Press release - 28/04/2022 Tumors on withdrawal: Amino acid deficiency shrinks childhood tumors Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM* gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.https://www.gesundheitsindustrie-bw.de/en/article/press-release/tumors-withdrawal-amino-acid-deficiency-shrinks-childhood-tumors
Article - 16/07/2012 Laupheim to become an international forum for biomanufacturing The 2nd Laupheimer Zelltage conference organized by Rentschler Biotechnologie GmbH in Laupheim on 11th and 12th June 2012 focused on “Bioprocess light”. Twelve experts from applied research institutions and biotech companies from Germany and abroad provided the 200 or so guests with information on how modern bioproduction methods can be made simpler, more robust, cheaper, more reliable and hence more competitive.https://www.gesundheitsindustrie-bw.de/en/article/news/laupheim-to-become-an-international-forum-for-biomanufacturing
Article - 03/06/2013 With metabolomics food analytics goes all the way In the not-too-distant future, food analysts hope they will be able do more than just detect mycotoxin traces and determine the concentration of individual nutrients such as vitamin C. Their ambition is in fact much broader: “We would like to understand the nutritional and physiological effect of food,” said Prof. Sabine Kulling from the Max Rubner Institute in Karlsruhe. As with other life sciences areas, metabolomics is seen as a key technology…https://www.gesundheitsindustrie-bw.de/en/article/news/with-metabolomics-food-analytics-goes-all-the-way
Article - 21/03/2011 Andrea Hartwig – trace elements, toxic metals and the thin line in between For more than 25 years Prof. Dr. Andrea Hartwig has been investigating the quantities of metal compounds that have a beneficial or toxic effect on human health. As a basic researcher the new chair of the Department of Food Chemistry and Toxicology at the Karlsruhe Institute of Technology KIT has managed to clarify many mechanisms of action of toxic metals including on the molecular level.https://www.gesundheitsindustrie-bw.de/en/article/news/andrea-hartwig-trace-elements-toxic-metals-and-the-thin-line-in-between
Article - 12/07/2010 Twelve in one fell swoop – New type 2 diabetes genes An international team of scientists working on the largest diabetes study to date have found 12 new diabetes genes in around 140000 Europeans. One of the authors the endocrinologist Bernhard Böhm from Ulm considers the findings to be a breakthrough in the research and treatment of type 2 diabetes. https://www.gesundheitsindustrie-bw.de/en/article/news/twelve-in-one-fell-swoop-new-type-2-diabetes-genes
Dossier - 06/03/2018 Big data - the big promise of the new digitised world Big data is a widely used buzzword in today's information era. The use of big data in the digital world presents both an opportunity and a risk. Mass data is now used and analysed in almost all areas of life. Even the healthcare sector is undergoing extensive digitisation. https://www.gesundheitsindustrie-bw.de/en/article/dossier/big-data-the-big-promise-of-the-new-digitised-world
Article - 25/07/2011 Christian Thoma – the control of translation enables the rapid regulation of cellular processes Heisenberg fellow PD Dr. Christian Thoma from the Freiburg University Medical Centre has been focusing on the regulation of translation for a number of years and has established a method that enables him to investigate translation on the molecular level. Thoma and his team have come a step closer to their goal of finding targets for the therapy of cancer and hepatitis C.https://www.gesundheitsindustrie-bw.de/en/article/news/christian-thoma-the-control-of-translation-enables-the-rapid-regulation-of-cellular-processes
Article - 30/08/2010 Genetic testing for the prevention of diseases? Genetic testing is beginning to play an important role in personalised medicine and is indispensable for the diagnosis and therapy of many diseases. However, the preventive and diagnostic power of many genetic tests is still inferior to traditional diagnostic tests. In addition, commercial genetic tests do not always live up to the claims made about them. https://www.gesundheitsindustrie-bw.de/en/article/news/genetic-testing-for-the-prevention-of-diseases
Dossier - 02/12/2013 RNA interference: confidence is returning The 15-year history of RNA interference is not short on dramatic effects. It begins with the unexpected discovery and publication of the process of post-transcriptional gene silencing in 1998 for which the two Americans Andrew Fire and Craig Mello were awarded the Nobel Prize in Physiology or Medicine just eight years after their discovery. In 2001 Thomas Tuschl succeeded in switching off genes in human cells with small synthetic pieces of RNA…https://www.gesundheitsindustrie-bw.de/en/article/dossier/rna-interference-confidence-is-returning
Article - 23/07/2012 Inhospitable niches are a rich source of extremozymes At first sight nothing much seems to grow in either the Namib desert or the Antarctic. However a closer inspection of the ground a few centimetres below the surface reveals an enormous diversity of organisms. Industry is well aware of this rich source of microorganisms that have something to offer on the molecular level as well as for use in technical applications. So-called extremozymes have long been popular ingredients in cosmetics detergents…https://www.gesundheitsindustrie-bw.de/en/article/news/inhospitable-niches-are-a-rich-source-of-extremozymes
Article - 05/03/2012 Processing of olfactory cues in the brain The question as to how the brain produces useful information from the electrical stimuli coming from the sensory organs is a key issue in the neurosciences. Researchers from Heidelberg are investigating how mice discriminate odours and have shown that complex behaviour emerges from the properties of cells and molecules. Using highly specific genetic manipulations for their experiments, the researchers have been able to show that inhibitory…https://www.gesundheitsindustrie-bw.de/en/article/news/processing-of-olfactory-cues-in-the-brain
Press release - 01/02/2012 Defects in the packaging of genetic material in malignant brain tumors Glioblastomas are regarded as particularly aggressive brain tumors. In children with glioblastoma, Heidelberg scientists have now discovered genetic alterations that affect the function of DNA packaging proteins known as histones. In a cell, histones serve as coils around which the DNA wraps. At the same time, histones regulate gene activity. Mutations in histone genes have never before been tied to a disease. The group comprising scientists of…https://www.gesundheitsindustrie-bw.de/en/article/press-release/defects-in-the-packaging-of-genetic-material-in-malignant-brain-tumors
Article - 28/02/2008 Gilbert Gorr - a great fan of the moss Physcomitrella patens Dr. Gilbert Gorr has been fascinated by the moss Physcomitrella patens for many years in fact it occupies a great deal of his waking moments. The enthusiasm with which the CSO of greenovation Biotech GmbH talks about the key object of his work is both intoxicating and contagious. The latest discovery The moss produces a therapeutic antibody that is far more effective than its predecessors created in animal cell cultures.https://www.gesundheitsindustrie-bw.de/en/article/news/gilbert-gorr-a-great-fan-of-the-moss-physcomitrella-patens
Article - 26/08/2009 Are fruit flies on the rise again? An inconspicuous buzzing insect – it is difficult to imagine that such a creature could be used as a model for humans. Nevertheless, since the beginning of the 20th century Drosophila melanogaster has provided us with decisive insights into human genetics, development and neurobiology. Prof. Dr. Karl-Friedrich Fischbach of the University of Freiburg has been focusing on the development and function of the fruit fly brain for several decades. What…https://www.gesundheitsindustrie-bw.de/en/article/news/are-fruit-flies-on-the-rise-again
Article - 23/05/2018 Bacteriophages as alternatives to antibiotics Multidrug-resistant bacteria are resistant to many existing antibiotics and can be difficult to treat. There are increasing numbers of them worldwide. Although novel antibiotics are being developed, there are far too few of them to tackle the rise of multidrug-resistant bacteria. In Eastern Europe, doctors have been treating bacterial infections with viruses that infect bacteria, so-called bacteriophages, for almost 100 years.https://www.gesundheitsindustrie-bw.de/en/article/news/bacteriophages-as-alternatives-to-antibiotics
Article - 24/06/2013 Cloned human beings are not to be feared An international team of scientists led by Dr. Shoukhrat Mitalipov at the Oregon Health & Science University, USA, succeeded for the first time ever in cloning human embryonic stem cells by somatic cell nuclear transfer. This breakthrough raises questions about the potentials and dangers of creating human stem cells by cloning. Prof. Dr. Marcel Leist from the University of Konstanz, who uses human embryonic stem cells for his research, gives…https://www.gesundheitsindustrie-bw.de/en/article/news/cloned-human-beings-are-not-to-be-feared
Article - 30/01/2008 How cells communicate Prof. Valentin Wittmann professor in the Department of Chemistry at the University of Constance is investigating carbohydrates. At present his major area of interest is carbohydrate-RNA and carbohydrate-protein interactions where he is trying to understand the biological functions of complex sugar molecules glycans.https://www.gesundheitsindustrie-bw.de/en/article/news/how-cells-communicate
Article - 07/11/2008 Living cells in focus Prof. Christoph Cremer Cremer hopes to use the Vertico-SMI nanoscope to decipher the molecular secrets of cells. After the 4Pi microscopy this system is the second development of his scientific career to break through the barrier of optical microscopy.https://www.gesundheitsindustrie-bw.de/en/article/news/living-cells-in-focus
Article - 04/05/2009 Perikles Simon – more than just hunting down the dope cheats Whether it be the Olympic Games world championships or the Tour de France whenever a big sports event is coming up Dr. Dr. Perikles Simon from the University Hospital of Tübingen is a sought-after interviewee for the media. Simon has developed a test which may eventually help detect the latest performance-enhancing method gene doping.https://www.gesundheitsindustrie-bw.de/en/article/news/perikles-simon-more-than-just-hunting-down-the-dope-cheats
Vaccine development - 25/05/2021 Vaccines – a beacon of hope in the fight against pandemics Having long been considered less lucrative for the big pharmaceutical companies, vaccine development is taking off in an unforeseen way in the wake of the COVID-19 pandemic. Financial support is flooding in and all kinds of vaccine development strategies are being deployed. Among the winners in the competition for effective coronavirus vaccines are vaccines based on RNA technology. The development of much-needed vaccines against many other…https://www.gesundheitsindustrie-bw.de/en/article/dossier/vaccines-beacon-hope-fight-against-pandemics
Article - 29/11/2010 Going through the eye of a needle: Translating research findings into individualised patient treatment Anyone attempting to assess the importance of pharmacogenetics for drug safety will inevitably end up considering the ambiguous responses of Radio Eriwan. It is true that genetic tests are theoretically able to predict whether an inactive enzyme affects the metabolism of a drug and whether it is necessary to apply a different drug dose. But how can this knowledge be applied in everyday clinical settings when patients with this inactive enzyme are…https://www.gesundheitsindustrie-bw.de/en/article/news/going-through-the-eye-of-a-needle-translating-research-findings-into-individualised-patient-treatmen
Article - 27/04/2009 Roland Eils – a mathematician surrounded by molecular biologists Not that long ago the Mathematical Faculty of the University of Heidelberg rejected his doctoral thesis but now Roland Eils is professor at the very same faculty. The mathematician whose doctoral thesis was ahead of its time and his two research groups at the University of Heidelberg and the German Cancer Research Centre DKFZ work in the fields of systems biology and oncology. Eils is also one of three founding directors of the systems biology…https://www.gesundheitsindustrie-bw.de/en/article/news/roland-eils-a-mathematician-surrounded-by-molecular-biologists
Press release - 23/05/2011 Systems biology in Baden-Württemberg The emerging interdisciplinary field of systems biology is pursuing a completely new approach namely the description of the dynamic interplay of all the components of a biological system using mathematical models with the aim of obtaining a holistic view of the system under consideration. This new approach is expected to lead to new approaches for the treatment of diseases and for the industrial production of enzymes. With its three systems…https://www.gesundheitsindustrie-bw.de/en/article/press-release/systems-biology-in-baden-wuerttemberg
Article - 19/11/2009 Cellzome - kinase inhibitors for therapy Cellzome is a privately-owned biotechnology company which develops new drugs for the treatment of rheumatoid arthritis, multiple sclerosis and chronic inflammatory intestinal diseases at its two company sites in Heidelberg (Germany) and Cambridge (UK).https://www.gesundheitsindustrie-bw.de/en/article/news/cellzome-kinase-inhibitors-for-therapy
Article - 15/03/2010 Cornelia Ulrich: Cancer prevention through food and sports The appointment of Cornelia Ulrich as professor and head of the Departments of Preventive Oncology at the National Centre for Tumour Diseases and the German Cancer Research Centre shows that Heidelberg is expanding its research priorities in the prevention and early diagnosis of cancer. Ulrichs main focus has been on the folic acid metablism C1 compounds and inflammation.https://www.gesundheitsindustrie-bw.de/en/article/news/cornelia-ulrich-cancer-prevention-through-food-and-sports