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  • Press release - 28/04/2022

    Tumors on withdrawal: Amino acid deficiency shrinks childhood tumors

    Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM* gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/tumors-withdrawal-amino-acid-deficiency-shrinks-childhood-tumors
  • Article - 16/07/2012 17526_de.jpg

    Laupheim to become an international forum for biomanufacturing

    The 2nd Laupheimer Zelltage conference organized by Rentschler Biotechnologie GmbH in Laupheim on 11th and 12th June 2012 focused on “Bioprocess light”. Twelve experts from applied research institutions and biotech companies from Germany and abroad provided the 200 or so guests with information on how modern bioproduction methods can be made simpler, more robust, cheaper, more reliable and hence more competitive.

    https://www.gesundheitsindustrie-bw.de/en/article/news/laupheim-to-become-an-international-forum-for-biomanufacturing
  • Article - 03/06/2013

    With metabolomics food analytics goes all the way

    In the not-too-distant future, food analysts hope they will be able do more than just detect mycotoxin traces and determine the concentration of individual nutrients such as vitamin C. Their ambition is in fact much broader: “We would like to understand the nutritional and physiological effect of food,” said Prof. Sabine Kulling from the Max Rubner Institute in Karlsruhe. As with other life sciences areas, metabolomics is seen as a key technology…

    https://www.gesundheitsindustrie-bw.de/en/article/news/with-metabolomics-food-analytics-goes-all-the-way
  • Article - 21/03/2011 13966_de.jpg

    Andrea Hartwig – trace elements, toxic metals and the thin line in between

    For more than 25 years Prof. Dr. Andrea Hartwig has been investigating the quantities of metal compounds that have a beneficial or toxic effect on human health. As a basic researcher the new chair of the Department of Food Chemistry and Toxicology at the Karlsruhe Institute of Technology KIT has managed to clarify many mechanisms of action of toxic metals including on the molecular level.

    https://www.gesundheitsindustrie-bw.de/en/article/news/andrea-hartwig-trace-elements-toxic-metals-and-the-thin-line-in-between
  • Article - 12/07/2010

    Twelve in one fell swoop – New type 2 diabetes genes

    An international team of scientists working on the largest diabetes study to date have found 12 new diabetes genes in around 140000 Europeans. One of the authors the endocrinologist Bernhard Böhm from Ulm considers the findings to be a breakthrough in the research and treatment of type 2 diabetes.

    https://www.gesundheitsindustrie-bw.de/en/article/news/twelve-in-one-fell-swoop-new-type-2-diabetes-genes
  • Dossier - 06/03/2018 The diagram shows a huge tidal wave with a mighty crest breaking on a person with a bowed head. Along the wave are keywords that reflect the opportunities (optimisation, data management, research, precision medicine) and risks (databases, monitoring) of using big data.

    Big data - the big promise of the new digitised world

    Big data is a widely used buzzword in today's information era. The use of big data in the digital world presents both an opportunity and a risk. Mass data is now used and analysed in almost all areas of life. Even the healthcare sector is undergoing extensive digitisation.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/big-data-the-big-promise-of-the-new-digitised-world
  • Article - 25/07/2011 The photo shows the face of a dark-haired man with glasses.

    Christian Thoma – the control of translation enables the rapid regulation of cellular processes

    Heisenberg fellow PD Dr. Christian Thoma from the Freiburg University Medical Centre has been focusing on the regulation of translation for a number of years and has established a method that enables him to investigate translation on the molecular level. Thoma and his team have come a step closer to their goal of finding targets for the therapy of cancer and hepatitis C.

    https://www.gesundheitsindustrie-bw.de/en/article/news/christian-thoma-the-control-of-translation-enables-the-rapid-regulation-of-cellular-processes
  • Article - 30/08/2010 12096_de.jpg

    Genetic testing for the prevention of diseases?

    Genetic testing is beginning to play an important role in personalised medicine and is indispensable for the diagnosis and therapy of many diseases. However, the preventive and diagnostic power of many genetic tests is still inferior to traditional diagnostic tests. In addition, commercial genetic tests do not always live up to the claims made about them.

    https://www.gesundheitsindustrie-bw.de/en/article/news/genetic-testing-for-the-prevention-of-diseases
  • Dossier - 02/12/2013

    RNA interference: confidence is returning

    The 15-year history of RNA interference is not short on dramatic effects. It begins with the unexpected discovery and publication of the process of post-transcriptional gene silencing in 1998 for which the two Americans Andrew Fire and Craig Mello were awarded the Nobel Prize in Physiology or Medicine just eight years after their discovery. In 2001 Thomas Tuschl succeeded in switching off genes in human cells with small synthetic pieces of RNA…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/rna-interference-confidence-is-returning
  • Article - 23/07/2012 The photo shows a group of eight people in a desert.

    Inhospitable niches are a rich source of extremozymes

    At first sight nothing much seems to grow in either the Namib desert or the Antarctic. However a closer inspection of the ground a few centimetres below the surface reveals an enormous diversity of organisms. Industry is well aware of this rich source of microorganisms that have something to offer on the molecular level as well as for use in technical applications. So-called extremozymes have long been popular ingredients in cosmetics detergents…

    https://www.gesundheitsindustrie-bw.de/en/article/news/inhospitable-niches-are-a-rich-source-of-extremozymes
  • Article - 05/03/2012 16575_de.jpg

    Processing of olfactory cues in the brain

    The question as to how the brain produces useful information from the electrical stimuli coming from the sensory organs is a key issue in the neurosciences. Researchers from Heidelberg are investigating how mice discriminate odours and have shown that complex behaviour emerges from the properties of cells and molecules. Using highly specific genetic manipulations for their experiments, the researchers have been able to show that inhibitory…

    https://www.gesundheitsindustrie-bw.de/en/article/news/processing-of-olfactory-cues-in-the-brain
  • Press release - 01/02/2012 Logo DKFZ, blue letters "DKFZ"

    Defects in the packaging of genetic material in malignant brain tumors

    Glioblastomas are regarded as particularly aggressive brain tumors. In children with glioblastoma, Heidelberg scientists have now discovered genetic alterations that affect the function of DNA packaging proteins known as histones. In a cell, histones serve as coils around which the DNA wraps. At the same time, histones regulate gene activity. Mutations in histone genes have never before been tied to a disease. The group comprising scientists of…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/defects-in-the-packaging-of-genetic-material-in-malignant-brain-tumors
  • Article - 28/02/2008

    Gilbert Gorr - a great fan of the moss Physcomitrella patens

    Dr. Gilbert Gorr has been fascinated by the moss Physcomitrella patens for many years in fact it occupies a great deal of his waking moments. The enthusiasm with which the CSO of greenovation Biotech GmbH talks about the key object of his work is both intoxicating and contagious. The latest discovery The moss produces a therapeutic antibody that is far more effective than its predecessors created in animal cell cultures.

    https://www.gesundheitsindustrie-bw.de/en/article/news/gilbert-gorr-a-great-fan-of-the-moss-physcomitrella-patens
  • Article - 26/08/2009 The photo shows a small fly with red eyes.

    Are fruit flies on the rise again?

    An inconspicuous buzzing insect – it is difficult to imagine that such a creature could be used as a model for humans. Nevertheless, since the beginning of the 20th century Drosophila melanogaster has provided us with decisive insights into human genetics, development and neurobiology. Prof. Dr. Karl-Friedrich Fischbach of the University of Freiburg has been focusing on the development and function of the fruit fly brain for several decades. What…

    https://www.gesundheitsindustrie-bw.de/en/article/news/are-fruit-flies-on-the-rise-again
  • Article - 23/05/2018 Electron microscope image of a bacteriophage.

    Bacteriophages as alternatives to antibiotics

    Multidrug-resistant bacteria are resistant to many existing antibiotics and can be difficult to treat. There are increasing numbers of them worldwide. Although novel antibiotics are being developed, there are far too few of them to tackle the rise of multidrug-resistant bacteria. In Eastern Europe, doctors have been treating bacterial infections with viruses that infect bacteria, so-called bacteriophages, for almost 100 years.

    https://www.gesundheitsindustrie-bw.de/en/article/news/bacteriophages-as-alternatives-to-antibiotics
  • Article - 24/06/2013 19893_de.jpg

    Cloned human beings are not to be feared

    An international team of scientists led by Dr. Shoukhrat Mitalipov at the Oregon Health & Science University, USA, succeeded for the first time ever in cloning human embryonic stem cells by somatic cell nuclear transfer. This breakthrough raises questions about the potentials and dangers of creating human stem cells by cloning. Prof. Dr. Marcel Leist from the University of Konstanz, who uses human embryonic stem cells for his research, gives…

    https://www.gesundheitsindustrie-bw.de/en/article/news/cloned-human-beings-are-not-to-be-feared
  • Article - 30/01/2008 The photo shows Prof. Valentin Wittmann sitting at a desk

    How cells communicate

    Prof. Valentin Wittmann professor in the Department of Chemistry at the University of Constance is investigating carbohydrates. At present his major area of interest is carbohydrate-RNA and carbohydrate-protein interactions where he is trying to understand the biological functions of complex sugar molecules glycans.

    https://www.gesundheitsindustrie-bw.de/en/article/news/how-cells-communicate
  • Article - 07/11/2008

    Living cells in focus

    Prof. Christoph Cremer Cremer hopes to use the Vertico-SMI nanoscope to decipher the molecular secrets of cells. After the 4Pi microscopy this system is the second development of his scientific career to break through the barrier of optical microscopy.

    https://www.gesundheitsindustrie-bw.de/en/article/news/living-cells-in-focus
  • Article - 04/05/2009 Portrait of Dr. Dr. Perikles Simon.

    Perikles Simon – more than just hunting down the dope cheats

    Whether it be the Olympic Games world championships or the Tour de France whenever a big sports event is coming up Dr. Dr. Perikles Simon from the University Hospital of Tübingen is a sought-after interviewee for the media. Simon has developed a test which may eventually help detect the latest performance-enhancing method gene doping.

    https://www.gesundheitsindustrie-bw.de/en/article/news/perikles-simon-more-than-just-hunting-down-the-dope-cheats
  • Vaccine development - 25/05/2021 AdobeStock_385688184_CROCOTHERY.jpg

    Vaccines – a beacon of hope in the fight against pandemics

    Having long been considered less lucrative for the big pharmaceutical companies, vaccine development is taking off in an unforeseen way in the wake of the COVID-19 pandemic. Financial support is flooding in and all kinds of vaccine development strategies are being deployed. Among the winners in the competition for effective coronavirus vaccines are vaccines based on RNA technology. The development of much-needed vaccines against many other…

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/vaccines-beacon-hope-fight-against-pandemics
  • Article - 29/11/2010

    Going through the eye of a needle: Translating research findings into individualised patient treatment

    Anyone attempting to assess the importance of pharmacogenetics for drug safety will inevitably end up considering the ambiguous responses of Radio Eriwan. It is true that genetic tests are theoretically able to predict whether an inactive enzyme affects the metabolism of a drug and whether it is necessary to apply a different drug dose. But how can this knowledge be applied in everyday clinical settings when patients with this inactive enzyme are…

    https://www.gesundheitsindustrie-bw.de/en/article/news/going-through-the-eye-of-a-needle-translating-research-findings-into-individualised-patient-treatmen
  • Article - 27/04/2009 Roland Eils is professor of bioinformatics at the University of Heidelberg and the German Cancer Research Centre. In addition, he is one of the founding directors of the systems biology centre BIOQUANT.

    Roland Eils – a mathematician surrounded by molecular biologists

    Not that long ago the Mathematical Faculty of the University of Heidelberg rejected his doctoral thesis but now Roland Eils is professor at the very same faculty. The mathematician whose doctoral thesis was ahead of its time and his two research groups at the University of Heidelberg and the German Cancer Research Centre DKFZ work in the fields of systems biology and oncology. Eils is also one of three founding directors of the systems biology…

    https://www.gesundheitsindustrie-bw.de/en/article/news/roland-eils-a-mathematician-surrounded-by-molecular-biologists
  • Press release - 23/05/2011 14325_de.jpg

    Systems biology in Baden-Württemberg

    The emerging interdisciplinary field of systems biology is pursuing a completely new approach namely the description of the dynamic interplay of all the components of a biological system using mathematical models with the aim of obtaining a holistic view of the system under consideration. This new approach is expected to lead to new approaches for the treatment of diseases and for the industrial production of enzymes. With its three systems…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/systems-biology-in-baden-wuerttemberg
  • Article - 19/11/2009 Cellzome Logo

    Cellzome - kinase inhibitors for therapy

    Cellzome is a privately-owned biotechnology company which develops new drugs for the treatment of rheumatoid arthritis, multiple sclerosis and chronic inflammatory intestinal diseases at its two company sites in Heidelberg (Germany) and Cambridge (UK).

    https://www.gesundheitsindustrie-bw.de/en/article/news/cellzome-kinase-inhibitors-for-therapy
  • Article - 15/03/2010 10212_de.jpg

    Cornelia Ulrich: Cancer prevention through food and sports

    The appointment of Cornelia Ulrich as professor and head of the Departments of Preventive Oncology at the National Centre for Tumour Diseases and the German Cancer Research Centre shows that Heidelberg is expanding its research priorities in the prevention and early diagnosis of cancer. Ulrichs main focus has been on the folic acid metablism C1 compounds and inflammation.

    https://www.gesundheitsindustrie-bw.de/en/article/news/cornelia-ulrich-cancer-prevention-through-food-and-sports

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