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  • Press release - 08/05/2023

    Automated detection of embryonic developmental defects

    Researchers at the University of Konstanz publish image analysis software that automatically detects and classifies defects of animal development. Thanks to artificial intelligence, "EmbryoNet" outperforms human experts in terms of speed, accuracy and sensitivity.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/automated-detection-embryonic-developmental-defects
  • Press release - 24/01/2023

    Genome Editing Procedures Optimised

    Heidelberg scientists succeed in boosting the efficiency of CRISPR/Cas9 and related methods and modifying initially inaccessible DNA sequences.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/verfahren-der-genom-editierung-optimiert
  • Press release - 14/11/2022

    Neurotoxicological hazard assessment without animal testing

    Using animal-free methods to assess the hazard potential of chemicals to the nervous system of unborn children? An international research team including toxicologists from Konstanz and Düsseldorf has developed a testing battery based on human cells that has the potential to replace traditional methods for assessing developmental neurotoxicity.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/neurotoxicological-hazard-assessment-without-animal-testing
  • Press release - 02/11/2022

    How Cells Find the Right Partners

    During the growth and development of living organisms, different types of cells must come into contact with each other in order to form tissues and organs together. A small team working with Prof. Dr. Anne Classen of the Excellence Cluster CIBSS of the University of Freiburg has discovered that complex changes in form, or morphogenesis, during development are driven exclusively via the affinity of cells to each other.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-cells-find-right-partners
  • Gene regulation - 20/07/2021 Vor schwarzem Hintergrund ist ein gelb leuchtendes Chromosom zwischen blau gefärbten Chromosomen sichtbar.

    The many faces of the epigenetic regulator MOF

    Epigenetic modifications play a crucial role in coordinated gene transcription, and are required for a fertilised egg cell to be able to develop into an organism with different cell types. Dr. Asifa Akhtar from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg has been studying the essential epigenetic regulator protein MOF for 20 years.

    https://www.gesundheitsindustrie-bw.de/en/article/news/die-vielen-gesichter-des-epigenetischen-regulators-mof
  • Press release - 27/09/2018

    Three new Clusters of Excellence for Tübingen

    University takes next hurdle in the German government’s Excellence Strategy funding program. The University of Tübingen is to have three new Clusters of Excellence.As part of the German government’s Excellence Strategy funding forhigher education research, Tübingen will host new outstanding research networks starting in January 2019. Representatives of Germany’s higher education policymakers announced the decision in Bonn on Thursday.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/three-new-clusters-of-excellence-for-tuebingen
  • Press release - 27/09/2018

    One hundred percent success

    Two Clusters of Excellence for the University of Freiburg: Biological Signalling Studies and Bioinspired Materials Research. It is a major boost to cutting-edge research in Freiburg: in the current Excellence Strategy competition, scientists at the University of Freiburg have been granted two Clusters of Excellence, CIBSS – Centre for Integrative Biological Signalling Studies, and livMatS – Living, Adaptive and Energy-autonomous Materials…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/one-hundred-percent-success
  • Article - 02/06/2016 B/W photo showing the logo "KIT" against a black background.

    DNA origami for decoding the language of biological cells

    Cells have their own language that they use to communicate with each other. They need this language to be able to form intact tissues and fulfil their specific functions in the body. If these signalling pathways are disrupted, metabolic processes will suffer and result in diseases. We know many “words” of the cellular language, i.e. signalling molecules that bind to specific surface receptors and thereby trigger chemical reactions inside the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/dna-origami-for-decoding-the-language-of-biological-cells
  • Press release - 02/05/2016

    2015 call - ERC Advanced Grants granted to Baden-Württemberg researchers

    The main goal of the European Research Council (ERC) is to fund Europe’s brightest minds and thus encourage the highest quality research. In April 2016, the ERC announced the awarding of its prestigious Advanced Grants, and three life sciences researchers from Baden-Württemberg were among the recipients.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/2015-call-erc-advanced-grants-granted-to-baden-wuerttemberg-researchers
  • Dossier - 18/04/2016 nucleosome_Rippe_DKFZ.jpg

    Epigenetics – heritable traits without changing the DNA sequence

    Epigenetics, i.e. the inheritance of traits that does not involve a change in the DNA sequence, was once a controversial subject that has since become a central focus of biological research. Epigenetic inheritance is now studied by numerous national and international research programmes. Many cellular regulatory and differentiation processes are controlled by epigenetic mechanisms that take place on different levels, including the DNA, histone,…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/epigenetics-heritable-traits-without-changing-the-dna-sequence
  • Article - 17/12/2015 Microscope image showing how stem cells stay close together.

    Inhibition of bromodomain affects stem cell differentiation

    DNA methylation and histone modification are epigenetic mechanisms that affect gene transcription. Moreover, protein complexes can regulate gene expression by modifying chromatin structure and function. Dr. Thomas Günther and his team from the Center for Clinical Research at the Freiburg University Medical Center are studying the effect of the inhibitor PFI-3 on the BAF complex. This protein complex modifies chromatin structure and controls the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/nhibition-of-bromodomain-affects-stem-cell-differentiation
  • Article - 02/12/2015 Schematic representation of the fMEG measurement principle. Left: cross-section through the abdomen of a pregnant woman, showing the foetus; right: measurement unit with the sensors of the fMEG shell. 
The light blue lines running from the belly of the pregnant woman to the right-hand side symbolise the magnetic waves that originate from the foetus and which are recorded.

    Diabetes research: can foetuses develop susceptibility to diabetes in uteri?

    The measurement of blood glucose levels reveals changes in foetal brain response after a pregnant woman has consumed glucose. The postprandial brain response generated by the unborn children of women with gestational diabetes differs from that of children of women without gestational diabetes. Researchers from Tübingen have been using magnetic encephalography to examine the effect of insulin on the brain and the relationships between gestational…

    https://www.gesundheitsindustrie-bw.de/en/article/news/diabetes-research-can-foetuses-develop-susceptibility-to-diabetes-in-uteri
  • Article - 03/09/2015 Coloured photo of Patrick Müller touching a shelf with a fish tank with zebrafish.

    Pattern formation: How undifferentiated cell clusters develop orderly structures

    Dr. Patrick Müller explores cellular signalling pathways that turn undifferentiated cell clusters into orderly structures as embryos develop. Supported by an ERC grant, the Max Planck researcher from Tübingen uses a broad range of methods from the fields of genetics, biophysics, mathematics and the computer sciences for his investigations. Regenerative medicine is one field that particularly stands to benefit from Müller’s findings.

    https://www.gesundheitsindustrie-bw.de/en/article/news/pattern-formation-how-undifferentiated-cell-clusters-develop-orderly-structures
  • Article - 29/06/2015 Neher sitting in front of his computer, pointing at a drawing on the screen.

    How can influenza virus prediction be improved?

    Every February, the World Health Organisation (WHO) publishes recommendations on the composition of influenza virus vaccines for use in the upcoming influenza season. The WHO’s decision is based on observations and laboratory tests as well as experience and intuition. The particular type of influenza virus that is likely to be circulating in a given season has previously been mainly a matter of speculation. Richard Neher from the Max Planck…

    https://www.gesundheitsindustrie-bw.de/en/article/news/how-can-influenza-virus-prediction-be-improved
  • Article - 15/06/2015 Foto von Prof. Dr. Marja Timmermans in einem Maisfeld.

    Marja Timmermans: Humboldt Professor with a penchant for small RNAs

    Molecular biologist Marja Timmermans has found out how plant cells can communicate with each other using mobile ribonucleic acid molecules. The use of small RNAs (sRNA) is a fundamental principle that applies not only to plant cells, but also to animal and human cells. These days, Timmermans' laboratory methods are used around the world. She has recently been awarded Germany’s most highly endowed international research award - the Alexander…

    https://www.gesundheitsindustrie-bw.de/en/article/news/marja-timmermans-humboldt-professor-with-a-penchant-for-small-rnas
  • Article - 08/06/2015 Schematic representation showing how the combination of two fragments (kidney-shaped green and orange, top right and left) makes it possible to design proteins with new functions (bottom, horseshoe-shaped, in this case by binding of an irregularly shaped, grey molecule that is not bound by the original proteins.

    New construction kit for designing new proteins

    Protein building blocks with well-defined properties that can be assembled into new molecules with desired structures and functions are highly sought after in biotechnology and medicine. Birte Höcker, a biologist at the Max Planck Institute for Developmental Biology in Tübingen, is currently working on this in a project she calls “Protein Lego”.

    https://www.gesundheitsindustrie-bw.de/en/article/news/new-construction-kit-for-designing-new-proteins
  • Article - 26/01/2015 Photo showing a laboratory involved in the TTU "Malaria". The photo shows two scientists working at a work bench.

    Pooling efforts against infectious diseases in Germany

    Over 150 scientists at various locations throughout Germany work together as part of the German Centre for Infection Research (DZIF). The centre focuses on the development of new diagnostic, preventive and therapeutic methods for treating infectious diseases. Scientists from the University and University Hospital of Tübingen and the Max Planck Institute for Developmental Biology are also part of the project. The researchers from Tübingen are…

    https://www.gesundheitsindustrie-bw.de/en/article/news/pooling-efforts-against-infectious-diseases-in-germany
  • Article - 15/12/2014 Schematic showing how cardiac muscle cells are prepared, and how cell nuclei and the genetic material are isolated.

    Heart muscle cell 1.0 and 2.0 – two epigenetic programmes in one cell

    All the cells in an organism have to adapt to changing requirements as they develop and grow - including muscle cells in the heart. Crucial to this process are the cells’ growth in size and epigenetic factors that play a role in modulating the expression of various genes. The role of epigenetics in cancer development has been the focus of research for quite some time. The question is, what role do epigenetic factors play in the development of the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/heart-muscle-cell-1-0-and-2-0-two-epigenetic-programmes-in-one-cell
  • Article - 01/12/2014 22507_de.jpg

    Stem cell research for preventing radiation-induced developmental damage

    Although ionizing radiation is known to cause cell damage and genetic modifications, its effects on embryonic development are still poorly understood. This is why Prof. Dr. Suzanne Kadereit from the Albstadt-Sigmaringen University of Applied Sciences is involved in a cooperative project that uses human embryonic stem cells for studying the effects of ionizing radiation on prenatal brain development. She heads up the only university of applied…

    https://www.gesundheitsindustrie-bw.de/en/article/news/stem-cell-research-for-preventing-radiation-induced-developmental-damage
  • Article - 29/09/2014 22098_de.jpg

    Andrei Lupas – fascination for the complex world of proteins

    Prof. Dr. Andrei Lupas is a molecular biologist and director of the Department of Protein Evolution at the Max Planck Institute (MPI) for Developmental Biology in Tübingen. He became fascinated by the incredible complexity of proteins early on during his scientific career. His work focuses on the use of laboratory and computational methods to solve the question as to how a simple amino acid chain becomes a protein ‘nanomachine’. Lupas and his…

    https://www.gesundheitsindustrie-bw.de/en/article/news/andrei-lupas-fascination-for-the-complex-world-of-proteins
  • Article - 31/03/2014 Microscopic image in which the nuclei and cytoskeleton are strained.

    Lsd1 – a gatekeeper for differentiation onset of embryonic mouse stem cells

    Epigenetics is an emerging field of research that studies heritable changes in gene expression that are not caused by changes in the underlying DNA sequence. Prof. Dr. Roland Schüle, Director of Central Clinical Research at the Freiburg University Medical Centre, and his team are specifically focused on epigenetic modifiers that regulate the timely development of placental mouse tissue. Schüle and his team have discovered in mouse embryos that a…

    https://www.gesundheitsindustrie-bw.de/en/article/news/lsd1-a-gatekeeper-for-differentiation-onset-of-embryonic-mouse-stem-cells
  • Article - 17/03/2014 Schematic drawing of Drosophila. The Hox genes, which are critical for the differentiation of the fly’s body segments, are located very close to one another and are expressed in the developing embryo in the order of the segments.

    Hox gene found to influence germline stem cell niche

    Prof. Dr. Ingrid Lohmann and her team at the Centre for Organismal Studies COS at the University of Heidelberg are studying the effect of Hox proteins on the early development of Drosophila using genomic genetic molecular and biochemical methods along with complex computer analyses and simulations. They have cast light on a basic regulatory mechanism of stem cell differentiation. They were able to show that the Hox transcription factor Abd-B is…

    https://www.gesundheitsindustrie-bw.de/en/article/news/hox-gene-found-to-influence-germline-stem-cell-niche
  • Article - 14/10/2013 20380_de.jpg

    ERC Starting Grant for developmental research on microproteins

    Very small proteins play a very important role in the research of Dr. Stephan Wenkel, head of a group of researchers at the Centre for Plant Molecular Biology (ZMBP) in Tübingen. Wenkel has been awarded an ERC Starting Grant, a highly prestigious award given by the European Research Council to up-and-coming research leaders. Wenkel will use the grant to characterise microproteins in order to obtain important insights into the molecular basis of…

    https://www.gesundheitsindustrie-bw.de/en/article/news/erc-starting-grant-for-developmental-research-on-microproteins
  • Article - 23/09/2013 20350_de.jpg

    Giorgos Pyrowolakis to investigate the playground of evolution

    Amazing but true: the basic state of a cell theoretically enables it to develop into any other possible cell. However, certain signalling molecules (morphogens) and the quantity in which they are present cause cells to develop into specific cells. In the fruit fly Drosophila melanogaster, they may become part of the wing, part of a leg or an intestinal cell. Dr. Giorgos Pyrowolakis, a developmental biologist at BIOSS (Centre for Biological…

    https://www.gesundheitsindustrie-bw.de/en/article/news/giorgos-pyrowolakis-to-investigate-the-playground-of-evolution
  • Article - 09/09/2013 The photo shows Dr. Karsten Borgwardt.

    Karsten Borgwardt, a specialist in data mining

    The use of cutting-edge genomics, proteomics and metabolomics methods generates ever-increasing amounts of data in ever decreasing timescales. Special mathematical and computational methods are required for deducing relevant information from specific patterns. The data mining specialist Karsten Borgwardt from Tübingen is developing such methods for specific application in the life sciences.

    https://www.gesundheitsindustrie-bw.de/en/article/news/karsten-borgwardt-a-specialist-in-data-mining
  • Article - 29/07/2013 20147_de.jpg

    Genetic fingerprinting - a useful method in fruit production

    Genetic fingerprinting is a well-known technique used for paternity testing and in forensic science. However, the technique is also used in the field of agriculture. Molecular genetics makes it possible to develop and apply new research and breeding methods to the field of fruit production in order to improve production and quality standards. Dr. Haibo Xuan from the Competence Centre for Fruit Production (KOB) at Lake Constance has been working…

    https://www.gesundheitsindustrie-bw.de/en/article/news/genetic-fingerprinting-a-useful-method-in-fruit-production
  • Article - 10/06/2013 Dr. Tanja Waldmann (right) and her doctoral student Nina Balmer are developing cell culture systems with human embryonic stem cells. The photo shows the two scientists working in the laboratory.

    Stem-cell tests to provide protection to unborn babies

    The development of unborn babies may already be impaired in the womb by pollutants from the environment food and drugs to which their mothers are exposed. Reliable and informative toxicity tests are necessary in order to assess and prevent the effects toxic substances may have on unborn babies. Biologist Dr. Tanja Waldmann from Konstanz University is developing toxicity test systems based on human embryonic stem cells which contribute to improved…

    https://www.gesundheitsindustrie-bw.de/en/article/news/stem-cell-tests-to-provide-protection-to-unborn-babies
  • Article - 08/04/2013 19469_de.jpg

    The first major cell migration

    It is of crucial importance that cells stick tightly together where their function requires them to do so for example in organs such as the heart and the liver to name but two examples. However it is equally crucial that cells start to migrate at some stage during embryonic development in order to form such organs. Prof. Dr. Wolfgang Driever from the Institute of Biology I at the University of Freiburg and his team have elucidated the molecular…

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-first-major-cell-migration
  • Article - 11/03/2013 Microscope image of a root tip with differently coloured cells.

    MicroRNAs – the saviours of stem cells

    Life means almost permanent renewal. Layers of skin and the blood cells of animals are replenished on a life-long basis while plants can even grow whole new leaves flowers and branches. All this is due to stem cells the all-rounders of the cell kingdom. In plants and animals stem cells have the potential to give rise to many types of cells thereby giving plants the ability to grow throughout their life cycle. But how does a cell know that it is a…

    https://www.gesundheitsindustrie-bw.de/en/article/news/micrornas-the-saviours-of-stem-cells
  • Article - 25/02/2013 19274_de.jpg

    Frauke Melchior and the SUMO wrestling match between proteins

    Fifteen years ago, molecular biologist Frauke Melchior discovered a new mechanism of posttranslational protein modification that controls a variety of processes in eukaryotic cells. A small protein called SUMO is covalently bound to target proteins by specific enzymes and cleaved by other enzymes. This discovery has shaped Melchior’s scientific career.

    https://www.gesundheitsindustrie-bw.de/en/article/news/frauke-melchior-and-the-sumo-wrestling-match-between-proteins
  • Article - 18/02/2013 19216_de.jpg

    Dickkopf deficiency improves cognitive performance

    Scientists from the German Cancer Research Center have shown that the Dickkopf gene, which regulates head development during embryogenesis, prevents the regeneration of nerve cells in the mouse hippocampus. This also leads to the loss of learning capacity in advanced age. Animals in advanced adult age whose Dickkopf gene had been silenced showed no age-related decline in cognitive performance.

    https://www.gesundheitsindustrie-bw.de/en/article/news/dickkopf-deficiency-improves-cognitive-performance
  • Article - 17/12/2012 18955_de.jpg

    Stefan Schiller – understanding and copying complex molecule systems

    Dr. Stefan Schiller from the Institute for Macromolecular Chemistry at the University of Freiburg became interested in the diversity of molecular possibilities in nature as a student and is now a specialist in bionic chemistry and synthetic nanobiotechnology. Amongst other things his work involves the construction of complex protein machines that transfer signals protein networks for use in medicine and drug shuttles that enable the targeted…

    https://www.gesundheitsindustrie-bw.de/en/article/news/stefan-schiller-understanding-and-copying-complex-molecule-systems
  • Press release - 04/12/2012 18894_de.jpg

    How different nerve cells develop in the eye

    Neurobiologists from Heidelberg University’s Centre for Organismal Studies (COS) have gained new insights into how different types of nerve cells are formed in the developing animal. Through specialised microscopes, they were able to follow the development of the neural retina in the eye of living zebrafish embryos. Using high-resolution three-dimensional time-lapse images the researchers simultaneously observed the division of retinal nerve…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-different-nerve-cells-develop-in-the-eye
  • Press release - 15/11/2012 18690_de.jpg

    How bacteria attack their host cells with sticky lollipops

    Yersinia enterocolitica, a pathogenic bacterium, causes fever and diarrhea. By help of a protein anchored in its membrane, Yersinia attaches to its host cells and infects them. Scientists of the Max Planck Institute for Developmental Biology in Tübingen and the Leibniz-Institut fuer Molekulare Pharmakologie in Berlin have determined the structure of an important component of the membrane protein and have gained insight into its biogenesis. The…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-bacteria-attack-their-host-cells-with-sticky-lollipops
  • Press release - 12/11/2012 18647_de.jpg

    Phosphate switch to fine-tune the protein production in cells

    MicroRNAs are essential regulators of the genetic program in multicellular organisms. Because of their potent effects the production of these small regulators has itself to be tightly controlled. That is the key finding of a new study performed by Tübingen scientists at the Max Planck Institute for Developmental Biology. They identified a new component that modulates the production of microRNAs in thale cress by the removal of phosphate residues…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/phosphate-switch-to-fine-tune-the-protein-production-in-cells
  • Article - 15/10/2012 18357_de.jpg

    ERC Starting Grants 2012: Baden-Württemberg achieves above-average success

    On September 10th 2012, the European Research Council (ERC) announced the results of the fifth funding round of its Starting Grants. Baden-Württemberg was awarded 13 grants, and is the state with the largest number of a total of 34 grants awarded to German life sciences researchers. Baden-Württemberg life sciences researchers will be receiving Starting Grants worth around 20 million euros.

    https://www.gesundheitsindustrie-bw.de/en/article/news/erc-starting-grants-2012-baden-wuerttemberg-achieves-above-average-success
  • Press release - 20/09/2012 18119_de.jpg

    Discus throw with cancer signals

    The Wnt signaling protein plays an important part in embryonic development and also in the development of diseases such as cancer. It has been unknown until now just how Wnt is carried from cell to cell. Scientists of the German Cancer Research Center and Medical Faculty Mannheim of Heidelberg University have now discovered that the protein is shipped on small discus-shaped vesicles called exosomes. The researchers are now investigating whether…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/discus-throw-with-cancer-signals
  • Article - 18/09/2012 18061_de.jpg

    Michael Kühl: in search of the gene architects of the heart

    Michael Kühl is investigating the development of the heart using a broad range of different model organisms. The developmental biologist, director of the Institute of Biochemistry and Molecular Biology at the University of Ulm, also uses evolutionary and systems biology approaches for his work. Kühl’s basic research does not follow an art for art’s sake principle, but also addresses the development of new therapies for the treatment of heart…

    https://www.gesundheitsindustrie-bw.de/en/article/news/michael-kuehl-in-search-of-the-gene-architects-of-the-heart
  • Press release - 12/09/2012 18102_de.jpg

    Allegedly Useless Parts of the Human Genome Fulfil Regulatory Tasks

    The international ENCODE project aims to assemble an encyclopedia of all functional DNA elements in the human genome. The Heidelberg scientists were able to confirm in a showcase with the model organism Medaka fish that surprisingly many of the analysed elements in the non-protein-coding part of the DNA can actually regulate gene activity in a very specific way.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/allegedly-useless-parts-of-the-human-genome-fulfil-regulatory-tasks
  • Article - 27/08/2012 17960_de.jpg

    Why don't dogs talk?

    Humans have developed a unique ability to communicate through speech and language. Research focusing on the development of human language and its genetic basis focuses specifically on the developmental gene FOXP2. Evo-devo research has shown that a human-specific FOXP2 variant is key for the human ability to talk. It is likely that the human variant of the rather common FOXP2 protein was already present in Neanderthals.

    https://www.gesundheitsindustrie-bw.de/en/article/news/why-don-t-dogs-talk
  • Article - 27/08/2012 17920_de.jpg

    The discovery of homeotic genes

    Research into the genes that cause erroneous developments in fruit flies have led to one of the most exciting discoveries in the field of developmental biology: the same type of gene that controls early embryonic development in Drosophila, also controls early embryogenesis of other organisms, including humans. These homeotic genes are lined up on the DNA in exactly the same order as they are expressed along the body axis during embryogenesis.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-discovery-of-homeotic-genes
  • Article - 27/08/2012 The photo shows a group of eight people standing on a terrace.

    How the distance from the source affects tissue patterning and growth in embryos

    During the embryonic development of fruit flies, zebra fish and humans, just a handful of molecules control cell migration, induce cell division and determine which cells form which type of tissue. A group of researchers led by Dr. Giorgos Pyrowolakis at the University of Freiburg is specifically focused on one of these so-called master regulators. How do the differently patterned BMP gradients develop in Drosophila melanogaster eggs, embryos and…

    https://www.gesundheitsindustrie-bw.de/en/article/news/how-the-distance-from-the-source-affects-tissue-patterning-and-growth-in-embryos
  • Article - 27/08/2012 Group of eight people standing in front of a green hedge.

    Cardiac or intestinal progenitor cells? What controls the fate of pluripotent stem cells?

    Cell fate decisions are made in the early mouse embryo when it is nothing more than a spherical mass of cells. A molecule known as eomesodermin determines whether pluripotent stem cells become cardiac or intestinal progenitor cells. Dr. Sebastian Arnold and his research group at the Freiburg University Medical Centre have recently discovered why one single molecule can have a twofold effect. These findings provide Arnold and his team with greater…

    https://www.gesundheitsindustrie-bw.de/en/article/news/cardiac-or-intestinal-progenitor-cells-what-controls-the-fate-of-pluripotent-stem-cells
  • Article - 27/08/2012 17923_de.jpg

    A worm that turned

    The body plan of vertebrates resembles an earthworm turned on its back. Unsurprisingly, this radical idea initially met with great criticism but modern evo-devo research supports this idea of inversion. An evolutionarily conserved gene cassette determines the dorsoventral axis in the developing embryo. It does so in both vertebrates and invertebrates. However, the body plans of vertebrates and invertebrates are dorsoventrally inverted with…

    https://www.gesundheitsindustrie-bw.de/en/article/news/a-worm-that-turned
  • Dossier - 27/08/2012 17919_de.jpg

    Evo-devo - the synthesis of developmental biology and evolution

    Evo-devo research has led to completely new ideas concerning the evolution of animals, their tissues and organs. The huge variety of animals on the planet is the result of changes in the activity of a limited number of master genes that control early embryonic development. These master genes have been highly conserved throughout evolution, which is why their analysis allows conclusions to be drawn concerning the evolution of multicellular animals…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/evo-devo-the-synthesis-of-developmental-biology-and-evolution
  • Press release - 17/08/2012 17915_de.jpg

    Max Planck scientist investigates the evolutionary model of Muller’s ratchet

    Especially in small asexual populations unfavourable mutations can accumulate. This process is known as Mullers ratchet in evolutionary biology. The ratchet predicts that the genome deteriorates irreversibly leaving populations on a one-way street to extinction. In collaboration with colleagues from the US Richard Neher from the Max Planck Institute for Developmental Biology has shown mathematically how Mullers ratchet operates and he has…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/max-planck-scientist-investigates-the-evolutionary-model-of-muller-s-ratchet
  • Press release - 16/07/2012 17688_de.jpg

    Winners of the "Science2Start" ideas competition honoured

    BioRegio STERN Management GmbH honoured the three winners of the regional "Science2Start" ideas competition last Thursday evening. The award ceremony was part of the traditional summer soirée given by BioRegio STERN Management GmbH in collaboration with TTR Technologieparks Tübingen-Reutlingen GmbH, the Verein zur Förderung der Biotechnologie und der Medizintechnik e.V. (Society for the Promotion of Biotechnology and Medical Technology)…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/winners-of-the-science2start-ideas-competition-honoured
  • Article - 05/06/2012 17261_de.jpg

    Max Planck Director Izaurralde honored for groundbreaking research

    Professor Dr. Elisa Izaurralde has made important contributions to the field of RNA biology in recent years. The managing director of the Max Planck Institute for Developmental Biology in Tübingen explores the complex mechanisms of cellular gene regulation. For her work on mRNA regulation she has now been honored with the prestigious Ernst Jung Prize for Medicine.

    https://www.gesundheitsindustrie-bw.de/en/article/news/max-planck-director-izaurralde-honored-for-groundbreaking-research
  • Press release - 14/03/2012 16661_de.jpg

    How a natural antibiotic found in sweat affects microorganisms

    The skin creates a barrier between the body and its environment. Natural antibiotics that can kill potential pathogens such as bacteria or fungi represent an additional level of protection by the immune system. Dermcidin one such antibiotic produced in human sweat glands is active against a number of microorganisms on the skin. A team of scientists from the University Hospital Tübingen and the Max Planck Institute for Developmental Biology were…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-a-natural-antibiotic-found-in-sweat-affects-microorganisms
  • Article - 13/02/2012 16429_de.jpg

    Almut Köhler – cadherin-mediated cell adhesion and dispersion

    Cadherins ensure that cells within tissues are bound together. However this is only one side of the coin. Dr. Almut Köhler from the Karlsruhe Institute of Technology KIT and her group of researchers are investigating a cadherin type that is even able to actively promote cell migration in developing frog brains and tumour tissue.

    https://www.gesundheitsindustrie-bw.de/en/article/news/almut-koehler-cadherin-mediated-cell-adhesion-and-dispersion

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