Dr. Andrea Toulouse from the Institute of Applied Optics receives €1.8 million in funding from the Carl-Zeiss-Stiftung as part of the CZS Nexus program to establish a new junior research group. She conducts research in the field of micro-optics and fiber-based 3D printing. Her vision is to develop 3D printers that will one day be able to build biological tissue directly inside the body.

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells. A research team from the DKFZ and the IMP in Vienna has now discovered that the acidic pH value in tumor tissue is a decisive factor in how pancreatic cancer cells adapt their energy metabolism in order to survive under these adverse conditions.

EMBL scientists created SDR-seq, a tool for single-cell DNA-RNA-sequencing that studies both DNA and RNA simultaneously, linking coding and non-coding genetic variants to gene expression in the same single cell.

Until today, the aggressiveness of prostate cancer has been assessed primarily using the Gleason grading system—an analysis of cancer tissue in a pathology laboratory that is highly subjective. An international research team led by the German Cancer Research Center (DKFZ) has now developed a novel, explainable AI model that aims to make the diagnosis of prostate cancer more transparent and less susceptible to error.

Human immunodeficiency viruses (HIV) are insidious. They can evade the immune defence and antiviral drugs by becoming "latent". In this state, they are largely invisible and unassailable. As long as these dormant viruses persist, there is no cure for HIV/AIDS. However, researchers at Ulm University Hospital have discovered a new way to reactivate latent HI viruses.