Dossier - 24/04/2008 Contract manufacture: the order books remain full The market for therapeutic proteins is continuing to grow in double figures. Current estimates of the total market value are in the range of 60 to 70 billion US dollars and the market is estimated to grow by 13 per cent p.a. up until 2010. Biopharmaceutical contract manufacturers have established themselves on the market and market observers estimate that the number of biopharmaceutical medicines will grow from 100 2005 to approx. 150 until 2010.https://www.gesundheitsindustrie-bw.de/en/article/dossier/contract-manufacture-the-order-books-remain-full
Article - 18/04/2008 Better bypass with gene therapy? Almost half of the veins transplanted to restore blood flow in the heart become clogged again within ten years after surgery. Gene therapy pre-treatment of the vein fragments that prevents the muscle cells from entering the vascular wall might decrease the risk of this happening. https://www.gesundheitsindustrie-bw.de/en/article/news/better-bypass-with-gene-therapy
Press release - 17/04/2008 BioLux GmbH - from the hen to the egg and then to the clients It began as a service laboratory for DNA sequencing and within a few years became a worldwide network of highly specialised biotech companies for molecular biology products. Investments in platform technologies play a key role in this development. Since then the team at Stuttgart-based BioLux GmbH has found that the production of antibodies is its highest revenue business activity.https://www.gesundheitsindustrie-bw.de/en/article/press-release/biolux-gmbh-from-the-hen-to-the-egg-and-then-to-the-clients
Article - 16/04/2008 Roland Schuele - "Research cannot be predicted" Professor Roland Schuele from the University Womens Hospital in Freiburg originally studied biochemistry. Nowadays Schuele is researching the development of prostate cancer. During his scientific career he has learnt that research cannot be steered in a particular direction. It develops and we follow it said Schuele who has been able to gain astonishing insights into the molecular processes in tumour cells.https://www.gesundheitsindustrie-bw.de/en/article/news/roland-schuele-research-cannot-be-predicted
Press release - 16/04/2008 Effective Cancer Immune Therapy Through Order in the Blood Vessels Researchers at the German Cancer Research Center have discovered a key molecule that is responsible for the immature structure of blood vessels in malignant tumors. If this molecule is switched off in mice vessels normalize so that immune cells are better able to get to the tumor tissue.https://www.gesundheitsindustrie-bw.de/en/article/press-release/effective-cancer-immune-therapy-through-order-in-the-blood-vessels
Article - 14/04/2008 Molecular cell recognition - putting the brain in order The neurogeneticists in the group of Professor Karl-Friedrich Fischbach at the University of Freiburg are investigating how the complex optical areas of the brain are organised. They found that proteins form a functional unit.https://www.gesundheitsindustrie-bw.de/en/article/news/molecular-cell-recognition-putting-the-brain-in-order
Article - 06/04/2008 Molecular chaperons in algal chloroplasts Michael Schroda from the Department of Plant Biochemistry at the University of Freiburg is examining the role of HSP70B a chaperon in the chloroplasts of Chlamydomonas reinhardtii algae which is important for protecting the algae against high light intensity.https://www.gesundheitsindustrie-bw.de/en/article/news/molecular-chaperons-in-algal-chloroplasts
Article - 30/03/2008 Small air bubbles with a huge impact Scientists from the Max Planck Institute for Metal Research in Stuttgart and their colleagues from Chicago and Miami have identified a physical mechanism that gives a new explanation as to how ion channels work.https://www.gesundheitsindustrie-bw.de/en/article/news/small-air-bubbles-with-a-huge-impact
Article - 29/03/2008 Artificial micro RNAs in plant breeding Scientists from the Max Planck Institute for Developmental Biology in Tübingen and their colleagues from the International Rice Research Institute in the Philippines succeeded in accelerating rice plant breeding by using artificial small RNA molecules.https://www.gesundheitsindustrie-bw.de/en/article/press-release/artificial-micro-rnas-in-plant-breeding
Article - 29/03/2008 Freiburg researchers discover new effect of insulin Working with colleagues from the Harvard Medical School in Boston USA researchers from Freiburg University have discovered a previously unknown role of insulin in ageing and lifespan. Insulin inhibits a master stress regulator protein known as SKN-1.https://www.gesundheitsindustrie-bw.de/en/article/press-release/freiburg-researchers-discover-new-effect-of-insulin
Article - 29/03/2008 GATC Biotech opens new subsidiary in Sweden GATC Biotech announced that it has added to its facilities with a wholly owned subsidiary in Stockholm Sweden building on the Companys existing presence in Europe with offices in Germany France and England.https://www.gesundheitsindustrie-bw.de/en/article/press-release/gatc-biotech-opens-new-subsidiary-in-sweden
Article - 24/03/2008 Successful cooperation between science and industry At the recent Science meets Business Day four tandem teams of the German BioValley Platform presented their projects. These will be introduced in two articles. The first article focuses on natural substances with a pharmaceutical potential.https://www.gesundheitsindustrie-bw.de/en/article/news/successful-cooperation-between-science-and-industry
Article - 20/03/2008 The effect of migration from Africa on genetic diversity in Europe The paper by Lohmueller et al. 2008 shows that there is proportionally more deleterious genetic variation in European than in African populations. This revelation enables conclusions to be made on the group that emigrated from Africa several thousand years ago.https://www.gesundheitsindustrie-bw.de/en/article/news/the-effect-of-migration-from-africa-on-genetic-diversity-in-europe
Article - 16/03/2008 New indication for lead compound of Apogenix Isolated tumour cells use to invade healthy brain tissue during the development and growth of glioblastoma multiforme GBM. This mechanism involves the CD95CD95L death system. These results supports the therapeutic potential of Apogenix APG101 for the treatment of glioblastomas.https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-indication-for-lead-compound-of-apogenix
Article - 14/03/2008 Elisa Izaurralde, a prominent RNA scientist, receives Leibniz Prize The directors of the Tübingen Max Planck Institute MPI for Developmental Biology are pleased to have a Leibniz prizewinner in their ranks for the second year running. Dr. Elisa Izaurralde and her colleague Dr. Elena Conti have both been awarded the 2008 prize for their outstanding work in the field of RNA research. https://www.gesundheitsindustrie-bw.de/en/article/news/elisa-izaurralde-a-prominent-rna-scientist-receives-leibniz-prize
Article - 11/03/2008 Nils Johnsson delivers initial insights Nils Johnssons work focuses on communication research involving living objects. The 48-year-old biochemist is investigating how proteins manage the complicated process of cytokinesis the division of the cell plasma. Thanks to a specific method Johnsson is able to detect when proteins are interacting with each other.https://www.gesundheitsindustrie-bw.de/en/article/news/nils-johnsson-delivers-initial-insights
Article - 10/03/2008 The latest on ubiquitin Christiane Pelzer and Ingrid Kassner biologists at the University of Constance recently discovered a previously unknown protein that plays a role in the binding of ubiquitin to target proteins. This discovery is a milestone in the research of basic enzymatic processes.https://www.gesundheitsindustrie-bw.de/en/article/news/the-latest-on-ubiquitin
Press release - 04/03/2008 When success inflates costs Red biotechnology became commercially successful because process engineering succeeded in expressing foreign genes in microorganisms and got a grip on cells tissue cells were not only cultivated using technical methods but also purified for medical application on an industrial scale. However the biopharmaceutical industry is now facing rising costs.https://www.gesundheitsindustrie-bw.de/en/article/press-release/when-success-inflates-costs
Article - 03/03/2008 Genetic engineering in the conflict of contradictions The history of Bt-maize is a strange mix of opportunities risks scientific contradictions market authorisations and recalls. It is also an excellent example of why the public scepticism towards genetically modified organisms GMO is growing.https://www.gesundheitsindustrie-bw.de/en/article/news/genetic-engineering-in-the-conflict-of-contradictions
Article - 02/03/2008 Miniature device offers great opportunities The Dietmar Hopp Foundation has donated one million euro for a new small-animal tomograph at the University Hospital in Heidelberg. The new system is suitable for small animals such as rats and mice and can be used to investigate diseases and therapies.https://www.gesundheitsindustrie-bw.de/en/article/news/miniature-device-offers-great-opportunities
Article - 01/03/2008 Holger Barth is turning toxins into protein shuttles Holger Barth works with a special kind of Trojan horses. The toxicologist from Ulm is investigating bacterial toxins. These proteins manage in a similar way to the ancient Greeks before them to open the barricaded portal of the cells with a trick whereupon they start wreaking destruction.https://www.gesundheitsindustrie-bw.de/en/article/news/holger-barth-is-turning-toxins-into-protein-shuttles
Article - 28/02/2008 Gilbert Gorr - a great fan of the moss Physcomitrella patens Dr. Gilbert Gorr has been fascinated by the moss Physcomitrella patens for many years in fact it occupies a great deal of his waking moments. The enthusiasm with which the CSO of greenovation Biotech GmbH talks about the key object of his work is both intoxicating and contagious. The latest discovery The moss produces a therapeutic antibody that is far more effective than its predecessors created in animal cell cultures.https://www.gesundheitsindustrie-bw.de/en/article/news/gilbert-gorr-a-great-fan-of-the-moss-physcomitrella-patens
Article - 24/02/2008 Biametrics - High-tech analytics for the life sciences Biametrics Marken and Rechte GmbH has developed new analytical devices based on reflectometric interference spectroscopy thus adopting the trend of label-free detection methods. This is because labelling tends to interfere with the natural activity of the biomolecules under investigation.https://www.gesundheitsindustrie-bw.de/en/article/news/biametrics-high-tech-analytics-for-the-life-sciences
Article - 22/02/2008 Proteins help to narrow down the time of death The forensic scientist Dr. Frank Wehner from the University of Tübingen has developed a method that enables him to determine the time of death to within a few days. The method is based on the degradation of proteins like insulin or cystatin C.https://www.gesundheitsindustrie-bw.de/en/article/news/proteins-help-to-narrow-down-the-time-of-death
Article - 21/02/2008 The females choose their mates The team of researchers led by evolutionary biologist Dr. Gerrit Begemann at Constance University is using swordtails to investigate the development of traits that evolved by sexual selection. Their major focus is the molecular mechanism of growth control in the caudal fin. Or put more simply why do these fish have swords?https://www.gesundheitsindustrie-bw.de/en/article/news/the-females-choose-their-mates