidates are being developed in collaboration with GSK.

Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important role in medical research. A previously unexplained process in the complex mitochondria was the formation of their barrel pores.

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim* and the University Medical Center Hamburg Eppendorf has now identified an enzyme that controls the activity of osteoblasts.

Heidelberg scientists decode the genetic foundations of rapid testicle evolution in mammals and humans. Evolutionary pressure across male mammals to guarantee the procreation of their own offspring led to a rapid evolution of the testicle.

Inhibition of a protein complex in cells of the immune system prevents rejection of transplanted organs – this has been shown in a study by immunologists from the University of Konstanz, the Biotechnology Institute Thurgau (BITg) and Chongqing Cancer University Hospital.

A polyester plastic of great mechanical stability, which is also easily recyclable and even compostable: Stefan Mecking, chemist at the University of Konstanz, and his research group present a new material.

A polyester plastic of great mechanical stability, which is also easily recyclable and even compostable: Stefan Mecking, chemist at the University of Konstanz, and his research group present a new material.

Start-up 'Innovation Matters' - 19/12/2022

Saffron cultivation in Germany - sustainable with support from robots

Saffron is one of the most expensive spices in the world, because picking it involves a complex manual process. This treasure therefore comes to us mostly from countries such as Iran with poor working conditions and low wages. A start-up company called Innovation Matters from Baden-Württemberg is now developing a robot-assisted, automated process that will make saffron cultivation attractive in Germany as well as ecological and fair.

The launch of the global Nature Positive Universities initiative was announced at the UN Biodiversity Conference (COP 15), held in Montreal, Canada, in December 2022. The University of Konstanz is one of more than one hundred universities from all five continents joining the initiative. The common goal is to address the university's own impact on nature and to identify and implement effective measures to halt and reverse the loss of…

On December 13, 2022, the European Commission granted approval to a drug against metastatic prostate cancer whose active ingredient was developed under the leadership of the German Cancer Research Center (DKFZ) in collaboration with Heidelberg University Hospital and Heidelberg University. The drug can significantly improve the survival chances of patients.

Neurodegenerative diseases - 12/12/2022

Blood-based biomarkers allow the early prediction of Alzheimer's risks

Most dementia diseases develop insidiously and are only detected at an advanced stage. Researchers at the University of Heidelberg and the German Cancer Research Center (DKFZ) have now identified the glial fibre acidic protein (GFAP) in the blood as a promising biomarker that can be used to determine an increased risk of developing Alzheimer's disease up to 17 years before diagnosis.

Project FuTuReS - 12/12/2022

Microalgae - high-quality products for domestic agriculture?

Algae are aquatic organisms that flourish in a huge variety of species. But that's not all: they are also small green mini-factories that can produce all kinds of valuable materials. All they need is water, light, CO2 and a few nutrients that can be recycled from biogas or sewage treatment plants. Researchers have now determined the optimal framework conditions and practicability of process methods for agricultural algae cultivation.

AI & robotics from the University of Hohenheim advance environmental protection & sustainability in agriculture / German Chancellor Scholz impressed by potential of Swabian multi-talent robot

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found an epigenetic switch in blood stem cells and progenitor cells of mice that can trigger the switch from one mode to the other.

Tübingen biotechnologist Lars Angenent is being awarded the Leibniz Prize by the German Research Foundation (DFG) in appreciation of his outstanding work in the field of environmental biotechnology, it was announced in Bonn on Thursday. The DFG said: “In view of climate change and the resulting need to develop a sustainable food, chemistry and energy economy, his work is highly relevant.”

Tübingen biotechnologist Lars Angenent is being awarded the Leibniz Prize by the German Research Foundation (DFG) in appreciation of his outstanding work in the field of environmental biotechnology, it was announced in Bonn on Thursday. The DFG said: “In view of climate change and the resulting need to develop a sustainable food, chemistry and energy economy, his work is highly relevant.”

The German Research Foundation (DFG) has awarded the 2023 Gottfried Wilhelm Leibniz Prize to Prof. Achim Menges, head of the Institute for Computational Design and Construction at the University of Stuttgart. The award, which is endowed with EUR 2.5 million, is considered by many the most important research prize in Germany.

The German Research Foundation (DFG) has awarded the 2023 Gottfried Wilhelm Leibniz Prize to Prof. Achim Menges, head of the Institute for Computational Design and Construction at the University of Stuttgart. The award, which is endowed with EUR 2.5 million, is considered by many the most important research prize in Germany.

An interdisciplinary research team at the University of Freiburg has found important clues about the functioning of the sensorimotor cortex. The new findings on neuronal activities in this brain area could be helpful for the further development and use of so-called neuroprostheses. These have an interface with the nervous system and are intended to help compensate for neuronal dysfunctions.

The newborn's immune system is suddenly confronted with microorganisms, food and numerous environmental influences at birth. How do the baby's immune cells prepare for this moment during pregnancy and birth? How do external influences shape the immune system immediately after birth? And what influence does an event like a premature birth have?

European Bioplastics (EUBP) begrüßt die von der Europäischen Kommission verabschiedeten Entwürfe für neue Verpackungs- und Biokunststoffvorschriften. „Wir begrüßen das erste umfassende politische Rahmenwerk der Kommission für innovative Biokunststoffe, das deren Potenzial für einen positiven Beitrag zur Umwelt anerkennt.

Find companies that already offer fossil carbon free products, made from biomass, CO2 and recycling

With insects to the circular economy - 30/11/2022

InBiRa: Insect biorefinery turns food leftovers into new products

Insect larvae can convert food leftovers and waste into secondary raw materials for technical products and cosmetics. Researchers are looking to establish an insect biorefinery for this purpose at the Fraunhofer IGB in Stuttgart. The InBiRa project is financed with a total of 3.8 million euros in EU and Baden-Württemberg state funding.

BioMonitor addresses the information gap in bioeconomy research by re-structuring existing data and modelling framework. After more than four years of great scientific collaboration, the 17 partners share their results.

A tasty dish for chickens: Researchers from the University of Hohenheim in Stuttgart were able to feed the animals the first 50 kilos of protein extract that were obtained from pasture. Yet the plants found in fields and meadows offer much more than a new source of protein for pigs and poultry: They could also constitute an alternative to soy for human nutrition. They also form a basis for organic-based plastics and paper, energy, and…

Chemical building blocks from plastic waste; Reducing the risk of falls using virtual orientation aids: Konstanz chemists Manuel Häußler and Lukas Odenwald as well as sport scientist Lorenz Assländer receive Baden-Württemberg prototype funding for their transfer projects "Waste2DCA" and "Augmented Balance".

Chemical building blocks from plastic waste; Reducing the risk of falls using virtual orientation aids: Konstanz chemists Manuel Häußler and Lukas Odenwald as well as sport scientist Lorenz Assländer receive Baden-Württemberg prototype funding for their transfer projects "Waste2DCA" and "Augmented Balance".

Press release - 29/11/2022

Five European pilot regions are joining forces for the bioeconomy

BIOPRO Baden-Württemberg participates in the Horizon Europe ROBIN project to improve the participation of regional bioeconomy strategies and related policies across Europe.

Press release - 29/11/2022

Five European pilot regions are joining forces for the bioeconomy

BIOPRO Baden-Württemberg participates in the Horizon Europe ROBIN project to improve the participation of regional bioeconomy strategies and related policies across Europe.

What a success for Ulm University and its medical centre! The German Research Foundation (Deutsche Forschungsgemeinschaft; DFG) extends the Collaborative Research Centre (CRC) on Trauma Medicine for the second time. The third funding phase infuses the CRC 1149 'Danger Response, Disturbance Factors and Regenerative Potential after Acute Trauma' with 11.1 million euros.

The Bundesanstalt für Materialforschung und -prüfung (BAM) is developing a more sustainable process to produce active pharmaceutical ingredients in a major EU project: The pilot project is intended to demonstrate the advantages of mechanochemistry for more environmentally friendly and CO2-neutral pharmaceutical production.

Researchers of the University of Freiburg introduce biosensor for the nucleic acid amplification-free detection of SARS-CoV-2 RNA.

Start-up Actimi GmbH - 23/11/2022

Real-time telemonitoring of heart failure

Improved quality of life for patients and lower costs for health insurers: these are the advantages of telemonitoring patients with advanced heart failure. The Stuttgart-based start-up Actimi offers an all-in-one platform for those who treat and those who suffer from the disease.

BioFluidix GmbH, a spin-off resulting from the cooperation between Hahn-Schickard and the Department of Microsystems Engineering at the University of Freiburg, is now part of the Swiss Hamilton Bonaduz AG.