Paper technology - 10/03/2021

PLAFCO – a sustainable plastic substitute made from paper

Plastic is indispensable: it is cheap and practical and found in many disposable products such as drinking straws, disposable tableware or even packaging like bonded beverage cartons or bags – and it has a disastrous effect on the environment. The start-up company Plafco Fibertech Oy has developed a sustainable plastic substitute made of paper that could replace many disposable plastic products in the future.

Printing a new cornea during an operation to restore a patient’s eyesight: This groundbreaking step in the fight against corneal disorders is set to become reality with a laser based process using personalized bioink. The method was developed by researchers at the Karlsruhe Institute of Technology (KIT) in collaboration with Carl Zeiss Meditec AG and Evonik Healthcare. Their project won the idea award in this year’s NEULAND innovation contest.

3D tumor models, simulations of drug responses or plant stems used for testing heart stents: the 3R-BioMedicUS center at the University of Stuttgart is developing innovative biomedical approaches to improve preclinical studies, to be seen in the new video.

The University of Stuttgart is contributing to innovations for climate protection as part of the EU project "Smart Circular Bridge". An old material is being rediscovered: flax has been with us for thousands of years in the form of clothing, sacks, and robust ship's ropes. Now the plant fibres are experiencing a renaissance and could become the building material of the future.

Biosensor for whole blood and exhaled breath analysis - 02/02/2022

Antibiotic detection from whole blood or exhaled breath possible

Incorrectly dosed antibiotics are not only dangerous for patients, but also often the cause of resistant strains of bacteria. Researchers at the University of Freiburg have developed a biosensor to determine the effective amount and thus enable personalised therapy. The biosensor works by rapidly determining small amounts of the substances directly from whole blood or exhaled breath.

In the field of optogenetics, scientists investigate the activity of neurons in the brain using light. A team led by Prof. Dr. Ilka Diester and Dr. David Eriksson from the Optophysiology Laboratory at the University of Freiburg has developed a new method to simultaneously conduct laminar recordings, multifiber stimulations, 3D optogenetic stimulation, connectivity inference, and behavioral quantification on brains.

On February 16, 2023, Baden-Württemberg’s Minister of Science, Research and the Arts, Petra Olschowski, visited the University of Freiburg. The focus of her visit was on sustainability and the transfer of knowledge. The minister learned all about how the day-to-day running of the university is becoming sustainable, and the wide-ranging climate protection and environmental safety measures. She also visited the livMatS pavilion.

ProGrün project - 30/12/2023

Using proteins extracted from grassland cuttings to produce animal feed and exploit by-product streams

Animal feed often contains protein from soy and importing it causes major environmental harm. In the ProGrün project, researchers at the University of Hohenheim, including a work group led by Prof. Dr. Andrea Kruse, are developing a scalable technological process to extract proteins from grassland cuttings and use them to make sustainable animal feed produced in the region where it will be used.

Using animal-free methods to assess the hazard potential of chemicals to the nervous system of unborn children? An international research team including toxicologists from Konstanz and Düsseldorf has developed a testing battery based on human cells that has the potential to replace traditional methods for assessing developmental neurotoxicity.

With its "Proof of Concept" grants, the European Research Council ERC supports scientists in further developing the commercial potential of their research results. Nina Papavasiliou from the DKFZ is now receiving the prestigious grant for the second time: she wants to advance the development of a "molecular delivery service" that ensures that therapeutic genes reach the right address in the body in a targeted manner.

Detecting drug resistance of tumour cells - 25/05/2023

AI-assisted diagnostics declares war on lung cancer

Lung cancer is one of the most common cancers and has a particularly high mortality rate. A significant challenge in treating this disease lies in the resistance of lung tumours to conventional drug therapies, rendering chemotherapy ineffective. There is hope on the horizon as a team of experts from Baden-Württemberg has joined forces to develop an innovative AI-supported test procedure that paves the way for individualised therapy approaches.

Triple-negative breast cancer (TNBC) is the most aggressive and deadly form of breast cancer with limited treatment options. Tumor growth and relapse of TNBC are driven by breast cancer stem cells, and improved therapies that can eliminate those hardy cells are urgently needed. Researchers from the University of Frieburg discovered that coordinated differentiation and changes in the metabolism of breast cancer stem cells make them invisible for…

Researchers at the German Cancer Research Center (DKFZ) have succeeded in identifying a resistance mechanism that often occurs in a specific targeted therapy against chronic lymphocytic leukemia (CLL). The drug ibrutinib is effective in many cases, but therapy resistance often develops during the course of treatment. In cell culture experiments and in mice, the resistance mechanism was successfully overcome using a second drug.

The "livMatS Pavilion" in the Botanical Garden of the University of Freiburg is a model for a bioinspired sustainable construction. In a joint project, researchers from the Universities of Freiburg and Stuttgart together with master’s students from the University of Stuttgart have designed a lightweight pavilion.

Making important raw materials for fine chemicals out of carbon dioxide really works. As part of the Max Planck collaborative project eBioCO2n, a team of researchers from Fraunhofer IGB have successfully performed a first ever fixation of CO2 via a multi-enzyme enzyme reaction driven by electricity yielding a prospective intermediate for the chemical industry. The process for electro-biocatalytic CO2 fixation was recently published and is…

Article - 21/02/2019

Using neuromedical artificial intelligence responsibly

Brain-computer interfaces are the latest developments in the neurotechnology field. They are used to record brain activity, which is then decoded with artificial intelligence techniques and converted into control signals for robots or computers. While this brings hope to severely paralysed people, it also implies risks due to the interest of companies like Google and Facebook in this type of data.

Laboratory studies of lung tissue usually require the removal of large amounts of human or animal tissue. Now scientists from the University of Freiburg’s Faculty of Medicine have succeeded in collaboration with American researchers in generating tiny quantities of lung tissue, so-called organoids, from just a few body cells in the lab.

The Bundesanstalt für Materialforschung und -prüfung (BAM) is developing a more sustainable process to produce active pharmaceutical ingredients in a major EU project: The pilot project is intended to demonstrate the advantages of mechanochemistry for more environmentally friendly and CO2-neutral pharmaceutical production.

PhD student at Furtwangen University develops method for faster determination of antibiotic resistance. The increase in antibiotic-resistant pathogens and the associated treatment, which is a major problem in public healthcare facilities, is the subject of a research project at Furtwangen University.

The European Union is largely dependent on imports of white phosphorus (P4), a strategic raw material for the food and pharmaceutical industries. To tackle this challenge, the newly started four-year EU-funded project FlashPhos – led by the University of Stuttgart – will recover at a large scale high-quality white phosphorus and other raw materials using sewage sludge as input material.

Synergistic effects with microalgae and purple bacteria - 03/02/2023

Working towards a hydrogen economy with a wastewater biorefinery: the SmartBioH2-BW project

A biorefinery that uses industrial wastewater and residual material streams is being built in Rheinfelden (Baden). It will have two interlinking bioreactors and will synthesize biohydrogen as well as organic basic materials such as carotenoids and proteins. SmartBioH2-BW is a pilot project run by the Urban and Industrial Biorefineries initiative and funded by the Baden-Württemberg Ministry of the Environment, Climate Protection and Energy Sector.

At the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, a three-dimensional skin model has now been set up for the first time that directly displays the skin's reaction to substances: The reporter skin. Thanks to the built-in reporter, the cellular response can be measured precisely and quickly – using a living model.

Researchers use epigenetic factors to investigate the role of stress in the development of tumor diseases. Experts believe that stress plays a major role in the development of tumors. One occupational group, for example, that experiences extreme stress over a short period of time is astronauts.