rMSI technology - 08/11/2021 New multispectral imaging technology improves endoscopic tumour detection capabilities The quality of minimally invasive surgery depends to a large extent on the imaging properties of the endoscopes used. The Mannheim-based company Thericon GmbH has developed a multispectral imaging technology that overlays views from multiple light channels in real time to create a detailed image on which tumours can be better identified.https://www.gesundheitsindustrie-bw.de/en/article/news/new-multispectral-imaging-technology-improves-endoscopic-tumour-detection-capabilities
Press release - 06/07/2021 High-throughput metabolic profiling of single cells Scientists from the EMBL and the German Cancer Research Center have presented a new method for generating metabolic profiles of individual cells. The method, which combines fluorescence microscopy and a specific form of mass spectroscopy, can analyze over a hundred metabolites and lipids from more than a thousand individual cells per hour. Researchers expect the method to better answer a variety of biomedical questions in the future.https://www.gesundheitsindustrie-bw.de/en/article/press-release/high-throughput-metabolic-profiling-single-cells
Diagnostics - 29/01/2018 New test for extended blood fat analysis Cholesterol is seen as the cause of atherosclerosis, a disease that can lead to heart attacks and strokes. However, it now seems that the way cholesterol is packaged may be even more important than high blood cholesterol levels. Nuclear magnetic resonance (NMR) spectroscopy now allows the high-throughput analysis of such lipid packages. https://www.gesundheitsindustrie-bw.de/en/article/news/new-test-for-extended-blood-fat-analysis
Article - 02/06/2014 micro-biolytics GmbH – industrial application of the AquaSpec™ technology Spectroscopic methods have been used for many decades in scientific research to obtain a wealth of information about chemical substances, substance mixtures and their reaction processes. Micro-biolytics GmbH from Esslingen have successfully developed a spectroscopic method that combines innovative technologies. The method enables the highly accurate and sensitive measurement of aqueous samples. https://www.gesundheitsindustrie-bw.de/en/article/news/micro-biolytics-gmbh-industrial-application-of-the-aquaspec-technology
Article - 05/05/2014 Magnetic amino acids for measuring proteins Dr. Malte Drescher and Dr. Daniel Summerer, two chemists from Konstanz University, have developed an innovative method for studying protein structures using magnetic labels inside cells. The method is based on non-canonical magnetic amino acids that are directly incorporated into the protein as it is biosynthesised in the cell. A patent has been filed for the method, which could potentially lead to major progress in the field of structural…https://www.gesundheitsindustrie-bw.de/en/article/news/magnetic-amino-acids-for-measuring-proteins
Article - 16/09/2013 Infrared light as an indicator of wine quality Guaranteeing the quality of wines is becoming increasingly important so that they are able to compete in the international market. However, the quality control methods currently used are often rather time-consuming and costly. In addition, it is difficult to detect microbial grape contaminations that might jeopardise the quality of the wines. Researchers at the National Training and Research Institute for Viticulture and Horticulture in…https://www.gesundheitsindustrie-bw.de/en/article/news/infrared-light-as-an-indicator-of-wine-quality
Article - 15/04/2013 Molecule-specific diagnosis of metabolic diseases In cooperation with the company Centogene AG Prof. Dr. Michael Przybylski from the Steinbeis Transfer Center for Biopolymer Analysis and Biomolecular Mass Spectrometry at the University of Konstanz has developed a method that involves a novel substance class and enables the parallel measurement of enzyme activity based on fluorometry and mass spectroscopy. The method for which the inventors have recently filed a patent application forms the basis…https://www.gesundheitsindustrie-bw.de/en/article/news/molecule-specific-diagnosis-of-metabolic-diseases
Article - 22/02/2013 Malte Drescher provides insights into cells Electron spin resonance (ESR) spectroscopy can deliver information about the structure and dynamics of large molecules and was used by Dr. Malte Drescher from the University of Konstanz to develop a method for the structural analysis of biological macromolecules inside cells. It provides insights into the complex structure of molecules under physiological conditions and is a promising approach for the development of cancer drugs.https://www.gesundheitsindustrie-bw.de/en/article/news/malte-drescher-provides-insights-into-cells
Press release - 15/11/2012 How bacteria attack their host cells with sticky lollipops Yersinia enterocolitica, a pathogenic bacterium, causes fever and diarrhea. By help of a protein anchored in its membrane, Yersinia attaches to its host cells and infects them. Scientists of the Max Planck Institute for Developmental Biology in Tübingen and the Leibniz-Institut fuer Molekulare Pharmakologie in Berlin have determined the structure of an important component of the membrane protein and have gained insight into its biogenesis. The…https://www.gesundheitsindustrie-bw.de/en/article/press-release/how-bacteria-attack-their-host-cells-with-sticky-lollipops
Article - 30/04/2012 3D insights into the molecular teamwork in biomembranes For chemists cellular biomembranes are hard nuts to crack. It is difficult to analyze proteins that are firmly anchored in biomembranes using standard biochemical methods and it is even more difficult to investigate their three-dimensional structure and interaction with other proteins. A group of researchers led by Prof. Dr. Anne S. Ulrich at the Karlsruhe Institute of Technology KIT have developed a method that enables them to take a close look…https://www.gesundheitsindustrie-bw.de/en/article/news/3d-insights-into-the-molecular-teamwork-in-biomembranes
Article - 27/09/2010 Fraunhofer ICT – from biomass to technical materials The Pfinztal-based Fraunhofer Institute for Chemical Technology investigates and develops innovative technical materials on the basis of biobased thermoplasts and furanic resin. Innovative companies in the consumer goods, packaging and transport industries are extremely interested in such products.https://www.gesundheitsindustrie-bw.de/en/article/news/fraunhofer-ict-from-biomass-to-technical-materials
Article - 15/07/2010 A special focus on intercellular mediators Transmembrane proteins constitute around one third of all cellular proteins. Around half of all drugs that are currently on the market target the function of a specific class of transmembrane proteins, i.e. the G-protein coupled receptors. However, little is yet known about how transmembrane proteins are integrated into the membranes and how they are folded. Dr. Jörg H. Kleinschmidt hopes to shed light into the mechanisms of membrane protein…https://www.gesundheitsindustrie-bw.de/en/article/news/a-special-focus-on-intercellular-mediators
Article - 07/06/2010 Biametrics – specialist in label-free bioanalysis Biametrics is a spin-off from the University of Tübingen that focuses on the commercialisation of innovative developments in the field of label-free bioanalyses. The companys platform detects interactions between biomolecules using reflectometric interference spectroscopy RIfS and can be integrated into small mobile analytical devices.https://www.gesundheitsindustrie-bw.de/en/article/news/biametrics-specialist-in-label-free-bioanalysis
Press release - 21/05/2010 The fingerprints of molecules Prof. Heiko Möller is head of the NMR Core Facility a centre at the University of Constance that focuses on magnetic resonance spectroscopy where fingerprints of molecules are taken. The highly sensitive analysis instruments are used by his group of researchers for research projects on subjects ranging from severed visual nerves cancer protection and the rapid identification of anthrax bacteria.https://www.gesundheitsindustrie-bw.de/en/article/press-release/the-fingerprints-of-molecules
Article - 07/05/2010 Günter Gauglitz: research at the boundaries of physics, chemistry and biology Biosensors and label-free optical bioanalysis are the major research priorities of Prof. Dr. Günter Gauglitz from the Institute for Physical and Theoretical Chemistry IPC at the University of Tübingen. His whole career has been about the acquisition of multi-million third-party funded projects that are worked on by a team of 15 scientists at the IPC.https://www.gesundheitsindustrie-bw.de/en/article/news/guenter-gauglitz-research-at-the-boundaries-of-physics-chemistry-and-biology
Article - 19/04/2010 Natural antibodies to treat Alzheimer’s Alzheimers disease is characterised by changes in the substance and structure of the brain that are caused by the depositing of protein plaques in the brain. Prof. Michael Przybylski and his team of researchers at the University of Constance have deciphered the structure of the site where mouse antibodies attach to the plaques subsequently causing them to dissolve. These findings will now be used to identify the binding structure of a component…https://www.gesundheitsindustrie-bw.de/en/article/news/natural-antibodies-to-treat-alzheimer-s
Press release - 18/01/2010 Measurement instead of culture – rapid detection of Legionella There has been an unusually high frequency of Legionella infections in the city of Ulm in the period since mid-December 2009. The search for the source of the infection is well underway, although the use of traditional detection methods make it a time-consuming process. New screening methods developed by the Fraunhofer IPM could considerably reduce the time required to detect the source of infection.https://www.gesundheitsindustrie-bw.de/en/article/press-release/measurement-instead-of-culture-rapid-detection-of-legionella
Press release - 13/11/2009 Single molecules under the laser: How the genetic material is unwrapped The genetic material found in cells is not in its free state, but is bound to large protein complexes and tightly wrapped. To activate genes that could well play a role in carcinogenesis, the genetic material first needs to be unwrapped and made accessible to other cell components. Using a new biophysical method called single molecule spectroscopy, scientists from the “Biophysics of Macromolecules” division at the German Cancer Research Centre…https://www.gesundheitsindustrie-bw.de/en/article/press-release/single-molecules-under-the-laser-how-the-genetic-material-is-unwrapped
Press release - 22/09/2009 Nanoparticles: researchers to map protein corona The way nanoparticles behave in the human body not only depends on their chemical structure. Of greater importance is the way they interact with biological molecules. Professor Gerd Ulrich Nienhaus at the Karlsruhe Institute of Technology (KIT) has developed new methods that enable the quantitative measurement of these dynamic processes.https://www.gesundheitsindustrie-bw.de/en/article/press-release/nanoparticles-researchers-to-map-protein-corona
Article - 07/04/2009 Hendrik Küpper – at the service of plants and humans Prof. Hendrik Küpper had his first experience as a scientist in 1992 when together with his brother and a friend he participated in the German governments Jugend forscht contest. The students came first in biology in the national competition and first in both the Young Europeans Environmental Research Contest and the European Community Contest for Young Scientists. Back then Küpper was already interested in the interaction between heavy metals…https://www.gesundheitsindustrie-bw.de/en/article/news/hendrik-kuepper-at-the-service-of-plants-and-humans
Press release - 15/03/2009 Jürgen Wolfrum – crossing the frontiers of science The frontiers between scientific disciplines have always interested Prof. Jürgen Wolfrum a physicist who has been awarded many international prizes. Wolfrum is a pioneer in applied laser spectroscopy which he uses successfully in a variety of fields. For example in the automotive industry he uses laser spectroscopy to investigate elementary chemical reactions and combustion processes. https://www.gesundheitsindustrie-bw.de/en/article/press-release/juergen-wolfrum-crossing-the-frontiers-of-science
Press release - 08/01/2009 ILM – Organisational structure and competences In analogy to its thematic development, the ILM organisational structure previously consisted of (1) Medicine, (2) Metrology and (3) Dental Technology (DTZ) divisions. The respective areas were each managed by one individual. In line with thematic requirements, different core competences have developed over time in these areas: microscopy and biology in medicine, photothermics in metrology, tissue optics and device development in dental…https://www.gesundheitsindustrie-bw.de/en/article/press-release/ilm-organisational-structure-and-competences
Press release - 08/01/2009 ILM – Spectroscopic characterisation of substances The optical characterisation of materials through transmission, absorption and reflection is only complete when these values can also be indicated in dependence of the wavelength. In order to investigate these wavelength dependencies, the ILM has a number of high-quality spectrometers available that cover the entire range from ultraviolet to infrared light.https://www.gesundheitsindustrie-bw.de/en/article/press-release/ilm-spectroscopic-characterisation-of-substances