Press release - 20/11/2024 New bioengineering approaches for the automated production of complex organoids The reproducible and precise production of complex organoid models to simulate human organ malfunctions is the focus of an interdisciplinary research project at Heidelberg University. A research team from the life and engineering sciences is looking to combine the engineering of molecular systems with machine learning and automated production methods. https://www.gesundheitsindustrie-bw.de/en/article/press-release/neue-ansaetze-des-bio-engineering-fuer-die-automatisierte-herstellung-komplexer-organoide
Press release - 05/11/2024 How biomedical innovation improves preclinical research 3D tumor models, simulations of drug responses or plant stems used for testing heart stents: the 3R-BioMedicUS center at the University of Stuttgart is developing innovative biomedical approaches to improve preclinical studies, to be seen in the new video.https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-biomedical-innovation-improves-preclinical-research
Press release - 05/09/2024 Cohesion at the cellular level: flexible yet stable Research teams from the Universities of Konstanz and Potsdam are analyzing how proteins work together to enable our cells to both stick and move. The marker protein paxillin is at the centre of their interest.https://www.gesundheitsindustrie-bw.de/en/article/press-release/cohesion-cellular-level-flexible-yet-stable
Research association - 24/07/2024 SPI-MP: pioneer in personalised medical technology Every person is unique – even when they are ill. This is why many approaches to personalised medicine have been under development. The Stuttgart Partnership Initiative - Mass Personalization (SPI-MP), which focuses on basic research into fabrication and biomaterial technologies for personalised biomedical systems, is at the heart of such research work. The projects range from artificial knee joint cartilage to state-of-the-art stroke diagnostics.https://www.gesundheitsindustrie-bw.de/en/article/news/spi-mp-pioneer-personalised-medical-technology
Press release - 02/07/2024 Artificial intelligence helps physicians make precise heart diagnoses Researchers from the University of Heidelberg have published a study on more than 60,000 patients in the renowned journal Lancet Digital Health, demonstrating the potential of AI in cardiac medicine.https://www.gesundheitsindustrie-bw.de/en/article/press-release/artificial-intelligence-helps-physicians-make-precise-heart-diagnoses
Gender-specific differences - 18/06/2024 Gender medicine: Why is good healthcare not a matter of course for everyone? Gender medicine is the study of gender-specific health differences. Many diseases manifest themselves differently in men and women and therapies do not always have the same effect depending on the sex of the patient being treated. There is currently not enough data on these differences. Research teams including the one led by Professor Dr. Dr. Sonja Loges from the University Medical Centre Mannheim and the DKFZ are seeking to change this.https://www.gesundheitsindustrie-bw.de/en/article/news/gender-medicine-why-good-healthcare-not-matter-course-everyone
Press release - 07/06/2024 German Research Foundation honors researchers for animal testing alternatives Prof. Dr. Peter Loskill and Dr. Silke Riegger from the 3R Center Tübingen for in-vitro models and animal testing alternatives have been awarded the Ursula M. Händel Animal Welfare Prize 2024. The prize, endowed with 80,000 euros, was awarded to them in Würzburg for the development of organ-on-chip (OoC) systems as an alternative to animal testing.https://www.gesundheitsindustrie-bw.de/en/article/press-release/german-research-foundation-honors-researchers-animal-testing-alternatives
Innovation in emergency medicine - 23/05/2024 CARL pushes back the boundaries of resuscitation therapy Few people survive a cardiac arrest; blood stops flowing to the brain and other vital organs and the resulting lack of oxygen causes extensive damage to the body. In response to this, researchers at the University Medical Centre Freiburg and Resuscitec GmbH have developed CARL, an innovative resuscitation system, which – in addition to the oxygen level – adjusts numerous blood parameters to individual patient requirements. This greatly improves…https://www.gesundheitsindustrie-bw.de/en/article/news/carl-pushes-back-boundaries-resuscitation-therapy
Press release - 17/04/2024 Cell Biology: Molecular Code Stimulates Pioneer Cells to Build Blood Vessels in the Body Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year. A team of KIT researchers has now identified a new cell type in blood vessels responsible for vascular growth. This discovery may allow for novel therapeutic strategies to treat ischemic cardiovascular diseases, i.e. diseases that are caused by reduced or absent blood flow.https://www.gesundheitsindustrie-bw.de/en/article/press-release/zellbiologie-molekularer-code-regt-pionierzellen-zum-aufbau-von-blutgefaessen-im-koerper
Press release - 11/04/2024 How the body switches out of “fight” mode Study in Nature unlocks how cortisone inhibits inflammation Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. A team of researchers from Charité – Universitätsmedizin Berlin, Uniklinikum Erlangen and Ulm University have now explored the molecular mechanism of action in greater detail. https://www.gesundheitsindustrie-bw.de/en/article/press-release/wie-der-kampfmodus-im-koerper-beendet-wird-studie-nature-entschluesselt-wie-kortison-entzuendungen-daempft
Press release - 13/03/2024 Diabetes: New technology opens up improved opportunities for research More than seven million people in Germany suffer from diabetes. At the same time, research into drugs to treat this widespread disease is still difficult. Scientists led by Prof. Dr. Peter Loskill from the NMI Natural and Medical Sciences Institute and the Faculty of Medicine of the Eberhard Karls University of Tübingen have now developed a technique that significantly improves the view at the molecular and cell biological level in the pancreas.https://www.gesundheitsindustrie-bw.de/en/article/press-release/diabetes-new-technology-opens-improved-opportunities-research
Press release - 06/02/2024 New T-FINDER Platform Provides Deep Insights Into T Cell Responses Against Novel Cancer Vaccine BioMed X and the Universitätsmedizin Mannheim announced today the publication of two manuscripts in the field of cancer immunology in the journal Science Advances. The work is based on a collaboration bet- ween both institutions and researchers at the German Cancer Research Center (DKFZ), the Heidelberg Uni- versity, and the Helmholtz Institute for Translational Oncology (HI-TRON).https://www.gesundheitsindustrie-bw.de/en/article/press-release/neue-t-finder-plattform-liefert-tiefe-einblicke-t-zell-antwort-auf-neuartigen-krebsimpfstoff
Press release - 04/01/2024 Key player in viral heart inflammation discovered Inflammation of the heart muscle, also known as myocarditis, is a serious consequence of a viral infection. This can impede the heart’s ability to pump blood in the long term. In a current study, researchers of the Faculty of Medicine of the University of Freiburg have discovered a new approach for treating myocarditis. https://www.gesundheitsindustrie-bw.de/en/article/press-release/key-player-viral-heart-inflammation-discovered
Press release - 18/10/2023 SARS-CoV-2: Alert immune system in the respiratory tract protects children from severe courses of the disease Why are severe courses of SARS-CoV-2 infection less common in children and adolescents than in adults? Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now discovered that the immune system in the upper respiratory tract is much more alert and active in children before infection than in adults and is therefore better equipped to fight the virus.https://www.gesundheitsindustrie-bw.de/en/article/press-release/sars-cov-2-aktiveres-immunsystem-den-atemwegen-schuetzt-kinder-vor-schweren-verlaeufen
Press release - 02/10/2023 Distributed artificial intelligence to improve patient care in the operating room A research team of scientists from the Fraunhofer IPA, the Bosch Digital Innovation Hub at Bosch Health Campus and the Institute of Image-Guided Surgery (IHU) of Strasbourg has jointly launched the DAIOR project. Within the framework of the project, the project partners are working on realizing the operating room of the future with help of artificial intelligence and robot assisted telemedicine. https://www.gesundheitsindustrie-bw.de/en/article/press-release/distributed-artificial-intelligence-improve-patient-care-operating-room
Press release - 18/07/2023 National Research Center for cutting-edge AI research in Tübingen celebrates inception On Tuesday, July 18, 2023, the Tübingen AI Center held a symposium to celebrate its permanent establishment as a national AI center. Since July 1, 2022, it has received 20 million euros a year in funding from the federal government and the state. https://www.gesundheitsindustrie-bw.de/en/article/press-release/nationales-forschungszentrum-fuer-ki-spitzenforschung-tuebingen-feiert-seine-gruendung
Reduced immunosuppression possible in transplantations - 05/06/2023 Modified immune cells produce donor-specific tolerance Traditionally, transplant recipients have had to take immunosuppressive medication for life to prevent organ rejection. However, there are considerable side effects involved. Using modified immune cells (MICs), TolerogenixX GmbH from Heidelberg has now managed to generate donor-specific tolerance in recipients of living kidney transplants without suppressing the overall immune system.https://www.gesundheitsindustrie-bw.de/en/article/news/modified-immune-cells-produce-donor-specific-tolerance
Press release - 24/01/2023 Genome Editing Procedures Optimised Heidelberg scientists succeed in boosting the efficiency of CRISPR/Cas9 and related methods and modifying initially inaccessible DNA sequences.https://www.gesundheitsindustrie-bw.de/en/article/press-release/verfahren-der-genom-editierung-optimiert
Press release - 12/01/2023 “Zone of uncertainty” in the brain influences its ability to form new memories Researchers at the University of Freiburg Medical School led by Prof. Dr. Johannes Letzkus and the Max Planck Institute for Brain Research have discovered that a little-studied area of the brain, the "zone of uncertainty" or "zona incerta," communicates with the neocortex in unconventional ways to rapidly control memory formation.https://www.gesundheitsindustrie-bw.de/en/article/press-release/zone-der-ungewissheit-im-gehirn-beeinflusst-bildung-von-erinnerungen
Start-up Actimi GmbH - 23/11/2022 Real-time telemonitoring of heart failure Improved quality of life for patients and lower costs for health insurers: these are the advantages of telemonitoring patients with advanced heart failure. The Stuttgart-based start-up Actimi offers an all-in-one platform for those who treat and those who suffer from the disease.https://www.gesundheitsindustrie-bw.de/en/article/news/real-time-telemonitoring-heart-failure
Press release - 18/08/2022 When smooth muscle cells lack strength University of Tübingen team discovers how malformations of the blood vessels can occur in mice – yielding information with possible ramifications for retinal disease.https://www.gesundheitsindustrie-bw.de/en/article/press-release/when-smooth-muscle-cells-lack-strength
AaviGen GmbH: Hope for heart failure - 14/07/2022 Gene therapy for weakened hearts Treating a weak heart – for example after a heart attack – at the GP’s surgery with a single intravenous injection, without causing serious side effects: what sounds almost too good to be true is actually already under development. The Heidelberg-based biotech company AaviGen is working on a platform technology based on adeno-associated viruses that can help introduce therapeutic genes in a highly specific way into diseased heart muscle cells.https://www.gesundheitsindustrie-bw.de/en/article/news/gene-therapy-weakened-hearts
microRNA as a prognostic biomarker - 13/01/2022 Heart attack diagnosis: fast and unambiguous thanks to artificial intelligence People that arrive in emergency rooms with chest pain require swift action in order to rule out a heart attack or to initiate vital life-saving therapy. However, despite many advances, current tests are not yet optimal: they either take hours or produce false-positive results. Researchers at Heidelberg University Hospital are now using AI in an approach that takes microRNAs from a blood sample to specifically diagnose ‘acute coronary syndrome’.https://www.gesundheitsindustrie-bw.de/en/article/news/heart-attack-diagnosis-fast-and-unambiguous-thanks-artificial-intelligence
Gene regulation - 20/07/2021 The many faces of the epigenetic regulator MOF Epigenetic modifications play a crucial role in coordinated gene transcription, and are required for a fertilised egg cell to be able to develop into an organism with different cell types. Dr. Asifa Akhtar from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg has been studying the essential epigenetic regulator protein MOF for 20 years.https://www.gesundheitsindustrie-bw.de/en/article/news/die-vielen-gesichter-des-epigenetischen-regulators-mof
Article - 08/07/2021 Individual operation risk assessment by the Cognitive Medical Assistant Despite modern surgical techniques and anaesthetic procedures, serious complications can occur during surgical interventions. An interdisciplinary team at Heidelberg University Hospital has launched a project called the Cognitive Medical Assistant (German: Der Kognitive Medizinische Assistant, KoMed for short), designed to better assess the individual risk of these interventions. The project’s goal is to systematically and comprehensively analyse…https://www.gesundheitsindustrie-bw.de/en/article/news/individual-operation-risk-assessment-cognitive-medical-assistant