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  • Personalised medicine - 16/09/2021 Diagram illustrating pharmacogenomics. Individuals with different genetic makeups are shown as different coloured pictograms and have different combinations of efficacy and toxicity. A drawing of an hourglass is used to illustrate the influence of non-genetic factors.

    Pharmacogenomics enables individualised drug prescription

    Every person is unique, and their reaction to medications can be just as individual. For this reason, unexpected side effects occur time and again with common drugs, sometimes with life-threatening consequences. At the Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology (IKP) in Stuttgart, the influence of hereditary factors on these harmful reactions is being investigated in order to enable individualised therapies.

    https://www.gesundheitsindustrie-bw.de/en/article/news/pharmacogenomics-enables-individualised-drug-prescription
  • Press release - 20/06/2023

    CureVac Doses First Patient in Phase 1 Study of Cancer Vaccine Candidate for Surgically Resected Glioblastoma

    CureVac N.V. today announced that it has dosed the first patient with its investigational cancer vaccine CVGBM in a Phase 1 study. CVGBM is based on CureVac’s proprietary second-generation mRNA backbone and features a single mRNA, encoding eight epitopes derived from known tumor-associated antigens with demon­strated relevance in glioblastoma. A first data readout is expected in the second half of 2024.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/curevac-doses-first-patient-phase-1-study-cancer-vaccine-candidate-surgically-resected-glioblastoma
  • Press release - 03/09/2024

    NMR Spectroscopy: A Faster Way to Determine the “Sense of Rotation” of Molecules

    Researchers of Karlsruhe Institute of Technology (KIT) and Voxalytic GmbH developed a new method that allows, for the first time, to elucidate the chiral structure of molecules – the exact spatial arrangement of the atoms – by nuclear magnetic resonance (NMR) spectroscopy. This important step in the development of new drugs used to be a time-consuming process until now.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/nmr-spectroscopy-faster-way-determine-sense-rotation-molecules
  • SpecPlate: an innovative multiwell plate - 26/03/2025 The two founders sitting, looking at the new SpecPlate microtitre plate.

    Focus on innovative drug development - accurate, time- and cost-saving

    Drug research is a complex and costly process that requires extensive laboratory analyses and vast quantities of consumables, with disposable sample carriers in particular being used in their millions. PHABIOC GmbH has come up with a solution in the form of the SpecPlate, a ground-breaking alternative to sample carriers that reduces the time taken to perform analyses as well as the quantity of materials consumed. Serial production is underway.

    https://www.gesundheitsindustrie-bw.de/en/article/news/focus-innovative-drug-development-accurate-time-and-cost-saving
  • Press release - 16/05/2023

    First company in the world to offer preclinical drug tests for children with cancer

    The recently established ITCC-P4 gGmbH provides academic institutions and pharmaceutical companies with a comprehensive repertoire of modern laboratory models of pediatric tumors. The aim is to systematically test new treatment options for children and adolescents with cancer and to contribute data to regulatory approval processes in order to make the development of new cancer therapies for children and adolescents more attractive.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/first-company-world-offer-preclinical-drug-tests-children-cancer
  • Press release - 13/08/2024

    Peptide Boronic Acids: New Prospects for Immunology

    A cutting-edge chemical process is the first to make it possible to quickly and easily produce modified peptides with boronic acids. As part of this work, scientists managed to synthesize a large number of different biologically active peptide boronic acids and investigate their properties. They open up new possibilities in the young research field of synthetic immunology and could go on to be used primarily in immunotherapy.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/peptide-boronic-acids-new-prospects-immunology
  • Press release - 09/09/2024

    New Molecular Engineering Technique allows for complex Organoids

    A new molecular engineering technique can precisely influence the development of organoids. Microbeads made of specifically folded DNA are used to release growth factors or other signal molecules inside the tissue structures. This gives rise to considerably more complex organoids that imitate the respective tissues much better and have a more realistic cell mix than before.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/new-molecular-engineering-technique-allows-complex-organoids
  • Dossier - 23/07/2012 Biopro-Grafik-Biooekonomie-Stadt-R-Einzelne-Grafiken-gross5.png

    Extremophilic bacteria

    Extremophilic bacteria love it hot, sour or salty, toxic substances like heavy metals also do them good and even give them energy. As molecular and systems biology techniques get better and better, industry is also becoming increasingly interested in these exotic organisms. What potential does knowing the biochemistry of extremophilic bacteria have for the pharmaceutical, cosmetics and sanitary articles industries?

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/extremophilic-bacteria
  • Press release - 06/02/2023

    Fewer side effects thanks to personalised medicine

    Patients have 30 percent fewer serious side effects when medication doses are tailored to their genetic profile. This is what an international research consortium has found out, including the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology at the Bosch Health Campus. With an individual DNA medication pass, as used in the study, treatments can be made more effective and safer in the future.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/weniger-nebenwirkungen-dank-personalisierter-medizin
  • Dossier - 11/10/2023 Photo of a quantum computer.

    The quantum revolution in the healthcare industry

    From ultra-fast quantum computers to highly sensitive sensors - quantum technologies could take medicine a giant step forward. Possible areas of application range from drug development and early cancer detection to reading brain waves to control prostheses or exoskeletons. The German state of Baden-Württemberg plays a key role in the development of sensors in particular.

    https://www.gesundheitsindustrie-bw.de/en/article/dossier/The-quantum-revolution-in-the-healthcare-industry
  • Press release - 12/06/2025

    BioNTech Announces Strategic Transaction to Acquire CureVac in Public Exchange Offer

    Acquisition will strengthen the mRNA-based cancer immunotherapy candidates, marking BioNTech’s milestone in its oncology strategy. Acquisition of CureVac will complement BioNTech’s capabilities and proprietary technologies in mRNA design, delivery formulations, and mRNA manufacturing. All-stock acquisition has potential to create value for both companies’ shareholders given their complementary capabilities, focus on mRNA, and shared vision.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/biontech-announces-strategic-transaction-acquire-curevac-public-exchange-offer
  • Press release - 14/03/2024

    Next milestone in the treatment of liver tumors and acute and chronic liver diseases

    The results of a Tuebingen-led study raise hope that a newly developed drug could herald a new era in oncological liver surgery and transplantation. The drug could even have the potential to significantly improve the treatment of acute and chronic liver diseases. The drug candidate "HRX-215" is a so-called MKK4 inhibitor, i.e. the drug inhibits the MKK4 protein found in liver cells and thus leads to an increase in the regeneration of…

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/next-milestone-treatment-liver-tumors-and-acute-and-chronic-liver-diseases
  • Press release - 14/03/2025

    Tool identifies specific viruses to combat dangerous bacteria

    University of Tübingen research team shortens the search for attackers that can wipe out multiresistant pathogens – with the aim of treating infections without antibiotics

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/tool-identifies-specific-viruses-combat-dangerous-bacteria
  • Animal-free testing of chemicals and cosmetics - 07/05/2025 A histological section of human skin showing the different layers of the epidermis, including the keratinizing squamous epithelium

    Human reporter skin for visualsing skin reactions

    Before new cosmetics can be placed on the market, all ingredients must undergo rigorous testing for safety and efficacy. Dr. Anke Burger-Kentischer of the Fraunhofer IGB has long been at the forefront of animal-free research and has developed an innovative method to quickly and reliably test cosmetics and other chemicals without using animals. She was awarded the 2024 Hamburg Research Prize for her groundbreaking ‘reporter skin’ in vitro model.

    https://www.gesundheitsindustrie-bw.de/en/article/news/human-reporter-skin-visualsing-skin-reactions
  • Press release - 12/05/2025

    NMI expertise for new VDI guideline on bioprinting - now available

    VDI Guideline 5708 “Bioprinting, methods and definitions”: What sounds technical and sober at first glance is an important step forward in the future field of 3D bioprinting. The guideline was developed under Dr. Hanna Hartmann from the NMI in Reutlingen and Prof. Dr. Jürgen Groll from the University Hospital of Würzburg. It creates a binding, practical basis for reproducible and quality-assured bioprinting procedures.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/nmi-expertise-new-vdi-guideline-bioprinting-now-available
  • Press release - 23/01/2025

    ERC Funding for „EmbryoNet-AI“

    Konstanz biologist Patrick Müller receives a Proof of Concept Grant from the European Research Council for his project "EmbryoNet-AI". Its goal is the further development of an AI-supported platform for the automated evaluation of experiments – for example, in drug development.

    https://www.gesundheitsindustrie-bw.de/en/article/press-release/erc-funding-embryonet-ai
  • Cell-based solution in place of animal testing - 05/06/2025 FB_Teaser_CellAlarm-InnoZell_.jpg

    Innovative cell-based test to detect pyrogens in drugs

    Drug safety testing for microbial contaminants and fever-inducing substances (pyrogens) still frequently uses animal experiments. InnoZell, a start-up that will soon be spun off from the University of Konstanz, has developed a compelling alternative: an animal-free, human cell-based assay that is faster, more sensitive and more reliable than traditional methods – and can be customised to meet user-specific needs.

    https://www.gesundheitsindustrie-bw.de/en/article/news/innovative-cell-based-test-detect-pyrogens-drugs

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