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  • Press release - 29/07/2022

    New centre for model-based artificial intelligence

    A centre for model-based artificial intelligence has been set up at Heidelberg University to link mathematical modelling methods with information processing in neuronal networks. The Carl Zeiss Foundation (CZS) is funding the CZS Heidelberg Center for Model-Based AI with five million euros over a period of six years.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-centre-model-based-artificial-intelligence
  • Press release - 03/06/2022

    Deep Learning helps improve gene therapies and antiviral drugs

    The nuclease Cas13b associated with the CRISPR gene scissors, which is an enzyme that degrades nucleic acids, has the potential to be used in the future in hereditary diseases to switch off unwanted genes. In the fight against infections, this nuclease is also being researched as an antiviral agent, as Cas13b can specifically intervene in the genetic material of viruses and render them harmless.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/deep-learning-helps-improve-gene-therapies-and-antiviral-drugs
  • Press release - 22/02/2022

    Better understanding communication between neurons in the brain

    In the field of optogenetics, scientists investigate the activity of neurons in the brain using light. A team led by Prof. Dr. Ilka Diester and Dr. David Eriksson from the Optophysiology Laboratory at the University of Freiburg has developed a new method to simultaneously conduct laminar recordings, multifiber stimulations, 3D optogenetic stimulation, connectivity inference, and behavioral quantification on brains.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/better-understanding-communication-between-neurons-brain
  • Intelligent Diagnostics - 09/02/2022 Nahaufnahme einer Armunterseite mit Pigmentflecken, auf der – als Teil einer multispektralen Aufnahme – das bläuliche, strichcodeartige Projektionsmuster für eine Wellenlänge zu sehen ist.

    AI for added value in digital melanoma diagnostics

    Intelligent Diagnostics is an interdisciplinary project that brings together the latest technologies and research institutes to better support doctors in diagnosing skin cancer through innovative imaging and artificial intelligence.

    https://www.gesundheitsindustrie-bw.de/en/article/news/ai-added-value-digital-melanoma-diagnostics
  • microRNA as a prognostic biomarker - 13/01/2022 Screen of an ECG device showing the typical action potentials of the heart muscle.

    Heart attack diagnosis: fast and unambiguous thanks to artificial intelligence

    People that arrive in emergency rooms with chest pain require swift action in order to rule out a heart attack or to initiate vital life-saving therapy. However, despite many advances, current tests are not yet optimal: they either take hours or produce false-positive results. Researchers at Heidelberg University Hospital are now using AI in an approach that takes microRNAs from a blood sample to specifically diagnose ‘acute coronary syndrome’.

    https://www.gesundheitsindustrie-bw.de/en/article/news/heart-attack-diagnosis-fast-and-unambiguous-thanks-artificial-intelligence
  • Press release - 27/10/2021

    Disordered brain activity in Rolandic epilepsy can be influenced by brief sounds during sleep

    Rolandic epilepsy is a common form of epilepsy in children which occurs primarily during sleep. Short sounds played during sleep can partially suppress the neuronal discharges characteristic of epilepsy. That’s according to a research team from the University of Tübingen and Tübingen University Hospitals. The team is headed by Dr. Hong-Viet Ngo and Professor Jan Born from the Institute of Medical Psychology and Behavioral Neurobiology.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/disordered-brain-activity-rolandic-epilepsy-can-be-influenced-brief-sounds-during-sleep
  • Press release - 25/10/2021

    How the "thermostat" in the brain measures impending overheating

    The mechanisms by which the body measures temperature and regulates its own body heat are vital, but still poorly understood. The discovery of the first heat sensor on nerve cells in the skin, for which the U.S. molecular biologist David Julius received this year's Nobel Prize for Medicine, was therefore pioneering.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-thermostat-brain-measures-impending-overheating
  • Press release - 09/09/2021

    Machine learning improves biological image analysis

    Scientists use super-resolution microscopy to study previously undiscovered cellular worlds, revealing nanometer-scale details inside cells. This method revolutionized light microscopy and earned its inventors the 2014 Nobel Prize in Chemistry. In an international collaboration, AI researchers from Tübingen have now developed an algorithm that significantly accelerates this technology.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/machine-learning-improves-biological-image-analysis
  • Article - 22/06/2021 Ausschnitt aus der Software von living brain. Patienten erlernen anhand von Übungen mit VR im kritischen Zeitfenster Alltagsaufgaben effektiv.

    Using virtual reality in the clinic to rehabilitate patients with cognitive disorders

    Outdated and inadequate methods of neurological rehabilitation are still being used for patients with neurological diseases or injuries – and what’s more, the treatment is usually too late. This is because cognitive training is especially important in the critical phases when the brain is particularly plastic. The Heidelberg-based company living brain proves that early treatment is possible using an extremely innovative method – with concentrated…

    https://www.gesundheitsindustrie-bw.de/en/article/news/using-virtual-reality-clinic-rehabilitate-patients-cognitive-disorders
  • Press release - 17/06/2021

    To fear or not - how does the brain switch?

    Which neurons in the brain mediate fear responses - and how do they flip the switch when the danger is over? The research team of Prof. Ingrid Ehrlich at the Institute of Biomaterials and Biomolecular Systems (IBBS), Department of Neurobiology studies these questions. Their latest results obtained in collaboration with scientists at the Friedrich Miescher Institute in Basel (Switzerland), the National Institute of Health (USA), and Innsbruck…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/fear-or-not-how-does-brain-switch
  • Press release - 24/02/2021

    Disease progression in childhood cancer: Lengthening of telomeres promotes relapse

    Neuroblastoma can spread relentlessly or shrink spontaneously. Scientists from the Hopp Children’s Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg and the National Center for Tumor Diseases (NCT) Heidelberg have shown that some malignant neuroblastomas employ a trick to avoid cell death: they use a special mechanism to lengthen the telomeres at the end of their chromosomes.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/disease-progression-childhood-cancer-lengthening-telomeres-promotes-relapse
  • Article - 28/03/2019 The IT expert sitting at a meeting table.

    Supporting the human use of artificial intelligence

    Artificial intelligence is no longer a vision of the future, but is already in our midst: whether it is parking aids or search engines, we use the technology quite naturally in many areas of daily life. It promises new, unlimited opportunities, but also poses risks. Experts from the Integrata Foundation in Tübingen work on ethical issues and the human use of IT for improving the life of as many people as possible.

    https://www.gesundheitsindustrie-bw.de/en/article/news/supporting-the-human-use-of-artificial-intelligence
  • Article - 07/02/2019 Ein Porträtfoto des Mediziners.

    Artificial intelligence in ophthalmology

    Retinal diseases such as age-related macular degeneration (AMD) are now treatable. However, it is hard to predict individual disease progression. A group of researchers at the University Eye Centre in Freiburg are currently developing a new system which is hoped will allay fears and improve therapy planning. The system uses artificial intelligence to predict therapeutic outcome from image and patient data. Initial results are already available.

    https://www.gesundheitsindustrie-bw.de/en/article/news/artificial-intelligence-in-ophthalmology
  • Article - 02/10/2018 Microscope image of a kidney section, marked with yellow circles.

    Artificial intelligence in the life sciences: machines as assistants

    Artificial intelligence is currently one of the most innovative issues, but also one of the most controversial research areas. It already has a firm footing in many areas of our everyday life and often we are not even aware of it. Artificial intelligence has long been an integral part of many processes in research and diagnostics in medicine and the life sciences – and it will be even more widely used in the future.

    https://www.gesundheitsindustrie-bw.de/en/article/news/artificial-intelligence-in-the-life-sciences-machines-as-assistants
  • Big Data - 26/03/2018 Schematic showing how data of a patient from different sources such as imaging and molecular diagnostics along with expert comments are combined and used for making a decision.

    Eliciting reliable information from big data with classifiers and multimodal data fusion

    Prof. Hans A. Kestler knows a great deal about large amounts of data. He heads up the Institute of Medical Systems Biology at the University of Ulm and is constantly inundated with cooperation enquiries from clinicians. On behalf of BIOPRO, Walter Pytlik asked him whether the conditions for using big data more in biomedical research are already largely present.

    https://www.gesundheitsindustrie-bw.de/en/article/news/eliciting-reliable-information-from-big-data-with-classifiers-and-multimodal-data-fusion
  • Article - 17/05/2016 Schematic of the entire chip and an amplified sector showing the central area of the square chip along with the round seeding areas and microchannels.

    Innovative biochip for discovering drugs for treating neuronal conditions

    Parkinson’s, Alzheimer’s and epilepsy are three prominent examples of neuronal conditions (disorders affecting the nerve cells) for which drugs for treatment are intensively sought. Paolo Cesare from the NMI in Reutlingen has developed an innovative 3D system for testing drugs that does not require animal testing. In 2015, the MEAFLUIT system was awarded first prize in BioRegio STERN Management GmbH's Science2Start idea competition.

    https://www.gesundheitsindustrie-bw.de/en/article/news/innovative-biochip-for-discovering-drugs-for-treating-neuronal-conditions
  • Article - 16/12/2013 20758_de.jpg

    Light-activated enzymes for novel optogenetic approaches

    In a project funded by the German Research Foundation (DFG), researchers from the Max Planck Institute for Medical Research in Heidelberg are studying algal and bacterial photoreceptors that can be used as optogenetic tools for studying regulatory and metabolic pathways. Through the insertion of a light-activated bacterial enzyme into zebrafish, the researchers have been able to visualise a hormonal reaction chain that is induced by stress…

    https://www.gesundheitsindustrie-bw.de/en/article/news/light-activated-enzymes-for-novel-optogenetic-approaches
  • Article - 16/12/2013 Network with red glowing neurons.

    Tools of the future

    Optogenetics is a relatively new technique that enables scientists to manipulate nature with light. Light-sensitive proteins coupled to enzymes or channelrhodopsins embedded in membranes that guide ions across plasma membranes all of these can be used to modulate cell behaviour. Researchers around the world are working on the emerging technique in order to refine and optimise it for application in their research projects. Optogenetics seems to…

    https://www.gesundheitsindustrie-bw.de/en/article/news/tools-of-the-future
  • Article - 02/12/2013 Network of brain areas.

    ERC Starting Grant for spectral fingerprints of neuronal interactions

    Dr. Markus Siegel from the Centre for Integrative Neuroscience (CIN) at the University of Tübingen deals with fingerprints, but rather than those used to solve crime, he is interested in fingerprints of nerve cell activity in the brain. Siegel uses these fingerprints to explore the mechanisms that coordinate the interactions between different brain regions, which is what enables humans to learn, perceive and decide. He was recently awarded one of…

    https://www.gesundheitsindustrie-bw.de/en/article/news/erc-starting-grant-for-spectral-fingerprints-of-neuronal-interactions
  • Article - 07/10/2013 Hans Kestler, bioinformatician from Ulm, pointing at a scientific poster.

    Hans Kestler brings order to biological data

    Hans Kestler works on the borders between the faculties, administration and different disciplines at Ulm University. Molecular biologists and life scientists at Ulm University fight over the lively engineer who is in his late forties. They all need the assistance of the systems biologist who knows how to deal with the enormous amounts of data they produce using mathematical models and algorithms.

    https://www.gesundheitsindustrie-bw.de/en/article/news/hans-kestler-brings-order-to-biological-data
  • Article - 19/08/2013 The photo shows a schematic of the brain with electrodes arranged in a coordinate system.<br />

    Brain mapping – ‘eavesdropping’ on the brain

    Although numerous scientists have spent decades exploring the brain and many things are already known the brain is still considered one of the greatest mysteries of science. While structural elements such as cell and axon distribution can only be mapped post mortem motor and sensory functions can only be studied in vivo i.e. using living organisms. Dr. Tonio Ball and his colleagues at the BrainLinks-BrainTools cluster of excellence at the…

    https://www.gesundheitsindustrie-bw.de/en/article/news/brain-mapping-eavesdropping-on-the-brain
  • Article - 22/07/2013 20103_de.jpg

    Marcus Fändrich strengthens protein biochemistry at Ulm University

    After quite a long vacancy the directors post of the Institute for Pharmaceutical Biotechnology at the University of Ulm has finally been filled. Marcus Fändrich and his team moved into the laboratories and offices of the new life sciences building on the Oberer Eselsberg Ulm University campus in November 2012. Fändrich fills a gap in the Ulm Bioregions biopharmaceutical education activities as he will not only be teaching biochemistry…

    https://www.gesundheitsindustrie-bw.de/en/article/news/marcus-faendrich-strengthens-protein-biochemistry-at-ulm-university
  • Article - 11/02/2013 19178_de.jpg

    The Human Brain Project

    The Human Brain Project has been granted funding under the EU’s multi-billion euro competition, Future and Emerging Technolgies (FET). The project will receive funds of over one billion euros for a period of ten years and endeavour to simulate the human brain using newly developed supercomputers.

    https://www.gesundheitsindustrie-bw.de/en/article/news/the-human-brain-project
  • Press release - 29/11/2012 18867_de.jpg

    Neural interaction in periods of silence

    While in deep dreamless sleep our hippocampus sends messages to our cortex and changes its plasticity possibly transferring recently acquired knowledge to long-term memory. But how exactly is this done? Scientists from the Max Planck Institute for Biological Cybernetics have now developed a novel multimodal methodology called neural event-triggered functional magnetic resonance imaging NET-fMRI and presented the very first results obtained using…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/neural-interaction-in-periods-of-silence
  • Article - 15/10/2012 18366_de.jpg

    Carmen Ruiz de Almodóvar and the link between the nervous and vascular systems

    Dr. Carmen Ruiz de Almodóvar from the Heidelberg University Biochemistry Centre has been awarded an ERC Starting Grant to study the molecular similarities between the nervous and vascular systems. The researcher showed that angiogenic factors such as VEGF also control the growth of neuronal cells and may be responsible for disorders in the development of nervous systems.

    https://www.gesundheitsindustrie-bw.de/en/article/news/carmen-ruiz-de-almod-var-and-the-link-between-the-nervous-and-vascular-systems

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