Article - 04/08/2014 A “growing” nail for lengthening bones The lengthening of a bone following a complicated fracture or as a result of the congenital shortening of the leg can help avoid problems that may occur in the future. The use of intramedullary nails to enable the gradual extension of the affected bone has become standard treatment. Prof. Dr.-Ing. Dr. h.c. Paul Gümpel’s group of researchers at the Konstanz University of Applied Sciences (HTWG) has developed an intramedullary nail made of a…https://www.gesundheitsindustrie-bw.de/en/article/news/a-growing-nail-for-lengthening-bones
Article - 04/07/2011 Orthobion GmbH: biomaterials for spinal implants If one takes a closer look at the mechanisms involved in bone growth, it turns out that the supposedly simple issue as to how bones grow cannot be fully answered. Konstanz-based Orthobion GmbH investigates and produces targeted biomaterials for use in implants designed for the treatment of spinal column defects. The surface structures of materials and how they affect the adhesion of bones to implant surfaces are key issues in the production of…https://www.gesundheitsindustrie-bw.de/en/article/news/orthobion-gmbh-biomaterials-for-spinal-implants
Article - 18/07/2011 Titanium screws and stem cells for dental implants How are we supposed to chew and smile when the tooth fairy comes to fetch our second set of teeth? When it’s difficult to tell the difference between modern tooth implants and real teeth in both technical and aesthetical terms, people who lose their teeth due to accidents or age very quickly regain their smile. However, there needs to be enough bone to hold and support the implant. Prof. Dr. Dr. Ralf Gutwald and his team in the Department of Oral…https://www.gesundheitsindustrie-bw.de/en/article/news/titanium-screws-and-stem-cells-for-dental-implants
Article - 15/04/2010 Bone-hard basic research for an ageing society Osteoporotic bones not only break very easily, they also heal badly when a fracture occurs. A fractured femur neck might mean that elderly patients have to remain bedridden for a long period and maybe even need nursing care. Fractures that heal badly, in combination with other diseases, frequently lead to a fatal outcome. A panregional team of researchers, including researchers from Ulm, has been working together since 2007 on basic research into…https://www.gesundheitsindustrie-bw.de/en/article/news/bone-hard-basic-research-for-an-ageing-society
Article - 12/04/2010 A new strategy for improving bone implants Biomechanics is an interdisciplinary field of research and is also of great interest to aerospace engineers. Aerospace engineers at the University of Stuttgart develop equations and models in order to gain a better understanding of the interaction between bones and implants. In addition, they believe that their results will contribute to developing new implants and implant structures.https://www.gesundheitsindustrie-bw.de/en/article/news/a-new-strategy-for-improving-bone-implants
Article - 22/11/2016 Research on the durability and longevity of artificial joints In Germany alone, several hundred thousand patients are given an artificial hip, knee or shoulder joint every year. Prof. Dr. Jan Philippe Kretzer and his team of researchers in the Laboratory of Biomechanics and Implant Research at the University Hospital in Heidelberg are studying what limits the longevity of implants and how durability can be improved. https://www.gesundheitsindustrie-bw.de/en/article/news/research-on-the-durability-and-longevity-of-artificial-joints
Article - 02/07/2008 Virtual biopsy sharpens the view on fragile bones The X-ray-based determination of bone density is currently the only method that enables the early diagnosis of osteoporosis. However this examination method has rather limited informative value. That is why the University Hospital in Tübingen is now establishing high-resolution magnetic resonance imaging MRI that provides the physicians with completely new insights into the microarchitecture of the bones.https://www.gesundheitsindustrie-bw.de/en/article/news/virtual-biopsy-sharpens-the-view-on-fragile-bones
Article - 03/10/2010 Measuring body forces with sensors contained in the implant In collaboration with WITTENSTEIN intens GmbH and Prof. Rainer Baumgart ZEM Munich researchers from the University of Konstanz have further developed the fully implantable telemetrically-controlled distraction nail FITBONE. They have equipped the nail with sensors and energy- and data transmission modules to carry out biomechanical movement and load-bearing analyses of the locomotor system in vivo. The researchers goal is to develop a system to…https://www.gesundheitsindustrie-bw.de/en/article/news/measuring-body-forces-with-sensors-contained-in-the-implant
Press release - 24/08/2008 Enzyme substitutions involving recombinant DNA technology Worldwide less than 10000 people suffer from Gauchers disease which is the most common lysosomal storage disease. Genzyme has been offering the drug Cerezyme for the treatment of this rare genetic disease since 1994. The companys subsidiary in Constance markets and sells this enzyme replacement therapy in Europe and Asia. The active substance is produced in Chinese hamster ovary cell cultures.https://www.gesundheitsindustrie-bw.de/en/article/press-release/enzyme-substitutions-involving-recombinant-dna-technology
Press release - 30/04/2009 Prize for more efficient radiotherapy for leukaemia Peter Kletting’s model can be used to irradiate the tumour cells of leukaemia patients more accurately, reduce potential side effects and increase the chances of therapeutic success. The scientist from the Department of Nuclear Medicine at the University Hospital of Ulm has been awarded the Society for Nuclear Medicine Covidien Award that comes with a purse of 7,500 euros. https://www.gesundheitsindustrie-bw.de/en/article/press-release/prize-for-more-efficient-radiotherapy-for-leukaemia
Article - 19/10/2008 Paradox genders and malformed bones Despite having an X and a Y chromosome carriers of SOX9 gene mutations are nevertheless at risk of developing female sex characteristics. Prof. Dr. Gerd Scherer at the University of Freiburg is investigating how SOX9 controls a persons gender.https://www.gesundheitsindustrie-bw.de/en/article/news/paradox-genders-and-malformed-bones
Article - 14/01/2013 A Heidelberg man of African origin The lower jaw of Homo heidelbergensis was an isolated find and has long been overshadowed by other spectacular early human finds. Homo heidelbergensis is regarded as the last common ancestor of Neanderthals and Homo sapiens, and so is a central part of the debate on modern human origins.https://www.gesundheitsindustrie-bw.de/en/article/news/a-heidelberg-man-of-african-origin
Article - 15/09/2014 Mesenchymal stromal cells: promising cell therapy candidates Mesenchymal stromal cells MSC are increasingly moving into the spotlight as the beacon of hope for somatic cell therapies. The biomedical research community is currently carrying out more than 300 clinical trials to investigate their suitability for a broad range of indications. Prof. Schrezenmeier professor of transfusion medicine and medical director at the Institute for Clinical Transfusion Medicine and Immunogenetics IKT in Ulm is involved in…https://www.gesundheitsindustrie-bw.de/en/article/news/mesenchymal-stromal-cells-promising-cell-therapy-candidates
Article - 29/04/2013 Orthobion – a titanium coated plastic for the spinal column The number of spinal disc herniations and back problems are increasing. In many cases artificial spinal discs need to be implanted to fill the space previously occupied by a removed herniated disc or to help repair another injury. Increasing life expectancy not only requires larger numbers of artificial spinal implants but also increases the demand for improved material properties. In order to overcome the weaknesses of existing implants…https://www.gesundheitsindustrie-bw.de/en/article/news/orthobion-a-titanium-coated-plastic-for-the-spinal-column
Article - 22/06/2015 3D bioprinting: replicating the shape of bone parts Prof. Dr. Günter Finkenzeller, head of the Research and Tissue Engineering Laboratory in the Department of Plastic and Hand Surgery at the Freiburg University Medical Centre, and Dr. Peter Koltay from the Department of Microsystems Engineering (IMTEK) at the University of Freiburg, are being given German Research Foundation (DFG) funds for a period of three years to develop a 3D printing technique for functional bone tissue containing blood…https://www.gesundheitsindustrie-bw.de/en/article/news/3d-bioprinting-replicating-the-shape-of-bone-parts
Article - 30/06/2008 Rays that kill tumour cells Researchers in Ulm are hoping to find new ways to destroy bone marrow cancer multiple myeloma cells through radiation. The German Jos Carreras Leukaemia Foundation is funding the research with a total of about 300000 euros over three years.https://www.gesundheitsindustrie-bw.de/en/article/news/rays-that-kill-tumour-cells
Article - 18/02/2009 Dormant stem cells can be awakened with interferon alpha With a number of new papers published in renowned scientific journals Prof. Dr. Andreas Trumpp has been able to further cement his outstanding reputation as one of the world leaders in stem cell research. Trumpp who has been professor and head of the Department of Cell Biology at the German Cancer Research Centre DKFZ since summer 2008 also became head of the newly founded Heidelberg Institute for Stem Cell Technology and Experimental Medicine…https://www.gesundheitsindustrie-bw.de/en/article/news/dormant-stem-cells-can-be-awakened-with-interferon-alpha
Dossier - 26/03/2012 Nanobiotechnology The term nanotechnology is known by well over 50 of Germans especially since the lotus effect hit the headlines in the late 1990s. Around the turn of the millennium bio was inserted between nano and technology and nanobiotechnology has since taken up more and more room in the headlines as well as requiring major financial investment. What is nanobiotechnology what is the difference between nanotechnology and nanobiotechnology and where and what…https://www.gesundheitsindustrie-bw.de/en/article/dossier/nanobiotechnology
Article - 12/06/2010 Correcting enzyme defects using stem cells Bone marrow transplantation was originally developed for the treatment of leukaemias and other malignant diseases of the haemotopoietic system. Thanks to increasing technological process it has been possible to considerably expand the treatment spectrum over the last few years. Dr. Ingo Müller paediatrician at the University Hospital in Tübingen now uses bone marrow transplantation for the therapy of genetic metabolic diseases with highly…https://www.gesundheitsindustrie-bw.de/en/article/news/correcting-enzyme-defects-using-stem-cells
Article - 25/08/2014 Frederik Wenz - radiologist sets milestone with new surgical technique for the treatment of bone metastases Can painful bone metastases be treated in a targeted and quick way? Can metastases that are potentially present in the liver and kidneys be adequately treated at the same time as bone metastases? These are the questions that Professor Dr. med. Frederik Wenz from the University Medical Center Mannheim asked himself before going on to develop an innovative surgical technique. After a long development period, this technique is now recognized as an…https://www.gesundheitsindustrie-bw.de/en/article/news/frederik-wenz-radiologist-sets-milestone-with-new-surgical-technique-for-the-treatment-of-bone-metas
Press release - 12/03/2009 New strategy for the investigation of haematopoietic stem cells With the newly developed mouse model irradiation is no longer required. While the mutation in the growth factor receptor Kit KitWWv weakens the recipients stem cell compartment and makes room for the incoming donor cells the other two mutations are known to prevent rejection of donor haematopoietic stem cells by the recipients immune system. Thus these mice appear to accept all blood stem cells regardless of the mouse strain origin of the…https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-strategy-for-the-investigation-of-haematopoietic-stem-cells
Dossier - 12/03/2012 Regenerative medicine makes use of patients’ own resources Regenerative medicine offers new therapeutic options for many diseases in which organ function or structure are damaged or lost. The majority of regenerative therapies involve cell-based methods that are often combined with innovative biomaterials. Regenerative therapies combine know-how from the biosciences with state-of-the-art medical technology and also benefit from progress in the engineering and material sciences.https://www.gesundheitsindustrie-bw.de/en/article/dossier/regenerative-medicine-makes-use-of-patients-own-resources
Article - 31/01/2010 A view into the genome provides information on the lipid metabolism Since its foundation around 10 years ago the VIVIT institute in Dornbirn and Feldkirch has been dealing with the impact of disorders of the sugar and lipid metabolisms on the pathogenesis of diseases such as atherosclerosis liver damage or coronary heart disease. https://www.gesundheitsindustrie-bw.de/en/article/news/a-view-into-the-genome-provides-information-on-the-lipid-metabolism
Press release - 24/09/2009 Researchers successfully colonize a textile implant with human stem cells Researchers at the Hohenstein Institute in Stuttgart, Germany developed a method to embed multipotent mesenchymal stem cells onto the surface fibers of common surgical fabric implants. Using such a product it may be possible to directly motivate the regrowth of critical tissue, such as myocardium after a heart attack. https://www.gesundheitsindustrie-bw.de/en/article/press-release/researchers-successfully-colonize-a-textile-implant-with-human-stem-cells
Press release - 16/03/2009 ZKRD: Germans are generous haematopoietic stem cell donors German citizens made as many as 4.166 haematopoietic stem cell donations in 2008. The cells were donated in order to help patients suffering from leukaemia as well as other malignant blood or immune system diseases. “Haematopoietic stem cell donations are often the only chance of a cure for many of these sufferers,” explained Dr. Dr. Carlheinz Müller, Managing Director of the Central German Bone Marrow Donor Registry (ZKRD). https://www.gesundheitsindustrie-bw.de/en/article/press-release/zkrd-germans-are-generous-haematopoietic-stem-cell-donors