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The latest articles, press releases and dossiers on diagnostics in Baden-Württemberg

  • Article - 15-Dec-2014

    All the cells in an organism have to adapt to changing requirements as they develop and grow - including muscle cells in the heart. Crucial to this process are the cells’ growth in size and epigenetic factors that play a role in modulating the expression of various genes. The role of epigenetics in cancer development has been the focus of research for quite some time. The question is, what role do epigenetic factors play in the development of the heart? Prof. Dr. Lutz Hein from the Institute of Pharmacology and Toxicology at the University of Freiburg studies the maturation of cardiac muscle cells and the epigenetic programmes involved. One of his goals is to better understand cardiac diseases.

  • Press release - 26-Nov-2014

    Curetis AG wins new investors QIAGEN and LSP-HEF, committing EUR 7 million. Hence Curetis is well financed into 2017. Curetis AG, a developer of next-level molecular diagnostic solutions, today announced it has closed a EUR 14.5 million extension of its Series B financing round, which was originally led by HBM Partners in April 2013.

  • Article - 20-Oct-2014

    Quick, simple and decentralized – this is how QIAGEN Lake Constance GmbH envisages diagnostics applications in the future. The Stockach-based QIAGEN subsidiary develops test systems for point-of-need diagnostics, i.e. tests that can be carried out in close proximity to the sample collection point, for example in GP surgeries. They enable the rapid identification of pathogens, and as a result the timely initiation of suitable treatment.

  • Article - 13-Oct-2014

    microRNAs are not just required for the regulation of gene expression, their expression signatures also allow conclusions to be drawn on the type and progression of cancer. Sensovation AG is therefore working with partners from industry and clinical research to develop an automated microRNA analysis platform that can detect and evaluate microRNA signatures faster than has previously been possible. The system is designed to make it easier to identify certain cancers and deliver more efficient therapy.

  • Article - 06-Oct-2014

    While there are specific regulations in Germany for the reimbursement of medicines, funding for molecular diagnostics products is complex and virtually non-existent. There is hardly any medical insurance cover for medical devices, which therefore tend to be sold on the open market. The question therefore arises as to how a reasonable price can be determined for innovative diagnostic methods and tools. In the second part of the interview conducted by Dr. Barbara Jonischkeit from BIOPRO Baden-Württemberg, Dr. Manfred Caeser, a pricing and reimbursement specialist at LSCN Ltd., explains the situation for us.

  • Article - 29-Sep-2014

    The company myPOLS Biotec UG, a spin-off from the University of Konstanz, specializes in services involving DNA and RNA polymerases and creates artificial enzymes by evolution in test tubes. These next-generation polymerases can be used for many research and diagnostics applications. myPOLS Biotec’s polymerases are promising enzymes for future applications with the potential to make the detection of pathogens and DNA analysis faster and easier.

  • Article - 08-Sep-2014

    After a traumatic experience, people often suffer not only mental, but also physical effects. Dr. María Moreno-Villanueva from the University of Konstanz has investigated the molecular effects of traumatic stress in people and has found a higher than normal number of DNA strand breaks. In the worst cases this can lead to diseases such as cancer. However, her study also shows that successful psychotherapy can reverse DNA damage. Her findings will contribute to the development of new methods for the diagnosis and therapy of traumatic stress disorders.

  • Article - 11-Aug-2014

    PCR has become a common application in medical diagnostics, in areas ranging from the detection of microbes to genetic testing. The demand for new tests is huge, given that there is a seemingly endless list of applications for which PCR can be used. dsl-Labor für Molekulargenetische Diagnostik specialises in the development of PCR tests and also gives advice and training to medical laboratory personnel. Veterinarians are among the company’s major clients since the rapid and reliable diagnosis of disease plays a particularly important role in animal husbandry.

  • Article - 30-Jun-2014

    Epigenetic DNA modifications have been shown to play a role in carcinogenesis and are therefore a promising target for the early detection of cancer. Dr. Daniel Summerer and his research group at the University of Konstanz have developed a method that enables the direct and site-specific identification of epigenetic changes. The method represents a new approach in the field of epigenetic analysis as well as a major step towards simpler cancer diagnosis.

  • Article - 30-Jun-2014

    A large-scale long-term cohort study will be carried out to explain the causes of widespread diseases, in particular cancer, coronary heart disease, stroke and diabetes, and to identify the risk factors that lead to or favour the development of a certain disease. The principal objective of the German National Cohort (GNC) is to create the conditions that enable the development of new strategies for the prevention, risk assessment and early detection of chronic diseases.

  • Dossier - 02-Jun-2014

    Science constantly provides researchers with new challenges biologists and bioanalysts have to deal with and which come from sources as varied as the ever increasing number of resistant pathogenic bacterial strains or the famine conditions in Third-World countries. In the search for scientific truths bioanalysis is the development optimization and application of the entire range of analytical methods available. However we need to keep in mind that although this leads to an expansion of knowledge the truth is only temporary.

  • Article - 02-Jun-2014

    Spectroscopic methods have been used for many decades in scientific research to obtain a wealth of information about chemical substances, substance mixtures and their reaction processes. Micro-biolytics GmbH from Esslingen have successfully developed a spectroscopic method that combines innovative technologies. The method enables the highly accurate and sensitive measurement of aqueous samples.

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