Epifadin from the nasal microbiome - 28/03/2024 From the nose: novel antibiotic substance discovered Antibiotics are becoming an increasingly blunt weapon against infectious diseases. The number of (multi-)resistant germs has been rising rapidly for years and even reserve antibiotics no longer work. Researchers at the University of Tübingen have now isolated a completely new antibiotic substance called epifadin from the microbiome of the human nose. It is effective against many different bacteria - including the dangerous hospital MRSA.https://www.gesundheitsindustrie-bw.de/en/article/news/nose-novel-antibiotic-substance-discovered
Press release - 18/12/2023 Researchers discover novel antibiotic substance from the human nose For the first time, the active substance epifadin has been isolated at the University of Tübingen – Epifadin is produced by specific bacteria in the nose and on the skin of humans, has an antibiotic effect, and is the first example of a previously unknown antimicrobial compound class.https://www.gesundheitsindustrie-bw.de/en/article/press-release/researchers-discover-novel-antibiotic-substance-human-nose
Recent research shows effectiveness of biosurfactants - 28/11/2023 Combating oil spills - biosurfactants can stimulate microbial oil degradation Oil spills from drilling platforms and tankers cause environmental pollution and a loss of biodiversity. Researchers at the University of Stuttgart, among others, are now using biosurfactants to improve the management of oil spills: their latest research shows that biosurfactants lead to better microbiological degradation of oil components in seawater compared to conventional dispersants.https://www.biooekonomie-bw.de/en/articles/news/combating-oil-spills-biosurfactants-can-stimulate-microbial-oil-degradation
Press release - 25/10/2023 Epigenetically acting drugs could support cancer immunotherapy Epigenetically active drugs enable the cell to read parts of the genome that were previously blocked and inaccessible. This leads to the formation of new mRNA transcripts and also new proteins, as scientists from the German Cancer Research Center and the University Hospital Tübingen have now published. These "therapy-induced epitopes" could help the immune system recognize cancer cells.https://www.gesundheitsindustrie-bw.de/en/article/press-release/epigenetically-acting-drugs-could-support-cancer-immunotherapy
Press release - 20/10/2023 Why tuberculosis bacteria form long chains A researcher team from Ecole Polytechnique Federal de Lausanne led by Dr. Vivek Thacker now group leader at the Department of Infectious Diseases at Heidelberg University Hospital have studied why tuberculosis bacteria form long strands and how this affects their infectivity. Their findings could lead to new therapies and have now been published in the journal Cell.https://www.gesundheitsindustrie-bw.de/en/article/press-release/why-tuberculosis-bacteria-form-long-chains
Microorganisms degrade biobased turf infill - 17/10/2023 Eco-friendly artificial turf: a sports pitch that’s good for people and the environment There are thousands of artificial turf pitches in Germany. They are extremely practical, but often not at all environmentally friendly. When it rains or the pitch is used, plastic particles from the rubber granules can be released into the envronment, where they remain. Researchers at the University of Stuttgart along with the company TECNARO are now developing an artificial turf with an infill that biodegrades as soon as it leaves the pitch.https://www.biooekonomie-bw.de/en/articles/news/eco-friendly-artificial-turf-sports-pitch-s-good-people-and-environment
Press release - 27/07/2023 Self-healing plastic becomes biodegradable Konstanz chemists develop mineral plastics with numerous positive properties from sustainable basic building blocks and, together with biologists, demonstrate the material's excellent microbiological degradability.https://www.biooekonomie-bw.de/en/articles/pm/Self-healing-plastic-becomes-biodegradable
Press release - 21/07/2023 Biosurfactants might offer an environmentally friendly solution for tackling oil spills Can biosurfactants increase microbiological oil degradation in North Sea seawater? An international research team from the universities of Stuttgart und Tübingen, together with the China West Normal University and the University of Georgia, have been exploring this question and the results have revealed the potential for a more effective and environmentally friendly oil spill response.https://www.biooekonomie-bw.de/en/articles/pm/biosurfactants-might-offer-environmentally-friendly-solution-tackling-oil-spills
Press release - 20/06/2023 Tuberculosis Therapy: Smallest Particles Will Deliver the Drug to the Lungs in Future KIT and Research Center Borstel Present Nanoparticles with a High Antibiotic Concentration for Inhalation – Nanocarriers of Antibiotics Can Reduce Resistances and Enhance Compatibility.https://www.gesundheitsindustrie-bw.de/en/article/press-release/tuberculosis-therapy-smallest-particles-will-deliver-drug-lungs-future
Residual materials with potential - 16/03/2023 PeePower™ – energy from urine The objective of the PeePower™ BUGA 2023 collaborative research project is to produce green hydrogen and platform chemicals from wastewater. This fits in nicely with BUGA 2023’s (German National Garden Show) four major themes, namely, climate, energy, environment and food security.https://www.biooekonomie-bw.de/en/articles/pm/peepower-energy-urine
Vaccination for plants - 23/01/2023 Dialogue instead of a chemical maze – new strategy for sustainable crop protection Climate change creates stress. This provides an opportunity for pests to exploit plant weaknesses and reproduce. For the infested plant, this can be catastrophic and often fatal. But instead of continuing to protect harvest yields with toxic substances as before, the transnational DialogProTec project is now taking a completely new approach: researchers want to intervene in the communication between plants and pests to keep them healthy.https://www.biooekonomie-bw.de/en/articles/news/dialogue-instead-chemical-maze-new-strategy-sustainable-crop-protection
Valorization of biological materials - 12/01/2023 ValBio-Urban brings bioeconomy research to users Reducing carbon dioxide emissions and the capture and utilization of CO2 are important steps towards achieving a climate-neutral and sustainable economy. Accordingly, as part of the ValBio-Urban research project, an interdisciplinary team from the University of Stuttgart is developing bioeconomic approaches to solutions that will be implemented with companies from Baden-Württemberg.https://www.biooekonomie-bw.de/en/articles/news/valbio-urban-brings-bioeconomy-research-users
Project FuTuReS - 12/12/2022 Microalgae - high-quality products for domestic agriculture? Algae are aquatic organisms that flourish in a huge variety of species. But that's not all: they are also small green mini-factories that can produce all kinds of valuable materials. All they need is water, light, CO2 and a few nutrients that can be recycled from biogas or sewage treatment plants. Researchers have now determined the optimal framework conditions and practicability of process methods for agricultural algae cultivation.https://www.biooekonomie-bw.de/en/articles/news/microalgae-high-quality-products-domestic-agriculture
Press release - 08/12/2022 Tübingen Environmental Researcher Lars Angenent Receives the Leibniz Prize Tübingen biotechnologist Lars Angenent is being awarded the Leibniz Prize by the German Research Foundation (DFG) in appreciation of his outstanding work in the field of environmental biotechnology, it was announced in Bonn on Thursday. The DFG said: “In view of climate change and the resulting need to develop a sustainable food, chemistry and energy economy, his work is highly relevant.”https://www.bio-pro.de/en/activities/biological-transformation/aktuelles/tuebingen-environmental-researcher-lars-angenent-receives-leibniz-prize
Press release - 08/12/2022 Tübingen Environmental Researcher Lars Angenent Receives the Leibniz Prize Tübingen biotechnologist Lars Angenent is being awarded the Leibniz Prize by the German Research Foundation (DFG) in appreciation of his outstanding work in the field of environmental biotechnology, it was announced in Bonn on Thursday. The DFG said: “In view of climate change and the resulting need to develop a sustainable food, chemistry and energy economy, his work is highly relevant.”https://www.biooekonomie-bw.de/en/articles/pm/tuebingen-environmental-researcher-lars-angenent-receives-leibniz-prize
Press release - 15/11/2022 Silicone Sponge Captures Unknown Bacteria From human intestines to the bottom of the sea: Microorganisms populate nearly any habitat, no matter how hostile it is. Their great variety of survival strategies is of huge potential in biotechnology. Most of these organisms, however, are unknown, because they cannot be cultivated.https://www.gesundheitsindustrie-bw.de/en/article/press-release/silikonschwamm-spuert-unbekannte-bakterien-auf
Press release - 10/10/2022 For Animal Welfare & Environmental Protection: State lays cornerstone for new "HoLMiR" research center More animal welfare and better animal health, more climate protection and less environmental impact: Researchers at the University of Hohenheim in Stuttgart are pursuing these goals with a new approach: They are exploring the interplay between farm animals and the millions of microorganisms in the animals’ digestive tracts. The federal and state governments are supporting the university with the construction of a unique research center for around…https://www.biooekonomie-bw.de/en/articles/pm/fuer-tierwohl-umweltschutz-land-legt-grundstein-fuer-neuartiges-forschungszentrum-holmir
Mini-factories for producing bioplastics - 05/05/2022 Bacteria produce bioplastics: resource-saving and very environmentally friendly Using living cells as mini-factories to produce plastic from nothing more than water, sunlight and carbon dioxide; plastic that is also 100 percent degradable – it sounds far-fetched but it actually works: researchers at the University of Tübingen have genetically engineered cyanobacteria so that they fill their cells to the brim with polyhydroxybutyrate. The researchers are now turning the idea into reality with the development of pilot plants.https://www.biooekonomie-bw.de/en/articles/news/bacteria-produce-bioplastics-resource-saving-and-very-environmentally-friendly
pre-start-up company Wheyfinery - 13/04/2022 Acid whey as a valuable raw material for platform chemicals and more There is not much you can do with acid whey, which is why several million litres of it are disposed of every year. This is both costly and not sustainable. However, researchers at Tübingen University have shown: acid whey can be used to produce precursors for biofuels, fine chemicals and antimicrobial livestock feed additives. They have set up the pre-start-up company Wheyfinery in an endeavour to make their scalable biorefinery concept…https://www.biooekonomie-bw.de/en/articles/news/acid-whey-valuable-raw-material-platform-chemicals-and-more
Press release - 13/01/2022 Turning harmful CO2 into useful chemicals Making important raw materials for fine chemicals out of carbon dioxide really works. As part of the Max Planck collaborative project eBioCO2n, a team of researchers from Fraunhofer IGB have successfully performed a first ever fixation of CO2 via a multi-enzyme enzyme reaction driven by electricity yielding a prospective intermediate for the chemical industry. The process for electro-biocatalytic CO2 fixation was recently published and is…https://www.biooekonomie-bw.de/en/articles/pm/turning-harmful-co2-useful-chemicals
Press release - 30/11/2021 A mould dominates the eukaryotic microbiota in Parkinson’s disease patients Parkinson's disease is characterised by a slow, progressive loss of nerve cells in certain brain areas. The disease is still incurable and the exact causes are unclear. The dopamine deficiency in the brain can only be controlled to some extent in the initial phase of the disease. Basic research is being conducted in an attempt to unravel the mystery of Parkinson's disease.https://www.gesundheitsindustrie-bw.de/en/article/press-release/mould-dominates-eukaryotic-microbiota-parkinsons-disease-patients
Press release - 19/11/2021 Keep an eye on us! – Bacteria on slit lamps Furtwangen University publishes the world’s first molecular biological study on bacterial contamination of slit lamps. Slit lamps are among the most important tools used by ophthalmologists and opticians. They allow selected areas of the eye to be magnified and examined for diseases.https://www.gesundheitsindustrie-bw.de/en/article/press-release/keep-eye-us-bacteria-slit-lamps
Booster for neutrophil granulocytes - 27/10/2021 Acetate supports immune cells to fight against sepsis Blood poisoning is the most dangerous complication of bacterial infections and often leads to death. Researchers at the Interfaculty Institute of Microbiology and Infection Medicine at the University of Tübingen have now identified acetate as a potent agent for stimulating innate immune system cells, supporting their ability to destroy bacteria.https://www.gesundheitsindustrie-bw.de/en/article/news/acetate-supports-immune-cells-fight-against-sepsis
Optimised peptides against infections and cancer - 07/10/2021 New bioactive ingredients from the peptidome treasure chest Peptides are increasingly coming into scientific focus for application in diagnostics and therapy. The human body is full of these protein fragments, but only a fraction have been characterised. So there is enormous potential for discovering new biologically active substances that can help in the fight against bacteria, viruses and cancer. A collaborative research centre at Ulm University Hospital is on the trail of these promising fragments.https://www.gesundheitsindustrie-bw.de/en/article/news/new-bioactive-ingredients-peptidome-treasure-chest
Press release - 27/09/2021 Bacteria can boost the fitness of their host Microorganisms can increase their host’s ability to adapt to the environment and reproduce – evolutionary biologists are now studying the underlying molecular mechanisms. A research team headed by Dr. Fabian Staubach and Yun Wang from the Institute of Biology I at the University of Freiburg has now studied the relationship of Gluconobacter bacteria and fruit flies. They have found that specific Gluconobacter variants supply the flies with vitamin…https://www.gesundheitsindustrie-bw.de/en/article/press-release/bacteria-can-boost-fitness-their-host