Article - 29/11/2010 Downstream processing – from molecular structures to industrial processes Biotechnologically manufactured pharmaceuticals represent the most innovative type of new medications to respond to challenges in the fields of oncology immunodeficiency and metabolism. The research group led by Prof. Dr. Jürgen Hubbuch from the Karlsruhe Institute of Technology KIT is developing methods that enable the processing and crystallisation of biological molecules and turning them into biologically viable forms. https:////www.gesundheitsindustrie-bw.de/en/article/news/downstream-processing-from-molecular-structures-to-industrial-processes
Article - 29/11/2010 How axons find their way A group of researchers led by Prof. Dr. Martin Bastmeyer from the Institute of Zoology at the Karlsruhe Institute of Technology KIT is investigating how a complex network of molecular landmarks guides fully grown retinal axons to the correct point in the visual centre map. The researchers use chickens as model organism to simulate the mechanisms involved in axonal pathfinding and target recognition in cell cultures and computer simulations.https:////www.gesundheitsindustrie-bw.de/en/article/news/how-axons-find-their-way
Article - 18/10/2010 A chip to support three-dimensional tissue culture The KITChip developed by researchers from the Karlsruhe Institute of Technology KIT improves the three-dimensional self-organisation of cells by enabling the active flow and circulation of the cell culture media. Using smart microtechnical methods the scientists are able to adapt the microenvironment of cell types to their specific requirements which leads to specific cellular behaviour and development. https:////www.gesundheitsindustrie-bw.de/en/article/news/a-chip-to-support-three-dimensional-tissue-culture
Article - 30/08/2010 Genetic testing for the prevention of diseases? Genetic testing is beginning to play an important role in personalised medicine and is indispensable for the diagnosis and therapy of many diseases. However, the preventive and diagnostic power of many genetic tests is still inferior to traditional diagnostic tests. In addition, commercial genetic tests do not always live up to the claims made about them. https:////www.gesundheitsindustrie-bw.de/en/article/news/genetic-testing-for-the-prevention-of-diseases
Article - 23/08/2010 Signals that trigger symbiotic relationships Some fungi kill plants by wearing them down. Other fungi however are on friendly terms with plants. The research group led by Prof. Dr. Natalia Requena from the Karlsruhe Institute of Technology KIT investigates the molecular mechanisms that enable fungi and plants to initiate contact with each other. How do plants differentiate good from bad fungi? How do they manage to set up a functional and effective symbiotic relationship?https:////www.gesundheitsindustrie-bw.de/en/article/news/signals-that-trigger-symbiotic-relationships
Article - 10/07/2010 Algae light up industry The potential of Microalgae cannot yet be optimally used on the large scale. The bioprocess engineer Dr. Rosa Rosello and her team at the Karlsruhe Institute of Technology KIT are investigating the conditions under which different microalgae species can optimally grow in photobioreactors and lead to high product yields. It is all a question of light and shade.https:////www.gesundheitsindustrie-bw.de/en/article/news/algae-light-up-industry
Press release - 09/07/2010 Protein with a double light switch Researchers led by Professor Gerd Ulrich Nienhaus from the KIT have developed a new fluorescent marker protein. The photoactivatable fluorescent protein mIrisFP enables reversible photoswitching between fluorescent and nonfluorescent state as well as conversion from a green-emitting to a red-emitting form. The protein is suitable for carrying out dynamic investigations on cells and organisms and opens up new opportunities in cell biological and…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/protein-with-a-double-light-switch
Press release - 05/07/2010 AnDiaTec - Real cowboys have heard of Kornwestheim AnDiaTec GmbH & Co. KG from Kornwestheim is in high demand worldwide as a partner specialising in detection methods for bacteria and viruses. The company is a world market leader in real time PCR Kits for the detection of noroviruses. The U.S. Ministry of Agriculture even draws on the expertise of AnDiaTec in relation to virus infections in cattle. After an intensive period of research and development, the company is now expanding its sales…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/andiatec-real-cowboys-have-heard-of-kornwestheim
Article - 28/06/2010 ATG:biosynthetics GmbH – Modular molecular systems of the future ATGbiosynthetics GmbH based in Merzhausen close to Freiburg produces biological systems that can combine gene constituents following a construction kit principle. The company provides the pharmaceutical industry and basic researchers with products that have specifically chosen properties.https:////www.gesundheitsindustrie-bw.de/en/article/news/atg-biosynthetics-gmbh-modular-molecular-systems-of-the-future
Press release - 17/05/2010 Bioliq® pilot plant at KIT close to completion The completion of the bioliq® pilot plant on the northern campus of the Karlsruhe Institute of Technology (KIT) is now a certainty. Following the commitment by the German and Baden-Württemberg governments to provide 11 million euros in financing, the KIT has now also signed contracts with companies that will work with KIT in the implementation of the two final processing stages. These two stages involve the production of second-generation…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/bioliq-pilot-plant-at-kit-close-to-completion
Article - 29/03/2010 A ray of light for fungi Breaking through the protective darkness of the soil can be very uncomfortable for fungi because it requires them to adapt quickly to UV radiation or moisture fluctuations. But how do they know that they are on the soil surface? An important parameter is light. Researchers led by Prof. Dr. Reinhard Fischer at the Karlsruhe Institute of Technology (KIT) are investigating how the mould Aspergillus nidulans perceives light and how this governs its…https:////www.gesundheitsindustrie-bw.de/en/article/news/a-ray-of-light-for-fungi
Press release - 26/01/2010 KIT is the most successful German institution in acquiring European research funds Under the 6th Research Framework Programme of the European Union, the Karlsruhe Institute of Technology acquired more than 80 million euros in research funds and was involved in 209 research projects. These figures show that it outperforms all other individual institutions in Germany, including universities, research centres and industrial companies. KIT has also had a successful start to the 7th Framework Programme.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/kit-is-the-most-successful-german-institution-in-acquiring-european-research-funds
Article - 25/01/2010 The two sides of a cell Almost all cells are asymmetric – this is why for example the intestines, the brain and lungs function so well. Tumour diseases show why it is so important for a cell to have two different sides, a “head” and a “foot”. In cancer, genes that are responsible for the correct development of cell polarity are often defective. Dr. Felix Loosli from the Karlsruhe Institute of Technology investigates epithelial cells in the retina of the small Japanese…https:////www.gesundheitsindustrie-bw.de/en/article/news/the-two-sides-of-a-cell
Press release - 10/12/2009 Hydrogen from microalgae Hydrogen (H2) produced from water has great potential to be an environmentally friendly energy carrier of the future. However, the future application of hydrogen and other CO2-neutral sustainable fuels also requires the development of production methods that can contribute to the energy supply of tomorrow. Some unicellular green algae and cyanobacteria use light to break up water into hydrogen and oxygen. In cooperation with eight partners, KIT…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/hydrogen-from-microalgae
Article - 28/11/2009 "You cannot afford to fail twice in Germany" Prof. Dr. Bodo Liedvogel and Dr. Heinz Haubruck founded the company DIARECT AG in Freiburg in 1998. They not only brought 20 years of experience in industry to the company but also their entire savings. In the following interview Dr. Heinz Haubruck tells Christoph Bächtle about the return investors expect from companies how to win over potential clients and the risks associated with setting up ones own business.https:////www.gesundheitsindustrie-bw.de/en/article/news/you-cannot-afford-to-fail-twice-in-germany
Article - 28/10/2009 Worn down and financially exhausted, but more popular than ever When academic toxicologists in a German state join forces, it is virtually headline news. This is because the discipline is on the red list. Only in Baden-Württemberg does the number of toxicologists at university institutes justify the joining of forces. The ironic thing about this is that the competence of the rare species ”toxicologicus” is in greater demand than ever. https:////www.gesundheitsindustrie-bw.de/en/article/news/worn-down-and-financially-exhausted-but-more-popular-than-ever
Article - 27/10/2009 Jürgen Bauer – investigating the development mechanisms of malignant melanomas Professor Dr. Jürgen Bauer knows from experience that a scientific career cannot always be planned with military precision. The dermatologist from Tübingen has never shied away from making unusual decisions in order to achieve his goals. When he looks back on his career, he can see a broad range of research activities: initially, he focused mainly on the clinical and epidemiological aspects of melanomas; nowadays, his research concentrates on the…https:////www.gesundheitsindustrie-bw.de/en/article/news/juergen-bauer-investigating-the-development-mechanisms-of-malignant-melanomas
Press release - 12/10/2009 KIT takes off – University of Karlsruhe and the Karlsruhe Research Centre merged into one single entity on 1st October 2009 Almost three years after winning the German government’s Excellence Initiative, the idea has now become reality: On 1st October 2009, the University of Karlsruhe and the Karlsruhe Research Centre (Forschungszentrum Karlsruhe) merged to become a single legal entity known as the KIT, according to the Act on the Establishment of the Karlsruhe Institute of Technology. https:////www.gesundheitsindustrie-bw.de/en/article/press-release/kit-takes-off-university-of-karlsruhe-and-the-karlsruhe-research-centre-merged-into-one-single-entit
Press release - 09/10/2009 BIOTECHNICA 2009 - turning ideas into value BIOTECHNICA 2009 which took place in Hanover Germany from 6th to 8th October 2009 featured the seminal motto Turning ideas into value. The exhibition programme was rounded off by numerous talks and plenary discussions held at the joint Baden-Württemberg booth.https:////www.gesundheitsindustrie-bw.de/en/article/news/biotechnica-2009-turning-ideas-into-value
Press release - 22/09/2009 Nanoparticles: researchers to map protein corona The way nanoparticles behave in the human body not only depends on their chemical structure. Of greater importance is the way they interact with biological molecules. Professor Gerd Ulrich Nienhaus at the Karlsruhe Institute of Technology (KIT) has developed new methods that enable the quantitative measurement of these dynamic processes.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/nanoparticles-researchers-to-map-protein-corona
Article - 12/08/2009 More effective extraction of small RNAs Small RNAs are gaining in importance in research as well as in the biotechnology and pharmaceutical industries. However the potential of these molecules can only be exploited fully if very pure RNAs can be extracted from the cells in sufficiently high quantities. Currently used methods are expensive and only designed for large cell quantities. In addition the operation of the extraction systems is very complicated. A new biochip developed by Dr.…https:////www.gesundheitsindustrie-bw.de/en/article/news/more-effective-extraction-of-small-rnas
Press release - 11/08/2009 Merger of the University of Karlsruhe and the Karlsruhe Research Centre Federal Minister of Education and Research, Prof. Dr. Annette Schavan, and the Baden-Württemberg Minister of Science, Research and the Arts, Prof. Dr. Peter Frankenberg, signed the administrative agreement on the merger of the Karlsruhe Research Centre and the University of Karlsruhe on 30 July 2009.https:////www.gesundheitsindustrie-bw.de/en/article/press-release/merger-of-the-university-of-karlsruhe-and-the-karlsruhe-research-centre
Article - 30/07/2009 Dragnet investigation for substance killers The Ulm-based company Labor Dr. Merk Kollegen with over 40 employees is a specialist company identifying foreign bodies such as viruses bacteria and toxins in biopharmaceuticals and medical products. In addition the medium-sized company has been developing producing and marketing diagnostics for medical use for almost 40 years.https:////www.gesundheitsindustrie-bw.de/en/article/news/dragnet-investigation-for-substance-killers
Article - 01/07/2009 KIT - Competence in bioprocess engineering The purification of microbially produced substances such as proteins and polysaccharides and their separation from or release from within the cell are complex tasks in the field of biotechnology. The Bioprocess Engineering department of the Institute of Process Engineering in the Life Sciences TH deals with the development of integrated bioprocesses and is also involved in the separation of biopolymers.https:////www.gesundheitsindustrie-bw.de/en/article/news/kit-competence-in-bioprocess-engineering
Press release - 30/06/2009 The genome as glue Many engineers who need to work with structured materials with small pores most likely dream of a glue that not only holds the tiny particles together, but also automatically brings them into contact at the correct distance from each other. Scientists under the leadership of Prof. Clemens Richert and Prof. Stefan Bräse at the Karlsruhe Institute of Technology (KIT) have now developed a “bioglue” using a process that is summarised in the journal…https:////www.gesundheitsindustrie-bw.de/en/article/press-release/the-genome-as-glue