Article - 04/03/2013 TellTargeting Medical GmbH – targeted chemotherapy using CARL® The needs of cancer patients are clear chemotherapies that are as gentle as possible associated with minimal adverse effects and have a rapid effect. This is often difficult to achieve because the drug that stops tumour growth needs to remain in the body for a certain amount of time during which time it damages cancerous as well as healthy structures. Dr. Gerhard Pütz and Dr. Jürgen Eckes founded the company TellTargeting Medical GmbH Co. KG…https:////www.gesundheitsindustrie-bw.de/en/article/news/telltargeting-medical-gmbh-targeted-chemotherapy-using-carl
Article - 18/12/2012 Gene therapy medicinal products: the first gene therapy product has been approved – where does the future lie? Is gene therapy close to broad clinical application? Following negative headlines at the end of the 1990s gene therapy had almost disappeared from the public radar to become an issue almost exclusively dealt with by research laboratories. Gene therapy has now reappeared in the public domain since the European Medicines Agency EMA gave the Dutch biotech company uniQure the go-ahead for the application of somatic gene therapy for the treatment of a…https:////www.gesundheitsindustrie-bw.de/en/article/news/gene-therapy-medicinal-products-the-first-gene-therapy-product-has-been-approved-where-does-the-futu
Article - 03/12/2012 DFG strengthens Ulm research into ageing with new research training group The German Research Foundation (DFG) has recently granted Ulm University funding for a research training group (RTG) into ”Cellular and Molecular Mechanisms of Ageing”. This again confirms the strength of ageing research at Ulm University. The granting of funds totalling three million euros over a period of four and a half years is an important indication of the continued strength of the small university, particularly as many were worried that…https:////www.gesundheitsindustrie-bw.de/en/article/news/dfg-strengthens-ulm-research-into-ageing-with-new-research-training-group
Article - 03/12/2012 Differences between white, brown and “brite” fat tissue The latest results on the different metabolic pathways used by white and brown fat cells and potential transformations between the two cell types were discussed at the conference “Metabolism 2012: From Signalling to Disease” held on 15th and 16th November 2012 in Heidelberg. A special cell type, so-called “brite” adipocytes, may have the potential to be used in the treatment of obesity and related metabolic diseases such as diabetes.https:////www.gesundheitsindustrie-bw.de/en/article/news/differences-between-white-brown-and-brite-fat-tissue
Article - 18/09/2012 Michael Kühl: in search of the gene architects of the heart Michael Kühl is investigating the development of the heart using a broad range of different model organisms. The developmental biologist, director of the Institute of Biochemistry and Molecular Biology at the University of Ulm, also uses evolutionary and systems biology approaches for his work. Kühl’s basic research does not follow an art for art’s sake principle, but also addresses the development of new therapies for the treatment of heart…https:////www.gesundheitsindustrie-bw.de/en/article/news/michael-kuehl-in-search-of-the-gene-architects-of-the-heart
Article - 27/08/2012 Cardiac or intestinal progenitor cells? What controls the fate of pluripotent stem cells? Cell fate decisions are made in the early mouse embryo when it is nothing more than a spherical mass of cells. A molecule known as eomesodermin determines whether pluripotent stem cells become cardiac or intestinal progenitor cells. Dr. Sebastian Arnold and his research group at the Freiburg University Medical Centre have recently discovered why one single molecule can have a twofold effect. These findings provide Arnold and his team with greater…https:////www.gesundheitsindustrie-bw.de/en/article/news/cardiac-or-intestinal-progenitor-cells-what-controls-the-fate-of-pluripotent-stem-cells
Article - 25/06/2012 The physiological importance of the Alzheimer protein While the role of the amyloid precursor protein (APP) in the development of amyloid plaques that are characteristic of Alzheimer’s disease is well known, the physiological role of this protein in the brain has remained elusive. However, the molecular biologist Professor Dr. Ulrike Müller from Heidelberg has now shown in mouse models that components of the APP gene family play a major role in synaptic plasticity, learning and memory. https:////www.gesundheitsindustrie-bw.de/en/article/news/the-physiological-importance-of-the-alzheimer-protein
Article - 21/05/2012 Microchip facilitates bowel movements Faecal incontinence is a common problem, but is still a strong taboo. A small microchip, implanted above the sacral bone, promises to make sufferers’ lives a lot easier. Sacral nerve stimulation (SNS) not only restores patients’ ability to control defaecation, but also provides new insights into the innervation and physiology of the bowel and the pelvic floor.https:////www.gesundheitsindustrie-bw.de/en/article/news/microchip-facilitates-bowel-movements
Article - 19/03/2012 Calcium channels – about channel proteins and why we forget things The controlled transport of calcium across cell membranes is crucial for many biological processes including the transfer of information into the brain kidney function and the rhythmic activity of the heart muscle. A team led by Prof. Dr. Norbert Klugbauer at the University of Freiburg is focused on elucidating the function of calcium channels the proteins that regulate them and the effects on learning and memory. The researchers are…https:////www.gesundheitsindustrie-bw.de/en/article/news/calcium-channels-about-channel-proteins-and-why-we-forget-things
Article - 19/03/2012 When the “second brain” fails – therapeutic options from the field of regenerative medicine Researchers from the Center for Regenerative Biology and Medicine ZRM in Tübingen are focused on the enteric nervous system of the gastrointestinal tract with the aim of developing cell-based therapies for the treatment of bowel diseases. The researchers are working with local partners in a BMBF-funded project that is seeking to develop therapies for Hirschsprung’s disease.https:////www.gesundheitsindustrie-bw.de/en/article/news/when-the-second-brain-fails-therapeutic-options-from-the-field-of-regenerative-medicine
Article - 12/03/2012 Q-bios provides client-specific biotechnology services Q-bios GmbH, a spin-off from the Mannheim University of Applied Sciences, is a biotechnology company that provides services related to the production and purification of diagnostic and therapeutic proteins as well as the development and amplification of suitable cell lines. The company offers its services, which are based on state-of-the-art technologies, to clients from the biotechnology, diagnostic and pharmaceutical industries.https:////www.gesundheitsindustrie-bw.de/en/article/news/q-bios-provides-client-specific-biotechnology-services
Dossier - 12/03/2012 Regenerative medicine makes use of patients’ own resources Regenerative medicine offers new therapeutic options for many diseases in which organ function or structure are damaged or lost. The majority of regenerative therapies involve cell-based methods that are often combined with innovative biomaterials. Regenerative therapies combine know-how from the biosciences with state-of-the-art medical technology and also benefit from progress in the engineering and material sciences.https:////www.gesundheitsindustrie-bw.de/en/article/dossier/regenerative-medicine-makes-use-of-patients-own-resources
Article - 19/12/2011 Wolfgang Rottbauer discovers zebrafish for use in cardiology Zebrafish is a popular model organism for many researchers around the world. Life scientists such as evolutionary biologists, neurobiologists and toxicologists frequently use the small vertebrate for their investigations. Wolfgang Rottbauer has discovered and established the zebrafish as a model organism for cardiovascular disease research. He has also made a name for himself in this field. However, Rottbauer recalls that his efforts were…https:////www.gesundheitsindustrie-bw.de/en/article/news/wolfgang-rottbauer-discovers-zebrafish-for-use-in-cardiology
Press release - 07/12/2011 Oxidative stress: Less harmful than suspected? Oxidative stress is considered to be involved in a multitude of pathogenic processes and is also implicated in the proces of aging. For the first time, scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have been able to directly observe oxidative changes in a living organism. Their findings in fruit flies raise doubts about the validity of some widely held hypotheses: The research team has found no evidence…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/oxidative-stress-less-harmful-than-suspected
Article - 26/10/2011 Simple nerve cells regulate swimming depth of marine plankton Scientists of the Max Planck Institute for Developmental Biology in Tübingen Germany have identified some signaling substances in the nervous system of larvae of the marine annelid Platynereis regulating the swimming depth. These substances influence the ciliary beating and thus hold the larvae in the preferred water depth. The scientists discovered a very simple circuitry of nerve cells underlying this regulation reflecting an early evolutionary…https:////www.gesundheitsindustrie-bw.de/en/article/news/simple-nerve-cells-regulate-swimming-depth-of-marine-plankton
Article - 17/10/2011 Aristides Arrenberg uses light to investigate the working memory Dr. Aristides Arrenberg from the University of Freiburg did his doctorate in the USA where he further developed a method that can be used to silence or activate specific zebrafish nerve cells at will. The method is based on light stimuli that trigger cellular switches. In addition the researchers have recently published an article on research into how eye movements are stored in the hindbrain. Standard network models used for so-called integrator…https:////www.gesundheitsindustrie-bw.de/en/article/news/aristides-arrenberg-uses-light-to-investigate-the-working-memory
Article - 18/07/2011 Titanium screws and stem cells for dental implants How are we supposed to chew and smile when the tooth fairy comes to fetch our second set of teeth? When it’s difficult to tell the difference between modern tooth implants and real teeth in both technical and aesthetical terms, people who lose their teeth due to accidents or age very quickly regain their smile. However, there needs to be enough bone to hold and support the implant. Prof. Dr. Dr. Ralf Gutwald and his team in the Department of Oral…https:////www.gesundheitsindustrie-bw.de/en/article/news/titanium-screws-and-stem-cells-for-dental-implants
Article - 20/06/2011 How plants change their shape – researchers at KIT investigate cytoskeletal processes Organisms have two possibilities when they encounter inhospitable environmental conditions: to run away or to adapt. As plants have no legs, they therefore need to adapt rapidly to unstable environmental conditions. A plant is hugely flexible in terms of its shape and one of the things that makes this possible is its cytoskeleton, a scaffold consisting of specialized filaments. A group of researchers at the Karlsruhe Institute of Technology (KIT)…https:////www.gesundheitsindustrie-bw.de/en/article/news/how-plants-change-their-shape-researchers-at-kit-investigate-cytoskeletal-processes
Article - 30/05/2011 CorTec GmbH – a bridge between ideas and action Brain machine interfaces that are able to read a paralysed patients desired movement from his or her brain and convert it into actual movement might be available in a few years time if everything goes to plan. CorTec GmbH a spin-off company of the University of Freiburg has a technology platform that is able to measure and interpret a persons brain activity and drive muscles or artificial prostheses.https:////www.gesundheitsindustrie-bw.de/en/article/news/cortec-gmbh-a-bridge-between-ideas-and-action
Article - 23/05/2011 KIT researchers attempt to grow cardiomyocytes in Petri dishes Regenerative medicine specialists are aiming to be able to grow complete organs from stem cells some time in the future. However although the microscopically small cells are able to do many things they are not able to grow organs on their own. Dr. Alexandra Rolletschek and her team at the Karlsruhe Institute of Technology KIT are investigating how stem cells can be grown into heart muscle cells cardiomyocytes in Petri dishes. https:////www.gesundheitsindustrie-bw.de/en/article/news/kit-researchers-attempt-to-grow-cardiomyocytes-in-petri-dishes
Article - 16/05/2011 Oliver Röhrle and the biomechanics of the musculo-skeletal system Dr. Oliver Röhrle contributes to the excellent standards in the field of biomechanics at the University of Stuttgart. He has held one of the popular junior professorships in the Simulation Technology (SimTech) cluster of excellence since 2008 and has recently received a research prize for his work on the biomechanics of the musculo-skeletal system.https:////www.gesundheitsindustrie-bw.de/en/article/news/oliver-roehrle-and-the-biomechanics-of-the-musculo-skeletal-system
Article - 10/04/2011 Wilhelm Aicher is committed to regenerative medicine research Laboratory-based regeneration of human cartilage and muscle tissue is his strong suit: Prof. Dr. Wilhelm K. Aicher brings his expertise in cellular and molecular biology to research focusing on the development of innovative therapies for the treatment of tissue damage. Successes such as a knee cartilage made from autologous (patients’ own) cells show that Aicher is on the right track.https:////www.gesundheitsindustrie-bw.de/en/article/news/wilhelm-aicher-is-committed-to-regenerative-medicine-research
Press release - 30/03/2011 Scientists Find Cause of Fatal Inflammation of the Heart Muscle Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), jointly with colleagues in the United States, have found out that inflammations of the heart muscle are caused by attacks of a specific type of immune cells. These immune cells attack the body’s own tissue because during their maturation they did not have the chance to develop tolerance against a protein that is only found in the heart muscle. https:////www.gesundheitsindustrie-bw.de/en/article/press-release/scientists-find-cause-of-fatal-inflammation-of-the-heart-muscle
Article - 29/11/2010 Going through the eye of a needle: Translating research findings into individualised patient treatment Anyone attempting to assess the importance of pharmacogenetics for drug safety will inevitably end up considering the ambiguous responses of Radio Eriwan. It is true that genetic tests are theoretically able to predict whether an inactive enzyme affects the metabolism of a drug and whether it is necessary to apply a different drug dose. But how can this knowledge be applied in everyday clinical settings when patients with this inactive enzyme are…https:////www.gesundheitsindustrie-bw.de/en/article/news/going-through-the-eye-of-a-needle-translating-research-findings-into-individualised-patient-treatmen
Press release - 28/11/2010 Cardiac catheter surgery for children and young adults without X-ray radiation Heart specialists and electrophysiologists from Tübingen University Hospital have succeeded for the first time in Germany in treating cardiac arrhythmia without the need for X-ray radiation. This was done through the selection of a new method to control the contact force between the catheter and the blood vessel and cardiac walls. The intervention was successfully carried out on a 16-year-old girl and is regarded as a very attractive alternative…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/cardiac-catheter-surgery-for-children-and-young-adults-without-x-ray-radiation