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  • Press release - 26/05/2025

    Explainable artificial intelligence increases the accuracy and endurance of dermatologists in melanoma diagnosis

    Scientists at the German Cancer Research Center (DKFZ) have shown in an international eye-tracking study that dermatologists not only improve their diagnostic accuracy by using explainable artificial intelligence, but also show significantly less fatigue when assessing challenging cases. The researchers were able to demonstrate this by measuring a reduction in cognitive stress indicators.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/explainable-artificial-intelligence-increases-accuracy-and-endurance-dermatologists-melanoma-diagnosis
  • Press release - 21/05/2025

    How aging changes the blood system in humans and mice

    The reservoir of blood stem cells shrinks with age. It becomes increasingly dominated by stem cells that produce immune cells associated with chronic inflammation. Almost all of the 60-year-olds studied show this change. The new discovery could help explain the chronic inflammation that occurs with age and makes us more susceptible to disease. It could also help identify early warning signs of unhealthy aging processes.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-aging-changes-blood-system-humans-and-mice
  • Press release - 09/04/2025

    The positive effect of paws Pets reduce the risk of stress-related disorders in city dwellers

    Contact with pets reduces the risk of developing stress-related disorders in adult life in urban children. This is the conclusion of a study conducted by the Section for Molecular Psychosomatic Medicine at Ulm University Hospital together with other researchers from Germany and the USA. Living with animals is said to alleviate inflammatory stress reactions.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/positive-effect-paws-pets-reduce-risk-stress-related-disorders-city-dwellers
  • Press release - 01/04/2025

    Rethink food policy: citizens demand more co-determination and less division

    84 percent of Germans consciously consider their diet. For the majority, nutrition is a central topic, but many perceive the public debate as divisive and patronising. According to the latest nutrition study by the Robert Bosch Stiftung and the More in Common, citizens want policies that promote healthy, regional, and affordable food – without regulations or bans. At the same time, they are calling for more say in shaping the food system.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/rethink-food-policy-citizens-demand-more-co-determination-and-less-division
  • Press release - 17/03/2025

    RNA Origami: Artificial Cytoskeletons to Build Synthetic Cells

    With the goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses RNA biomolecule to fold new building blocks, making protein synthesis superfluous. In pursuit of the artificial cell, a research team has cleared a crucial hurdle. Using the new RNA origami technique, they succeeded in producing nanotubes that fold into cytoskeleton-like structures.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/rna-origami-artificial-cytoskeletons-build-synthetic-cells
  • Press release - 11/03/2025

    Frequent blood donations promote the regeneration of blood cells through genetic adaptation

    Donating blood saves lives – but what long-term effects does this practice have on our bodies? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM stem cell institute* and the German Red Cross Blood Donor Service, among others, have now discovered that frequent blood donations cause genetic adaptations in blood stem cells that promote the regeneration of blood cells.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/frequent-blood-donations-promote-regeneration-blood-cells-through-genetic-adaptation
  • Press release - 06/03/2025

    New insights into the cellular mechanism of action of psilocybin

    A recent study by the Hector Institute for Translational Brain Research at the CIMH provides the first cellular insights into how psilocin promotes the growth and networking of human nerve cells.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-insights-cellular-mechanism-action-psilocybin
  • Press release - 25/02/2025

    Self-healing hearts How Zebrafish regenerate heart muscle cells

    Zebrafish can completely replace damaged heart muscle cells: The affected organ becomes fully functional again. Researchers at Ulm University have discovered that a specific cell-to-cell communication signal helps them to cope better with replication stress. This stress inhibits tissue regeneration in humans and mammals as they age. In Zebrafish a signalling protein ensures that the cells of the damaged organ continue to divide and thus multiply.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/self-healing-hearts-how-zebrafish-regenerate-heart-muscle-cells
  • Press release - 20/01/2025

    New approach to fighting cancer: energy trap for tumor cells

    Glycolysis is an important sugar degradation pathway that cancer cells in particular depend on. Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice and humans depend on a key enzyme of glycolysis, Aldolase A. When it is switched off, glycolysis reverses from an energy-producing to an energy-consuming process.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-approach-fighting-cancer-energy-trap-tumor-cells
  • Press release - 25/11/2024

    Chromosomal chaos promotes therapy resistance in leukemia cells and opens up new treatment approaches

    Chromosomal instability plays a role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM* and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular heterogeneity of a specific form of acute myeloid leukemia.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/chromosomal-chaos-promotes-therapy-resistance-leukemia-cells-and-opens-new-treatment-approaches
  • Press release - 01/10/2024

    Reporter Skin: In-vitro Skin Makes Cell Reaction to Test Substance Measurable in Real Time

    At the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, a three-dimensional skin model has now been set up for the first time that directly displays the skin's reaction to substances: The reporter skin. Thanks to the built-in reporter, the cellular response can be measured precisely and quickly – using a living model.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/reporter-skin-vitro-skin-makes-cell-reaction-test-substance-measurable-real-time
  • Chronic inflammatory bowel diseases - 25/09/2024 Vor schwarzem Hintergrund sind kugelförmige Zellansammlungen zu sehen.

    Proinflammatory regulatory T lymphocytes as a therapeutic target in Crohn's disease

    Chronic inflammatory bowel diseases are very stressful for those affected and increase the risk of bowel cancer. PD Dr. Robyn Laura Kosinsky from the Bosch Health Campus in Stuttgart, together with researchers from the USA, identified disfunctional regulatory T cells as important drivers of inflammation in Crohn's disease. They also found that with the help of an epigenetically active drug, it was possible to restore the cells’ original…

    https://www.gesundheitsindustrie-bw.de/en/article/news/proinflammatory-regulatory-t-lymphocytes-therapeutic-target-crohns-disease
  • Press release - 12/06/2024

    Pathogen identification — next-generation sequencing optimizes diagnostics

    Invasive infections such as sepsis require immediate and targeted treatment. Experts from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB and group partners have succeeded in establishing a reconceptualized detection principle that can make a crucial contribution to saving lives through fast, ultra-accurate pathogen identification. They have been chosen to receive the 2024 Stifterverband Science Prize for their efforts.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/pathogen-identification-next-generation-sequencing-optimizes-diagnostics
  • Press release - 22/05/2024

    Stretched beyond the limits of the cell: the molecular biomechanics of collagen

    Together with colleagues from Israel and USA, HITS researcher Frauke Gräter investigates the effects of physical force on the collagen protein in two different animal model systems. Their goal is to measure the effects of mechanoradicals on the integrity of the tissue and the well-being of the organism, with impact on health and aging.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/stretched-beyond-limits-cell-molecular-biomechanics-collagen
  • Press release - 11/04/2024

    How the body switches out of “fight” mode Study in Nature unlocks how cortisone inhibits inflammation

    Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. A team of researchers from Charité – Universitätsmedizin Berlin, Uniklinikum Erlangen and Ulm University have now explored the molecular mechanism of action in greater detail.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/wie-der-kampfmodus-im-koerper-beendet-wird-studie-nature-entschluesselt-wie-kortison-entzuendungen-daempft
  • Press release - 31/01/2024

    Precursor of Cholesterol Protects Cancer Cells From Cell Death and Makes them Aggressive

    A precursor of cholesterol can protect cancer cells from a form of cell death known as ferroptosis. Scientists of the University of Würzburg, the German Cancer Research Center (DKFZ), and the Stem Cell Institute HI-STEM* published this finding in the journal Nature. The results opens up exciting prospects for further improving the treatment of cancer and other diseases associated with oxidative stress and ferroptosis.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/cholesterin-vorstufe-schuetzt-krebszellen-vor-zelltod-und-macht-sie-aggressiver
  • Help with osteoarthritis of the knee - 27/09/2023 A skin-colored hemisphere printed with a silver needle in a 3D printer.

    Individualised knee-joint cartilage: artificial tissue that fits

    Knee joints are subject to considerable stress throughout our lives. The natural shock absorber cartilage wears out over a lifetime, so many people develop knee osteoarthritis. Treatment is available in the form of artificial cartilage. This "off-the-shelf" tissue often does not grow well. Researchers are developing an individualised cartilage replacement made from biomaterial that is produced by 3D printing based on MRI images.

    https://www.gesundheitsindustrie-bw.de/en/article/news/individualised-knee-joint-cartilage-artificial-tissue-fits
  • Press release - 10/08/2023

    Computer-aided cell analysis for faster diagnosis of blood diseases

    Scientists from the German Cancer Research Center (DKFZ) and the Cambridge Stem Cell Institute have developed an AI system that recognizes and characterizes white and red blood cells in microscopic images of blood samples. The algorithm can help physicians diagnose blood disorders and is available as an open source method for research purposes.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/computergestuetzte-zellanalyse-fuer-die-schnellere-diagnose-von-blutkrankheiten
  • Press release - 18/07/2023

    National Research Center for cutting-edge AI research in Tübingen celebrates inception

    On Tuesday, July 18, 2023, the Tübingen AI Center held a symposium to celebrate its permanent establishment as a national AI center. Since July 1, 2022, it has received 20 million euros a year in funding from the federal government and the state.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/nationales-forschungszentrum-fuer-ki-spitzenforschung-tuebingen-feiert-seine-gruendung
  • Press release - 04/05/2023

    Gamma delta T cells can fight aggressive breast cancer

    Triple-negative breast cancer (TNBC) is the most aggressive and deadly form of breast cancer with limited treatment options. Tumor growth and relapse of TNBC are driven by breast cancer stem cells, and improved therapies that can eliminate those hardy cells are urgently needed. Researchers from the University of Frieburg discovered that coordinated differentiation and changes in the metabolism of breast cancer stem cells make them invisible for…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/gamma-delta-t-cells-can-fight-aggressive-breast-cancer
  • Press release - 24/04/2023

    Hidden RNA repair mechanism discovered in humans

    Konstanz researchers discover the function of a previously unexplored protein: In three characteristic steps, "C12orf29" links the ends of RNA strands. Proteins that perform this kind of RNA ligation were previously unknown in humans. The results of the study suggest that it is important for RNA repair during cellular stress.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/hidden-rna-repair-mechanism-discovered-humans
  • Press release - 06/04/2023

    Alternative glucose breakdown ensures the survival of cancer cells

    A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown that with this oxidation, cells switch to an alternative sugar breakdown pathway and can thus escape oxidative stress. Cancer cells in particular benefit from this mechanism, which can also protect them from therapy-related damage.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/alternative-glucose-breakdown-ensures-survival-cancer-cells
  • Inovedis GmbH’s innovative implant - 28/03/2023 Inovedis_Implantat_Teaser.png

    Next-generation minimally invasive shoulder surgery

    The treatment of shoulder injuries such as rotator cuff tears is one of the most common orthopaedic interventions. It is therefore quite surprising that the surgical procedure has not changed much for decades - although it is relatively complicated. The start-up Inovedis has now developed a completely new surgical technique based on an implant that can be performed simply, safely, quickly and cost-effectively with minimal stress for patients.

    https://www.gesundheitsindustrie-bw.de/en/article/news/next-generation-minimally-invasive-shoulder-surgery
  • Press release - 17/01/2023

    Blood stem cells: not in charge in an emergency!

    After infections or blood loss, the body must compensate for the loss of blood cells as quickly as possible. This has long been considered the task of the hematopoietic stem cells in the bone marrow. But scientists at the German Cancer Research Center (DKFZ) have now discovered in mice that a certain population of progenitor cells takes over this task: This accelerates the regeneration of the blood cells.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/blood-stem-cells-not-charge-emergency
  • Press release - 25/11/2022

    Praise for Ulm's trauma research from DFG CRC 1149 reaches 3rd funding phase

    What a success for Ulm University and its medical centre! The German Research Foundation (Deutsche Forschungsgemeinschaft; DFG) extends the Collaborative Research Centre (CRC) on Trauma Medicine for the second time. The third funding phase infuses the CRC 1149 'Danger Response, Disturbance Factors and Regenerative Potential after Acute Trauma' with 11.1 million euros.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/praise-ulms-trauma-research-dfg-crc-1149-reaches-3rd-funding-phase
  • Press release - 02/11/2022

    The guardian of the (epi-)genome

    Toxicologists from the University of Konstanz have found that the protein p53 continuously protects our cells from tumorigenesis by coordinating important metabolic processes that stabilize their genomes.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/guardian-epi-genome
  • Press release - 05/10/2022

    Second Stem Cell Type Discovered in Mouse Brain

    In the brain of adult mammals neural stem cells ensure that new nerve cells, i.e. neurons, are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team led by Dr Francesca Ciccolini at the Interdisciplinary Center for Neurosciences (IZN) of Heidelberg University recently discovered a second stem cell population in the mouse brain.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/zweiter-stammzelltyp-im-maeusehirn-entdeckt
  • Press release - 19/09/2022

    How stressed tumor cells escape cell death: new mechanism discovered

    Because of their highly active metabolism, many tumors are susceptible to a special type of cell death, ferroptosis. Nevertheless, cancer cells often manage to escape this fate. Scientists at the German Cancer Research Center have now discovered a new mechanism by which normal as well as cancer cells protect themselves against ferroptosis.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-stressed-tumor-cells-escape-cell-death-new-mechanism-discovered
  • Press release - 29/06/2022

    RNA modifications in mitochondria promote invasive spread of cancer

    Mitochondria are the power plants of cells, and they contain their own genetic material and RNA molecules. Scientists from the German Cancer Research Center (DKFZ) have now discovered that certain modifications in mitochondrial RNA boost the invasive spread of cancer cells by supporting protein synthesis in mitochondria.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/rna-modifications-mitochondria-promote-invasive-spread-cancer
  • Press release - 31/01/2022

    Cancer research learns from space travel

    Researchers use epigenetic factors to investigate the role of stress in the development of tumor diseases. Experts believe that stress plays a major role in the development of tumors. One occupational group, for example, that experiences extreme stress over a short period of time is astronauts.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/cancer-research-learns-space-travel
  • Press release - 09/12/2021

    New research project in mathematical oncology

    A new interdisciplinary research project aims to uncover information that can help decode hereditary colon cancer with the aid of mathematical models. Mathematicians and tumour biologists of Heidelberg University, the Heidelberg Institute for Theoretical Studies, Heidelberg University Hospital, and the German Cancer Research Center are collaborating on the project.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-research-project-mathematical-oncology
  • Press release - 10/11/2021

    Plasticizers can cause asthma and allergies

    Plastic products can be found everywhere in daily life, soft plastic in particular often being used for packaging or children's toys. These often contain so-called plasticizers which ensure that the material remains flexible. Because plasticizers are not bonded permanently to the plastic, they can escape from the material, meaning they can be absorbed by humans.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/plasticizers-can-cause-asthma-and-allergies
  • Press release - 15/07/2021

    Mechanism for differentiation of specific immune cell types discovered

    Under certain conditions, our immune system can efficiently fight off infectious diseases and cancer. T cells, especially the gamma delta T cell type, play an important role in this. The issue is that this cell type is extremely infrequent in the human body. Researchers at the University Hospital Tübingen, the University of Heidelberg and the European Molecular Biology Laboratory (EMBL) have now succeeded in finding the cause for the formation of…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/mechanism-differentiation-specific-immune-cell-types-discovered
  • Press release - 12/07/2021

    Hijacked immune activator promotes growth and spread of colorectal cancer

    Through a complex, self-reinforcing feedback mechanism, colorectal cancer cells make room for their own expansion by driving surrounding healthy intestinal cells to death - while simultaneously fueling their own growth. This feedback loop is driven by an activator of the innate immune system. Researchers from the German Cancer Research Center (DKFZ) and the University of Heidelberg discovered this mechanism in the intestinal tissue of fruit…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/hijacked-immune-activator-promotes-growth-and-spread-colorectal-cancer
  • Press release - 17/06/2021

    To fear or not - how does the brain switch?

    Which neurons in the brain mediate fear responses - and how do they flip the switch when the danger is over? The research team of Prof. Ingrid Ehrlich at the Institute of Biomaterials and Biomolecular Systems (IBBS), Department of Neurobiology studies these questions. Their latest results obtained in collaboration with scientists at the Friedrich Miescher Institute in Basel (Switzerland), the National Institute of Health (USA), and Innsbruck…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/fear-or-not-how-does-brain-switch
  • Press release - 03/03/2021

    New Baden-Württemberg network to reduce animal experiments

    A new network has been set up in Baden-Württemberg aimed at reducing animal experiments as well as further improving animal welfare. It combines new approaches and measures at the state’s biomedical research locations, which are expected to limit stress in laboratory animals and steadily reduce the number of animals used in research in line with the 3R principles of Replacement, Reduction, and Refinement.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-baden-wuerttemberg-network-reduce-animal-experiments
  • Press release - 24/02/2021

    Disease progression in childhood cancer: Lengthening of telomeres promotes relapse

    Neuroblastoma can spread relentlessly or shrink spontaneously. Scientists from the Hopp Children’s Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg and the National Center for Tumor Diseases (NCT) Heidelberg have shown that some malignant neuroblastomas employ a trick to avoid cell death: they use a special mechanism to lengthen the telomeres at the end of their chromosomes.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/disease-progression-childhood-cancer-lengthening-telomeres-promotes-relapse
  • Innovations in the field of endoscopy - 08/06/2020 Computeranimation der Kamerapille im Dünndarm.

    Gastroscopies with pill cameras

    A pill camera to examine the gastrointestinal tract that can be swallowed without major difficulty, controlled intuitively from the outside and deliver images in real time - why would any doctor or patient say no? To non-experts, it sounds more like science fiction but such a device is actually already in development: since 2019, Tübingen-based Ovesco Endoscopy AG and three partners have been working together on this in a project called nuEndo.

    https://www.gesundheitsindustrie-bw.de/en/article/news/magenspiegelung-kamerapille
  • Dossier - 18/04/2016 An image of a nucleosome

    Epigenetics – heritable traits without changing the DNA sequence

    Epigenetics, i.e. the inheritance of traits that does not involve a change in the DNA sequence, was once a controversial subject that has since become a central focus of biological research. Epigenetic inheritance is now studied by numerous national and international research programmes. Many cellular regulatory and differentiation processes are controlled by epigenetic mechanisms that take place on different levels.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/epigenetics-heritable-traits-without-changing-the-dna-sequence
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