Article - 30/06/2009 More targeted treatment of the brain network “Casting out the demons with the ruler of the demons” – is what the majority of neuroactive drugs still do. A group under the leadership of Dr. Ralf Meyer at the University Medical Centre in Freiburg is investigating why substances used to treat epilepsy or depression have a negative effect on many patients. Their research shows that the drugs interact with the hormonal system, resulting in undesired side effects. Meyer and his team of…https://www.gesundheitsindustrie-bw.de/en/article/news/more-targeted-treatment-of-the-brain-network
Press release - 29/06/2009 Uncovering how cells cover gaps Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, came a step closer to understanding how cells close gaps not only during embryonic development but also during wound healing. Their study, published this week in the journal Cell, uncovers a fundamental misconception in the previous explanation for a developmental process called dorsal closure.https://www.gesundheitsindustrie-bw.de/en/article/press-release/uncovering-how-cells-cover-gaps
Article - 29/06/2009 Alternative protein structures and breast cancer A single protein can have many variants. This variability is achieved by a process known as splicing which can introduce small modifications into the mRNA transcript of a gene. Prof. Dr. Elmar Stickeler from the University Womens Hospital in Freiburg found that some of these splice variants can also induce cancer. Stickeler and his team are investigating how splicing factors change their target molecules and how this leads to breast cancer. This…https://www.gesundheitsindustrie-bw.de/en/article/news/alternative-protein-structures-and-breast-cancer
Press release - 29/06/2009 Can loss of sense of smell predict Alzheimer’s The first lapses of memory go hand in hand with a loss of the sense of smell: The olfactory centre in the brain of Alzheimer’s patients is wasting away. The olfactory bulb starts to shrink at a very early stage of the disease, at a time when retentiveness is only slightly affected. It is possible to detect the shrinkage of the olfactory bulb with magnetic resonance imaging, as the latest findings by scientists of the Department of Psychiatry at…https://www.gesundheitsindustrie-bw.de/en/article/press-release/can-loss-of-sense-of-smell-predict-alzheimer-s
Press release - 29/06/2009 How can cancer pain be treated effectively? Cancer patients often suffer from severe pain that cannot be treated effectively with traditional drugs. Scientists at the Institute of Pharmacology at the University of Heidelberg have now discovered the potential reason for the severe pain associated with several forms of cancer.https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-can-cancer-pain-be-treated-effectively
Press release - 29/06/2009 New electron microscopy images reveal the assembly of HIV Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is a precursor of the infectious virus, which can cause AIDS. The study, published in the 22-26 June online edition of PNAS, describes how the protein…https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-electron-microscopy-images-reveal-the-assembly-of-hiv
Dossier - 25/06/2009 DNA and RNA replication The replication of the genome is essential for the continuity of life. The molecular mechanism is very similar in all groups of organisms. Although the basics of replication are already well understood, researchers are still focusing on questions relating to DNA replication. These questions not only deal with the understanding of a basic biological process, but also with related medical aspects.https://www.gesundheitsindustrie-bw.de/en/article/dossier/dna-and-rna-replication
Article - 24/06/2009 The initiation of replication – only once, please DNA replication is a critical event in the cell division process. The genetic material must only be replicated once. So, how does a bacterial cell ensure that only one single replication occurs and that the process is not repeated several times? Microbiologists under the leadership of Prof. Dr. Peter Graumann from the Institute of Biology II in Freiburg, in cooperation with international cooperation partners from Paris, have deciphered a…https://www.gesundheitsindustrie-bw.de/en/article/news/the-initiation-of-replication-only-once-please
Article - 23/06/2009 Hepatitis B and the Münchhausen enzyme Virologists in Prof. Dr. Michael Nassals group at the University Medical Centre in Freiburg are investigating the molecular mechanisms used by the hepatitis B virus to reproduce. The researchers work might in future be able to help the three to four hundred million people worldwide who suffer from chronic hepatitis B infections. https://www.gesundheitsindustrie-bw.de/en/article/news/hepatitis-b-and-the-muenchhausen-enzyme
Press release - 22/06/2009 New important triggers for the migration of cancer cells Embryonic cells and metastasising cancer cells are able to migrate and intrude into other tissues. Investigations of frog embryos have now provided scientists at the Karlsruhe Institute of Technology with the information that a well-known protein, cadherin-11, triggers cell migration. This glycoprotein is also responsible for the defective behaviour of cells that results in prostate cancer and arthritis. https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-important-triggers-for-the-migration-of-cancer-cells
Article - 10/06/2009 Dirk Linke - a vaccine is ready - just in case There is a well-known saying: travel broadens the mind. This is not the only consequence of travel – the biochemist Dr. Dirk Linke from Tübingen travelled to India on holiday and brought back an idea for a new scientific project. Since his return, his idea, the possibility of developing a vaccine with a wide-ranging effect against some of the most frequent diarrhoea pathogens, has even generated financial backing from prominent supporters.https://www.gesundheitsindustrie-bw.de/en/article/news/dirk-linke-a-vaccine-is-ready-just-in-case
Article - 19/05/2009 What makes blood vessels sprout? Calcified arteries or capillaries – this is often associated with blood stasis, reduced oxygen supply, and subsequent cardiac strain that compensates these deficiencies. Dr. Sebastian Grundmann from the Department of Cardiology and Angiology at the University Medical Centre Freiburg and his team are investigating how the growth of blood vessels is triggered, and potentially find ways to naturally deviate the site of congestion. https://www.gesundheitsindustrie-bw.de/en/article/news/what-makes-blood-vessels-sprout
Article - 14/05/2009 A multicentred approach for the treatment and prevention of diabetes In order to counteract the increase in the number of diabetics it is necessary to take into account the entire psychosocial environment of the patients states Prof. Dr. Peter Nawroth a physician from Heidelberg University Hospital. The prevention of late complications must be a major goal of any treatment and patient consultation. By focusing on the development and investigation of the RAGE-dependent reaction system Nawroth and his team have…https://www.gesundheitsindustrie-bw.de/en/article/news/a-multicentred-approach-for-the-treatment-and-prevention-of-diabetes
Article - 13/05/2009 Mitochondria – making the impossible possible The transport of proteins across the two mitochondrial membranes is a very complex process. Huge molecular machines recognise the precursor proteins which are formed inside the cell and which are destined for the energy power stations of the cells. Some of these substances pass the outer and the inner membrane, some of them remain in the intermembrane area. How does the sorting of the molecules work? Five years ago, molecular biologist Dr.…https://www.gesundheitsindustrie-bw.de/en/article/news/mitochondria-making-the-impossible-possible
Article - 12/05/2009 Fatal relatives: adiposity and diabetes Martin Wabitsch was the first German pediatrician to investigate adiposity back when it was seen as a strange subject to study. Nowadays, in Germany the attitude towards adiposity has completely changed. More and more people are suffering from adiposity and diabetes and are consequently at risk of contracting other severe diseases as a result. In children and young adults the situation is alarming; many children are at risk of contracting…https://www.gesundheitsindustrie-bw.de/en/article/news/fatal-relatives-adiposity-and-diabetes
Press release - 12/05/2009 Gene variant responsible for defective communication in the brain Schizophrenia and bipolar disorder are psychological diseases that are both common and severe. The causes of these diseases are largely unknown. It has been known for some time that certain hereditary factors enhance the risk of developing schizophrenia or a manic-depressive disorder. Researchers from the ZI in Mannheim and the Department of Medicine Psychology at the University of Bonn have managed to identify the effects of such gene variants…https://www.gesundheitsindustrie-bw.de/en/article/press-release/gene-variant-responsible-for-defective-communication-in-the-brain
Press release - 11/05/2009 CellGenix Technologie Transfer GmbH: 15 years of innovation and market leadership 2009 is a very special year for CellGenix a biotechnology company located in Freiburg. The company is celebrating its 15th anniversary - 15 years of innovation and market leadership in the production of high-quality cell therapeutics and growth factors for clinical cell therapy.https://www.gesundheitsindustrie-bw.de/en/article/press-release/cellgenix-technologie-transfer-gmbh-15-years-of-innovation-and-market-leadership
Press release - 01/05/2009 They have the super cell In the Year of Science which is being celebrated in the city of Constance in 2009 the company Trenzyme located in the Constance industrial park is a prime example of science and industry working successfully hand in hand on the Nycomed campus.https://www.gesundheitsindustrie-bw.de/en/article/press-release/they-have-the-super-cell
Press release - 30/04/2009 In the tubular system of human cells Scientists from the Hygiene Institute at the Heidelberg University Hospital have succeeded for the first time ever in showing the three-dimensional architecture of the dengue virus replication and assembly sites in human cells. Their paper was recently published in the renowned journal “Cell Host & Microbes”. https://www.gesundheitsindustrie-bw.de/en/article/press-release/in-the-tubular-system-of-human-cells
Article - 27/04/2009 Interaction mechanisms between tumours and blood vessels In recognition of the growing importance of angiogenesis research in the field of oncology the German Research Foundation has established two new research consortia as part of its Angiogenesis research priority programme one project focuses on the mechanisms of vascular differentiation and the second on the interaction between tumour cells and cells of the vascular wall which are prerequisites for tumour growth and metastasis.https://www.gesundheitsindustrie-bw.de/en/article/news/interaction-mechanisms-between-tumours-and-blood-vessels
Article - 21/04/2009 Two separate defence systems? Are the innate and the adaptive immune systems really completely independent from each other? Dr. Mathias Lucas from the University of Freiburg investigates receptor proteins that are found in the cells of both systems. It is possible that such systems might not only play a role in infections or cancer, but also in autoimmune diseases such as rheumatoid arthritis. https://www.gesundheitsindustrie-bw.de/en/article/news/two-separate-defence-systems
Article - 20/04/2009 Programmed cell death and its role in cancer The closing symposium of the “Apoptosis Deficiency” funding priority of the German Cancer Aid Dr. Mildred Scheel Foundation was held in the German Cancer Research Centre in Heidelberg at the end of March 2009. German Cancer Aid has supported this programme since 1999 with over 15 million euros in funding. A total of 29 research groups at many German institutes and hospitals have received funding.https://www.gesundheitsindustrie-bw.de/en/article/news/programmed-cell-death-and-its-role-in-cancer
Article - 20/04/2009 Anita Ignatius makes biomaterials smart Anita Ignatius is not interested in knowledge just for the sake of knowledge. “I have always been interested in the practical application of knowledge,” said the 45-year-old veterinarian. Highly theoretical courses she had to attend during her studies put an end to her dreams of opening her own practice after university. But this experience also had its advantages, because it helped her realise what she really wanted – namely doing research of…https://www.gesundheitsindustrie-bw.de/en/article/news/anita-ignatius-makes-biomaterials-smart
Article - 20/04/2009 Biomarkers for the identification of metastases Prof. Dr. Heike Allgayer a surgeon and molecular biologist from Heidelberg is investigating the molecular processes of the formation of tumour metastases. A major objective of her research is to find specific biomarkers that enable the early identification of metastases and to monitor the outcome of therapy. She has already received numerous prizes for her achievements.https://www.gesundheitsindustrie-bw.de/en/article/news/biomarkers-for-the-identification-of-metastases
Press release - 17/04/2009 Who is pulling the threads in the cell? Cell division i.e. mitosis is key in the development of multicellular organisms be these dogs cats mice humans or plants. This process is controlled by specific proteins that interact closely with each other. Prof. Thomas U. Mayer a molecular geneticist at the University of Constance has gained new insights into the function of two of these proteins namely the CPC and Mklp2 proteins. He has discovered that a protein known as cyclin-dependent…https://www.gesundheitsindustrie-bw.de/en/article/press-release/who-is-pulling-the-threads-in-the-cell