The NanoLYRIC project: nanoparticles as drug carriers - 13/08/2026

Radiation-activated local chemotherapy

Conventional chemotherapy is associated with severe side effects because cytotoxic drugs act on the whole body. Researchers at the Karlsruhe Institute of Technology and the University Medical Centre Göttingen, in collaboration with Aalen University of Applied Sciences, are developing a novel approach in which a chemotherapeutic agent encapsulated in nanoparticles is released locally and selectively only upon targeted irradiation of the tumour.

FlareOn Biotech - fluorescence-guided tumour margin detection - 01/07/2026

A sensor designed to visualise residual tumour tissue during surgery

In order to safely remove tumours in the head and neck region, surgeons must be able to reliably distinguish diseased tissue from healthy tissue. FlareOn Biotech, a start-up based in Frickenhausen, has developed a biochemical sensor capable of visualising tumour cells in tissue samples directly in the operating theatre within just ten minutes. The company is now seeking partners to help bring its diagnostic platform to market.

Until now, it has been technically nearly impossible to rotate highly sensitive samples in all directions under a microscope without making contact. Researchers at the KIT have developed a new laser-based technique that allows microscopic samples such as cells to be rotated contact-free in all three spatial directions. The laser creates tiny temperature differences in the liquid, which trigger gentle fluid flows that move the sample.

Making existing cancer therapy more efficient while significantly reducing the side effects on healthy tissue - this is the aim of a project at Aalen University. It is being funded with one million euros from the Carl Zeiss Foundation. The biophysicist and his team are developing innovative nanoparticles made of gold. The particles use radiotherapy and chemotherapy simultaneously and kill the cancer cells in a targeted manner.

High-resolution microscopy technology bypassing the diffraction limit - 26/10/2023

From micro- to nanoscope

It has long been impossible to distinguish objects closer than 200 nanometres using light microscopes. However, novel devices developed by a company called abberior Instruments GmbH, which use technology developed by Nobel Prize winner Prof. Dr. Stefan Hell and his teams in Heidelberg and Göttingen, are now able to bypass this resolution limit and provide detailed insights into living cells in the lower nanometre range.

Dossier - 08/09/2022

Imaging methods in medical diagnostics

Many different imaging methods are available these days and are used in almost all medical disciplines to visualise disease-related changes. Depending on the problem and the clinical picture, very different structural and functional parameters can be visually recorded for diagnosis and used for therapy.

Intelligent Diagnostics - 09/02/2022

AI for added value in digital melanoma diagnostics

Intelligent Diagnostics is an interdisciplinary project that brings together the latest technologies and research institutes to better support doctors in diagnosing skin cancer through innovative imaging and artificial intelligence.